Leukemia Inhibitory Factor Receptor alpha Subunit
"Leukemia Inhibitory Factor Receptor alpha Subunit" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A receptor subunit that combines with CYTOKINE RECEPTOR GP130 to form the dual specificity receptor for LEUKEMIA INHIBITORY FACTOR and ONCOSTATIN M. The subunit is also a component of the CILIARY NEUROTROPHIC FACTOR RECEPTOR. Both membrane-bound and secreted isoforms of the receptor subunit exist due to ALTERNATIVE SPLICING of its mRNA. The secreted isoform is believed to act as an inhibitory receptor, while the membrane-bound form is a signaling receptor.
| Descriptor ID |
D053680
|
| MeSH Number(s) |
D12.776.543.750.705.852.583.750 D12.776.543.750.750.400.550.250.750
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Leukemia Inhibitory Factor Receptor alpha Subunit".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Membrane Proteins [D12.776.543]
- Receptors, Cell Surface [D12.776.543.750]
- Receptors, Immunologic [D12.776.543.750.705]
- Receptors, Cytokine [D12.776.543.750.705.852]
- Receptors, OSM-LIF [D12.776.543.750.705.852.583]
- Leukemia Inhibitory Factor Receptor alpha Subunit [D12.776.543.750.705.852.583.750]
- Receptors, Peptide [D12.776.543.750.750]
- Receptors, Growth Factor [D12.776.543.750.750.400]
- Receptors, Nerve Growth Factor [D12.776.543.750.750.400.550]
- Receptor, Ciliary Neurotrophic Factor [D12.776.543.750.750.400.550.250]
- Leukemia Inhibitory Factor Receptor alpha Subunit [D12.776.543.750.750.400.550.250.750]
Below are MeSH descriptors whose meaning is more specific than "Leukemia Inhibitory Factor Receptor alpha Subunit".
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Below are the most recent publications written about "Leukemia Inhibitory Factor Receptor alpha Subunit" by people in Profiles.