Colorado PROFILES, The Colorado Clinical and Translational Sciences Institute (CCTSI)
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Connection

Leslie Berg to Signal Transduction

This is a "connection" page, showing publications Leslie Berg has written about Signal Transduction.

 
Connection Strength
 
 
 
3.341
 
  1. Gallagher MP, Conley JM, Vangala P, Garber M, Reboldi A, Berg LJ. Hierarchy of signaling thresholds downstream of the T cell receptor and the Tec kinase ITK. Proc Natl Acad Sci U S A. 2021 08 31; 118(35).
    View in: PubMed
    Score: 0.289
  2. Cho HS, Ha S, Shin HM, Reboldi A, Hall JA, Huh JR, Usherwood EJ, Berg LJ. CD8+ T Cells Require ITK-Mediated TCR Signaling for Migration to the Intestine. Immunohorizons. 2020 02 07; 4(2):57-71.
    View in: PubMed
    Score: 0.259
  3. Conley JM, Berg LJ. TCR signaling: it's all about the numbers. Nat Immunol. 2019 11; 20(11):1415-1416.
    View in: PubMed
    Score: 0.254
  4. Prince AL, Kraus Z, Carty SA, Ng C, Yin CC, Jordan MS, Schwartzberg PL, Berg LJ. Development of innate CD4+ and CD8+ T cells in Itk-deficient mice is regulated by distinct pathways. J Immunol. 2014 Jul 15; 193(2):688-99.
    View in: PubMed
    Score: 0.175
  5. Berg LJ. Signaling pathways that regulate T cell development and differentiation. J Immunol. 2012 Dec 15; 189(12):5487-8.
    View in: PubMed
    Score: 0.158
  6. Nayar R, Enos M, Prince A, Shin H, Hemmers S, Jiang JK, Klein U, Thomas CJ, Berg LJ. TCR signaling via Tec kinase ITK and interferon regulatory factor 4 (IRF4) regulates CD8+ T-cell differentiation. Proc Natl Acad Sci U S A. 2012 Oct 09; 109(41):E2794-802.
    View in: PubMed
    Score: 0.155
  7. Andreotti AH, Schwartzberg PL, Joseph RE, Berg LJ. T-cell signaling regulated by the Tec family kinase, Itk. Cold Spring Harb Perspect Biol. 2010 Jul; 2(7):a002287.
    View in: PubMed
    Score: 0.132
  8. Shi M, Lin TH, Appell KC, Berg LJ. Cell cycle progression following naive T cell activation is independent of Jak3/common gamma-chain cytokine signals. J Immunol. 2009 Oct 01; 183(7):4493-501.
    View in: PubMed
    Score: 0.126
  9. Lucas JA, Felices M, Evans JW, Berg LJ. Subtle defects in pre-TCR signaling in the absence of the Tec kinase Itk. J Immunol. 2007 Dec 01; 179(11):7561-7.
    View in: PubMed
    Score: 0.111
  10. Berg LJ. Signalling through TEC kinases regulates conventional versus innate CD8(+) T-cell development. Nat Rev Immunol. 2007 Jun; 7(6):479-85.
    View in: PubMed
    Score: 0.108
  11. Felices M, Falk M, Kosaka Y, Berg LJ. Tec kinases in T cell and mast cell signaling. Adv Immunol. 2007; 93:145-84.
    View in: PubMed
    Score: 0.105
  12. Kosaka Y, Felices M, Berg LJ. Itk and Th2 responses: action but no reaction. Trends Immunol. 2006 Oct; 27(10):453-60.
    View in: PubMed
    Score: 0.102
  13. Mayack SR, Berg LJ. Cutting edge: an alternative pathway of CD4+ T cell differentiation is induced following activation in the absence of gamma-chain-dependent cytokine signals. J Immunol. 2006 Feb 15; 176(4):2059-63.
    View in: PubMed
    Score: 0.098
  14. Neurath MF, Berg LJ. VAV1 as a putative therapeutic target in autoimmune and chronic inflammatory diseases. Trends Immunol. 2024 Aug; 45(8):580-596.
    View in: PubMed
    Score: 0.088
  15. Miller AT, Wilcox HM, Lai Z, Berg LJ. Signaling through Itk promotes T helper 2 differentiation via negative regulation of T-bet. Immunity. 2004 Jul; 21(1):67-80.
    View in: PubMed
    Score: 0.088
  16. Yang WC, Ching KA, Tsoukas CD, Berg LJ. Tec kinase signaling in T cells is regulated by phosphatidylinositol 3-kinase and the Tec pleckstrin homology domain. J Immunol. 2001 Jan 01; 166(1):387-95.
    View in: PubMed
    Score: 0.069
  17. Conley JM, Gallagher MP, Rao A, Berg LJ. Activation of the Tec Kinase ITK Controls Graded IRF4 Expression in Response to Variations in TCR Signal Strength. J Immunol. 2020 07 15; 205(2):335-345.
    View in: PubMed
