Hemangioma, Cavernous, Central Nervous System
"Hemangioma, Cavernous, Central Nervous System" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A vascular anomaly composed of a collection of large, thin walled tortuous VEINS that can occur in any part of the central nervous system but lack intervening nervous tissue. Familial occurrence is common and has been associated with a number of genes mapped to 7q, 7p and 3q. Clinical features include SEIZURES; HEADACHE; STROKE; and progressive neurological deficit.
Descriptor ID |
D020786
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MeSH Number(s) |
C04.557.645.375.385.500 C10.500.190.200 C14.240.850.875.249 C14.907.454.385.500 C15.378.463.515.385.500 C16.131.666.190.200
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Concept/Terms |
Cerebral Cavernous Hemangioma- Cerebral Cavernous Hemangioma
- Cavernous Hemangioma, Cerebral
- Cavernous Hemangiomas, Cerebral
- Cerebral Cavernous Hemangiomas
- Hemangioma, Cerebral Cavernous
- Hemangiomas, Cerebral Cavernous
Cavernous Hemangioma, Extracerebral- Cavernous Hemangioma, Extracerebral
- Cavernous Hemangiomas, Extracerebral
- Extracerebral Cavernous Hemangioma
- Extracerebral Cavernous Hemangiomas
- Hemangioma, Extracerebral Cavernous
- Hemangiomas, Extracerebral Cavernous
Cavernous Hemangioma, Intracerebral- Cavernous Hemangioma, Intracerebral
- Cavernous Hemangiomas, Intracerebral
- Hemangioma, Intracerebral Cavernous
- Hemangiomas, Intracerebral Cavernous
- Intracerebral Cavernous Hemangiomas
- Intracerebral Cavernous Hemangioma
Cavernous Hemangioma of Brain- Cavernous Hemangioma of Brain
- Brain Cavernous Hemangioma
- Brain Cavernous Hemangiomas
- Cavernous Angiomatous Malformations
- Angiomatous Malformation, Cavernous
- Angiomatous Malformations, Cavernous
- Cavernous Angiomatous Malformation
- Malformation, Cavernous Angiomatous
- Malformations, Cavernous Angiomatous
- Familial Cavernous Malformation
- Cavernous Malformation, Familial
- Cavernous Malformations, Familial
- Familial Cavernous Malformations
- Malformation, Familial Cavernous
- Malformations, Familial Cavernous
- Cerebral Cavernous Malformation
- Cavernous Malformation, Cerebral
- Cavernous Malformations, Cerebral
- Malformation, Cerebral Cavernous
- Malformations, Cerebral Cavernous
- Cerebral Cavernous Malformations
- Cavernous Angioma, Familial
- Angioma, Familial Cavernous
- Angiomas, Familial Cavernous
- Cavernous Angiomas, Familial
- Familial Cavernous Angioma
- Familial Cavernous Angiomas
- Cerebral Capillary Malformations
- Capillary Malformation, Cerebral
- Capillary Malformations, Cerebral
- Cerebral Capillary Malformation
- Malformation, Cerebral Capillary
- Malformations, Cerebral Capillary
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Below are MeSH descriptors whose meaning is more general than "Hemangioma, Cavernous, Central Nervous System".
- Diseases [C]
- Neoplasms [C04]
- Neoplasms by Histologic Type [C04.557]
- Neoplasms, Vascular Tissue [C04.557.645]
- Hemangioma [C04.557.645.375]
- Hemangioma, Cavernous [C04.557.645.375.385]
- Hemangioma, Cavernous, Central Nervous System [C04.557.645.375.385.500]
- Nervous System Diseases [C10]
- Nervous System Malformations [C10.500]
- Central Nervous System Vascular Malformations [C10.500.190]
- Hemangioma, Cavernous, Central Nervous System [C10.500.190.200]
- Cardiovascular Diseases [C14]
- Cardiovascular Abnormalities [C14.240]
- Vascular Malformations [C14.240.850]
- Central Nervous System Vascular Malformations [C14.240.850.875]
- Hemangioma, Cavernous, Central Nervous System [C14.240.850.875.249]
- Vascular Diseases [C14.907]
- Hemostatic Disorders [C14.907.454]
- Hemangioma, Cavernous [C14.907.454.385]
- Hemangioma, Cavernous, Central Nervous System [C14.907.454.385.500]
- Hemic and Lymphatic Diseases [C15]
- Hematologic Diseases [C15.378]
- Hemorrhagic Disorders [C15.378.463]
- Hemostatic Disorders [C15.378.463.515]
- Hemangioma, Cavernous [C15.378.463.515.385]
- Hemangioma, Cavernous, Central Nervous System [C15.378.463.515.385.500]
- Congenital, Hereditary, and Neonatal Diseases and Abnormalities [C16]
- Congenital Abnormalities [C16.131]
- Nervous System Malformations [C16.131.666]
- Central Nervous System Vascular Malformations [C16.131.666.190]
- Hemangioma, Cavernous, Central Nervous System [C16.131.666.190.200]
Below are MeSH descriptors whose meaning is more specific than "Hemangioma, Cavernous, Central Nervous System".
