 Jonathan Irish
| Title | Professor |
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| Institution | University of Colorado Denver - Anschutz Medical Campus |
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| Department | SOM-PEDS |
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ORCID
.gif) | 0000-0001-9428-8866  |
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 Biography | Stanford University, Palo Alto, CA | PhD | 04/2004 | Cancer Biology | | University of Michigan, Ann Arbor, MI | BS, Chem. | 05/1998 | Chemistry | | University of Michigan, Ann Arbor, MI | BS | 05/1998 | Biology, Honors | | University of Michigan, Ann Arbor, MI | BS | 05/1998 | Biochemistry |
Overview The Irish lab studies how signaling governs cell identity in healthy human tissue and in diseases, including brain tumors, blood cancers, and immune disorders. Dr. Irish is an expert in the identification and functional characterization of human cells. Research in the Irish lab emphasizes integrated creation and use of bench and computational techniques. The Irish lab leads the CytoLab data science team at CU Anschutz and is based in Pediatrics-Neurology. Dr. Irish previously trained at Stanford for PhD and postdoc (2004-2011) and directed a research group and shared resource at Vanderbilt University (2012-2024).
Irish Lab Website:
https://www.irishlab.org/
Jonathan Irish on Google Scholar:
https://scholar.google.com/citations?user=-IJndUMAAAAJ
Bibliographic
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Sawka AM, Ghai S, Rotstein L, Irish JC, Pasternak JD, Monteiro E, Chung J, Su J, Xu W, Esemezie AO, Jones JM, Gafni A, Baxter NN, Goldstein DP. Long-Term Durability of Active Surveillance of Small, Low-Risk Papillary Thyroid Cancer. JAMA Surg. 2025 Oct 01; 160(10):1117-1124. PMID: 40833769.
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Gau M, Su J, Huang SH, Alfaraj FA, Olson R, Marta GN, Kowalski LP, Kohler HF, de Matos LL, Moraes FY, Xu W, Sanz-Garcia E, Hahn E, Kim JJ, McPartlin A, O'Sullivan B, Tsai CJ, Waldron J, Prisman E, Irish JC, Yao CMKL, de Almeida JR, Goldstein DP, Hope A, Hosni A. Nomogram for Risk-Adaptive Estimation of the Locoregional Control Benefit Following Postoperative Radiation Therapy for Pathologic N0 Oral Cavity Cancer: A Retrospective Analysis. Int J Radiat Oncol Biol Phys. 2025 Sep 17. PMID: 40972905.
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Moore C, Petrovic B, Bender JL, Thompson C, McLeod SL, Savage D, Borgundvaag B, Ovens H, Irish J, Eskander A, Cheskes S, Krzyzanowska M, de Wit K, Mohindra R, Thiruganasambandamoorthy V, Grewal K. Emergency physicians' experiences managing patients with a suspected cancer diagnosis in Ontario, Canada: a qualitative study. BMJ Open. 2025 Sep 08; 15(9):e096506. PMID: 40921644.
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Thirman HL, Grider-Hayes MJ, Geben LC, Ihrie RA, Brown LE, Porco JA, Irish JM. Connecting chemical structure to single cell signaling profiles. Commun Biol. 2025 Jul 31; 8(1):1137. PMID: 40745386.
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Valic MS, Fisher CJ, Zheng M, Gregor AM, Jiang W, Chan C, Chan HHL, El-Sayes A, Zhang CJ, Ye T, Halim M, Schimmer P, Li C, Bernards N, Chu ACK, Cai Z, Chen J, Irish JC, Yasufuku K, Weersink R, Reilly RM, Wilson BC, Zheng G. Radiopharmaceutical kit to prepare Copper-64 labelled porphyrin-lipid nanoparticles for radiotracer imaging studies in cancer patients. Eur J Nucl Med Mol Imaging. 2025 Jul 17. PMID: 40676182.
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Levy BB, Goodman J, Gomes A, Martino R, Noel CW, Kamalraj P, Wright FC, Irish JC, Conn LG, Eskander A. Challenges and Opportunities for Speech-Language Pathology Services in Comprehensive Head and Neck Cancer Care: Insights From a Mixed Methods Study. Head Neck. 2025 Nov; 47(11):3131-3140. PMID: 40611542.
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Grewal K, Calzavara A, McLeod SL, Eskander A, Savage DW, Thompson C, Borgundvaag B, Ovens H, Cheskes S, de Wit K, Irish JC, Krzyzanowska MK, Walsh R, Thiruganasambandamoorthy V, Sutradhar R. Emergency Department Use Prior to Cancer Diagnosis and Mortality. JAMA Netw Open. 2025 07 01; 8(7):e2522585. PMID: 40694345.
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Seyedi P, Aleman D, Baxter NN, Bell CM, Bodur M, Calzavara A, Campbell R, Carter M, de Jager P, Emerson SD, Irish J, Martin D, Lee S, Persitz J, Saxe-Braithwaite M, Takata J, Varkul O, Yang S, Zanchetta C, Urbach DR. Effect of single-entry referral models and team-based care on wait times for hip and knee joint replacement in Ontario: a simulation study. CMAJ. 2025 05 19; 197(19):E524-E531. PMID: 40393716.
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Valic MS, Zheng M, Husby T, Guidolin K, Sahovaler A, Tzelnick S, Jiang W, Halim M, Schimmer P, El-Sayes A, Zhang CJ, Ye T, Kosik I, Townson JL, Ng KK, Ding L, Chen J, Irish JC, Weersink R, Wilson BC, Zheng G. Cutaneous photosensitivity of phototheranostic porphyrin-lipid nanoparticles. Photochem Photobiol. 2025 Apr 07. PMID: 40191965.
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Seyedi P, Aleman D, Baxter N, Bell C, Bodur M, Calzavara A, Campbell R, Carter M, de Jager P, Emerson S, Gagliardi A, Irish J, Martin D, Lee S, Saxe-Braithwaite M, Takata J, Yang S, Zanchetta C, Urbach D. Referral patterns for common surgical procedures in Ontario: a cross-sectional population-level study. Can J Surg. 2024 Nov-Dec; 67(6):E397-E405. PMID: 39672555.
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Ferrari M, Gaudioso P, Taboni S, Contro G, Roccuzzo G, Costantino P, Daly MJ, Chan HHL, Fieux M, Ruaro A, Maroldi R, Signoroni A, Deganello A, Irish JC, Carsuzaa F, Nicolai P. Intraoperative surgical navigation improves margin status in advanced malignancies of the anterior craniofacial area: A prospective observational study with systematic review of the literature and meta-analysis. Eur J Surg Oncol. 2025 Feb; 51(2):109514. PMID: 39662109.
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Kim HAJ, De Biasio MJ, Forte V, Gilbert RW, Irish JC, Goldstein DP, de Almeida JR, Hanasono MM, Yu P, Chepeha DB, Looi T, Yao CMKL. Optimizing Osteotomy Geometries in Posterolateral Mandibulectomies. JAMA Otolaryngol Head Neck Surg. 2024 Dec 01; 150(12):1113-1120. PMID: 39480439.
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Grewal K, Calzavara A, McLeod SL, Eskander A, Savage DW, Thompson C, Borgundvaag B, Ovens H, Cheskes S, de Wit K, Irish J, Krzyzanowska MK, Walsh R, Mohindra R, Thiruganasambandamoorthy V, Sutradhar R. Emergency department use before cancer diagnosis in Ontario, Canada: a population-based study. CMAJ. 2024 11 03; 196(37):E1252-E1261. PMID: 39496352.
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Rooney CM, Huang SH, Su J, Bratman S, Cho J, de Almeida J, Glogauer M, Goldstein D, Hahn E, Hosni A, Hope A, Irish J, Kim J, O'Sullivan B, Ringash J, Spreafico A, Tsai J, Waldron J, Yao C, Watson E, McPartlin A. Impact of Postoperative Neck Radiotherapy Volumes on Long-Term Unstimulated Saliva Flow Following Primary Surgery and Ipsilateral Neck Dissection for Oral Cavity Squamous Cell Carcinoma. Head Neck. 2025 Mar; 47(3):847-855. PMID: 39474724.
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Wihlidal J, Esemezie AO, Huang SH, Watson E, Gilbert RW, Waldron J, Gullane PJ, Hope A, Irish JC, O'Sullivan B, Chepeha DB, Kim JJH, Brown D, Cho BCJ, Witterick IJ, Monteiro E, Davies JC, Ringash J, Goldstein DP, Bratman S, Bayley A, de Almeida JR, Chan TCY, Hosni A, Yao CMKL. Impact of Surgeon-Radiation Oncology Dyads in Oral Cavity Cancer Outcomes. Ann Surg Oncol. 2025 Feb; 32(2):1270-1279. PMID: 39467971.
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Crosina J, Wright F, Irish J, Rashid M, Martin T, Hirpara DH, Hunter A, Sundaresan S. Long-Term Impact of Regionalization of Thoracic Oncology Surgery. Ann Thorac Surg. 2025 Feb; 119(2):460-469. PMID: 39442904.
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Grewal K, Thompson C, Ovens H, Sutradhar R, Savage DW, Borgundvaag B, Cheskes S, de Wit K, Eskander A, Irish J, Bender JL, Krzyzanowska M, Mohindra R, Thiruganasambandamoorthy V, McLeod SL. Pathways to cancer care after a suspected cancer diagnosis in the emergency department: a survey of emergency physicians across Ontario. CJEM. 2024 12; 26(12):865-874. PMID: 39373854.
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Ruaro A, Taboni S, Chan HHL, Mondello T, Lindsay P, Komal T, Alessandrini L, Sbaraglia M, Bellan E, Maroldi R, Townson J, Daly MJ, Re F, Pasini C, Krengli M, Sartore L, Russo D, Nicolai P, Ferrari M, Gilbert RW, Irish JC. Development of a Preclinical Double Model of Mandibular Irradiated Bone and Osteoradionecrosis in New Zealand Rabbits. Head Neck. 2025 Feb; 47(2):625-634. PMID: 39363401.
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Syrimi E, Khan N, Murray P, Willcox C, Haigh T, Willcox B, Masand N, Bowen C, Dimakou DB, Zuo J, Barone SM, Irish JM, Kearns P, Taylor GS. Defects in NK cell immunity of pediatric cancer patients revealed by deep immune profiling. iScience. 2024 Sep 20; 27(9):110837. PMID: 39310750.
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Campbell RJ, El-Defrawy SR, Bell CM, Urbach DR, Paterson JM, Stukel TA, Gill SS, Irish J, Baxter NN, Wilton AS, Gomez D. Public funding for private for-profit centres and access to cataract surgery by patient socioeconomic status: an Ontario population-based study. CMAJ. 2024 08 25; 196(28):E965-E972. PMID: 39187289.