    Score: 0.066
  18. Bunnell SC, Diehn M, Yaffe MB, Findell PR, Cantley LC, Berg LJ. Biochemical interactions integrating Itk with the T cell receptor-initiated signaling cascade. J Biol Chem. 2000 Jan 21; 275(3):2219-30.
    View in: PubMed
    Score: 0.065
  19. Liu KQ, Bunnell SC, Gurniak CB, Berg LJ. T cell receptor-initiated calcium release is uncoupled from capacitative calcium entry in Itk-deficient T cells. J Exp Med. 1998 May 18; 187(10):1721-7.
    View in: PubMed
    Score: 0.057
  20. Andreotti AH, Joseph RE, Conley JM, Iwasa J, Berg LJ. Multidomain Control Over TEC Kinase Activation State Tunes the T Cell Response. Annu Rev Immunol. 2018 04 26; 36:549-578.
    View in: PubMed
    Score: 0.057
  21. Bunnell SC, Berg LJ. The signal transduction of motion and antigen recognition: factors affecting T cell function and differentiation. Genet Eng (N Y). 1998; 20:63-110.
    View in: PubMed
    Score: 0.056
  22. Thomis DC, Lee W, Berg LJ. T cells from Jak3-deficient mice have intact TCR signaling, but increased apoptosis. J Immunol. 1997 Nov 15; 159(10):4708-19.
    View in: PubMed
    Score: 0.056
  23. Nayar R, Schutten E, Jangalwe S, Durost PA, Kenney LL, Conley JM, Daniels K, Brehm MA, Welsh RM, Berg LJ. IRF4 Regulates the Ratio of T-Bet to Eomesodermin in CD8+ T Cells Responding to Persistent LCMV Infection. PLoS One. 2015; 10(12):e0144826.
    View in: PubMed
    Score: 0.049
  24. Nayar R, Schutten E, Bautista B, Daniels K, Prince AL, Enos M, Brehm MA, Swain SL, Welsh RM, Berg LJ. Graded levels of IRF4 regulate CD8+ T cell differentiation and expansion, but not attrition, in response to acute virus infection. J Immunol. 2014 Jun 15; 192(12):5881-93.
    View in: PubMed
    Score: 0.044
  25. Shin HM, Kapoor V, Guan T, Kaech SM, Welsh RM, Berg LJ. Epigenetic modifications induced by Blimp-1 Regulate CD8? T cell memory progression during acute virus infection. Immunity. 2013 Oct 17; 39(4):661-75.
    View in: PubMed
    Score: 0.042
  26. Joseph RE, Kleino I, Wales TE, Xie Q, Fulton DB, Engen JR, Berg LJ, Andreotti AH. Activation loop dynamics determine the different catalytic efficiencies of B cell- and T cell-specific tec kinases. Sci Signal. 2013 Aug 27; 6(290):ra76.
    View in: PubMed
    Score: 0.041
  27. Heyeck SD, Berg LJ. Developmental regulation of a murine T-cell-specific tyrosine kinase gene, Tsk. Proc Natl Acad Sci U S A. 1993 Jan 15; 90(2):669-73.
    View in: PubMed
    Score: 0.040
  28. Marshall HD, Prince AL, Berg LJ, Welsh RM. IFN-alpha beta and self-MHC divert CD8 T cells into a distinct differentiation pathway characterized by rapid acquisition of effector functions. J Immunol. 2010 Aug 01; 185(3):1419-28.
    View in: PubMed
    Score: 0.033
  29. Min L, Wu W, Joseph RE, Fulton DB, Berg L, Andreotti AH. Disrupting the intermolecular self-association of Itk enhances T cell signaling. J Immunol. 2010 Apr 15; 184(8):4228-35.
    View in: PubMed
    Score: 0.033
  30. Berg LJ. Strength of T cell receptor signaling strikes again. Immunity. 2009 Oct 16; 31(4):529-31.
    View in: PubMed
    Score: 0.032
  31. Prince AL, Yin CC, Enos ME, Felices M, Berg LJ. The Tec kinases Itk and Rlk regulate conventional versus innate T-cell development. Immunol Rev. 2009 Mar; 228(1):115-31.
    View in: PubMed
    Score: 0.030
  32. Shi M, Lin TH, Appell KC, Berg LJ. Janus-kinase-3-dependent signals induce chromatin remodeling at the Ifng locus during T helper 1 cell differentiation. Immunity. 2008 Jun; 28(6):763-73.
    View in: PubMed
    Score: 0.029
  33. Felices M, Berg LJ. The Tec kinases Itk and Rlk regulate NKT cell maturation, cytokine production, and survival. J Immunol. 2008 Mar 01; 180(5):3007-18.
    View in: PubMed
    Score: 0.028
  34. Li CR, Berg LJ. Itk is not essential for CD28 signaling in naive T cells. J Immunol. 2005 Apr 15; 174(8):4475-9.
    View in: PubMed
    Score: 0.023
