Cantharidin
"Cantharidin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A toxic compound, isolated from the Spanish fly or blistering beetle (Lytta (Cantharis) vesicatoria) and other insects. It is a potent and specific inhibitor of protein phosphatases 1 (PP1) and 2A (PP2A). This compound can produce severe skin inflammation, and is extremely toxic if ingested orally.
| Descriptor ID |
D002193
|
| MeSH Number(s) |
D03.633.100.127.125
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Cantharidin".
Below are MeSH descriptors whose meaning is more specific than "Cantharidin".
This graph shows the total number of publications written about "Cantharidin" by people in this website by year, and whether "Cantharidin" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 1 | 0 | 1 |
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Below are the most recent publications written about "Cantharidin" by people in Profiles.
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Heyden A, L?tzow-Holm C, Clausen OP, Thrane EV, Brandtzaeg P, Roop DR, Yuspa SH, Huitfeldt HS. Application of cantharidin or 12-O-tetradecanoylphorbol-13-acetate on mouse epidermis induces a cell population shift that causes altered keratin distribution. Differentiation. 1994 Sep; 57(3):187-93.