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de Jager P, Aleman D, Baxter N, Bell C, Bodur M, Calzavara A, Campbell R, Carter M, Emerson S, Gagliardi A, Irish J, Martin D, Lee S, SaxeBraithwaite M, Seyedi P, Takata J, Yang S, Zanchetta C, Urbach DR. Surgeon- and hospital-level variation in wait times for scheduled non-urgent surgery in Ontario, Canada: A cross-sectional population-based study. PLoS One. 2024; 19(8):e0307845. PMID: 39116181.
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Sankar A, Stukel TA, Baxter NN, Wijeysundera DN, Hwang SW, Wilton AS, Chan TCY, Sarhangian V, Simpson AN, de Mestral C, Pincus D, Campbell RJ, Urbach DR, Irish J, Gomez D. Disparities in surgery rates during the COVID-19 pandemic: retrospective study. BJS Open. 2024 Jul 02; 8(4). PMID: 39186678.
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Voss K, Bartkowiak T, Sewell AE, Chi C, Landis MD, Schaefer S, Pua HH, Connelly JA, Irish JM, Rathmell JC, Kaviany S. Peripheral T Cell Development and Immunophenotyping of Twins with Heterozygous FOXN1 Mutations. Immunohorizons. 2024 07 01; 8(7):492-499. PMID: 39008056.
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Lazar NH, Celik S, Chen L, Fay MM, Irish JC, Jensen J, Tillinghast CA, Urbanik J, Bone WP, Gibson CC, Haque IS. High-resolution genome-wide mapping of chromosome-arm-scale truncations induced by CRISPR-Cas9 editing. Nat Genet. 2024 Jul; 56(7):1482-1493. PMID: 38811841.
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Tentori CA, Zhao LP, Tinterri B, Strange KE, Zoldan K, Dimopoulos K, Feng X, Riva E, Lim B, Simoni Y, Murthy V, Hayes MJ, Poloni A, Padron E, Cardoso BA, Cross M, Winter S, Santaolalla A, Patel BA, Groarke EM, Wiseman DH, Jones K, Jamieson L, Manogaran C, Daver N, Gallur L, Ingram W, Ferrell PB, Sockel K, Dulphy N, Chapuis N, Kubasch AS, Olsnes AM, Kulasekararaj A, De Lavellade H, Kern W, Van Hemelrijck M, Bonnet D, Westers TM, Freeman S, Oelschlaegel U, Valcarcel D, Raddi MG, Grønbæk K, Fontenay M, Loghavi S, Santini V, Almeida AM, Irish JM, Sallman DA, Young NS, van de Loosdrecht AA, Adès L, Della Porta MG, Cargo C, Platzbecker U, Kordasti S. Immune-monitoring of myelodysplastic neoplasms: Recommendations from the i4MDS consortium. Hemasphere. 2024 May; 8(5):e64. PMID: 38756352.
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Chan HHL, Nayak P, Alshaygy I, Gundle KR, Tsoi K, Daly MJ, Irish JC, Ferguson PC, Wunder JS. Does Freehand, Patient-specific Instrumentation or Surgical Navigation Perform Better for Allograft Reconstruction After Tumor Resection? A Preclinical Synthetic Bone Study. Clin Orthop Relat Res. 2024 Oct 01; 482(10):1896-1908. PMID: 38813958.
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Cross CE, Mayeda C, Medina S, Hayes MJ, Kaviany S, Connelly JA, Rathmell JC, Weaver KD, Thompson RC, Chambless LB, Ihrie RA, Irish JM. Velociraptor: Cross-Platform Quantitative Search Using Hallmark Cell Features. bioRxiv. 2024 May 04. PMID: 38746337.
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Thirman HL, Hayes MJ, Brown LE, Porco JA, Irish JM. Single Cell Profiling Distinguishes Leukemia-Selective Chemotypes. bioRxiv. 2024 May 03. PMID: 38826485.
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Eu D, Daly MJ, Taboni S, Sahovaler A, Gilbank AN, Irish JC. Evaluation of a 3D Printed Silicone Oral Cavity Cancer Model for Surgical Simulations. J Pers Med. 2024 Apr 25; 14(5). PMID: 38793031.
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Gete M, Huang SH, Ringash J, Irish J, Su J, Ballal Y, Waldron JN, Witterick I, de Almeida J, Hosni A, Hope AJ, Monteiro E, Cho J, O'Sullivan B, Kim J, Bratman S, Goldstein DP, McPartlin A, Tsai J, Tong L, Xu W, Hahn E. Causes and impact of delays during the COVID-19 pandemic on head and neck cancer diagnosis. Head Neck. 2024 09; 46(9):2197-2205. PMID: 38665037.
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Namavarian A, Gabinet-Equihua A, Deng Y, Khalid S, Ziai H, Deutsch K, Huang J, Gilbert RW, Goldstein DP, Yao CMKL, Irish JC, Enepekides DJ, Higgins KM, Rudzicz F, Eskander A, Xu W, de Almeida JR. Length of Stay Prediction Models for Oral Cancer Surgery: Machine Learning, Statistical and ACS-NSQIP. Laryngoscope. 2024 Aug; 134(8):3664-3672. PMID: 38651539.
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Sawka AM, Ghai S, Rotstein L, Irish JC, Pasternak JD, Monteiro E, Chung J, Zahedi A, Su J, Xu W, Jones JM, Gafni A, Baxter NN, Goldstein DP. Decision Regret Following the Choice of Surgery or Active Surveillance for Small, Low-Risk Papillary Thyroid Cancer: A Prospective Cohort Study. Thyroid. 2024 05; 34(5):626-634. PMID: 38481111.
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von Lersner AK, Fernandes F, Ozawa PMM, Jackson M, Masureel M, Ho H, Lima SM, Vagner T, Sung BH, Wehbe M, Franze K, Pua H, Wilson JT, Irish JM, Weaver AM, Di Vizio D, Zijlstra A. Multiparametric Single-Vesicle Flow Cytometry Resolves Extracellular Vesicle Heterogeneity and Reveals Selective Regulation of Biogenesis and Cargo Distribution. ACS Nano. 2024 04 16; 18(15):10464-10484. PMID: 38578701.
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Chepeha DB, Barbon CEA, Esemezie AO, Al Mardini M, Philteos J, Spector ME, Bressmann T, Martino R, Bratman SV, Cho JBC, Hope AJ, Hosni AA, Kim JJH, Ringash JG, Waldron JN, Brown DH, de Almeida JR, Gilbert RW, Goldstein DP, Gullane PJ, Irish JC, Monteiro EA, Yao CMKL. Telemedicine-enabled biofeedback electropalatography rehabilitation (TEBER): A pilot study for patients treated with surgery for oral cavity carcinoma. Head Neck. 2024 07; 46(7):1737-1751. PMID: 38561946.
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Medina S, Brockman AA, Cross CE, Hayes MJ, Mobley BC, Mistry AM, Chotai S, Weaver KD, Thompson RC, Chambless LB, Ihrie RA, Irish JM. IL-8 Instructs Macrophage Identity in Lateral Ventricle Contacting Glioblastoma. bioRxiv. 2024 Mar 30. PMID: 38585888.
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Sahovaler A, Valic MS, Townson JL, Chan HHL, Zheng M, Tzelnick S, Mondello T, Pener-Tessler A, Eu D, El-Sayes A, Ding L, Chen J, Douglas CM, Weersink R, Muhanna N, Zheng G, Irish JC. Nanoparticle-mediated Photodynamic Therapy as a Method to Ablate Oral Cavity Squamous Cell Carcinoma in Preclinical Models. Cancer Res Commun. 2024 03 15; 4(3):796-810. PMID: 38421899.
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Levy BB, Goodman J, Watson E, Gilbert M, Blanas N, Noel CW, Kamalraj P, Wright FC, Irish JC, Conn LG, Eskander A. A scoping assessment of dental services at designated head and neck cancer centres in Ontario, Canada. BMC Oral Health. 2024 Feb 13; 24(1):232. PMID: 38350886.
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de Jager P, Aleman D, Baxter N, Bell C, Bodur M, Calzavara A, Campbell R, Carter M, Emerson S, Gagliardi A, Irish J, Martin D, Lee S, Saxe-Braithwaite M, Seyedi P, Takata J, Yang S, Zanchetta C, Urbach D. Social determinants of access to timely elective surgery in Ontario, Canada: a cross-sectional population level study. CMAJ Open. 2023 Nov-Dec; 11(6):E1164-E1180. PMID: 38114259.
