Colorado PROFILES, The Colorado Clinical and Translational Sciences Institute (CCTSI)
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This is a "connection" page, showing publications co-authored by Maggie Lam and Edward Lau.

 
Connection Strength
 
 
 
7.317
 
  1. Lau E, Han Y, Williams DR, Thomas CT, Shrestha R, Wu JC, Lam MPY. Splice-Junction-Based Mapping of Alternative Isoforms in the Human Proteome. Cell Rep. 2019 12 10; 29(11):3751-3765.e5.
    View in: PubMed
    Score: 0.663
  2. Lau E, Venkatraman V, Thomas CT, Wu JC, Van Eyk JE, Lam MPY. Identifying High-Priority Proteins Across the Human Diseasome Using Semantic Similarity. J Proteome Res. 2018 12 07; 17(12):4267-4278.
    View in: PubMed
    Score: 0.612
  3. Han Y, Binti S, Wennersten SA, Pandi B, Ng DC, Lau E, Lam MP. A ratiometric catalog of protein isoform shifts in the cardiac fetal gene program. JCI Insight. 2025 Sep 23; 10(18).
    View in: PubMed
    Score: 0.246
  4. Alamillo L, Black A, Lam MPY, Lau E. Protein Turnover Dynamics Analysis With Subcellular Spatial Resolution. Bio Protoc. 2025 Aug 05; 15(15):e5409.
    View in: PubMed
    Score: 0.245
  5. Alamillo L, Ng DCM, Currie J, Black A, Pandi B, Manda V, Pavelka J, Schaal P, Travers JG, McKinsey TA, Lam MPY, Lau E. Deuterium labeling enables proteome-wide turnover kinetics analysis in cell culture. Cell Rep Methods. 2025 Jul 21; 5(7):101104.
    View in: PubMed
    Score: 0.244
  6. Han Y, Binti S, Wennersten SA, Pandi B, Ng DCM, Lau E, Lam MPY. A Ratiometric Catalog of Protein Isoform Shifts in the Cardiac Fetal Gene Program. bioRxiv. 2025 May 31.
    View in: PubMed
    Score: 0.242
  7. Currie J, Ng DCM, Pandi B, Black A, Manda V, Durham C, Pavelka J, Lam MPY, Lau E. Improved Method to Determine Protein Turnover Rates with Heavy Water Labeling by Mass Isotopomer Ratio Selection. J Proteome Res. 2025 Apr 04; 24(4):1992-2005.
    View in: PubMed
    Score: 0.239
  8. Alamillo L, Ng DCM, Currie J, Black A, Pandi B, Manda V, Pavelka J, Schaal P, Travers JG, McKinsey TA, Lam MPY, Lau E. Deuterium labeling enables proteome wide turnover kinetics analysis in cell culture. bioRxiv. 2025 Jan 31.
    View in: PubMed
    Score: 0.237
  9. Currie J, Ng DCM, Pandi B, Black A, Manda V, Pavelka J, Lam MPY, Lau E. Improved determination of protein turnover rate with heavy water labeling by mass isotopomer ratio selection. bioRxiv. 2024 Jun 04.
    View in: PubMed
    Score: 0.226
  10. Currie J, Manda V, Robinson SK, Lai C, Agnihotri V, Hidalgo V, Ludwig RW, Zhang K, Pavelka J, Wang ZV, Rhee JW, Lam MPY, Lau E. Simultaneous proteome localization and turnover analysis reveals spatiotemporal features of protein homeostasis disruptions. Nat Commun. 2024 Mar 11; 15(1):2207.
    View in: PubMed
    Score: 0.223
  11. Pandi B, Brenman S, Black A, Ng DCM, Lau E, Lam MPY. Tissue Usage Preference and Intrinsically Disordered Region Remodeling of Alternative Splicing Derived Proteoforms in the Heart. J Proteome Res. 2024 08 02; 23(8):3161-3173.
