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Connection

Lori Sussel to Humans

This is a "connection" page, showing publications Lori Sussel has written about Humans.

 
Connection Strength
 
 
 
0.491
 
  1. Bluestone JA, Herold KC, Sussel L. Type 1 Diabetes: Advances in Understanding and Treatment 100 Years after the Discovery of Insulin. Cold Spring Harb Perspect Med. 2026 05 01; 16(5).
    View in: PubMed
    Score: 0.024
  2. Hansen MS, Pokharel P, Piganelli J, Sussel L. The Chicken or the Egg Dilemma: Understanding the Interplay between the Immune System and the ß Cell in Type 1 Diabetes. Cold Spring Harb Perspect Med. 2025 04 01; 15(4).
    View in: PubMed
    Score: 0.022
  3. Schaaf C, Sussel L. A Cure for Type 1 Diabetes: Are We There Yet? Diabetes Technol Ther. 2025 06; 27(6):413-421.
    View in: PubMed
    Score: 0.022
  4. Kim YK, Won KC, Sussel L. Glucose metabolism partially regulates ß-cell function through epigenomic changes. J Diabetes Investig. 2024 Jun; 15(6):649-655.
    View in: PubMed
    Score: 0.020
  5. Kim YK, Kim YR, Wells KL, Sarbaugh D, Guney M, Tsai CF, Zee T, Karsenty G, Nakayasu ES, Sussel L. PTPN2 Regulates Metabolic Flux to Affect ß-Cell Susceptibility to Inflammatory Stress. Diabetes. 2024 Mar 01; 73(3):434-447.
    View in: PubMed
    Score: 0.020
  6. Brooks EP, Sussel L. Not the second fiddle: a cell development, identity, and function in health and diabetes. J Endocrinol. 2023 08 01; 258(2).
    View in: PubMed
    Score: 0.020
  7. Lorberbaum DS, Sarbaugh D, Sussel L. Leveraging the strengths of mice, human stem cells, and organoids to model pancreas development and diabetes. Front Endocrinol (Lausanne). 2022; 13:1042611.
    View in: PubMed
    Score: 0.019
  8. Russ HA, Shilleh AH, Sussel L. From the dish to humans: A stem cell recipe for success. Cell Metab. 2022 02 01; 34(2):193-196.
    View in: PubMed
    Score: 0.018
  9. Docherty FM, Sussel L. Islet Regeneration: Endogenous and Exogenous Approaches. Int J Mol Sci. 2021 Mar 24; 22(7).
    View in: PubMed
    Score: 0.017
  10. Lorberbaum DS, Kishore S, Rosselot C, Sarbaugh D, Brooks EP, Aragon E, Xuan S, Simon O, Ghosh D, Mendelsohn C, Gadue P, Sussel L. Retinoic acid signaling within pancreatic endocrine progenitors regulates mouse and human ß cell specification. Development. 2020 06 22; 147(12).
    View in: PubMed
    Score: 0.016
  11. Lorberbaum DS, Docherty FM, Sussel L. Animal Models of Pancreas Development, Developmental Disorders, and Disease. Adv Exp Med Biol. 2020; 1236:65-85.
    View in: PubMed
    Score: 0.015
  12. Singer RA, Arnes L, Cui Y, Wang J, Gao Y, Guney MA, Burnum-Johnson KE, Rabadan R, Ansong C, Orr G, Sussel L. The Long Noncoding RNA Paupar Modulates PAX6 Regulatory Activities to Promote Alpha Cell Development and Function. Cell Metab. 2019 12 03; 30(6):1091-1106.e8.
    View in: PubMed
    Score: 0.015
  13. Hudish LI, Reusch JE, Sussel L. ß Cell dysfunction during progression of metabolic syndrome to type 2 diabetes. J Clin Invest. 2019 10 01; 129(10):4001-4008.
    View in: PubMed
    Score: 0.015
  14. Romer AI, Singer RA, Sui L, Egli D, Sussel L. Murine Perinatal ß-Cell Proliferation and the Differentiation of Human Stem Cell-Derived Insulin-Expressing Cells Require NEUROD1. Diabetes. 2019 12; 68(12):2259-2271.
    View in: PubMed
    Score: 0.015
  15. Singer RA, Sussel L. Islet Long Noncoding RNAs: A Playbook for Discovery and Characterization. Diabetes. 2018 08; 67(8):1461-1470.
