 Antifibrinolytic Agents
"Antifibrinolytic Agents" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Agents that prevent fibrinolysis or lysis of a blood clot or thrombus. Several endogenous antiplasmins are known. The drugs are used to control massive hemorrhage and in other coagulation disorders.
| Descriptor ID |
D000933
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| MeSH Number(s) |
D27.505.519.421.500 D27.505.954.502.270.463.091
|
| Concept/Terms |
Plasmin Inhibitors- Plasmin Inhibitors
- Inhibitors, Plasmin
- Antiplasmins
- Plasmin Inhibitor
- Inhibitor, Plasmin
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Below are MeSH descriptors whose meaning is more general than "Antifibrinolytic Agents".
Below are MeSH descriptors whose meaning is more specific than "Antifibrinolytic Agents".
This graph shows the total number of publications written about "Antifibrinolytic Agents" by people in this website by year, and whether "Antifibrinolytic Agents" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 1 | 0 | 1 | | 2001 | 1 | 0 | 1 | | 2006 | 0 | 1 | 1 | | 2007 | 1 | 0 | 1 | | 2010 | 1 | 0 | 1 | | 2012 | 1 | 0 | 1 | | 2013 | 2 | 0 | 2 | | 2014 | 2 | 1 | 3 | | 2015 | 1 | 0 | 1 | | 2016 | 0 | 1 | 1 | | 2017 | 2 | 0 | 2 | | 2018 | 0 | 1 | 1 | | 2019 | 1 | 3 | 4 | | 2020 | 1 | 0 | 1 | | 2022 | 2 | 0 | 2 | | 2023 | 7 | 0 | 7 | | 2024 | 1 | 0 | 1 |
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Below are the most recent publications written about "Antifibrinolytic Agents" by people in Profiles.
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Huneault HE, Gent AE, Cohen CC, He Z, Jarrell ZR, Kamaleswaran R, Vos MB. Validation of a screening panel for pediatric metabolic dysfunction-associated steatotic liver disease using metabolomics. Hepatol Commun. 2024 Mar 01; 8(3).
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Haberkorn CJ, Severance CC, Wetmore NC, West WG, Ng PC, Cendali F, Pitotti C, Schauer SG, Maddry JK, Bebarta VS, Hendry-Hofer TB. Intramuscular administration of tranexamic acid in a large swine model of hemorrhage with hyperfibrinolysis. J Trauma Acute Care Surg. 2024 May 01; 96(5):735-741.
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Hess CN, Hsia J, Carroll IA, Nehler MR, Ruf W, Morrow DA, Nicolau JC, Berwanger O, Szarek M, Capell WH, Johri S, Pursley MS, Gupta R, Meehan PS, Franchi F, Effron MB, Marshall D, Graybill CA, Huebler SP, Keuer T, Bristow MR, Bonaca MP. Novel Tissue Factor Inhibition for Thromboprophylaxis in COVID-19: Primary Results of the ASPEN-COVID-19 Trial. Arterioscler Thromb Vasc Biol. 2023 08; 43(8):1572-1582.
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Marquez SA, Crosby K, Patil B, Avila C, Ibrahim AM, Pessoa H, Singh J. Hydroxy proline and gamma-aminobutyric acid: markers of susceptibility to vine decline disease caused by the fungus Monosporascus cannonballus in melons (Cucumis melo L.). PeerJ. 2023; 11:e14932.
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Coleman JR, Moore EE, Kelher MR, Jones K, Cohen MJ, Banerjee A, Silliman CC. Elucidating the molecular mechanisms of fibrinolytic shutdown after severe injury: The role of thrombin-activatable fibrinolysis inhibitor. J Trauma Acute Care Surg. 2023 06 01; 94(6):857-862.
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Khanwalkar A, Chan E, Roozdar P, Kim D, Ma Y, Hwang PH, Nayak JV, Patel ZM. Tranexamic acid does not significantly lower postoperative bleeding after endoscopic sinus and nasal surgery. Int Forum Allergy Rhinol. 2023 09; 13(9):1584-1591.
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Baidwan NK, Schauer SG, Dixon JM, Bhaumik S, April MD, April MD, Dengler BA, Mould-Millman NK. Tranexamic Acid Improves Survival in the Setting of Severe Head Injury in Combat Casualties. Med J (Ft Sam Houst Tex). 2023 Jan-Mar; (Per 23-1/2/3):34-40.
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Coburn W, Trottier Z, Villarreal RI, Paulson MW, Woodard SC, McKay JT, Bebarta VS, Flarity K, Keenan S, Schauer SG. Prehospital Pharmacotherapy in Moderate and Severe Traumatic Brain Injury: A Systematic Review. Med J (Ft Sam Houst Tex). 2023 Jan-Mar; (Per 23-1/2/3):47-56.
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Miangul S, Oluwaremi T, El Haddad J, Adra M, Pinnawala N, Nakanishi H, Matar RH, Than CA, Stewart TM. Update on the efficacy and safety of intravenous tranexamic acid in hip fracture surgery: a systematic review and meta-analysis. Eur J Orthop Surg Traumatol. 2023 Jul; 33(5):2179-2190.
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Spinella PC, Bochicchio K, Thomas KA, Staudt A, Shea SM, Pusateri AE, Schuerer D, Levy JH, Cap AP, Bochicchio G. The risk of thromboembolic events with early intravenous 2- and 4-g bolus dosing of tranexamic acid compared to placebo in patients with severe traumatic bleeding: A secondary analysis of a randomized, double-blind, placebo-controlled, single-center trial. Transfusion. 2022 08; 62 Suppl 1:S139-S150.
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