    View in: PubMed
    Score: 0.223
  12. Currie J, Manda V, Robinson SK, Lai C, Agnihotri V, Hidalgo V, Ludwig RW, Zhang K, Pavelka J, Wang ZV, Rhee JW, Lam MPY, Lau E. Simultaneous proteome localization and turnover analysis reveals spatiotemporal features of protein homeostasis disruptions. bioRxiv. 2024 Jan 17.
    View in: PubMed
    Score: 0.220
  13. Pandi B, Brenman S, Black A, Ng DCM, Lau E, Lam MPY. Tissue Usage Preference and Intrinsically Disordered Region Remodeling of Alternative Splicing Derived Proteoforms in the Heart. bioRxiv. 2023 Oct 09.
    View in: PubMed
    Score: 0.216
  14. Kastury N, Hidalgo V, Pandi B, Li L, Lam MPY, Lau E. Senescence in human AC16 cardiac cells is associated with thymidine kinase induction and histone loss. MicroPubl Biol. 2023; 2023.
    View in: PubMed
    Score: 0.212
  15. Hidalgo V, Kastury N, Durham CW, Currie J, Amaya M, Lam MPY, Lau E. Co-culture with normal and senescent AC16 cardiomyocytes modulates fibrotic response in primary human ventricular fibroblasts. MicroPubl Biol. 2023; 2023.
    View in: PubMed
    Score: 0.212
  16. Srivastava H, Lippincott MJ, Currie J, Canfield R, Lam MPY, Lau E. Protein prediction models support widespread post-transcriptional regulation of protein abundance by interacting partners. PLoS Comput Biol. 2022 11; 18(11):e1010702.
    View in: PubMed
    Score: 0.203
  17. Han Y, Wennersten SA, Wright JM, Ludwig RW, Lau E, Lam MPY. Proteogenomics reveals sex-biased aging genes and coordinated splicing in cardiac aging. Am J Physiol Heart Circ Physiol. 2022 09 01; 323(3):H538-H558.
    View in: PubMed
    Score: 0.199
  18. Han Y, Thomas CT, Wennersten SA, Lau E, Lam MPY. Shotgun Proteomics Sample Processing Automated by an Open-Source Lab Robot. J Vis Exp. 2021 10 28; (176).
    View in: PubMed
    Score: 0.189
  19. Han Y, Li LZ, Kastury NL, Thomas CT, Lam MPY, Lau E. Transcriptome features of striated muscle aging and predictability of protein level changes. Mol Omics. 2021 10 11; 17(5):796-808.
    View in: PubMed
    Score: 0.188
  20. Han Y, Wood SD, Wright JM, Dostal V, Lau E, Lam MPY. Computation-assisted targeted proteomics of alternative splicing protein isoforms in the human heart. J Mol Cell Cardiol. 2021 05; 154:92-96.
    View in: PubMed
    Score: 0.180
  21. Dostal V, Wood SD, Thomas CT, Han Y, Lau E, Lam MPY. Proteomic signatures of acute oxidative stress response to paraquat in the mouse heart. Sci Rep. 2020 10 28; 10(1):18440.
    View in: PubMed
    Score: 0.176
  22. Lau E, Cao Q, Lam MPY, Wang J, Ng DCM, Bleakley BJ, Lee JM, Liem DA, Wang D, Hermjakob H, Ping P. Integrated omics dissection of proteome dynamics during cardiac remodeling. Nat Commun. 2018 01 09; 9(1):120.
    View in: PubMed
    Score: 0.145
  23. Lam MP, Lau E, Ng DC, Wang D, Ping P. Cardiovascular proteomics in the era of big data: experimental and computational advances. Clin Proteomics. 2016; 13:23.
