Laccase
"Laccase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A copper-containing oxidoreductase enzyme that catalyzes the oxidation of 4-benzenediol to 4-benzosemiquinone. It also has activity towards a variety of O-quinols and P-quinols. It primarily found in FUNGI and is involved in LIGNIN degradation, pigment biosynthesis and detoxification of lignin-derived products.
Descriptor ID |
D042845
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MeSH Number(s) |
D08.811.682.494
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Concept/Terms |
Laccase- Laccase
- Urishiol Oxidase
- Oxidase, Urishiol
- p-Diphenol Oxidase
- Oxidase, p-Diphenol
- p Diphenol Oxidase
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Below are MeSH descriptors whose meaning is more general than "Laccase".
Below are MeSH descriptors whose meaning is more specific than "Laccase".
This graph shows the total number of publications written about "Laccase" by people in this website by year, and whether "Laccase" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1998 | 0 | 1 | 1 | 1999 | 0 | 1 | 1 | 2001 | 0 | 1 | 1 | 2002 | 0 | 1 | 1 | 2003 | 1 | 0 | 1 | 2005 | 1 | 0 | 1 |
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Below are the most recent publications written about "Laccase" by people in Profiles.
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Quintanar L, Yoon J, Aznar CP, Palmer AE, Andersson KK, Britt RD, Solomon EI. Spectroscopic and electronic structure studies of the trinuclear Cu cluster active site of the multicopper oxidase laccase: nature of its coordination unsaturation. J Am Chem Soc. 2005 Oct 12; 127(40):13832-45.
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Palmer AE, Szilagyi RK, Cherry JR, Jones A, Xu F, Solomon EI. Spectroscopic characterization of the Leu513His variant of fungal laccase: effect of increased axial ligand interaction on the geometric and electronic structure of the type 1 Cu site. Inorg Chem. 2003 Jun 30; 42(13):4006-17.
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Andersson KK, Schmidt PP, Katterle B, Strand KR, Palmer AE, Lee SK, Solomon EI, Gr?slund A, Barra AL. Examples of high-frequency EPR studies in bioinorganic chemistry. J Biol Inorg Chem. 2003 Feb; 8(3):235-47.
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Palmer AE, Lee SK, Solomon EI. Decay of the peroxide intermediate in laccase: reductive cleavage of the O-O bond. J Am Chem Soc. 2001 Jul 11; 123(27):6591-9.
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Xu F, Palmer AE, Yaver DS, Berka RM, Gambetta GA, Brown SH, Solomon EI. Targeted mutations in a Trametes villosa laccase. Axial perturbations of the T1 copper. J Biol Chem. 1999 Apr 30; 274(18):12372-5.
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Xu F, Berka RM, Wahleithner JA, Nelson BA, Shuster JR, Brown SH, Palmer AE, Solomon EI. Site-directed mutations in fungal laccase: effect on redox potential, activity and pH profile. Biochem J. 1998 Aug 15; 334 ( Pt 1):63-70.
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