 IMP Dehydrogenase
"IMP Dehydrogenase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme that catalyzes the dehydrogenation of inosine 5'-phosphate to xanthosine 5'-phosphate in the presence of NAD. EC 1.1.1.205.
| Descriptor ID |
D007168
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| MeSH Number(s) |
D08.811.682.047.820.450
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| Concept/Terms |
IMP Dehydrogenase- IMP Dehydrogenase
- Dehydrogenase, IMP
- Inosinic Acid Dehydrogenase
- Acid Dehydrogenase, Inosinic
- Dehydrogenase, Inosinic Acid
- Inosine-5-Monophosphate Dehydrogenase
- Dehydrogenase, Inosine-5-Monophosphate
- Inosine 5 Monophosphate Dehydrogenase
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Below are MeSH descriptors whose meaning is more general than "IMP Dehydrogenase".
Below are MeSH descriptors whose meaning is more specific than "IMP Dehydrogenase".
This graph shows the total number of publications written about "IMP Dehydrogenase" by people in this website by year, and whether "IMP Dehydrogenase" was a major or minor topic of these publications.
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Below are the most recent publications written about "IMP Dehydrogenase" by people in Profiles.
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Smits TA, Cox S, Fukuda T, Sherbotie JR, Ward RM, Goebel J, Vinks AA. Effects of unbound mycophenolic acid on inosine monophosphate dehydrogenase inhibition in pediatric kidney transplant patients. Ther Drug Monit. 2014 Dec; 36(6):716-23.
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Dong M, Fukuda T, Cox S, de Vries MT, Hooper DK, Goebel J, Vinks AA. Population pharmacokinetic-pharmacodynamic modelling of mycophenolic acid in paediatric renal transplant recipients in the early post-transplant period. Br J Clin Pharmacol. 2014 Nov; 78(5):1102-12.
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Fukuda T, Goebel J, Th?gersen H, Maseck D, Cox S, Logan B, Sherbotie J, Seikaly M, Vinks AA. Inosine monophosphate dehydrogenase (IMPDH) activity as a pharmacodynamic biomarker of mycophenolic acid effects in pediatric kidney transplant recipients. J Clin Pharmacol. 2011 Mar; 51(3):309-20.
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Chen L, Petrelli R, Olesiak M, Wilson DJ, Labello NP, Pankiewicz KW. Bis(sulfonamide) isosters of mycophenolic adenine dinucleotide analogues: inhibition of inosine monophosphate dehydrogenase. Bioorg Med Chem. 2008 Aug 01; 16(15):7462-9.
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Rejman D, Olesiak M, Chen L, Patterson SE, Wilson D, Jayaram HN, Hedstrom L, Pankiewicz KW. Novel methylenephosphophosphonate analogues of mycophenolic adenine dinucleotide. Inhibition of inosine monophosphate dehydrogenase. J Med Chem. 2006 Aug 10; 49(16):5018-22.
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Yam P, Jensen M, Akkina R, Anderson J, Villacres MC, Wu J, Zaia JA, Yee JK. Ex vivo selection and expansion of cells based on expression of a mutated inosine monophosphate dehydrogenase 2 after HIV vector transduction: effects on lymphocytes, monocytes, and CD34+ stem cells. Mol Ther. 2006 Aug; 14(2):236-44.
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Sullivan WJ, Dixon SE, Li C, Striepen B, Queener SF. IMP dehydrogenase from the protozoan parasite Toxoplasma gondii. Antimicrob Agents Chemother. 2005 Jun; 49(6):2172-9.
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