    View in: PubMed
    Score: 0.135
  24. Lam MP, Venkatraman V, Xing Y, Lau E, Cao Q, Ng DC, Su AI, Ge J, Van Eyk JE, Ping P. Data-Driven Approach To Determine Popular Proteins for Targeted Proteomics Translation of Six Organ Systems. J Proteome Res. 2016 11 04; 15(11):4126-4134.
    View in: PubMed
    Score: 0.131
  25. Lau E, Cao Q, Ng DC, Bleakley BJ, Dincer TU, Bot BM, Wang D, Liem DA, Lam MP, Ge J, Ping P. A large dataset of protein dynamics in the mammalian heart proteome. Sci Data. 2016 Mar 15; 3:160015.
    View in: PubMed
    Score: 0.128
  26. Lam MP, Venkatraman V, Cao Q, Wang D, Dincer TU, Lau E, Su AI, Xing Y, Ge J, Ping P, Van Eyk JE. Prioritizing Proteomics Assay Development for Clinical Translation. J Am Coll Cardiol. 2015 Jul 14; 66(2):202-4.
    View in: PubMed
    Score: 0.122
  27. Lau E, Huang D, Cao Q, Dincer TU, Black CM, Lin AJ, Lee JM, Wang D, Liem DA, Lam MP, Ping P. Spatial and temporal dynamics of the cardiac mitochondrial proteome. Expert Rev Proteomics. 2015 Apr; 12(2):133-46.
    View in: PubMed
    Score: 0.119
  28. Zong N, Ping P, Lau E, Choi HJ, Ng DC, Meyer D, Fang C, Li H, Wang D, Zelaya IM, Yates JR, Lam MP. Lysine ubiquitination and acetylation of human cardiac 20S proteasomes. Proteomics Clin Appl. 2014 Aug; 8(7-8):590-594.
    View in: PubMed
    Score: 0.114
  29. Lam MP, Wang D, Lau E, Liem DA, Kim AK, Ng DC, Liang X, Bleakley BJ, Liu C, Tabaraki JD, Cadeiras M, Wang Y, Deng MC, Ping P. Protein kinetic signatures of the remodeling heart following isoproterenol stimulation. J Clin Invest. 2014 Apr; 124(4):1734-44.
    View in: PubMed
    Score: 0.111
  30. Lam MP, Lau E, Liem DA, Ping P. Cyclophilin D and acetylation: a new link in cardiac signaling. Circ Res. 2013 Dec 06; 113(12):1268-9.
    View in: PubMed
    Score: 0.109
  31. Lam MP, Lau E, Scruggs SB, Wang D, Kim TY, Liem DA, Zhang J, Ryan CM, Faull KF, Ping P. Site-specific quantitative analysis of cardiac mitochondrial protein phosphorylation. J Proteomics. 2013 Apr 09; 81:15-23.
    View in: PubMed
    Score: 0.101
  32. Lau E, Wang D, Zhang J, Yu H, Lam MP, Liang X, Zong N, Kim TY, Ping P. Substrate- and isoform-specific proteome stability in normal and stressed cardiac mitochondria. Circ Res. 2012 Apr 27; 110(9):1174-8.
    View in: PubMed
    Score: 0.097
  33. Lam MP, Scruggs SB, Kim TY, Zong C, Lau E, Wang D, Ryan CM, Faull KF, Ping P. An MRM-based workflow for quantifying cardiac mitochondrial protein phosphorylation in murine and human tissue. J Proteomics. 2012 Aug 03; 75(15):4602-9.
    View in: PubMed
    Score: 0.097
  34. Lam MP, Lau E, Siu SO, Ng DC, Kong RP, Chiu PC, Yeung WS, Lo C, Chu IK. Online combination of reversed-phase/reversed-phase and porous graphitic carbon liquid chromatography for multicomponent separation of proteomics and glycoproteomics samples. Electrophoresis. 2011 Nov; 32(21):2930-40.
