TATA Box
"TATA Box" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A conserved A-T rich sequence which is contained in promoters for RNA polymerase II. The segment is seven base pairs long and the nucleotides most commonly found are TATAAAA.
Descriptor ID |
D016385
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MeSH Number(s) |
G02.111.570.080.689.675.850 G05.360.080.689.675.850 G05.360.340.024.340.137.750.680.850
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Concept/Terms |
TATA Box- TATA Box
- Box, TATA
- Hogness Box
- Box, Hogness
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Below are MeSH descriptors whose meaning is more general than "TATA Box".
Below are MeSH descriptors whose meaning is more specific than "TATA Box".
This graph shows the total number of publications written about "TATA Box" by people in this website by year, and whether "TATA Box" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1995 | 0 | 1 | 1 | 1996 | 0 | 1 | 1 | 2001 | 0 | 1 | 1 | 2007 | 2 | 0 | 2 | 2012 | 0 | 1 | 1 | 2013 | 1 | 0 | 1 | 2015 | 0 | 1 | 1 | 2017 | 0 | 1 | 1 |
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Below are the most recent publications written about "TATA Box" by people in Profiles.
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Kugel JF, Goodrich JA. Finding the start site: redefining the human initiator element. Genes Dev. 2017 01 01; 31(1):1-2.
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Murakami K, Tsai KL, Kalisman N, Bushnell DA, Asturias FJ, Kornberg RD. Structure of an RNA polymerase II preinitiation complex. Proc Natl Acad Sci U S A. 2015 Nov 03; 112(44):13543-8.
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Blair RH, Goodrich JA, Kugel JF. Using FRET to monitor protein-induced DNA bending: the TBP-TATA complex as a model system. Methods Mol Biol. 2013; 977:203-15.
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Blair RH, Goodrich JA, Kugel JF. Single-molecule fluorescence resonance energy transfer shows uniformity in TATA binding protein-induced DNA bending and heterogeneity in bending kinetics. Biochemistry. 2012 Sep 25; 51(38):7444-55.
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Hieb AR, Halsey WA, Betterton MD, Perkins TT, Kugel JF, Goodrich JA. TFIIA changes the conformation of the DNA in TBP/TATA complexes and increases their kinetic stability. J Mol Biol. 2007 Sep 21; 372(3):619-32.
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Weaver JR, Good K, Walters RD, Kugel JF, Goodrich JA. Characterization of the sequence and architectural constraints of the regulatory and core regions of the human interleukin-2 promoter. Mol Immunol. 2007 Apr; 44(11):2813-9.
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Conkright MD, Guzm?n E, Flechner L, Su AI, Hogenesch JB, Montminy M. Genome-wide analysis of CREB target genes reveals a core promoter requirement for cAMP responsiveness. Mol Cell. 2003 Apr; 11(4):1101-8.
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Ananthanarayanan M, Balasubramanian N, Makishima M, Mangelsdorf DJ, Suchy FJ. Human bile salt export pump promoter is transactivated by the farnesoid X receptor/bile acid receptor. J Biol Chem. 2001 Aug 03; 276(31):28857-65.
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Kosa PF, Ghosh G, DeDecker BS, Sigler PB. The 2.1-A crystal structure of an archaeal preinitiation complex: TATA-box-binding protein/transcription factor (II)B core/TATA-box. Proc Natl Acad Sci U S A. 1997 Jun 10; 94(12):6042-7.
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DeDecker BS, O'Brien R, Fleming PJ, Geiger JH, Jackson SP, Sigler PB. The crystal structure of a hyperthermophilic archaeal TATA-box binding protein. J Mol Biol. 1996 Dec 20; 264(5):1072-84.
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