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Brière R, Émond M, Benhamed A, Blanchard PG, Drolet S, Habashi R, Golbon B, Shellenberger J, Pasternak J, Merchant S, Shellenberger J, La J, Sawhney M, Brogly S, Cadili L, Horkoff M, Ainslie S, Demetrick J, Chai B, Wiseman K, Hwang H, Alhumoud Z, Salem A, Lau R, Aw K, Nessim C, Gawad N, Alibhai K, Towaij C, Doan D, Raîche I, Valji R, Turner S, Balmes PN, Hwang H, Hameed SM, Tan JGK, Wijesuriya R, Tan JGK, Hew NLC, Wijesuriya R, Lund M, Hawel J, Gregor J, Leslie K, Lenet T, McIsaac D, Hallet J, Jerath A, Lalu M, Nicholls S, Presseau J, Tinmouth A, Verret M, Wherrett C, Fergusson D, Martel G, Sharma S, McKechnie T, Talwar G, Patel J, Heimann L, Doumouras A, Hong D, Eskicioglu C, Wang C, Guo M, Huang L, Sun S, Davis N, Wang J, Skulsky S, Sikora L, Raîche I, Son HJ, Gee D, Gomez D, Jung J, Selvam R, Seguin N, Zhang L, Lacaille-Ranger A, Sikora L, McIsaac D, Moloo H, Follett A, Organ M, Pace D, Balvardi S, Kaneva P, Semsar-Kazerooni K, Mueller C, Vassiliou M, Al Mahroos M, Fiore JF, Schwartzman K, Feldman L, Guo M, Karimuddin A, Liu GP, Crump T, Sutherland J, Hickey K, Bonisteel EM, Umali J, Dogar I, Warden G, Boone D, Mathieson A, Hogan M, Pace D, Seguin N, Moloo H, Li Y, Best G, Leong R, Wiseman S, Alaoui AA, Hajjar R, Wassef E, Metellus DS, Dagbert F, Loungnarath R, Ratelle R, Schwenter F, Debroux É, Wassef R, Gagnon-Konamna M, Pomp A, Richard CS, Sebajang H, Alaoui AA, Hajjar R, Dagbert F, Loungnarath R, Sebajang H, Ratelle R, Schwenter F, Debroux É, Wassef R, Gagnon-Konamna M, Pomp A, Santos MM, Richard CS, Shi G, Leung R, Lim C, Knowles S, Parmar S, Wang C, Debru E, Mohamed F, Anakin M, Lee Y, Samarasinghe Y, Khamar J, Petrisor B, McKechnie T, Eskicioglu C, Yang I, Mughal HN, Bhugio M, Gok MA, Khan UA, Fernandes AR, Spence R, Porter G, Hoogerboord CM, Neumann K, Pillar M, Guo M, Manhas N, Melck A, Kazi T, McKechnie T, Jessani G, Heimann L, Lee Y, Hong D, Eskicioglu C, McKechnie T, Tessier L, Archer V, Park L, Cohen D, Parpia S, Bhandari M, Dionne J, Eskicioglu C, Bolin S, Afford R, Armstrong M, Karimuddin A, Leung R, Shi G, Lim C, Grant A, Van Koughnett JA, Knowles S, Clement E, Lange C, Roshan A, Karimuddin A, Scott T, Nadeau K, Macmillan J, Wilson J, Deschenes M, Nurullah A, Cahill C, Chen VH, Patterson KM, Wiseman SM, Wen B, Bhudial J, Barton A, Lie J, Park CM, Yang L, Gouskova N, Kim DH, Afford R, Bolin S, Morris-Janzen D, McLellan A, Karimuddin A, Archer V, Cloutier Z, Berg A, McKechnie T, Wiercioch W, Eskicioglu C, Labonté J, Bisson P, Bégin A, Cheng-Oviedo SG, Collin Y, Fernandes AR, Hossain I, Ellsmere J, El-Kefraoui C, Do U, Miller A, Kouyoumdjian A, Cui D, Khorasani E, Landry T, Amar-Zifkin A, Lee L, Feldman L, Fiore J, Au TM, Oppenheimer M, Logsetty S, AlShammari R, AlAbri M, Karimuddin A, Brown C, Raval MJ, Phang PT, Bird S, Baig Z, Abu-Omar N, Gill D, Suresh S, Ginther N, Karpinski M, Ghuman A, Malik PRA, Alibhai K, Zabolotniuk T, Raîche I, Gawad N, Mashal S, Boulanger N, Watt L, Razek T, Fata P, Grushka J, Wong EG, Hossain I, Landry M, Mackey S, Fairbridge N, Greene A, Borgoankar M, Kim C, DeCarvalho D, Pace D, Wigen R, Walser E, Davidson J, Dorward M, Muszynski L, Dann C, Seemann N, Lam J, Harding K, Lowik AJ, Guinard C, Wiseman S, Ma O, Mocanu V, Lin A, Karmali S, Bigam D, Harding K, Greaves G, Parker B, Nguyen V, Ahmed A, Yee B, Perren J, Norman M, Grey M, Perini R, Jowhari F, Bak A, Drung J, Allen L, Wiseman D, Moffat B, Lee JKH, McGuire C, Raîche I, Tudorache M, Gawad N, Park LJ, Borges FK, Nenshi R, Jacka M, Heels-Ansdell D, Simunovic M, Bogach J, Serrano PE, Thabane L, Devereaux PJ, Farooq S, Lester E, Kung J, Bradley N, Best G, Ahn S, Zhang L, Prince N, Cheng-Boivin O, Seguin N, Wang H, Quartermain L, Tan S, Shamess J, Simard M, Vigil H, Raîche I, Hanna M, Moloo H, Azam R, Ko G, Zhu M, Raveendran Y, Lam C, Tang J, Bajwa A, Englesakis M, Reel E, Cleland J, Snell L, Lorello G, Cil T, Ahn HS, Dube C, McIsaac D, Smith D, Leclerc A, Shamess J, Rostom A, Calo N, Thavorn K, Moloo H, Laplante S, Liu L, et al. 2023 Canadian Surgery Forum: Sept. 20-23, 2023. Can J Surg. 2023 Nov-Dec; 66(6 Suppl 1):S54-S136. PMID: 38173057.
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Id Said B, Alfaraj FA, Marta GN, Kowalski LP, Kohler HF, Huang SH, Su J, Xu W, Eng L, de Moraes FY, Hahn E, Kim JJ, O'Sullivan B, Ringash J, Waldron J, Matos LL, Prisman E, Irish JC, Yao CMKL, de Almeida JR, Goldstein DP, Hope A, Hosni A. Individualized risk assessment of distant metastases in oral cavity carcinoma: a validated predictive-score model. J Natl Cancer Inst. 2023 12 06; 115(12):1555-1562. PMID: 37498564.
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Bewersdorf JP, Shallis RM, Sharon E, Park S, Ramaswamy R, Roe CE, Irish JM, Caldwell A, Wei W, Yacoub A, Madanat YF, Zeidner JF, Altman JK, Odenike O, Yerrabothala S, Kovacsovics T, Podoltsev NA, Halene S, Little RF, Piekarz R, Gore SD, Kim TK, Zeidan AM. A multicenter phase Ib trial of the histone deacetylase inhibitor entinostat in combination with pembrolizumab in patients with myelodysplastic syndromes/neoplasms or acute myeloid leukemia refractory to hypomethylating agents. Ann Hematol. 2024 Jan; 103(1):105-116. PMID: 38036712.
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Norlander AE, Abney M, Cephus JY, Roe CE, Irish JM, Shelburne NJ, Newcomb DC, Hemnes AR, Peebles RS. Reply to Yasuma et al. Am J Respir Crit Care Med. 2023 12 01; 208(11):1249-1250. PMID: 37774400.
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Chen T, Chan HHL, de Almeida J, Goldstein DP, Gilbert RW, Yao CMKL, Irish JC, Davies JC. A 3D Analysis of Plating Strategies in Mandibular Reconstruction: A Randomized Control Pilot Study. Laryngoscope. 2024 May; 134(5):2182-2186. PMID: 37962081.
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Stephenson R, Sarhangian V, Park J, Sankar A, Baxter NN, Stukel TA, Simpson AN, Wijeysundera DN, Wilton AS, de Mestral C, Hwang SW, Pincus D, Campbell RJ, Urbach DR, Irish J, Gomez D, Chan TCY. Evolution of the surgical procedure gap during and after the COVID-19 pandemic in Ontario, Canada: cross-sectional and modelling study. Br J Surg. 2023 11 09; 110(12):1887-1889. PMID: 37724806.
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Saadat LV, Schofield E, Bai X, Curry M, Saskin R, Lipitz-Snyderman A, Soares KC, Kingham TP, Jarnagin WR, D'Angelica MI, Wright FC, Irish JC, Coburn NG, Wei AC. Treatment Patterns and Outcomes in Pancreatic Cancer: A Comparative Analysis of Ontario and the USA. Ann Surg Oncol. 2024 Jan; 31(1):58-65. PMID: 37833463.
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Hirpara DH, Irish J, Rashid M, Martin T, Zhu A, Hunter A, Jayaraman S, Wei AC, Coburn NG, Wright FC. Defining Standards for Hepatopancreatobiliary Cancer Surgery in Ontario, Canada: A Population-Based Cohort Study of Clinical Outcomes. J Am Coll Surg. 2024 Feb 01; 238(2):157-165. PMID: 37796140.
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Norlander AE, Abney M, Cephus JY, Roe CE, Irish JM, Shelburne NJ, Newcomb DC, Hemnes AR, Peebles RS. Prostaglandin I2 Therapy Promotes Regulatory T Cell Generation in Patients with Pulmonary Arterial Hypertension. Am J Respir Crit Care Med. 2023 09 15; 208(6):737-739. PMID: 37413696.
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Sawka AM, Ghai S, Rotstein L, Irish JC, Pasternak JD, Gullane PJ, Monteiro E, Zahedi A, Gooden E, Eskander A, Chung J, Devon K, Su J, Xu W, Jones JM, Gafni A, Baxter NN, Goldstein DP. Gender Differences in Fears Related to Low-Risk Papillary Thyroid Cancer and Its Treatment. JAMA Otolaryngol Head Neck Surg. 2023 09 01; 149(9):803-810. PMID: 37410454.
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Senosain MF, Zou Y, Patel K, Zhao S, Coullomb A, Rowe DJ, Lehman JM, Irish JM, Maldonado F, Kammer MN, Pancaldi V, Lopez CF. Integrated Multi-omics Analysis of Early Lung Adenocarcinoma Links Tumor Biological Features with Predicted Indolence or Aggressiveness. Cancer Res Commun. 2023 07; 3(7):1350-1365. PMID: 37501683.
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Jablonska PA, Parent A, La Macchia N, Chan HHL, Filleti M, Ramotar M, Cho YB, Braganza M, Badzynski A, Laperriere N, Conrad T, Tsang DS, Shultz D, Santiago A, Irish JC, Millar BA, Tadic T, Berlin A. A total inverse planning paradigm: Prospective clinical trial evaluating the performance of a novel MR-based 3D-printed head immobilization device. Clin Transl Radiat Oncol. 2023 Sep; 42:100663. PMID: 37587925.
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Tzelnick S, Soroka HP, Tasnim N, Gilbert RW, Irish JC, Goldstein DP, Brown D, Gullane P, Chepeha DB, Yao CMKL, Sahovaler A, Witterick IJ, Monteiro E, Davies J, Huang SH, O'Sullivan B, Hahn E, Hosni A, Razak AA, Gupta AA, de Almeida JR. The impact of surgical resection margins on outcomes for adults with head and neck osteosarcomas: A Canadian sarcoma research and Clinical Collaboration (CanSaRCC) study. Oral Oncol. 2023 10; 145:106495. PMID: 37478572.
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Bartkowiak T, Lima SM, Hayes MJ, Mistry AM, Brockman AA, Sinnaeve J, Leelatian N, Roe CE, Mobley BC, Chotai S, Weaver KD, Thompson RC, Chambless LB, Ihrie RA, Irish JM. An immunosuppressed microenvironment distinguishes lateral ventricle-contacting glioblastomas. JCI Insight. 2023 06 22; 8(12). PMID: 37192001.
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Chepeha DB, Esemezie AO, Philteos J, Brown DH, de Almeida JR, Gilbert RW, Goldstein DP, Gullane PJ, Irish JC, Yao CM, Barbon CEA. Glossectomy for the treatment of oral cavity carcinoma: Quantitative, functional and patient-reported quality of life outcomes differ by four glossectomy defects. Oral Oncol. 2023 07; 142:106431. PMID: 37263070.
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Fu R, Sutradhar R, Li Q, Hanna TP, Chan KKW, Irish JC, Coburn N, Hallet J, Dare A, Singh S, Parmar A, Earle CC, Lapointe-Shaw L, Krzyzanowska MK, Finelli A, Louie AV, Look Hong NJ, Witterick IJ, Mahar A, Urbach DR, McIsaac DI, Enepekides D, Eskander A. Association between the COVID-19 pandemic and first cancer treatment modality: a population-based cohort study. CMAJ Open. 2023 May-Jun; 11(3):E426-E433. PMID: 37160325.
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Lui JT, Dahm V, Chen JM, Lin VY, Irish JC, Le TN, Chan HHL. Using augmented reality to guide bone conduction device implantation. Sci Rep. 2023 05 03; 13(1):7182. PMID: 37137995.
