Ventral striatal blood flow is altered by acute nicotine but not withdrawal from nicotine.
Tanabe J, Crowley T, Hutchison K, Miller D, Johnson G, Du YP, Zerbe G, Freedman R. Ventral striatal blood flow is altered by acute nicotine but not withdrawal from nicotine. Neuropsychopharmacology. 2008 Feb; 33(3):627-33.