 Prostatic Intraepithelial Neoplasia
"Prostatic Intraepithelial Neoplasia" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A premalignant change arising in the prostatic epithelium, regarded as the most important and most likely precursor of prostatic adenocarcinoma. The neoplasia takes the form of an intra-acinar or ductal proliferation of secretory cells with unequivocal nuclear anaplasia, which corresponds to nuclear grade 2 and 3 invasive prostate cancer.
| Descriptor ID |
D019048
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| MeSH Number(s) |
C04.557.470.200.240.500
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| Concept/Terms |
Prostatic Intraepithelial Neoplasia- Prostatic Intraepithelial Neoplasia
- Neoplasia, Prostatic Intraepithelial
- Intraepithelial Neoplasia, Prostatic
- Prostatic Intraepithelial Neoplasias
- Prostatic Intraepithelial Neoplasms
- Intraepithelial Neoplasm, Prostatic
- Intraepithelial Neoplasms, Prostatic
- Neoplasm, Prostatic Intraepithelial
- Neoplasms, Prostatic Intraepithelial
- Prostatic Intraepithelial Neoplasm
- Intraepithelial Prostatic Neoplasia
- Intraepithelial Prostatic Neoplasias
- Neoplasia, Intraepithelial Prostatic
- Prostatic Neoplasia, Intraepithelial
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Below are MeSH descriptors whose meaning is more general than "Prostatic Intraepithelial Neoplasia".
Below are MeSH descriptors whose meaning is more specific than "Prostatic Intraepithelial Neoplasia".
This graph shows the total number of publications written about "Prostatic Intraepithelial Neoplasia" by people in this website by year, and whether "Prostatic Intraepithelial Neoplasia" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 0 | 1 | 1 | | 2002 | 1 | 0 | 1 | | 2004 | 0 | 1 | 1 | | 2006 | 1 | 0 | 1 | | 2007 | 2 | 0 | 2 | | 2008 | 0 | 2 | 2 | | 2013 | 1 | 0 | 1 | | 2014 | 0 | 1 | 1 |
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Below are the most recent publications written about "Prostatic Intraepithelial Neoplasia" by people in Profiles.
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Iczkowski KA, Egevad L, Ma J, Harding-Jackson N, Algaba F, Billis A, Camparo P, Cheng L, Clouston D, Comperat EM, Datta MW, Evans AG, Griffiths DF, Guo CC, Hailemariam S, Huang W, Humphrey PA, Jiang Z, Kahane H, Kristiansen G, La Rosa FG, Lopez-Beltran A, MacLennan GT, Magi-Galluzzi C, Merrimen J, Montironi R, Osunkoya AO, Picken MM, Rao N, Shah RB, Shanks JH, Shen SS, Tawfik OW, True LD, Van der Kwast T, Varma M, Wheeler TM, Zynger DL, Sahr N, Bostwick DG. Intraductal carcinoma of the prostate: interobserver reproducibility survey of 39 urologic pathologists. Ann Diagn Pathol. 2014 Dec; 18(6):333-42.
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Iczkowski KA, Torkko KC, Wilson RS, Lucia MS, Bostwick DG. Prostatic atrophy: its spatial proximity to carcinoma and intraepithelial neoplasia based on annotation of digital slides. Hum Pathol. 2014 Jan; 45(1):54-8.
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Marshall JR, Tangen CM, Sakr WA, Wood DP, Berry DL, Klein EA, Lippman SM, Parnes HL, Alberts DS, Jarrard DF, Lee WR, Gaziano JM, Crawford ED, Ely B, Ray M, Davis W, Minasian LM, Thompson IM. Phase III trial of selenium to prevent prostate cancer in men with high-grade prostatic intraepithelial neoplasia: SWOG S9917. Cancer Prev Res (Phila). 2011 Nov; 4(11):1761-9.
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Varambally S, Laxman B, Mehra R, Cao Q, Dhanasekaran SM, Tomlins SA, Granger J, Vellaichamy A, Sreekumar A, Yu J, Gu W, Shen R, Ghosh D, Wright LM, Kladney RD, Kuefer R, Rubin MA, Fimmel CJ, Chinnaiyan AM. Golgi protein GOLM1 is a tissue and urine biomarker of prostate cancer. Neoplasia. 2008 Nov; 10(11):1285-94.
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Raina K, Rajamanickam S, Singh RP, Deep G, Chittezhath M, Agarwal R. Stage-specific inhibitory effects and associated mechanisms of silibinin on tumor progression and metastasis in transgenic adenocarcinoma of the mouse prostate model. Cancer Res. 2008 Aug 15; 68(16):6822-30.
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Gurel B, Iwata T, Koh CM, Jenkins RB, Lan F, Van Dang C, Hicks JL, Morgan J, Cornish TC, Sutcliffe S, Isaacs WB, Luo J, De Marzo AM. Nuclear MYC protein overexpression is an early alteration in human prostate carcinogenesis. Mod Pathol. 2008 Sep; 21(9):1156-67.
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Kim JH, Dhanasekaran SM, Mehra R, Tomlins SA, Gu W, Yu J, Kumar-Sinha C, Cao X, Dash A, Wang L, Ghosh D, Shedden K, Montie JE, Rubin MA, Pienta KJ, Shah RB, Chinnaiyan AM. Integrative analysis of genomic aberrations associated with prostate cancer progression. Cancer Res. 2007 Sep 01; 67(17):8229-39.
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Thompson IM, Lucia MS, Redman MW, Darke A, La Rosa FG, Parnes HL, Lippman SM, Coltman CA. Finasteride decreases the risk of prostatic intraepithelial neoplasia. J Urol. 2007 Jul; 178(1):107-9; discussion 110.
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Marshall JR, Sakr W, Wood D, Berry D, Tangen C, Parker F, Thompson I, Lippman SM, Lieberman R, Alberts D, Jarrard D, Coltman C, Greenwald P, Minasian L, Crawford ED. Design and progress of a trial of selenium to prevent prostate cancer among men with high-grade prostatic intraepithelial neoplasia. Cancer Epidemiol Biomarkers Prev. 2006 Aug; 15(8):1479-84.
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White KA, Lange EM, Ray AM, Wojno KJ, Cooney KA. Prohibitin mutations are uncommon in prostate cancer families linked to chromosome 17q. Prostate Cancer Prostatic Dis. 2006; 9(3):298-302.
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