    View in: PubMed
    Score: 0.014
  16. Lorberbaum DS, Sussel L. Gotta Have GATA for Human Pancreas Development. Cell Stem Cell. 2017 05 04; 20(5):577-579.
    View in: PubMed
    Score: 0.013
  17. Gutiérrez GD, Bender AS, Cirulli V, Mastracci TL, Kelly SM, Tsirigos A, Kaestner KH, Sussel L. Pancreatic ß cell identity requires continual repression of non-ß cell programs. J Clin Invest. 2017 01 03; 127(1):244-259.
    View in: PubMed
    Score: 0.012
  18. Arnes L, Akerman I, Balderes DA, Ferrer J, Sussel L. ßlinc1 encodes a long noncoding RNA that regulates islet ß-cell formation and function. Genes Dev. 2016 Mar 01; 30(5):502-7.
    View in: PubMed
    Score: 0.012
  19. Borok MJ, Papaioannou VE, Sussel L. Unique functions of Gata4 in mouse liver induction and heart development. Dev Biol. 2016 Feb 15; 410(2):213-222.
    View in: PubMed
    Score: 0.012
  20. Romer AI, Sussel L. Pancreatic islet cell development and regeneration. Curr Opin Endocrinol Diabetes Obes. 2015 Aug; 22(4):255-64.
    View in: PubMed
    Score: 0.011
  21. Singer RA, Arnes L, Sussel L. Noncoding RNAs in ß cell biology. Curr Opin Endocrinol Diabetes Obes. 2015 Apr; 22(2):77-85.
    View in: PubMed
    Score: 0.011
  22. Arnes L, Sussel L. Epigenetic modifications and long noncoding RNAs influence pancreas development and function. Trends Genet. 2015 Jun; 31(6):290-9.
    View in: PubMed
    Score: 0.011
  23. Sussel L, Niswander L. Editorial overview: developmental mechanisms, patterning and evolution. Curr Opin Genet Dev. 2014 Aug; 27:v-vii.
    View in: PubMed
    Score: 0.010
  24. Mastracci TL, Anderson KR, Papizan JB, Sussel L. Regulation of Neurod1 contributes to the lineage potential of Neurogenin3+ endocrine precursor cells in the pancreas. PLoS Genet. 2013; 9(2):e1003278.
    View in: PubMed
    Score: 0.010
  25. Sussel L. Advances in pancreas development: generation informs regeneration. Semin Cell Dev Biol. 2012 Aug; 23(6):655.
    View in: PubMed
    Score: 0.009
  26. Mastracci TL, Sussel L. The endocrine pancreas: insights into development, differentiation, and diabetes. Wiley Interdiscip Rev Dev Biol. 2012 Sep-Oct; 1(5):609-28.
    View in: PubMed
    Score: 0.009
  27. Anderson KR, Singer RA, Balderes DA, Hernandez-Lagunas L, Johnson CW, Artinger KB, Sussel L. The L6 domain tetraspanin Tm4sf4 regulates endocrine pancreas differentiation and directed cell migration. Development. 2011 Aug; 138(15):3213-24.
    View in: PubMed
    Score: 0.009
  28. Hill JT, Chao CS, Anderson KR, Kaufman F, Johnson CW, Sussel L. Nkx2.2 activates the ghrelin promoter in pancreatic islet cells. Mol Endocrinol. 2010 Feb; 24(2):381-90.
    View in: PubMed
    Score: 0.008
  29. Jang S, Abarinov EV, Dobkin JA, Hurley EC, Closser M, Sussel L, Wichterle H. Independent control of neurogenesis and dorsoventral patterning by NKX2-2. Genes Dev. 2026 03 02; 40(5-6):384-395.
    View in: PubMed
    Score: 0.006
  30. Bandral M, Sussel L, Lorberbaum DS. Retinoid signaling in pancreas development, islet function, and disease. Curr Top Dev Biol. 2025; 161:297-318.
    View in: PubMed
    Score: 0.005
  31. Haemmerle MW, Scota AV, Khosravifar M, Varney MJ, Sen S, Good AL, Yang X, Wells KL, Sussel L, Rozo AV, Doliba NM, Ghanem LR, Stoffers DA. RNA-binding protein PCBP2 regulates pancreatic ß cell function and adaptation to glucose. J Clin Invest. 2024 Jun 17; 134(12).