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Tzelnick S, Rampinelli V, Sahovaler A, Franz L, Chan HHL, Daly MJ, Irish JC. Skull-Base Surgery-A Narrative Review on Current Approaches and Future Developments in Surgical Navigation. J Clin Med. 2023 Apr 04; 12(7). PMID: 37048788.
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Fu R, Sutradhar R, Li Q, Kamalraj P, Dare A, Hanna TP, Chan KKW, Irish JC, Coburn N, Hallet J, Singh S, Parmar A, Earle CC, Lapointe-Shaw L, Krzyzanowska MK, Louie AV, Mahar A, Urbach DR, McIsaac DI, Enepekides D, Gomez D, Look Hong NJ, Tinmouth J, Eskander A. Early survival for patients newly diagnosed with cancer during COVID-19 in Ontario, Canada: A population-based cohort study. Cancer Med. 2023 05; 12(10):11849-11859. PMID: 36999960.
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Wright FC, Milkovich J, Hunter A, Darling G, Irish J. Refining the thoracic surgical oncology regionalization standards for esophageal surgery in Ontario, Canada: Moving from good to better. J Thorac Cardiovasc Surg. 2023 12; 166(6):1502-1509. PMID: 37005118.
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Geben LC, Brockman AA, Chalkley MBL, Sweet SR, Gallagher JE, Scheuing AL, Simerly RB, Ess KC, Irish JM, Ihrie RA. Dephosphorylation of 4EBP1/2 Induces Prenatal Neural Stem Cell Quiescence. bioRxiv. 2023 Feb 15. PMID: 36824760.
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Brockman AA, Khurana R, Bartkowiak T, Thomas PL, Sivagnanam S, Betts CB, Coussens LM, Lovly CM, Irish JM, Ihrie RA. Alignment, segmentation and neighborhood analysis in cyclic immunohistochemistry data using CASSATT. Cytometry B Clin Cytom. 2023 09; 104(5):344-355. PMID: 36748312.
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Noel CW, Sutradhar R, Chan WC, Fu R, Philteos J, Forner D, Irish JC, Vigod S, Isenberg-Grzeda E, Coburn NG, Hallet J, Eskander A. Gaps in Depression Symptom Management for Patients With Head and Neck Cancer. Laryngoscope. 2023 10; 133(10):2638-2646. PMID: 36748910.
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Ballal Y, Gete M, Su J, O'Sullivan B, Waldron JN, Irish J, Ringash J, Kim J, Bratman S, Cho J, Hope AJ, Hosni A, de Almeida J, Goldstein DP, Witterick I, Monteiro E, Tong L, Xu W, Hui Huang S, Hahn E. The collateral impact of the COVID-19 pandemic on HPV-positive oropharyngeal cancer diagnosis. Oral Oncol. 2023 03; 138:106332. PMID: 36780824.
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Alexander MR, Dale BL, Smart CD, Elijovich F, Wogsland CE, Lima SM, Irish JM, Madhur MS. Immune Profiling Reveals Decreases in Circulating Regulatory and Exhausted T Cells in Human Hypertension. JACC Basic Transl Sci. 2023 Mar; 8(3):319-336. PMID: 37034287.
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Fu R, Sutradhar R, Li Q, Hanna TP, Chan KKW, Irish JC, Coburn N, Hallet J, Dare A, Singh S, Parmar A, Earle CC, Lapointe-Shaw L, Krzyzanowska MK, Finelli A, Louie AV, Hong NJL, Witterick IJ, Mahar A, Urbach DR, McIsaac DI, Enepekides D, Tinmouth J, Eskander A. Timeliness and Modality of Treatment for New Cancer Diagnoses During the COVID-19 Pandemic in Canada. JAMA Netw Open. 2023 01 03; 6(1):e2250394. PMID: 36626169.
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Noel CW, Hueniken K, Forner D, Liu G, Eng L, Hosni A, Hahn E, Irish JC, Gilbert R, Yao CMKL, Monteiro E, O'Sullivan B, Waldron J, Huang SH, Goldstein DP, de Almeida JR. Association of Household Income at Diagnosis With Financial Toxicity, Health Utility, and Survival in Patients With Head and Neck Cancer. JAMA Otolaryngol Head Neck Surg. 2023 01 01; 149(1):63-70. PMID: 36416855.
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Gomez D, de Mestral C, Stukel TA, Irish J, Simpson AN, Wilton AS, Rotstein OD, Campbell RJ, Eskander A, Urbach DR, Baxter NN. Characterizing the Impact of Procedure Funding on the Covid-19 Generated Procedure Gap in Ontario: A Population-Based Analysis. Ann Surg. 2023 10 01; 278(4):e719-e725. PMID: 36538613.
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Medina S, Ihrie RA, Irish JM. Learning cell identity in immunology, neuroscience, and cancer. Semin Immunopathol. 2023 01; 45(1):3-16. PMID: 36534139.
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Eskander A, Zanchetta C, Coburn N, Enepekides D, Gien LT, Menalo R, Austria G, Linton O, Su-Myat S, Yermakhanova O, Irish J. Cancer surgery cancellation: incidence, outcomes and recovery in a universal health care system. Can J Surg. 2022 Nov-Dec; 65(6):E782-E791. PMID: 36384689.
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Huse K, Bai B, Hilden VI, Bollum LK, Våtsveen TK, Munthe LA, Smeland EB, Irish JM, Wälchli S, Myklebust JH. Mechanism of CD79A and CD79B Support for IgM+ B Cell Fitness through B Cell Receptor Surface Expression. J Immunol. 2022 11 15; 209(10):2042-2053. PMID: 36426942.
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Fu R, Sutradhar R, Li Q, Hanna TP, Chan KKW, Irish JC, Coburn N, Hallet J, Dare A, Singh S, Parmar A, Earle CC, Lapointe-Shaw L, Krzyzanowska MK, Finelli A, Louie AV, Look Hong NJ, Witterick IJ, Mahar A, Gomez D, McIsaac DI, Enepekides D, Urbach DR, Eskander A. Incident Cancer Detection During Multiple Waves of COVID-19: The Tsunami After the Earthquake. J Natl Compr Canc Netw. 2022 11; 20(11):1190-1192. PMID: 36351330.
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Fu R, Sutradhar R, Dare A, Li Q, Hanna TP, Chan KKW, Irish JC, Coburn N, Hallet J, Singh S, Parmar A, Earle CC, Lapointe-Shaw L, Krzyzanowska MK, Finelli A, Louie AV, Witterick IJ, Mahar A, Urbach DR, McIsaac DI, Enepekides D, Look Hong NJ, Eskander A. Cancer Patients First Treated with Chemotherapy: Are They More Likely to Receive Surgery in the Pandemic? Curr Oncol. 2022 10 14; 29(10):7732-7744. PMID: 36290888.
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Balsamo JA, Penton KE, Zhao Z, Hayes MJ, Lima SM, Irish JM, Bachmann BO. An immunogenic cell injury module for the single-cell multiplexed activity metabolomics platform to identify promising anti-cancer natural products. J Biol Chem. 2022 09; 298(9):102300. PMID: 35931117.
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Habbous S, Tai X, Beca JM, Arias J, Raphael MJ, Parmar A, Crespo A, Cheung MC, Eisen A, Eskander A, Singh S, Trudeau M, Gavura S, Dai WF, Irish J, Krzyzanowska M, Lapointe-Shaw L, Naipaul R, Peacock S, Yeung L, Forbes L, Chan KKW. Comparison of Use of Neoadjuvant Systemic Treatment for Breast Cancer and Short-term Outcomes Before vs During the COVID-19 Era in Ontario, Canada. JAMA Netw Open. 2022 08 01; 5(8):e2225118. PMID: 35917122.
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Ghatasheh H, Huang SH, Su J, Xu W, Bratman SV, Cho J, Giuliani M, Hahn E, Hope A, Kim J, O'Sullivan B, Ringash J, Waldron J, Chepeha DB, Irish JC, Goldstein DP, Spreafico A, Tong L, de Almeida JR, Hosni A. Evaluation of risk-tailored individualized selection of radiation therapy target volume for head and neck carcinoma of unknown primary. Radiother Oncol. 2022 10; 175:56-64. PMID: 35905781.
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Kaviany S, Bartkowiak T, Dulek DE, Khan YW, Hayes MJ, Schaefer SG, Ye X, Dahunsi DO, Connelly JA, Irish JM, Rathmell JC. Systems Immunology Analyses of STAT1 Gain-of-Function Immune Phenotypes Reveal Heterogeneous Response to IL-6 and Broad Immunometabolic Roles for STAT1. Immunohorizons. 2022 07 15; 6(7):447-464. PMID: 35840326.
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Eskander A, Noel CW, Griffiths R, Pasternak JD, Higgins K, Urbach D, Goldstein DP, Irish JC, Fu R. Surgeon Thyroidectomy Case Volume Impacts Disease-free Survival in the Management of Thyroid Cancer. Laryngoscope. 2023 05; 133 Suppl 4:S1-S15. PMID: 35796293.
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Kramer KJ, Wilfong EM, Voss K, Barone SM, Shiakolas AR, Raju N, Roe CE, Suryadevara N, Walker LM, Wall SC, Paulo A, Schaefer S, Dahunsi D, Westlake CS, Crowe JE, Carnahan RH, Rathmell JC, Bonami RH, Georgiev IS, Irish JM. Single-cell profiling of the antigen-specific response to BNT162b2 SARS-CoV-2 RNA vaccine. Nat Commun. 2022 06 16; 13(1):3466. PMID: 35710908.
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Sahovaler A, Daly MJ, Chan HHL, Nayak P, Tzelnick S, Arkhangorodsky M, Qiu J, Weersink R, Irish JC, Ferguson P, Wunder JS. Automatic Registration and Error Color Maps to Improve Accuracy for Navigated Bone Tumor Surgery Using Intraoperative Cone-Beam CT. JB JS Open Access. 2022 Apr-Jun; 7(2). PMID: 35540727.
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Sartore L, Pasini C, Pandini S, Dey K, Ferrari M, Taboni S, Chan HHL, Townson J, Viswanathan S, Mathews S, Gilbert RW, Irish JC, Re F, Nicolai P, Russo D. Hybrid Core-Shell Polymer Scaffold for Bone Tissue Regeneration. Int J Mol Sci. 2022 Apr 20; 23(9). PMID: 35562923.
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Id Said B, Ailles L, Karamboulas C, Meens J, Huang SH, Xu W, Keshavarzi S, Bratman SV, Cho BCJ, Giuliani M, Hahn E, Kim J, O'Sullivan B, Ringash J, Waldron J, Spreafico A, de Almeida JR, Chepeha DB, Irish JC, Goldstein DP, Hope A, Hosni A. Development and Validation of an Oral Cavity Cancer Outcomes Prediction Score Incorporating Patient-Derived Xenograft Engraftment. JAMA Otolaryngol Head Neck Surg. 2022 04 01; 148(4):342-349. PMID: 35238880.