  35. Berg LJ, Finkelstein LD, Lucas JA, Schwartzberg PL. Tec family kinases in T lymphocyte development and function. Annu Rev Immunol. 2005; 23:549-600.
    View in: PubMed
    Score: 0.023
  36. Berg LJ, Nussenzweig M. Signals that regulate lymphocyte development and differentiation. Curr Opin Immunol. 2004 Apr; 16(2):163-6.
    View in: PubMed
    Score: 0.022
  37. Lucas JA, Miller AT, Atherly LO, Berg LJ. The role of Tec family kinases in T cell development and function. Immunol Rev. 2003 Feb; 191:119-38.
    View in: PubMed
    Score: 0.020
  38. Lucas JA, Atherly LO, Berg LJ. The absence of Itk inhibits positive selection without changing lineage commitment. J Immunol. 2002 Jun 15; 168(12):6142-51.
    View in: PubMed
    Score: 0.019
  39. Soldevila G, Castellanos C, Malissen M, Berg LJ. Analysis of the individual role of the TCRzeta chain in transgenic mice after conditional activation with chemical inducers of dimerization. Cell Immunol. 2001 Dec 15; 214(2):123-38.
    View in: PubMed
    Score: 0.018
  40. Cui Y, Hackenmiller R, Berg L, Jean F, Nakayama T, Thomas G, Christian JL. The activity and signaling range of mature BMP-4 is regulated by sequential cleavage at two sites within the prodomain of the precursor. Genes Dev. 2001 Nov 01; 15(21):2797-802.
    View in: PubMed
    Score: 0.018
  41. Baird AM, Lucas JA, Berg LJ. A profound deficiency in thymic progenitor cells in mice lacking Jak3. J Immunol. 2000 Oct 01; 165(7):3680-8.
    View in: PubMed
    Score: 0.017
  42. Thomis DC, Berg LJ. The role of Jak3 in lymphoid development, activation, and signaling. Curr Opin Immunol. 1997 Aug; 9(4):541-7.
    View in: PubMed
    Score: 0.014
  43. Thomis DC, Berg LJ. Peripheral expression of Jak3 is required to maintain T lymphocyte function. J Exp Med. 1997 Jan 20; 185(2):197-206.
    View in: PubMed
    Score: 0.013
  44. Yelon D, Spain LM, Lim K, Berg LJ. Alterations in CD4 dependence accompany T cell development and differentiation. Int Immunol. 1996 Jul; 8(7):1077-90.
    View in: PubMed
    Score: 0.013
  45. Raab M, Cai YC, Bunnell SC, Heyeck SD, Berg LJ, Rudd CE. p56Lck and p59Fyn regulate CD28 binding to phosphatidylinositol 3-kinase, growth factor receptor-bound protein GRB-2, and T cell-specific protein-tyrosine kinase ITK: implications for T-cell costimulation. Proc Natl Acad Sci U S A. 1995 Sep 12; 92(19):8891-5.
    View in: PubMed
    Score: 0.012
  46. Wu T, Shin HM, Moseman EA, Ji Y, Huang B, Harly C, Sen JM, Berg LJ, Gattinoni L, McGavern DB, Schwartzberg PL. TCF1 Is Required for the T Follicular Helper Cell Response to Viral Infection. Cell Rep. 2015 Sep 29; 12(12):2099-110.
    View in: PubMed
    Score: 0.012
  47. Pereira RM, Martinez GJ, Engel I, Cruz-Guilloty F, Barboza BA, Tsagaratou A, Lio CW, Berg LJ, Lee Y, Kronenberg M, Bandukwala HS, Rao A. Jarid2 is induced by TCR signalling and controls iNKT cell maturation. Nat Commun. 2014 Aug 08; 5:4540.
    View in: PubMed
    Score: 0.011
  48. Jain N, Miu B, Jiang JK, McKinstry KK, Prince A, Swain SL, Greiner DL, Thomas CJ, Sanderson MJ, Berg LJ, Kang J. CD28 and ITK signals regulate autoreactive T cell trafficking. Nat Med. 2013 Dec; 19(12):1632-7.
    View in: PubMed
    Score: 0.011
  49. Malhotra N, Narayan K, Cho OH, Sylvia KE, Yin C, Melichar H, Rashighi M, Lefebvre V, Harris JE, Berg LJ, Kang J. A network of high-mobility group box transcription factors programs innate interleukin-17 production. Immunity. 2013 Apr 18; 38(4):681-93.
    View in: PubMed
    Score: 0.010
  50. Berg LJ. Generation of the T cell repertoire. Curr Opin Immunol. 1989 Oct; 2(1):87-92.
    View in: PubMed
    Score: 0.008
  51. Kammer W, Lischke A, Moriggl R, Groner B, Ziemiecki A, Gurniak CB, Berg LJ, Friedrich K. Homodimerization of interleukin-4 receptor alpha chain can induce intracellular signaling. J Biol Chem. 1996 Sep 27; 271(39):23634-7.
    View in: PubMed
    Score: 0.003
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.

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