 Linoleic Acid
"Linoleic Acid" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A doubly unsaturated fatty acid, occurring widely in plant glycosides. It is an essential fatty acid in mammalian nutrition and is used in the biosynthesis of prostaglandins and cell membranes. (From Stedman, 26th ed)
| Descriptor ID |
D019787
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| MeSH Number(s) |
D10.251.355.310.515.500 D10.251.355.343.500.500
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| Concept/Terms |
Linoleic Acid- Linoleic Acid
- 9,12-Octadecadienoic Acid
- 9,12 Octadecadienoic Acid
- Acid, 9,12-Octadecadienoic
Linolelaidic Acid- Linolelaidic Acid
- trans,trans-9,12-Octadecadienoic Acid
- Linoleic Acid, (E,E)-Isomer
- 9-trans,12-trans-Octadecadienoic Acid
- 9 trans,12 trans Octadecadienoic Acid
- Linoelaidic Acid
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Below are MeSH descriptors whose meaning is more general than "Linoleic Acid".
Below are MeSH descriptors whose meaning is more specific than "Linoleic Acid".
This graph shows the total number of publications written about "Linoleic Acid" by people in this website by year, and whether "Linoleic Acid" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 1 | 1 | | 2002 | 0 | 1 | 1 | | 2004 | 1 | 1 | 2 | | 2006 | 1 | 0 | 1 | | 2008 | 2 | 0 | 2 | | 2009 | 2 | 1 | 3 | | 2012 | 1 | 0 | 1 | | 2014 | 1 | 1 | 2 | | 2015 | 1 | 4 | 5 | | 2016 | 1 | 0 | 1 | | 2017 | 2 | 1 | 3 | | 2019 | 1 | 1 | 2 | | 2020 | 1 | 1 | 2 | | 2021 | 0 | 2 | 2 | | 2022 | 2 | 0 | 2 | | 2023 | 2 | 0 | 2 |
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Below are the most recent publications written about "Linoleic Acid" by people in Profiles.
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Mahler CA, Snoke DB, Cole RM, Angelotti A, Sparagna GC, Baskin KK, Ni A, Belury MA. Consuming a Linoleate-Rich Diet Increases Concentrations of Tetralinoleoyl Cardiolipin in Mouse Liver and Alters Hepatic Mitochondrial Respiration. J Nutr. 2024 Mar; 154(3):856-865.
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Momin SR, Senn MK, Manichaikul A, Yang C, Mathias R, Phan M, Rich SS, Sergeant S, Seeds M, Reynolds L, Chilton FH, Wood AC. Dietary Sources of Linoleic Acid (LA) Differ by Race/Ethnicity in Adults Participating in the National Health and Nutrition Examination Survey (NHANES) between 2017-2018. Nutrients. 2023 Jun 16; 15(12).
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Lynch DR, Mathews KD, Perlman S, Zesiewicz T, Subramony S, Omidvar O, Vogel AP, Krtolica A, Litterman N, van der Ploeg L, Heerinckx F, Milner P, Midei M. Double blind trial of a deuterated form of linoleic acid (RT001) in Friedreich ataxia. J Neurol. 2023 Mar; 270(3):1615-1623.
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Cole RM, Angelotti A, Sparagna GC, Ni A, Belury MA. Linoleic Acid-Rich Oil Alters Circulating Cardiolipin Species and Fatty Acid Composition in Adults: A Randomized Controlled Trial. Mol Nutr Food Res. 2022 08; 66(15):e2101132.
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Buckner T, Vanderlinden LA, DeFelice BC, Carry PM, Kechris K, Dong F, Fiehn O, Frohnert BI, Clare-Salzler M, Rewers M, Norris JM. The oxylipin profile is associated with development of type 1 diabetes: the Diabetes Autoimmunity Study in the Young (DAISY). Diabetologia. 2021 08; 64(8):1785-1794.
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Dong S, Wang Q, Kao YR, Diaz A, Tasset I, Kaushik S, Thiruthuvanathan V, Zintiridou A, Nieves E, Dzieciatkowska M, Reisz JA, Gavathiotis E, D'Alessandro A, Will B, Cuervo AM. Chaperone-mediated autophagy sustains haematopoietic stem-cell function. Nature. 2021 03; 591(7848):117-123.
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Wren SN, Donovan MG, Selmin OI, Doetschman TC, Romagnolo DF. A Villin-Driven Fxr Transgene Modulates Enterohepatic Bile Acid Homeostasis and Response to an n-6-Enriched High-Fat Diet. Int J Mol Sci. 2020 Oct 22; 21(21).
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Sergeant S, Hallmark B, Mathias RA, Mustin TL, Ivester P, Bohannon ML, Ruczinski I, Johnstone L, Seeds MC, Chilton FH. Prospective clinical trial examining the impact of genetic variation in FADS1 on the metabolism of linoleic acid- and ?-linolenic acid-containing botanical oils. Am J Clin Nutr. 2020 05 01; 111(5):1068-1078.
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Knez M, Pantovic A, Zekovic M, Pavlovic Z, Glibetic M, Zec M. Is There a Link between Zinc Intake and Status with Plasma Fatty Acid Profile and Desaturase Activities in Dyslipidemic Subjects? Nutrients. 2019 Dec 28; 12(1).
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Romagnolo DF, Donovan MG, Doetschman TC, Selmin OI. n-6 Linoleic Acid Induces Epigenetics Alterations Associated with Colonic Inflammation and Cancer. Nutrients. 2019 Jan 15; 11(1).
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