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Walker MJ, Wang J, Mazuryk J, Skinner SM, Meggetto O, Ashu E, Habbous S, Nazeri Rad N, Espino-Hernández G, Wood R, Chaudhry M, Vahid S, Gao J, Gallo-Hershberg D, Gutierrez E, Zanchetta C, Langer D, Zwicker V, Rey M, Tammemägi MC, Tinmouth J, Kupets R, Chiarelli AM, Singh S, Warde P, Forbes L, Dobranowski J, Irish J, Rabeneck L. Delivery of Cancer Care in Ontario, Canada, During the First Year of the COVID-19 Pandemic. JAMA Netw Open. 2022 04 01; 5(4):e228855. PMID: 35467731.
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Blasco MA, Noel CW, Truong T, Huang SH, Goldstein DP, Irish JC, Gilbert R, Hosni A, Hope A, O'Sullivan B, Waldron J, Perez-Ordonez B, Weinreb I, Smith SM, Bartlett E, Yu E, de Almeida JR. Radiologic-pathologic correlation of major versus minor extranodal extension in oral cavity cancer. Head Neck. 2022 06; 44(6):1422-1429. PMID: 35315548.
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Parmar A, Eskander A, Sander B, Naimark D, Irish JC, Chan KKW. Impact of cancer surgery slowdowns on patient survival during the COVID-19 pandemic: a microsimulation modelling study. CMAJ. 2022 03 21; 194(11):E408-E414. PMID: 35314440.
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Eskander A, Li Q, Yu J, Hallet J, Coburn N, Dare A, Chan KKW, Singh S, Parmar A, Earle CC, Lapointe-Shaw L, Krzyzanowska MK, Hanna TP, Finelli A, Louie AV, Look-Hong N, Irish JC, Witterick I, Mahar A, Urbach DR, Enepekides D, Sutradhar R. Assessing the Impact of the COVID-19 Pandemic on Emergency Department Use for Patients Undergoing Cancer-Directed Surgeries. Curr Oncol. 2022 03 10; 29(3):1877-1889. PMID: 35323353.
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H L Chan H, Sahovaler A, Daly MJ, Ferrari M, Franz L, Gualtieri T, Tzelnick S, Eu D, Manojlovic-Kolarski M, Berania I, Orzell S, de Almeida JR, Goldstein DP, Nicolai P, Gilbert RW, Irish JC. Projected cutting guides using an augmented reality system to improve surgical margins in maxillectomies: A preclinical study. Oral Oncol. 2022 04; 127:105775. PMID: 35203002.
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Wilfong EM, Bartkowiak T, Vowell KN, Westlake CS, Irish JM, Kendall PL, Crofford LJ, Bonami RH. High-Dimensional Analysis Reveals Distinct Endotypes in Patients With Idiopathic Inflammatory Myopathies. Front Immunol. 2022; 13:756018. PMID: 35371068.
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Sawka AM, Ghai S, Rotstein L, Irish JC, Pasternak JD, Gullane PJ, Monteiro E, Gooden E, Brown DH, Eskander A, Zahedi A, Chung J, Su J, Xu W, Ihekire O, Jones JM, Gafni A, Baxter NN, Goldstein DP. A Quantitative Analysis Examining Patients' Choice of Active Surveillance or Surgery for Managing Low-Risk Papillary Thyroid Cancer. Thyroid. 2022 03; 32(3):255-262. PMID: 35019770.
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Eskander A, Li Q, Yu J, Hallet J, Coburn NG, Dare A, Chan KKW, Singh S, Parmar A, Earle CC, Lapointe-Shaw L, Krzyzanowska MK, Hanna TP, Finelli A, Louie AV, Look Hong N, Irish JC, Witterick IJ, Mahar A, Noel CW, Urbach DR, McIsaac DI, Enepekides D, Sutradhar R. Incident Cancer Detection During the COVID-19 Pandemic. J Natl Compr Canc Netw. 2022 02 01; 20(3):276-284. PMID: 35104788.
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Dahm V, Chan HHL, Daly MJ, Lui JT, Lin VY, Irish J, Chen JM, Le TN. The Feasibility of Eustachian Tube Dilation With a Standard Endovascular Balloon: A Comparative Cadaver Study. Otol Neurotol. 2022 02 01; 43(2):256-262. PMID: 34739430.
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Meghraoui-Kheddar A, Chousterman BG, Guillou N, Barone SM, Granjeaud S, Vallet H, Corneau A, Guessous K, de Roquetaillade C, Boissonnas A, Irish JM, Combadière C. Two New Neutrophil Subsets Define a Discriminating Sepsis Signature. Am J Respir Crit Care Med. 2022 01 01; 205(1):46-59. PMID: 34731593.
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Yeh AC, Varelias A, Reddy A, Barone SM, Olver SD, Chilson K, Onstad LE, Ensbey KS, Henden AS, Samson L, Jaeger CA, Bi T, Dahlman KB, Kim TK, Zhang P, Degli-Esposti MA, Newell EW, Jagasia MH, Irish JM, Lee SJ, Hill GR. CMV exposure drives long-term CD57+ CD4 memory T-cell inflation following allogeneic stem cell transplant. Blood. 2021 12 30; 138(26):2874-2885. PMID: 34115118.
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Le Gallou S, Lhomme F, Irish JM, Mingam A, Pangault C, Monvoisin C, Ferrant J, Azzaoui I, Rossille D, Bouabdallah K, Damaj G, Cartron G, Godmer P, Le Gouill S, Casasnovas RO, Molina TJ, Houot R, Lamy T, Tarte K, Fest T, Roussel M. Nonclassical Monocytes Are Prone to Migrate Into Tumor in Diffuse Large B-Cell Lymphoma. Front Immunol. 2021; 12:755623. PMID: 34975843.
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Ferrari M, Taboni S, Carobbio ALC, Buffoli B, Rampinelli V, Mattavelli D, Schreiber A, Verzeletti V, Ravanelli M, Daly MJ, Chan HHL, Sahovaler A, Franz L, Gualtieri T, Rezzani R, Maroldi R, Signoroni A, Deganello A, Irish JC, Nicolai P. Development of a cadaveric head and neck cancer model and three-dimensional analysis of margins in surgical navigation-aided ablations. Eur J Surg Oncol. 2022 06; 48(6):1235-1242. PMID: 34916084.
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Taboni S, Ferrari M, Daly MJ, Chan HHL, Eu D, Gualtieri T, Jethwa AR, Sahovaler A, Sewell A, Hasan W, Berania I, Qiu J, de Almeida J, Nicolai P, Gilbert RW, Irish JC. Navigation-Guided Transnasal Endoscopic Delineation of the Posterior Margin for Maxillary Sinus Cancers: A Preclinical Study. Front Oncol. 2021; 11:747227. PMID: 34858824.
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Sahovaler A, Chan HHL, Gualtieri T, Daly M, Ferrari M, Vannelli C, Eu D, Manojlovic-Kolarski M, Orzell S, Taboni S, de Almeida JR, Goldstein DP, Deganello A, Nicolai P, Gilbert RW, Irish JC. Augmented Reality and Intraoperative Navigation in Sinonasal Malignancies: A Preclinical Study. Front Oncol. 2021; 11:723509. PMID: 34790568.
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Siu J, Griffiths R, Noel CW, Austin PC, Pasternak J, Urbach D, Monteiro E, Goldstein DP, Irish JC, Sawka AM, Eskander A. Surgical Case Volume has an Impact on Outcomes for Patients with Lateral Neck Disease in Thyroid Cancer. Ann Surg Oncol. 2022 Feb; 29(2):1141-1150. PMID: 34705145.
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Noel CW, Kwinter A, Mifsud M, Ringash J, Waldron J, Chepeha DB, Irish JC, Martino R, Gomes A, Aziza E, de Almeida JR, Goldstein DP. Quantifying Neck Fibrosis and Its Functional Implications: Development of the Neck Fibrosis Scale. Laryngoscope. 2022 05; 132(5):1015-1021. PMID: 34652823.
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Muhanna N, Eu D, Chan HHL, Douglas C, Townson JL, Di Grappa MA, Mohamadi RM, Kelley SO, Bratman SV, Irish JC. Cell-free DNA and circulating tumor cell kinetics in a pre-clinical head and neck Cancer model undergoing radiation therapy. BMC Cancer. 2021 Oct 02; 21(1):1075. PMID: 34600526.
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Mukkala AN, Song JB, Lee M, Boasie A, Irish J, Finelli A, Wei AC. A systematic review and meta-analysis of unplanned hospital visits and re-admissions following radical prostatectomy for prostate cancer. Can Urol Assoc J. 2021 Oct; 15(10):E531-E544. PMID: 33750517.
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Muhanna N, Douglas CM, Chan HHL, Daly MJ, Townson JL, Ferrari M, Eu D, Akens M, Chen J, Zheng G, Irish JC. Rabbit VX2 head and neck squamous cell models for translational head and neck theranostic technology development. Clin Transl Med. 2021 10; 11(10):e550. PMID: 34709737.
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Oliva M, Chepeha D, Araujo DV, Diaz-Mejia JJ, Olson P, Prawira A, Spreafico A, Bratman SV, Shek T, de Almeida J, R Hansen A, Hope A, Goldstein D, Weinreb I, Smith S, Perez-Ordoñez B, Irish J, Torti D, Bruce JP, Wang BX, Fortuna A, Pugh TJ, Der-Torossian H, Shazer R, Attanasio N, Au Q, Tin A, Feeney J, Sethi H, Aleshin A, Chen I, Siu L. Antitumor immune effects of preoperative sitravatinib and nivolumab in oral cavity cancer: SNOW window-of-opportunity study. J Immunother Cancer. 2021 10; 9(10). PMID: 34599023.
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Orzell S, Verhaaren BFJ, Grewal R, Sklar M, Irish JC, Gilbert R, Brown D, Gullane P, de Almeida JR, Yu E, Su J, Xu W, Alibhai SMH, Goldstein DP. Evaluation of Sarcopenia in Older Patients Undergoing Head and Neck Cancer Surgery. Laryngoscope. 2022 02; 132(2):356-363. PMID: 34383321.
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Noel CW, Griffiths R, Siu J, Forner D, Urbach D, Freeman J, Goldstein DP, Irish JC, Higgins KM, Devon K, Pasternak JD, Eskander A. A Population-Based Analysis of Outpatient Thyroidectomy: Safe and Under-Utilized. Laryngoscope. 2021 11; 131(11):2625-2633. PMID: 34378810.
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Barone SM, Paul AG, Muehling LM, Lannigan JA, Kwok WW, Turner RB, Woodfolk JA, Irish JM. Unsupervised machine learning reveals key immune cell subsets in COVID-19, rhinovirus infection, and cancer therapy. Elife. 2021 08 05; 10. PMID: 34350827.
