 Trimethoprim
"Trimethoprim" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A pyrimidine inhibitor of dihydrofolate reductase, it is an antibacterial related to PYRIMETHAMINE. It is potentiated by SULFONAMIDES and the TRIMETHOPRIM, SULFAMETHOXAZOLE DRUG COMBINATION is the form most often used. It is sometimes used alone as an antimalarial. TRIMETHOPRIM RESISTANCE has been reported.
| Descriptor ID |
D014295
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| MeSH Number(s) |
D03.383.742.906
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Trimethoprim".
Below are MeSH descriptors whose meaning is more specific than "Trimethoprim".
This graph shows the total number of publications written about "Trimethoprim" by people in this website by year, and whether "Trimethoprim" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 1 | 0 | 1 | | 2012 | 0 | 1 | 1 |
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Below are the most recent publications written about "Trimethoprim" by people in Profiles.
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Rijnders B, DiSciullo GJ, Csiky B, Rutkowski B, Appelt K, Cheronis J, Aitchison R, Gordon G, Jadoul M, Fluck R. Locking Hemodialysis Catheters With Trimethoprim-Ethanol-Ca-EDTA to Prevent Bloodstream Infections: A Randomized, Evaluator-blinded Clinical Trial. Clin Infect Dis. 2019 06 18; 69(1):130-136.
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Shoulders MD, Ryno LM, Genereux JC, Moresco JJ, Tu PG, Wu C, Yates JR, Su AI, Kelly JW, Wiseman RL. Stress-independent activation of XBP1s and/or ATF6 reveals three functionally diverse ER proteostasis environments. Cell Rep. 2013 Apr 25; 3(4):1279-92.
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Hara N, Alkanani AK, Ir D, Robertson CE, Wagner BD, Frank DN, Zipris D. Prevention of virus-induced type 1 diabetes with antibiotic therapy. J Immunol. 2012 Oct 15; 189(8):3805-14.
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Brown PD, Freeman A, Foxman B. Prevalence and predictors of trimethoprim-sulfamethoxazole resistance among uropathogenic Escherichia coli isolates in Michigan. Clin Infect Dis. 2002 Apr 15; 34(8):1061-6.
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Twedt DC, Diehl KJ, Lappin MR, Getzy DM. Association of hepatic necrosis with trimethoprim sulfonamide administration in 4 dogs. J Vet Intern Med. 1997 Jan-Feb; 11(1):20-3.
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Enzenauer RW, Cornell FM, Brooke JD, Butler CE. Nocardia asteroides keratitis: a case associated with soft contact lens wear. CLAO J. 1989 Jan-Mar; 15(1):71-3.
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Roe MH, Tolliver PR, Lewis PL, Todd JK. Primary plate identification of group A Streptococcus on a selective medium. Efficiency in an office practice. Am J Dis Child. 1984 Jun; 138(6):589-91.
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Rodr?guez W, Delucchi C, Bidegain MA, Rodr?guez MS, Gleisner A, Figueroa S. [Treatment of urinary tract infections in children with trimethoprim-sulfamethoxypyridazine]. Rev Chil Pediatr. 1983 Nov-Dec; 54(6):402-6.
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Daum RS, Glode MP. Rifampin prophylaxis against H. flu type b spread - is it valid? Hosp Pract (Off Ed). 1982 Nov; 17(11):124A-C, 124K-L, 124N-P.
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