 Hirschsprung Disease
"Hirschsprung Disease" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Congenital MEGACOLON resulting from the absence of ganglion cells (aganglionosis) in a distal segment of the LARGE INTESTINE. The aganglionic segment is permanently contracted thus causing dilatation proximal to it. In most cases, the aganglionic segment is within the RECTUM and SIGMOID COLON.
| Descriptor ID |
D006627
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| MeSH Number(s) |
C06.198.439 C06.405.469.158.701.439 C16.131.314.439
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| Concept/Terms |
Hirschsprung Disease- Hirschsprung Disease
- Disease, Hirschsprung
- Megacolon, Congenital
- Hirschsprung's Disease
- Disease, Hirschsprung's
- Hirschsprungs Disease
- Megacolon, Aganglionic
- Aganglionic Megacolon
- Congenital Megacolon
Aganglionosis, Colonic- Aganglionosis, Colonic
- Colonic Aganglionosis
- Total Colonic Aganglionosis
- Aganglionosis, Total Colonic
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Below are MeSH descriptors whose meaning is more general than "Hirschsprung Disease".
Below are MeSH descriptors whose meaning is more specific than "Hirschsprung Disease".
This graph shows the total number of publications written about "Hirschsprung Disease" by people in this website by year, and whether "Hirschsprung Disease" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 1 | 0 | 1 | | 1996 | 0 | 1 | 1 | | 1997 | 3 | 0 | 3 | | 1998 | 1 | 1 | 2 | | 1999 | 3 | 0 | 3 | | 2003 | 1 | 0 | 1 | | 2010 | 3 | 0 | 3 | | 2011 | 1 | 0 | 1 | | 2012 | 0 | 2 | 2 | | 2013 | 2 | 0 | 2 | | 2014 | 2 | 0 | 2 | | 2015 | 6 | 0 | 6 | | 2016 | 4 | 0 | 4 | | 2017 | 3 | 0 | 3 | | 2018 | 3 | 0 | 3 | | 2019 | 3 | 0 | 3 | | 2020 | 2 | 1 | 3 | | 2021 | 6 | 0 | 6 | | 2022 | 5 | 0 | 5 | | 2023 | 6 | 0 | 6 | | 2024 | 3 | 0 | 3 | | 2025 | 1 | 0 | 1 |
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Below are the most recent publications written about "Hirschsprung Disease" by people in Profiles.
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Vincent SA, Evans LL, Tong S, Mashhadi MP, Arnold M, Lovell M, Bischoff A, De La Torre L. Does the absence of hypertrophic nerves on rectal biopsy predict long-segment or total colonic aganglionosis? Pediatr Surg Int. 2025 Jun 04; 41(1):158.
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Gerardo RG, Denning NL, Yancey CL, Yancey AG, Yancey AH, Newman EA, Gosain A, Ford HR, Frischer JS, Levitt MA. The Story of Dr. Asa G. Yancey and Surgical Innovation in the Face of Discrimination. J Surg Res. 2024 Oct; 302:A1-A5.
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Rentea RM, Bokova E, Frischer JS, Gosain A, Langer JC, Levitt MA, Nandivada P, Rialon KL, Rollins MD, Segura B, Wood RJ, Lim IIP. Evaluation and Management of Total Colonic Hirschsprung Disease: A Comprehensive Review From the American Pediatric Surgical Association (APSA) Hirschsprung Disease Interest Group. J Pediatr Surg. 2024 Nov; 59(11):161677.
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Wehrli LA, Harris KT, Wood DT, Wilcox DT, Cooper EH, Rieck JM, McGuire E, Ketzer J, De La Torre L, Pe?a A, Bischoff A. Urological outcomes in adult females born with anorectal malformation or Hirschsprung disease. Pediatr Surg Int. 2024 Jul 06; 40(1):179.
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Montalva L, Cheng LS, Kapur R, Langer JC, Berrebi D, Kyrklund K, Pakarinen M, de Blaauw I, Bonnard A, Gosain A. Hirschsprung disease. Nat Rev Dis Primers. 2023 Oct 12; 9(1):54.
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Bischoff A, Hayes K, Guimaraes C, Merritt A, Wickham M, Schneider L, Martin H, Ketzer J, Rodriguez V, Pe?a A, De La Torre L. Standardization of radiograph readings during bowel management week. Pediatr Surg Int. 2023 Jul 20; 39(1):236.
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Wehrli LA, Reppucci ML, De La Torre L, Ketzer J, Rieck JM, Cooper EH, Judd-Glossy L, Pe?a A, Bischoff A. Gastrointestinal quality of life and bowel function in adults born with anorectal malformation and hirschsprung disease. Pediatr Surg Int. 2023 Jul 18; 39(1):234.
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Wehrli LA, Reppucci ML, Ketzer J, Dominguez-Mu?oz A, Cooper EH, Pe?a A, Bischoff A, De La Torre L. Incidence of medullary thyroid carcinoma and Hirschsprung disease based on the cosmos database. Pediatr Surg Int. 2023 Jul 07; 39(1):227.
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Sutthatarn P, Lapidus-Krol E, Smith C, Halaweish I, Rialon K, Ralls MW, Rentea RM, Madonna MB, Haddock C, Rocca AM, Gosain A, Frischer J, Piper H, Goldstein AM, Saadai P, Durham MM, Dickie B, Jafri M, Langer JC. Hirschsprung-associated inflammatory bowel disease: A multicenter study from the APSA Hirschsprung disease interest group. J Pediatr Surg. 2023 May; 58(5):856-861.
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Torre LD, Dom?nguez A, Arnold M, Lovell M, Mart?nez D, Bischoff A, Wehrli L. Histological transitional zone pull-through in Hirschsprung disease. Postoperative functional results and current recommendations. Bol Med Hosp Infant Mex. 2023; 80(6):331-338.
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