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Ramsey HE, Stengel K, Pino JC, Johnston G, Childress M, Gorska AE, Arrate PM, Fuller L, Villaume M, Fischer MA, Ferrell PB, Roe CE, Zou J, Lubbock ALR, Stubbs M, Zinkel S, Irish JM, Lopez CF, Hiebert S, Savona MR. Selective Inhibition of JAK1 Primes STAT5-Driven Human Leukemia Cells for ATRA-Induced Differentiation. Target Oncol. 2021 09; 16(5):663-674. PMID: 34324169.
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Senosain MF, Zou Y, Novitskaya T, Vasiukov G, Balar AB, Rowe DJ, Doxie DB, Lehman JM, Eisenberg R, Maldonado F, Zijlstra A, Novitskiy SV, Irish JM, Massion PP. HLA-DR cancer cells expression correlates with T cell infiltration and is enriched in lung adenocarcinoma with indolent behavior. Sci Rep. 2021 Jul 13; 11(1):14424. PMID: 34257356.
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Chiu K, Hosni A, Huang SH, Tong L, Xu W, Lu L, Bayley A, Bratman S, Cho J, Giuliani M, Kim J, Ringash J, Waldron J, Spreafico A, Irish J, Gilbert R, Gullane P, Goldstein D, O'Sullivan B, Hope A. The Potential Impact and Usability of the Eighth Edition TNM Staging Classification in Oral Cavity Cancer. Clin Oncol (R Coll Radiol). 2021 10; 33(10):e442-e449. PMID: 34261594.
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Davies JC, Chan HHL, Yao CMKL, Ziai H, Dixon PR, Chepeha DB, Goldstein DP, de Almeida JR, Gilbert RW, Irish JC. Association of Plate Contouring With Hardware Complications Following Mandibular Reconstruction. Laryngoscope. 2022 01; 132(1):61-66. PMID: 34165789.
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Reisman BJ, Barone SM, Bachmann BO, Irish JM. DebarcodeR increases fluorescent cell barcoding capacity and accuracy. Cytometry A. 2021 09; 99(9):946-953. PMID: 33960644.
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Noel CW, Sutradhar R, Zhao H, Delibasic V, Forner D, Irish JC, Kim J, Husain Z, Mahar A, Karam I, Enepekides DJ, Chan KKW, Singh S, Hallet J, Coburn NG, Eskander A. Reply to K. Yokoyama et al. J Clin Oncol. 2021 07 20; 39(21):2417-2419. PMID: 33950700.
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Chan HHL, Haerle SK, Daly MJ, Zheng J, Philp L, Ferrari M, Douglas CM, Irish JC. An integrated augmented reality surgical navigation platform using multi-modality imaging for guidance. PLoS One. 2021; 16(4):e0250558. PMID: 33930063.
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Sahovaler A, Ziai H, Cardemil F, Huang SH, Su J, Goldstein DP, Gilbert R, Hosni A, Hope A, Waldron J, Spreafico A, Monteiro E, Witterick I, Irish J, Gullane P, Xu W, O'Sullivan B, de Almeida JR. Importance of Margins, Radiotherapy, and Systemic Therapy in Mucosal Melanoma of the Head and Neck. Laryngoscope. 2021 10; 131(10):2269-2276. PMID: 33856051.
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Sahovaler A, Chan HHL, Ferrari M, Gualtieri T, Zhang C, Taboni S, Irish JC, Gilbert RW. Objective evaluation of orbito-zygomatic reconstruction with scapular tip free flaps to restore facial projection and orbital volume. Oral Oncol. 2021 06; 117:105268. PMID: 33848724.
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Eu D, Daly MJ, Irish JC. Imaging-based navigation technologies in head and neck surgery. Curr Opin Otolaryngol Head Neck Surg. 2021 Apr 01; 29(2):149-155. PMID: 33394735.
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Hamour AF, Yang W, Lee JJW, Wu V, Ziai H, Singh P, Eskander A, Sahovaler A, Higgins K, Witterick IJ, Vescan A, Freeman J, de Almeida JR, Goldstein D, Gilbert R, Chepeha D, Irish J, Enepekides D, Monteiro E. Association of the Implementation of a Standardized Thyroid Ultrasonography Reporting Program With Documentation of Nodule Characteristics. JAMA Otolaryngol Head Neck Surg. 2021 04 01; 147(4):343-349. PMID: 33570552.
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Gagliardi AR, Yip CYY, Irish J, Wright FC, Rubin B, Ross H, Green R, Abbey S, McAndrews MP, Stewart DE. The psychological burden of waiting for procedures and patient-centred strategies that could support the mental health of wait-listed patients and caregivers during the COVID-19 pandemic: A scoping review. Health Expect. 2021 06; 24(3):978-990. PMID: 33769657.
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Sternheim A, Rotman D, Nayak P, Arkhangorodsky M, Daly MJ, Irish JC, Ferguson PC, Wunder JS. Computer-assisted surgical planning of complex bone tumor resections improves negative margin outcomes in a sawbones model. Int J Comput Assist Radiol Surg. 2021 Apr; 16(4):695-701. PMID: 33725339.
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Milkovich J, Hanna T, Nessim C, Petrella TM, Weatherhead L, Chan AW, Irish JC, Murray C, Bannerman G, Holloway C, Forster K, Pazzano L, Wright FC. Restructuring Skin Cancer Care in Ontario: A Provincial Plan. Curr Oncol. 2021 03 12; 28(2):1183-1196. PMID: 33809399.
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Levine LS, Hiam-Galvez KJ, Marquez DM, Tenvooren I, Madden MZ, Contreras DC, Dahunsi DO, Irish JM, Oluwole OO, Rathmell JC, Spitzer MH. Single-cell analysis by mass cytometry reveals metabolic states of early-activated CD8+ T cells during the primary immune response. Immunity. 2021 04 13; 54(4):829-844.e5. PMID: 33705706.
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Eskander A, Li Q, Hallet J, Coburn N, Hanna TP, Irish J, Sutradhar R. Access to Cancer Surgery in a Universal Health Care System During the COVID-19 Pandemic. JAMA Netw Open. 2021 03 01; 4(3):e211104. PMID: 33704472.
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Healey DCC, Cephus JY, Barone SM, Chowdhury NU, Dahunsi DO, Madden MZ, Ye X, Yu X, Olszewski K, Young K, Gerriets VA, Siska PJ, Dworski R, Hemler J, Locasale JW, Poyurovsky MV, Peebles RS, Irish JM, Newcomb DC, Rathmell JC. Targeting In Vivo Metabolic Vulnerabilities of Th2 and Th17 Cells Reduces Airway Inflammation. J Immunol. 2021 03 15; 206(6):1127-1139. PMID: 33558372.
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Ferrant J, Lhomme F, Le Gallou S, Irish JM, Roussel M. Circulating Myeloid Regulatory Cells: Promising Biomarkers in B-Cell Lymphomas. Front Immunol. 2020; 11:623993. PMID: 33603754.
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Wang J, Vahid S, Eberg M, Milroy S, Milkovich J, Wright FC, Hunter A, Kalladeen R, Zanchetta C, Wijeysundera HC, Irish J. CMAJ. 2021 01 11; 193(2):E63-E73. PMID: 33431552.
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Noel CW, Sutradhar R, Zhao H, Delibasic V, Forner D, Irish JC, Kim J, Husain Z, Mahar A, Karam I, Enepekides DJ, Chan KKW, Singh S, Hallet J, Coburn NG, Eskander A. Patient-Reported Symptom Burden as a Predictor of Emergency Department Use and Unplanned Hospitalization in Head and Neck Cancer: A Longitudinal Population-Based Study. J Clin Oncol. 2021 02 20; 39(6):675-684. PMID: 33405964.
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Sahovaler A, Ferrari M, Chan H, Ziai H, Gilbert R, Irish J. Comparing Contour Restoration of Mandibular Body Defects With Fibula, Iliac Crest, and Scapular Tip Flaps: A Conformance Virtual Study. J Oral Maxillofac Surg. 2021 06; 79(6):1345-1354. PMID: 33508237.
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Forner D, Hong P, Corsten M, Rac VE, Martino R, Shuman AG, Chepeha DB, Sawka AM, de Almeida JR, Irish JC, Brown DH, Taylor SM, Gullane PJ, Trites JR, Gilbert R, Rigby MH, Ringash J, Goldstein D. Needs assessment for a decision support tool in oral cancer requiring major resection and reconstruction: a mixed-methods study protocol. BMJ Open. 2020 11 23; 10(11):e036969. PMID: 33234615.
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Muhanna N, Eu D, Chan HH, Daly M, Fricke IB, Douglas CM, Townson JL, Zheng J, Allen C, Jaffray DA, Irish JC. Assessment of a liposomal CT/optical contrast agent for image-guided head and neck surgery. Nanomedicine. 2021 02; 32:102327. PMID: 33220507.
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Barone SM, Paul AGA, Muehling LM, Lannigan JA, Kwok WW, Turner RB, Woodfolk JA, Irish JM. Unsupervised machine learning reveals key immune cell subsets in COVID-19, rhinovirus infection, and cancer therapy. bioRxiv. 2020 Nov 04. PMID: 32766581.
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Noel CW, Forner D, Wu V, Enepekides D, Irish JC, Husain Z, Chan KKW, Hallet J, Coburn N, Eskander A. Predictors of surgical readmission, unplanned hospitalization and emergency department use in head and neck oncology: A systematic review. Oral Oncol. 2020 12; 111:105039. PMID: 33141060.
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Ziai H, Yu E, Weinreb I, Perez-Ordonez B, Yao CMKL, Xu W, Yang D, Witterick IJ, Monteiro E, Gilbert RW, Irish JC, Gullane PJ, Goldstein DP, Ringash J, Bayley A, de Almeida JR. Regional Recurrences and Hyams Grade in Esthesioneuroblastoma. J Neurol Surg B Skull Base. 2021 Dec; 82(6):608-614. PMID: 34745827.
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Muhanna N, Chan HHL, Douglas CM, Daly MJ, Jaidka A, Eu D, Bernstein J, Townson JL, Irish JC. Sentinel lymph node mapping using ICG fluorescence and cone beam CT - a feasibility study in a rabbit model of oral cancer. BMC Med Imaging. 2020 09 14; 20(1):106. PMID: 32928138.
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Chattopadhyay PK, Filby A, Jellison ER, Ferrari G, Green C, Cherian S, Irish J, Litwin V. A Cytometrist's Guide to Coordinating and Performing Effective COVID-19 Research. Cytometry A. 2021 01; 99(1):11-18. PMID: 32881296.
