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Patrick J. Kearney

TitleAsst Professor Adjoint
InstitutionUniversity of Colorado Denver - Anschutz Medical Campus
DepartmentSOM-FM General Operations

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Zhuang Z, Togashi RK, Kearney P, Pass I, Swick SM, Zeng FY, Bobkov AA, Fujimoto LM, Dutta S, Zerva A, Raig ND, Saha D, Emami A, Schwalm MP, Moon BK, Howard ST, Knapp S, Hanke T, Chung TDY, Chen JK. Small-molecule modulators of HIPK4 activity and proteostasis. bioRxiv. 2026 May 14. PMID: 42182270.
      View in: PubMed
    2. Boyer NP, Sharma R, Wiesner T, Parperis C, Delamare A, Pelletier F, Jullien N, Bhatt AM, Parra-Rivas LA, Kearney PJ, Shavarebi F, Leterrier C, Roy S. Spectrin condensates provide a nidus for assembling the axonal membrane-associated periodic skeleton. iScience. 2026 Jan 16; 29(1):114454. PMID: 41536998.
      View in: PubMed
    3. Kearney PJ, Zhang Y, Liang M, Tan Y, Kahuno E, Conklin TL, Fagan RR, Pavchinskiy RG, Shaffer SA, Yue Z, Melikian HE. Silencing Parkinson's risk allele Rit2 sex-specifically compromises motor function and dopamine neuron viability. NPJ Parkinsons Dis. 2024 Feb 23; 10(1):41. PMID: 38395968.
      View in: PubMed
    4. Kearney PJ, Zhang Y, Tan Y, Kahuno E, Conklin TL, Fagan RR, Pavchinskiy RG, Shafer SA, Yue Z, Melikian HE. Rit2 silencing in dopamine neurons drives a Parkinsonian phenotype. bioRxiv. 2023 Nov 13. PMID: 37162843.
      View in: PubMed
    5. Cui T, Corrales-Guerrero S, Castro-Aceituno V, Nair S, Maneval DC, Monnig C, Kearney P, Ellis S, Raheja N, Raheja N, Williams TM. JNTX-101, a novel albumin-encapsulated gemcitabine prodrug, is efficacious and operates via caveolin-1-mediated endocytosis. Mol Ther Oncolytics. 2023 Sep 21; 30:181-192. PMID: 37674628.
      View in: PubMed
    6. Kearney PJ, Zhang Y, Tan Y, Kahuno E, Conklin TL, Fagan RR, Pavchinskiy RG, Shafer SA, Yue Z, Melikian HE. Rit2 silencing in dopamine neurons drives a progressive Parkinsonian phenotype. Res Sq. 2023 May 25. PMID: 37293098.
      View in: PubMed
    7. Kearney PJ, Bolden NC, Kahuno E, Conklin TL, Martin GE, Lubec G, Melikian HE. Presynaptic Gq-coupled receptors drive biphasic dopamine transporter trafficking that modulates dopamine clearance and motor function. J Biol Chem. 2023 02; 299(2):102900. PMID: 36640864.
      View in: PubMed
    8. Fagan RR, Kearney PJ, Luethi D, Bolden NC, Sitte HH, Emery P, Melikian HE. Dopaminergic Ric GTPase activity impacts amphetamine sensitivity and sleep quality in a dopamine transporter-dependent manner in Drosophila melanogaster. Mol Psychiatry. 2021 12; 26(12):7793-7802. PMID: 34471250.
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    9. Fagan RR, Kearney PJ, Melikian HE. In Situ Regulated Dopamine Transporter Trafficking: There's No Place Like Home. Neurochem Res. 2020 Jun; 45(6):1335-1343. PMID: 32146647.
      View in: PubMed
    10. Fagan RR, Kearney PJ, Sweeney CG, Luethi D, Schoot Uiterkamp FE, Schicker K, Alejandro BS, O'Connor LC, Sitte HH, Melikian HE. Dopamine transporter trafficking and Rit2 GTPase: Mechanism of action and in vivo impact. J Biol Chem. 2020 04 17; 295(16):5229-5244. PMID: 32132171.
      View in: PubMed
    11. Sweeney CG, Kearney PJ, Fagan RR, Smith LA, Bolden NC, Zhao-Shea R, Rivera IV, Kolpakova J, Xie J, Gao G, Tapper AR, Martin GE, Melikian HE. Conditional, inducible gene silencing in dopamine neurons reveals a sex-specific role for Rit2 GTPase in acute cocaine response and striatal function. Neuropsychopharmacology. 2020 01; 45(2):384-393. PMID: 31277075.
      View in: PubMed
    12. Macpherson LJ, Zaharieva EE, Kearney PJ, Alpert MH, Lin TY, Turan Z, Lee CH, Gallio M. Dynamic labelling of neural connections in multiple colours by trans-synaptic fluorescence complementation. Nat Commun. 2015 Dec 04; 6:10024. PMID: 26635273.
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    13. Frank DD, Jouandet GC, Kearney PJ, Macpherson LJ, Gallio M. Temperature representation in the Drosophila brain. Nature. 2015 Mar 19; 519(7543):358-61. PMID: 25739506.
      View in: PubMed
    14. Gabriel LR, Wu S, Kearney P, Bellvé KD, Standley C, Fogarty KE, Melikian HE. Dopamine transporter endocytic trafficking in striatal dopaminergic neurons: differential dependence on dynamin and the actin cytoskeleton. J Neurosci. 2013 Nov 06; 33(45):17836-46. PMID: 24198373.
      View in: PubMed
    15. Snyder QC, Kearney PJ. High +Gz induced acute inguinal herniation in an F-16 aircrew member: case report and review. Aviat Space Environ Med. 2002 Jan; 73(1):68-72. PMID: 11817622.
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    16. Kearney PJ, Li G. Geographic variations in crash risk of general aviation and air taxis. Aviat Space Environ Med. 2000 Jan; 71(1):19-21. PMID: 10632126.
      View in: PubMed
    17. Kearney PJ. Cases from the aerospace medicine residents' teaching file. Case #54. Fibrous dysplasia. Aviat Space Environ Med. 1993 Oct; 64(10):955-6. PMID: 8240203.
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