    View in: PubMed
    Score: 0.005
  32. Doyle MJ, Sussel L. Engineering islets: lessons from stem cells and embryonic development. Endocrinol Metab Clin North Am. 2004 Mar; 33(1):149-62, x.
    View in: PubMed
    Score: 0.005
  33. Sarkar S, Deiter C, Kyle JE, Guney MA, Sarbaugh D, Yin R, Li X, Cui Y, Ramos-Rodriguez M, Nicora CD, Syed F, Juan-Mateu J, Muralidharan C, Pasquali L, Evans-Molina C, Eizirik DL, Webb-Robertson BM, Burnum-Johnson K, Orr G, Laskin J, Metz TO, Mirmira RG, Sussel L, Ansong C, Nakayasu ES. Regulation of ß-cell death by ADP-ribosylhydrolase ARH3 via lipid signaling in insulitis. Cell Commun Signal. 2024 02 21; 22(1):141.
    View in: PubMed
    Score: 0.005
  34. Putman MS, Norris AW, Hull RL, Rickels MR, Sussel L, Blackman SM, Chan CL, Ode KL, Daley T, Stecenko AA, Moran A, Helmick MJ, Cray S, Alvarez JA, Stallings VA, Tuggle KL, Clancy JP, Eggerman TL, Engelhardt JF, Kelly A. Cystic Fibrosis-Related Diabetes Workshop: Research Priorities Spanning Disease Pathophysiology, Diagnosis, and Outcomes. Diabetes. 2023 06 01; 72(6):677-689.
    View in: PubMed
    Score: 0.005
  35. Putman MS, Norris AW, Hull RL, Rickels MR, Sussel L, Blackman SM, Chan CL, Ode KL, Daley T, Stecenko AA, Moran A, Helmick MJ, Cray S, Alvarez JA, Stallings VA, Tuggle KL, Clancy JP, Eggerman TL, Engelhardt JF, Kelly A. Cystic Fibrosis-Related Diabetes Workshop: Research Priorities Spanning Disease Pathophysiology, Diagnosis, and Outcomes. Diabetes Care. 2023 06 01; 46(6):1112-1123.
    View in: PubMed
    Score: 0.005
  36. Kim YK, Walters JA, Moss ND, Wells KL, Sheridan R, Miranda JG, Benninger RKP, Pyle LL, O'Brien RM, Sussel L, Davidson HW. Zinc transporter 8 haploinsufficiency protects against beta cell dysfunction in type 1 diabetes by increasing mitochondrial respiration. Mol Metab. 2022 12; 66:101632.
    View in: PubMed
    Score: 0.005
  37. Sandoval DA, Alonso LC, Gannon M, Sander M, Sussel L, Reusch JEB. Career Advancement for Women in Diabetes-Related Research: Developing and Retaining Female Talent. Diabetes. 2021 08 01; 70(8):1634-1637.
    View in: PubMed
    Score: 0.004
  38. Sandoval DA, Alonso LC, Gannon M, Sander M, Sussel L, Reusch JEB. Career Advancement for Women in Diabetes-Related Research: Developing and Retaining Female Talent. Diabetes Care. 2021 08; 44(8):1744-1747.
    View in: PubMed
    Score: 0.004
  39. Kim YK, Sussel L, Davidson HW. Inherent Beta Cell Dysfunction Contributes to Autoimmune Susceptibility. Biomolecules. 2021 03 30; 11(4).
    View in: PubMed
    Score: 0.004
  40. Hudish LI, Bubak A, Triolo TM, Niemeyer CS, Lorberbaum DS, Sussel L, Nagel M, Taliaferro JM, Russ HA. Modeling Hypoxia-Induced Neuropathies Using a Fast and Scalable Human Motor Neuron Differentiation System. Stem Cell Reports. 2020 06 09; 14(6):1033-1043.
    View in: PubMed
    Score: 0.004
  41. Arnes L, Liu Z, Wang J, Maurer C, Sagalovskiy I, Sanchez-Martin M, Bommakanti N, Garofalo DC, Balderes DA, Sussel L, Olive KP, Rabadan R. Comprehensive characterisation of compartment-specific long non-coding RNAs associated with pancreatic ductal adenocarcinoma. Gut. 2019 03; 68(3):499-511.
    View in: PubMed
    Score: 0.003
  42. Ediger BN, Lim HW, Juliana C, Groff DN, Williams LT, Dominguez G, Liu JH, Taylor BL, Walp ER, Kameswaran V, Yang J, Liu C, Hunter CS, Kaestner KH, Naji A, Li C, Sander M, Stein R, Sussel L, Won KJ, May CL, Stoffers DA. LIM domain-binding 1 maintains the terminally differentiated state of pancreatic ß cells. J Clin Invest. 2017 01 03; 127(1):215-229.