    View in: PubMed
    Score: 0.094
  35. Lau E, Lam MP, Siu SO, Kong RP, Chan WL, Zhou Z, Huang J, Lo C, Chu IK. Combinatorial use of offline SCX and online RP-RP liquid chromatography for iTRAQ-based quantitative proteomics applications. Mol Biosyst. 2011 May; 7(5):1399-408.
    View in: PubMed
    Score: 0.090
  36. Lam MP, Siu SO, Lau E, Mao X, Sun HZ, Chiu PC, Yeung WS, Cox DM, Chu IK. Online coupling of reverse-phase and hydrophilic interaction liquid chromatography for protein and glycoprotein characterization. Anal Bioanal Chem. 2010 Sep; 398(2):791-804.
    View in: PubMed
    Score: 0.086
  37. Eaton DM, Berretta RM, Lynch JE, Travers JG, Pfeiffer RD, Hulke ML, Zhao H, Hobby ARH, Schena G, Johnson JP, Wallner M, Lau E, Lam MPY, Woulfe KC, Tucker NR, McKinsey TA, Wolfson MR, Houser SR. Sex-specific responses to slow progressive pressure overload in a large animal model of HFpEF. Am J Physiol Heart Circ Physiol. 2022 10 01; 323(4):H797-H817.
    View in: PubMed
    Score: 0.050
  38. Chour T, Tian L, Lau E, Thomas D, Itzhaki I, Malak O, Zhang JZ, Qin X, Wardak M, Liu Y, Chandy M, Black KE, Lam MP, Neofytou E, Wu JC. Method for selective ablation of undifferentiated human pluripotent stem cell populations for cell-based therapies. JCI Insight. 2021 04 08; 6(7).
    View in: PubMed
    Score: 0.045
  39. Wang D, Liem DA, Lau E, Ng DC, Bleakley BJ, Cadeiras M, Deng MC, Lam MP, Ping P. Characterization of human plasma proteome dynamics using deuterium oxide. Proteomics Clin Appl. 2014 Aug; 8(7-8):610-9.
    View in: PubMed
    Score: 0.029
  40. Kim TY, Wang D, Kim AK, Lau E, Lin AJ, Liem DA, Zhang J, Zong NC, Lam MP, Ping P. Metabolic labeling reveals proteome dynamics of mouse mitochondria. Mol Cell Proteomics. 2012 Dec; 11(12):1586-94.
    View in: PubMed
    Score: 0.025
  41. Zhang J, Lin A, Powers J, Lam MP, Lotz C, Liem D, Lau E, Wang D, Deng N, Korge P, Zong NC, Cai H, Weiss J, Ping P. Perspectives on: SGP symposium on mitochondrial physiology and medicine: mitochondrial proteome design: from molecular identity to pathophysiological regulation. J Gen Physiol. 2012 Jun; 139(6):395-406.
    View in: PubMed
    Score: 0.025
  42. Siu SO, Lam MP, Lau E, Kong RP, Lee SM, Chu IK. Fully automatable two-dimensional reversed-phase capillary liquid chromatography with online tandem mass spectrometry for shotgun proteomics. Proteomics. 2011 Jun; 11(11):2308-19.
    View in: PubMed
    Score: 0.023
  43. Liu H, Lau E, Lam MPY, Chu H, Li S, Huang G, Guo P, Wang J, Jiang L, Chu IK, Lo C, Tao Y. OsNOA1/RIF1 is a functional homolog of AtNOA1/RIF1: implication for a highly conserved plant cGTPase essential for chloroplast function. New Phytol. 2010 Jul; 187(1):83-105.
    View in: PubMed
    Score: 0.021
  44. Siu SO, Lam MP, Lau E, Yeung WS, Cox DM, Chu IK. N-linked glycoprotein analysis using dual-extraction ultrahigh-performance liquid chromatography and electrospray tandem mass spectrometry. Methods Mol Biol. 2010; 600:133-43.
    View in: PubMed
    Score: 0.021
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