 Heparan Sulfate Proteoglycans
"Heparan Sulfate Proteoglycans" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Ubiquitous macromolecules associated with the cell surface and extracellular matrix of a wide range of cells of vertebrate and invertebrate tissues. They are essential cofactors in cell-matrix adhesion processes, in cell-cell recognition systems, and in receptor-growth factor interactions. (From Cancer Metastasis Rev 1996; 15(2): 177-86; Hepatology 1996; 24(3): 524-32)
| Descriptor ID |
D019812
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| MeSH Number(s) |
D09.698.373.425.500 D09.698.735.400 D12.776.395.650.350
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| Concept/Terms |
Heparan Sulfate Proteoglycans- Heparan Sulfate Proteoglycans
- Proteoglycans, Heparan Sulfate
- Sulfate Proteoglycans, Heparan
- HSPG
- Proteoheparan Sulfate
- Heparan Sulfate Proteoglycan
- Proteoglycan, Heparan Sulfate
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Below are MeSH descriptors whose meaning is more general than "Heparan Sulfate Proteoglycans".
Below are MeSH descriptors whose meaning is more specific than "Heparan Sulfate Proteoglycans".
This graph shows the total number of publications written about "Heparan Sulfate Proteoglycans" by people in this website by year, and whether "Heparan Sulfate Proteoglycans" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 1 | 0 | 1 | | 1999 | 1 | 0 | 1 | | 2000 | 1 | 0 | 1 | | 2001 | 0 | 1 | 1 | | 2002 | 0 | 1 | 1 | | 2003 | 3 | 0 | 3 | | 2006 | 1 | 0 | 1 | | 2007 | 0 | 1 | 1 | | 2013 | 0 | 1 | 1 | | 2014 | 1 | 0 | 1 | | 2016 | 1 | 1 | 2 |
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Below are the most recent publications written about "Heparan Sulfate Proteoglycans" by people in Profiles.
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Oshima K, King SI, McMurtry SA, Schmidt EP. Endothelial Heparan Sulfate Proteoglycans in Sepsis: The Role of the Glycocalyx. Semin Thromb Hemost. 2021 Apr; 47(3):274-282.
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Arthur A, McCall PJ, Jolly L, Kinsella J, Kirk A, Shelley BG. Endothelial glycocalyx layer shedding following lung resection. Biomark Med. 2016 Oct; 10(10):1033-1038.
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Xu X, Li Z, Leng Y, Neu CP, Calve S. Knockdown of the pericellular matrix molecule perlecan lowers in situ cell and matrix stiffness in developing cartilage. Dev Biol. 2016 10 15; 418(2):242-7.
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Baschal EE, Wethey CI, Swindle K, Baschal RM, Gowan K, Tang NL, Alvarado DM, Haller GE, Dobbs MB, Taylor MR, Gurnett CA, Jones KL, Miller NH. Exome sequencing identifies a rare HSPG2 variant associated with familial idiopathic scoliosis. G3 (Bethesda). 2014 Dec 12; 5(2):167-74.
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Razzaghi H, Tempczyk-Russell A, Haubold K, Santorico SA, Shokati T, Christians U, Churchill ME. Genetic and structure-function studies of missense mutations in human endothelial lipase. PLoS One. 2013; 8(3):e55716.
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Cushing MC, Liao JT, Jaeggli MP, Anseth KS. Material-based regulation of the myofibroblast phenotype. Biomaterials. 2007 Aug; 28(23):3378-87.
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Boyle MP, Enke RA, Reynolds JB, Mogayzel PJ, Guggino WB, Zeitlin PL. Membrane-associated heparan sulfate is not required for rAAV-2 infection of human respiratory epithelia. Virol J. 2006 Apr 22; 3:29.
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Garl PJ, Wenzlau JM, Walker HA, Whitelock JM, Costell M, Weiser-Evans MC. Perlecan-induced suppression of smooth muscle cell proliferation is mediated through increased activity of the tumor suppressor PTEN. Circ Res. 2004 Feb 06; 94(2):175-83.
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Kinsella MG, Tran PK, Weiser-Evans MC, Reidy M, Majack RA, Wight TN. Changes in perlecan expression during vascular injury: role in the inhibition of smooth muscle cell proliferation in the late lesion. Arterioscler Thromb Vasc Biol. 2003 Apr 01; 23(4):608-14.
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Walker HA, Whitelock JM, Garl PJ, Nemenoff RA, Stenmark KR, Weiser-Evans MC. Perlecan up-regulation of FRNK suppresses smooth muscle cell proliferation via inhibition of FAK signaling. Mol Biol Cell. 2003 May; 14(5):1941-52.
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