 Deoxyribonucleases, Type I Site-Specific
"Deoxyribonucleases, Type I Site-Specific" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Enzyme systems containing three different subunits and requiring ATP, S-adenosylmethionine, and magnesium for endonucleolytic activity to give random double-stranded fragments with terminal 5'-phosphates. They function also as DNA-dependent ATPases and modification methylases, catalyzing the reactions of EC 2.1.1.72 and EC 2.1.1.73 with similar site-specificity. The systems recognize specific short DNA sequences and cleave at sites remote from the recognition sequence. Enzymes from different microorganisms with the same specificity are called isoschizomers. EC 3.1.21.3.
| Descriptor ID |
D015253
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| MeSH Number(s) |
D08.811.150.280.250 D08.811.277.352.335.350.300.250 D08.811.277.352.355.325.300.250
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| Concept/Terms |
Deoxyribonucleases, Type I Site-Specific- Deoxyribonucleases, Type I Site-Specific
- Deoxyribonucleases, Type I Site Specific
- Deoxyribonucleases, Type I, Site-Specific
- Type I Site Specific Deoxyribonucleases
- Type I Site-Specific Deoxyribonucleases
- DNA Restriction Enzymes, Type I
- Type I Restriction Enzymes
- Site-Specific DNase, Type I
- Site Specific DNase, Type I
- Type I Site Specific DNase
- Type I Site-Specific DNase
- DNase, Site-Specific, Type I
- Restriction Endonucleases, Type I
- Deoxyribonucleases, Type I, Site Specific
- DNase, Site Specific, Type I
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