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Wang J, Vahid S, Eberg M, Milroy S, Milkovich J, Wright FC, Hunter A, Kalladeen R, Zanchetta C, Wijeysundera HC, Irish J. Clearing the surgical backlog caused by COVID-19 in Ontario: a time series modelling study. CMAJ. 2020 11 02; 192(44):E1347-E1356. PMID: 32873541.
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Hosni A, Chiu K, Huang SH, Xu W, Huang J, Bayley A, Bratman SV, Cho J, Giuliani M, Kim J, O'Sullivan B, Ringash J, Waldron J, Spreafico A, de Almeida JR, Monteiro E, Witterick I, Chepeha DB, Gilbert RW, Irish JC, Goldstein DP, Hope A. Non-operative management for oral cavity carcinoma: Definitive radiation therapy as a potential alternative treatment approach. Radiother Oncol. 2021 01; 154:70-75. PMID: 32861702.
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Douglas CM, Jethwa AR, Hasan W, Liu A, Gilbert R, Goldstein D, De Almedia J, Lipton J, Irish JC. Long-term survival of head and neck squamous cell carcinoma after bone marrow transplant. Head Neck. 2020 11; 42(11):3389-3395. PMID: 32820585.
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Davies JC, Chan HHL, Gilbert RW, Irish JC. Nasal Endoscopy During the COVID-19 Pandemic: Mitigating Risk with 3D Printed Masks. Laryngoscope. 2020 11; 130(11):2561-2563. PMID: 32716050.
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Beckermann KE, Hongo R, Ye X, Young K, Carbonell K, Healey DCC, Siska PJ, Barone S, Roe CE, Smith CC, Vincent BG, Mason FM, Irish JM, Rathmell WK, Rathmell JC. CD28 costimulation drives tumor-infiltrating T cell glycolysis to promote inflammation. JCI Insight. 2020 08 20; 5(16). PMID: 32814710.
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Lim SP, Costantini B, Mian SA, Perez Abellan P, Gandhi S, Martinez Llordella M, Lozano JJ, Antunes Dos Reis R, Povoleri GAM, Mourikis TP, Abarrategi A, Ariza-McNaughton L, Heck S, Irish JM, Lombardi G, Marsh JCW, Bonnet D, Kordasti S, Mufti GJ. Treg sensitivity to FasL and relative IL-2 deprivation drive idiopathic aplastic anemia immune dysfunction. Blood. 2020 08 13; 136(7):885-897. PMID: 32294156.
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Goldstein DP, Ralph G, de Almeida JR, Jethwa AR, Irish J, Chepeha DB, Brown D, Gullane P, Waldron J, Aziza E, Durkin L. Tracheoesophageal voice prosthesis management in laryngectomy patients during the COVID-19 pandemic. J Otolaryngol Head Neck Surg. 2020 Aug 10; 49(1):59. PMID: 32778168.
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Woolman M, Qiu J, Kuzan-Fischer CM, Ferry I, Dara D, Katz L, Daud F, Wu M, Ventura M, Bernards N, Chan H, Fricke I, Zaidi M, Wouters BG, Rutka JT, Das S, Irish J, Weersink R, Ginsberg HJ, Jaffray DA, Zarrine-Afsar A. In situ tissue pathology from spatially encoded mass spectrometry classifiers visualized in real time through augmented reality. Chem Sci. 2020 Jul 23; 11(33):8723-8735. PMID: 34123126.
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de Almeida JR, Truong T, Khan NM, Su JS, Irish J, Gilbert R, Goldstein D, Huang SH, O'Sullivan B, Hosni A, Hope A, Waldron J, Hansen AR, Spreafico A, Siu LL, Perez-Ordonez B, Xu W, Weinreb I. Treatment implications of postoperative chemoradiotherapy for squamous cell carcinoma of the oral cavity with minor and major extranodal extension. Oral Oncol. 2020 11; 110:104845. PMID: 32615441.
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Leelatian N, Sinnaeve J, Mistry AM, Barone SM, Brockman AA, Diggins KE, Greenplate AR, Weaver KD, Thompson RC, Chambless LB, Mobley BC, Ihrie RA, Irish JM. Unsupervised machine learning reveals risk stratifying glioblastoma tumor cells. Elife. 2020 06 23; 9. PMID: 32573435.
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Huang SH, O'Sullivan B, Su J, Ringash J, Bratman SV, Kim J, Hosni A, Bayley A, Cho J, Giuliani M, Hope A, Spreafico A, Hansen AR, Siu LL, Gilbert R, Irish JC, Goldstein D, de Almeida J, Tong L, Xu W, Waldron J. Hypofractionated radiotherapy alone with 2.4 Gy per fraction for head and neck cancer during the COVID-19 pandemic: The Princess Margaret experience and proposal. Cancer. 2020 08 01; 126(15):3426-3437. PMID: 32478895.
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Irish J, Kim J, Waldron J, Wei AC, Winquist E, Yoo J, Boasie A, Brouwers M, Meertens E, McNair S, Walker-Dilks C. Organizational guidance for the care of patients with head-and-neck cancer in Ontario. Curr Oncol. 2020 04; 27(2):e115-e122. PMID: 32489261.
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Wu V, Noel CW, Forner D, Zhang ZJ, Higgins KM, Enepekides DJ, Lee JM, Witterick IJ, Kim JJ, Waldron JN, Irish JC, Hua QQ, Eskander A. Considerations for head and neck oncology practices during the coronavirus disease 2019 (COVID-19) pandemic: Wuhan and Toronto experience. Head Neck. 2020 06; 42(6):1202-1208. PMID: 32338807.
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Ferrer-Font L, Mayer JU, Old S, Hermans IF, Irish J, Price KM. High-Dimensional Data Analysis Algorithms Yield Comparable Results for Mass Cytometry and Spectral Flow Cytometry Data. Cytometry A. 2020 08; 97(8):824-831. PMID: 32293794.
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Sawka AM, Ghai S, Yoannidis T, Rotstein L, Gullane PJ, Gilbert RW, Pasternak JD, Brown DH, Eskander A, Almeida JR, Irish JC, Higgins K, Enepekides DJ, Monteiro E, Banerjee A, Shah M, Gooden E, Zahedi A, Korman M, Ezzat S, Jones JM, Rac VE, Tomlinson G, Stanimirovic A, Gafni A, Baxter NN, Goldstein DP. A Prospective Mixed-Methods Study of Decision-Making on Surgery or Active Surveillance for Low-Risk Papillary Thyroid Cancer. Thyroid. 2020 07; 30(7):999-1007. PMID: 32126932.
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Oliva M, Huang SH, Taylor R, Su J, Xu W, Hansen AR, Jang R, Bayley A, Hosni A, Giuliani M, Ringash J, Bratman SV, Cho J, Irish J, Waldron J, Weinreb I, Kim J, O'Sullivan B, Siu LL, Spreafico A. Impact of cumulative cisplatin dose and adjuvant chemotherapy in locally-advanced nasopharyngeal carcinoma treated with definitive chemoradiotherapy. Oral Oncol. 2020 06; 105:104666. PMID: 32272384.
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Roe CE, Hayes MJ, Barone SM, Irish JM. Training Novices in Generation and Analysis of High-Dimensional Human Cell Phospho-Flow Cytometry Data. Curr Protoc Cytom. 2020 03; 93(1):e71. PMID: 32250555.
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Muhanna N, Douglas CM, Daly MJ, Chan HHL, Weersink R, Townson J, Monteiro E, Yu E, Weimer E, Kucharczyk W, Jaffray DA, Irish JC, de Almeida JR. Evaluating an Image-Guided Operating Room with Cone Beam CT for Skull Base Surgery. J Neurol Surg B Skull Base. 2021 Jul; 82(Suppl 3):e306-e314. PMID: 34306954.
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Reis PP, Tokar T, Goswami RS, Xuan Y, Sukhai M, Seneda AL, Móz LES, Perez-Ordonez B, Simpson C, Goldstein D, Brown D, Gilbert R, Gullane P, Irish J, Jurisica I, Kamel-Reid S. A 4-gene signature from histologically normal surgical margins predicts local recurrence in patients with oral carcinoma: clinical validation. Sci Rep. 2020 02 03; 10(1):1713. PMID: 32015424.
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Muhanna N, Chan HHL, Townson JL, Jin CS, Ding L, Valic MS, Douglas CM, MacLaughlin CM, Chen J, Zheng G, Irish JC. Photodynamic therapy enables tumor-specific ablation in preclinical models of thyroid cancer. Endocr Relat Cancer. 2020 02; 27(2):41-53. PMID: 31751308.
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Roussel M, Lhomme F, Roe CE, Bartkowiak T, Gravelle P, Laurent C, Fest T, Irish JM. Mass cytometry defines distinct immune profile in germinal center B-cell lymphomas. Cancer Immunol Immunother. 2020 Mar; 69(3):407-420. PMID: 31919622.
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Czechowska K, Lannigan J, Aghaeepour N, Back JB, Begum J, Behbehani G, Bispo C, Bitoun D, Fernández AB, Boova ST, Brinkman RR, Ciccolella CO, Cotleur B, Davies D, Dela Cruz GV, Del Rio-Guerra R, Des Lauriers-Cox AM, Douagi I, Dumrese C, Bonilla Escobar DL, Estevam J, Ewald C, Fossum A, Gaudillière B, Green C, Groves C, Hall C, Haque Y, Hedrick MN, Hogg K, Hsieh EWY, Irish J, Lederer J, Leipold M, Lewis-Tuffin LJ, Litwin V, Lopez P, Nasdala I, Nedbal J, Ohlsson-Wilhelm BM, Price KM, Rahman AH, Rayanki R, Rieger AM, Robinson JP, Shapiro H, Sun YS, Tang VA, Tesfa L, Telford WG, Walker R, Welsh JA, Wheeler P, Tárnok A. Cyt-Geist: Current and Future Challenges in Cytometry: Reports of the CYTO 2019 Conference Workshops. Cytometry A. 2019 12; 95(12):1236-1274. PMID: 31833655.
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Thomas CM, Sklar MC, Su J, Xu W, de Almeida JR, Gullane P, Gilbert R, Brown D, Irish J, Alibhai SMH, Goldstein DP. Evaluation of Older Age and Frailty as Factors Associated With Depression and Postoperative Decision Regret in Patients Undergoing Major Head and Neck Surgery. JAMA Otolaryngol Head Neck Surg. 2019 12 01; 145(12):1170-1178. PMID: 31621812.
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Nateghifard K, Low D, Awofala L, Srikanthan D, Kuthubutheen J, Daly M, Chan H, Irish J, Chen J, Lin V, Le TN. Cone beam CT for perioperative imaging in hearing preservation Cochlear implantation - a human cadaveric study. J Otolaryngol Head Neck Surg. 2019 Nov 21; 48(1):65. PMID: 31753027.
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Eskander A, de Almeida JR, Irish JC. Acute Upper Airway Obstruction. N Engl J Med. 2019 Nov 14; 381(20):1940-1949. PMID: 31722154.