This graph shows the total number of publications written about "Hemangioma, Cavernous, Central Nervous System" by people in this website by year, and whether "Hemangioma, Cavernous, Central Nervous System" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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2001 | 1 | 0 | 1 | 2003 | 1 | 0 | 1 | 2004 | 1 | 1 | 2 | 2005 | 1 | 0 | 1 | 2006 | 1 | 0 | 1 | 2017 | 1 | 0 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "Hemangioma, Cavernous, Central Nervous System" by people in Profiles.
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Schwefel K, Spiegler S, Much CD, Felbor U, Rath M. CRISPR/Cas9-mediated Generation of Human Endothelial Cell Knockout Models of CCM Disease. Methods Mol Biol. 2020; 2152:169-177.
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Spiegler S, Rath M, Much CD, Sendtner BS, Felbor U. Precise CCM1 gene correction and inactivation in patient-derived endothelial cells: Modeling Knudson's two-hit hypothesis in vitro. Mol Genet Genomic Med. 2019 07; 7(7):e00755.
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Labowsky MT, Walter SD, McDonald MT, Mruthyunjaya P. Neuro-oculo-cutaneous cavernous hemangiomas: a CCM1 mutation-associated phakomatosis. J AAPOS. 2017 Oct; 21(5):426-429.e1.
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Hoes K, Hatanpaa K, Raisanen J, Gluf W. Epidural spinal cavernous hemangioma and hybrid vascular subtype. Clin Neuropathol. 2016 Nov/Dec; 35(6):368-374.
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Girard R, Khanna O, Shenkar R, Zhang L, Wu M, Jesselson M, Zeineddine HA, Gangal A, Fam MD, Gibson CC, Whitehead KJ, Li DY, Liao JK, Shi C, Awad IA. Peripheral plasma vitamin D and non-HDL cholesterol reflect the severity of cerebral cavernous malformation disease. Biomark Med. 2016; 10(3):255-64.
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Mikati AG, Khanna O, Zhang L, Girard R, Shenkar R, Guo X, Shah A, Larsson HB, Tan H, Li L, Wishnoff MS, Shi C, Christoforidis GA, Awad IA. Vascular permeability in cerebral cavernous malformations. J Cereb Blood Flow Metab. 2015 Oct; 35(10):1632-9.
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Lee JY, Ramakrishnan VR, Chiu AG, Palmer J, Gausas RE. Endoscopic endonasal surgical resection of tumors of the medial orbital apex and wall. Clin Neurol Neurosurg. 2012 Jan; 114(1):93-8.
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Bhatia S, O'Neill BR, Pu F, Aziz K. Giant tentorial cavernous hemangioma: case report and review of literature. Clin Neurol Neurosurg. 2011 Dec; 113(10):937-42.
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El-Koussy M, Stepper F, Spreng A, Lukes A, Gralla J, Brekenfeld C, Sturzenegger M, Schroth G. Incidence, clinical presentation and imaging findings of cavernous malformations of the CNS. A twenty-year experience. Swiss Med Wkly. 2011; 141:w13172.
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Gault J, Sain S, Hu LJ, Awad IA. Spectrum of genotype and clinical manifestations in cerebral cavernous malformations. Neurosurgery. 2006 Dec; 59(6):1278-84; discussion 1284-5.
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