    View in: PubMed
    Score: 0.003
  43. Halban PA, Polonsky KS, Bowden DW, Hawkins MA, Ling C, Mather KJ, Powers AC, Rhodes CJ, Sussel L, Weir GC. ß-cell failure in type 2 diabetes: postulated mechanisms and prospects for prevention and treatment. Diabetes Care. 2014 Jun; 37(6):1751-8.
    View in: PubMed
    Score: 0.003
  44. Halban PA, Polonsky KS, Bowden DW, Hawkins MA, Ling C, Mather KJ, Powers AC, Rhodes CJ, Sussel L, Weir GC. ß-cell failure in type 2 diabetes: postulated mechanisms and prospects for prevention and treatment. J Clin Endocrinol Metab. 2014 Jun; 99(6):1983-92.
    View in: PubMed
    Score: 0.003
  45. Nair KS, Abel ED, Adler SG, Dyck PJ, Gardner TW, Haskins KM, Hotamisligil G, Jensen MD, Krook A, Mandarino LJ, Mitchell BD, Pessin JE, Sowers JR, Sussel L, Wareham N, Vella A. Time to look back and to look forward. Diabetes. 2014 Apr; 63(4):1169-70.
    View in: PubMed
    Score: 0.003
  46. Lugani F, Arora R, Papeta N, Patel A, Zheng Z, Sterken R, Singer RA, Caridi G, Mendelsohn C, Sussel L, Papaioannou VE, Gharavi AG. A retrotransposon insertion in the 5' regulatory domain of Ptf1a results in ectopic gene expression and multiple congenital defects in Danforth's short tail mouse. PLoS Genet. 2013; 9(2):e1003206.
    View in: PubMed
    Score: 0.002
  47. Morán I, Akerman I, van de Bunt M, Xie R, Benazra M, Nammo T, Arnes L, Nakic N, García-Hurtado J, Rodríguez-Seguí S, Pasquali L, Sauty-Colace C, Beucher A, Scharfmann R, van Arensbergen J, Johnson PR, Berry A, Lee C, Harkins T, Gmyr V, Pattou F, Kerr-Conte J, Piemonti L, Berney T, Hanley N, Gloyn AL, Sussel L, Langman L, Brayman KL, Sander M, McCarthy MI, Ravassard P, Ferrer J. Human ß cell transcriptome analysis uncovers lncRNAs that are tissue-specific, dynamically regulated, and abnormally expressed in type 2 diabetes. Cell Metab. 2012 Oct 03; 16(4):435-48.
    View in: PubMed
    Score: 0.002
  48. Raum JC, Hunter CS, Artner I, Henderson E, Guo M, Elghazi L, Sosa-Pineda B, Ogihara T, Mirmira RG, Sussel L, Stein R. Islet beta-cell-specific MafA transcription requires the 5'-flanking conserved region 3 control domain. Mol Cell Biol. 2010 Sep; 30(17):4234-44.
    View in: PubMed
    Score: 0.002
  49. Jedlicka P, Sui X, Sussel L, Gutierrez-Hartmann A. Ets transcription factors control epithelial maturation and transit and crypt-villus morphogenesis in the mammalian intestine. Am J Pathol. 2009 Apr; 174(4):1280-90.
    View in: PubMed
    Score: 0.002
  50. Raum JC, Gerrish K, Artner I, Henderson E, Guo M, Sussel L, Schisler JC, Newgard CB, Stein R. FoxA2, Nkx2.2, and PDX-1 regulate islet beta-cell-specific mafA expression through conserved sequences located between base pairs -8118 and -7750 upstream from the transcription start site. Mol Cell Biol. 2006 Aug; 26(15):5735-43.
    View in: PubMed
    Score: 0.002
  51. Furuta H, Horikawa Y, Iwasaki N, Hara M, Sussel L, Le Beau MM, Davis EM, Ogata M, Iwamoto Y, German MS, Bell GI. Beta-cell transcription factors and diabetes: mutations in the coding region of the BETA2/NeuroD1 (NEUROD1) and Nkx2.2 (NKX2B) genes are not associated with maturity-onset diabetes of the young in Japanese. Diabetes. 1998 Aug; 47(8):1356-8.
    View in: PubMed
    Score: 0.001
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.

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