Cortical Spreading Depression
"Cortical Spreading Depression" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The decrease in neuronal activity (related to a decrease in metabolic demand) extending from the site of cortical stimulation. It is believed to be responsible for the decrease in cerebral blood flow that accompanies the aura of MIGRAINE WITH AURA. (Campbell's Psychiatric Dictionary, 8th ed.)
Descriptor ID |
D013181
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MeSH Number(s) |
G11.561.200.500.300
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Concept/Terms |
Cortical Spreading Depression- Cortical Spreading Depression
- Cortical Spreading Depressions
- Depression, Cortical Spreading
- Depressions, Cortical Spreading
- Spreading Depression, Cortical
- Spreading Depressions, Cortical
- Spreading Depression of Leao
- Leao Spreading Depression
- Cortical Depression, Spreading
- Cortical Depressions, Spreading
- Depression, Spreading Cortical
- Depressions, Spreading Cortical
- Spreading Cortical Depressions
- Spreading Cortical Depression
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Below are MeSH descriptors whose meaning is more general than "Cortical Spreading Depression".
Below are MeSH descriptors whose meaning is more specific than "Cortical Spreading Depression".
This graph shows the total number of publications written about "Cortical Spreading Depression" by people in this website by year, and whether "Cortical Spreading Depression" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2008 | 1 | 0 | 1 | 2009 | 1 | 0 | 1 | 2010 | 1 | 1 | 2 | 2013 | 1 | 1 | 2 | 2015 | 1 | 1 | 2 | 2016 | 1 | 0 | 1 | 2017 | 1 | 0 | 1 | 2020 | 0 | 1 | 1 | 2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "Cortical Spreading Depression" by people in Profiles.
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Bertels Z, Singh H, Dripps I, Siegersma K, Tipton AF, Witkowski WD, Sheets Z, Shah P, Conway C, Mangutov E, Ao M, Petukhova V, Karumudi B, Petukhov PA, Baca SM, Rasenick MM, Pradhan AA. Neuronal complexity is attenuated in preclinical models of migraine and restored by HDAC6 inhibition. Elife. 2021 04 15; 10.
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Dripps IJ, Bertels Z, Moye LS, Tipton AF, Siegersma K, Baca SM, Kieffer BL, Pradhan AA. Forebrain delta opioid receptors regulate the response of delta agonist in models of migraine and opioid-induced hyperalgesia. Sci Rep. 2020 10 19; 10(1):17629.
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Kramer DR, Fujii T, Ohiorhenuan I, Liu CY. Interplay between Cortical Spreading Depolarization and Seizures. Stereotact Funct Neurosurg. 2017; 95(1):1-5.
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Houben T, Loonen IC, Baca SM, Schenke M, Meijer JH, Ferrari MD, Terwindt GM, Voskuyl RA, Charles A, van den Maagdenberg AM, Tolner EA. Optogenetic induction of cortical spreading depression in anesthetized and freely behaving mice. J Cereb Blood Flow Metab. 2017 May; 37(5):1641-1655.
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Kaufmann D, Bates EA, Yagen B, Bialer M, Saunders GH, Wilcox K, White HS, Brennan KC. sec-Butylpropylacetamide (SPD) has antimigraine properties. Cephalalgia. 2016 Sep; 36(10):924-35.
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Kramer DR, Fujii T, Ohiorhenuan I, Liu CY. Cortical spreading depolarization: Pathophysiology, implications, and future directions. J Clin Neurosci. 2016 Feb; 24:22-7.
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Charles AC, Baca SM. Cortical spreading depression and migraine. Nat Rev Neurol. 2013 Nov; 9(11):637-44.
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Brennan KC, Bates EA, Shapiro RE, Zyuzin J, Hallows WC, Huang Y, Lee HY, Jones CR, Fu YH, Charles AC, Pt?cek LJ. Casein kinase id mutations in familial migraine and advanced sleep phase. Sci Transl Med. 2013 May 01; 5(183):183ra56, 1-11.
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Kluger BM, Palmer C, Shattuck JT, Triggs WJ. Motor evoked potential depression following repetitive central motor initiation. Exp Brain Res. 2012 Feb; 216(4):585-90.
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Carter RE, Aiba I, Dietz RM, Sheline CT, Shuttleworth CW. Spreading depression and related events are significant sources of neuronal Zn2+ release and accumulation. J Cereb Blood Flow Metab. 2011 Apr; 31(4):1073-84.
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