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Ferrari M, Daly MJ, Douglas CM, Chan HHL, Qiu J, Deganello A, Taboni S, Thomas CM, Sahovaler A, Jethwa AR, Hasan W, Nicolai P, Gilbert RW, Irish JC. Navigation-guided osteotomies improve margin delineation in tumors involving the sinonasal area: A preclinical study. Oral Oncol. 2019 12; 99:104463. PMID: 31683173.
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Hall SF, Irish JC, Griffiths RJ, Whitehead M. Explaining the Variation in Surgical Practice for Differentiated Thyroid Cancer in Ontario, Canada. JAMA Otolaryngol Head Neck Surg. 2019 Oct 01; 145(10):949-954. PMID: 31465105.
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Philp L, Chan H, Rouzbahman M, Rostami A, Ding L, Bratman SV, Akens MK, Irish JC, Bernardini MQ, Zheng G. An Orthotopic Endometrial Cancer Model with Retroperitoneal Lymphadenopathy Made From In Vivo Propagated and Cultured VX2 Cells. J Vis Exp. 2019 09 12; (151). PMID: 31566617.
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Jozaghi Y, Chan HHL, Davies JC, Irish JC. Establishing Orbital Floor Symmetry to Support Mirror Imaging in Computer-Aided Reconstruction of the Orbital Floor. J Craniofac Surg. 2019 Sep; 30(6):1888-1890. PMID: 31756877.
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Grasl S, Janik S, Grasl MC, Pammer J, Formanek M, Weinreb I, Perez-Ordonez B, Hope A, Hosni A, de Almeida JR, Irish J, Gilbert R, Goldstein DP, Erovic BM. Nodal Metastases in Acinic Cell Carcinoma of the Parotid Gland. J Clin Med. 2019 Aug 27; 8(9). PMID: 31461946.
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Goldstein DP, Sklar MC, de Almeida JR, Gilbert R, Gullane P, Irish J, Brown D, Higgins K, Enepekides D, Xu W, Su J, Alibhai SMH. Frailty as a predictor of outcomes in patients undergoing head and neck cancer surgery. Laryngoscope. 2020 05; 130(5):E340-E345. PMID: 31418866.
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de Almeida JR, Yao CMKL, Ziai H, Staibano P, Huang SH, Hosni A, Hope A, Bratman SV, Monteiro E, Gilbert RW, Brown DH, Gullane PJ, Irish JC, Su J, Xu W, Goldstein DP. Postoperative wound infections, neutrophil-to-lymphocyte ratio, and cancer recurrence in patients with oral cavity cancer undergoing surgical resection. Oral Oncol. 2019 10; 97:23-30. PMID: 31421467.
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Erovic BM, Goldstein DP, Asa SL, Janik S, Mete O, Irish JC. VEGFR-2 is downregulated in sestamibi-negative parathyroid adenomas. Head Neck. 2019 10; 41(10):3564-3569. PMID: 31291025.
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Muhanna N, Douglas CM, Daly MJ, Chan HHL, Weersink R, Qiu J, Townson J, de Almeida JR, Goldstein D, Gilbert R, Yu E, Kucharczyk W, Jaffray DA, Irish JC. The image-guided operating room-Utility and impact on surgeon's performance in the head and neck surgery. Head Neck. 2019 09; 41(9):3372-3382. PMID: 31287216.
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Hasan W, Daly MJ, Chan HHL, Qiu J, Irish JC. Intraoperative cone-beam CT-guided osteotomy navigation in mandible and maxilla surgery. Laryngoscope. 2020 05; 130(5):1166-1172. PMID: 31112320.
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Groome PA, Webber C, Whitehead M, Moineddin R, Grunfeld E, Eisen A, Gilbert J, Holloway C, Irish JC, Langley H. Determining the Cancer Diagnostic Interval Using Administrative Health Care Data in a Breast Cancer Cohort. JCO Clin Cancer Inform. 2019 05; 3:1-10. PMID: 31112418.
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Eskander A, Hall SF, Manduch M, Griffiths R, Irish JC. Reply to Letter to the Editor Regarding "The Importance of Diagnosing Noninvasive Follicular Thyroid Neoplasm with Papillary-Like Nuclear Features (NIFTP) Based on the Defined Criteria". Ann Surg Oncol. 2019 07; 26(7):2308-2310. PMID: 30993411.
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Rushing GV, Brockman AA, Bollig MK, Leelatian N, Mobley BC, Irish JM, Ess KC, Fu C, Ihrie RA. Location-dependent maintenance of intrinsic susceptibility to mTORC1-driven tumorigenesis. Life Sci Alliance. 2019 04; 2(2). PMID: 30910807.
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Huse K, Wogsland CE, Polikowsky HG, Diggins KE, Smeland EB, Myklebust JH, Irish JM. Human Germinal Center B Cells Differ from Naïve and Memory B Cells in CD40 Expression and CD40L-Induced Signaling Response. Cytometry A. 2019 04; 95(4):442-449. PMID: 30838773.
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Hoetzenecker K, Chan HHL, Frommlet F, Schweiger T, Keshavjee S, Waddell TK, Klepetko W, Irish JC, Yasufuku K. 3D Models in the Diagnosis of Subglottic Airway Stenosis. Ann Thorac Surg. 2019 06; 107(6):1860-1865. PMID: 30825452.
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Hosni A, Huang SH, Chiu K, Xu W, Su J, Lu L, Bayley A, Bratman SV, Cho J, Giuliani M, Kim J, O'Sullivan B, Ringash J, Waldron J, Spreafico A, de Almeida JR, Chepeha DB, Irish JC, Goldstein DP, Hope A. Validation of distant metastases risk-groups in oral cavity squamous cell carcinoma patients treated with postoperative intensity-modulated radiotherapy. Radiother Oncol. 2019 05; 134:10-16. PMID: 31005202.
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Hong CJ, Giannopoulos AA, Hong BY, Witterick IJ, Irish JC, Lee J, Vescan A, Mitsouras D, Dang W, Campisi P, de Almeida JR, Monteiro E. Clinical applications of three-dimensional printing in otolaryngology-head and neck surgery: A systematic review. Laryngoscope. 2019 09; 129(9):2045-2052. PMID: 30698840.
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Figueiró-Filho EA, Horgan RP, Muhanna N, Parrish J, Irish JC, Maxwell CV. Obstetrical Outcomes of Head and Neck (Nonthyroid) Cancers: A 27-Year Retrospective Series and Literature Review. AJP Rep. 2019 Jan; 9(1):e15-e22. PMID: 30701125.
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Eskander A, Hall SF, Manduch M, Griffiths R, Irish JC. A Population-Based Study on NIFTP Incidence and Survival: Is NIFTP Really a "Benign" Disease? Ann Surg Oncol. 2019 May; 26(5):1376-1384. PMID: 30690683.
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Hu HP, Chan H, Ujiie H, Bernards N, Fujino K, Irish JC, Zheng J, Yasufuku K. Nanoparticle-based CT visualization of pulmonary vasculature for minimally-invasive thoracic surgery planning. PLoS One. 2019; 14(1):e0209501. PMID: 30653521.
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Mistry AM, Greenplate AR, Ihrie RA, Irish JM. Beyond the message: advantages of snapshot proteomics with single-cell mass cytometry in solid tumors. FEBS J. 2019 04; 286(8):1523-1539. PMID: 30549207.
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Roussel M, Bartkowiak T, Irish JM. Picturing Polarized Myeloid Phagocytes and Regulatory Cells by Mass Cytometry. Methods Mol Biol. 2019; 1989:217-226. PMID: 31077108.
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Davies JC, Chan HHL, Jozaghi Y, Goldstein DP, Irish JC. Analysis of simulated mandibular reconstruction using a segmental mirroring technique. J Craniomaxillofac Surg. 2019 Mar; 47(3):468-472. PMID: 30661926.
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Davies JC, Chan HHL, Yao CMKL, Cusimano MD, Irish JC, Lee JM. Quantitative Analysis of Surgical Working Space During Endoscopic Skull Base Surgery. J Neurol Surg B Skull Base. 2019 Oct; 80(5):469-473. PMID: 31534887.
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Greenplate AR, McClanahan DD, Oberholtzer BK, Doxie DB, Roe CE, Diggins KE, Leelatian N, Rasmussen ML, Kelley MC, Gama V, Siska PJ, Rathmell JC, Ferrell PB, Johnson DB, Irish JM. Computational Immune Monitoring Reveals Abnormal Double-Negative T Cells Present across Human Tumor Types. Cancer Immunol Res. 2019 01; 7(1):86-99. PMID: 30413431.
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Irish JC. The 2018 American Head and Neck Society Presidential Address-Reflections. JAMA Otolaryngol Head Neck Surg. 2018 11 01; 144(11):1077-1080. PMID: 30286218.
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Zanchetta C, Irish JC, Waddell JP. The Road to Improving Access to Surgical Specialist Consultations: Ontario's Experience with Wait 1 Wait Time Data. Healthc Q. 2018 Oct; 21(3):42-50. PMID: 30741155.
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Hosni A, Huang SH, Chiu K, Xu W, Su J, Bayley A, Bratman SV, Cho J, Giuliani M, Kim J, O'Sullivan B, Ringash J, Waldron J, Spreafico A, Yu E, de Almeida JR, Monteiro E, Chepeha DB, Irish JC, Goldstein DP, Hope A. Predictors of Early Recurrence Prior to Planned Postoperative Radiation Therapy for Oral Cavity Squamous Cell Carcinoma and Outcomes Following Salvage Intensified Radiation Therapy. Int J Radiat Oncol Biol Phys. 2019 02 01; 103(2):363-373. PMID: 30244160.
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Gandelman JS, Byrne MT, Mistry AM, Polikowsky HG, Diggins KE, Chen H, Lee SJ, Arora M, Cutler C, Flowers M, Pidala J, Irish JM, Jagasia MH. Machine learning reveals chronic graft-versus-host disease phenotypes and stratifies survival after stem cell transplant for hematologic malignancies. Haematologica. 2019 01; 104(1):189-196. PMID: 30237265.
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Johnson-Obaseki S, Caulley L, Corsten M, Liu G, Dimitroulakos J, Goldstein D, Irish J, Rider J. C-reactive Protein in HPV-Positive and HPV-Negative Oropharyngeal Cancer. Otolaryngol Head Neck Surg. 2019 03; 160(3):494-501. PMID: 30226795.
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Weimar EAM, Huang SH, Lu L, O'Sullivan B, Perez-Ordonez B, Weinreb I, Hope A, Tong L, Goldstein D, Irish J, de Almeida JR, Bratman S, Xu W, Yu E. Radiologic-Pathologic Correlation of Tumor Thickness and Its Prognostic Importance in Squamous Cell Carcinoma of the Oral Cavity: Implications for the Eighth Edition Tumor, Node, Metastasis Classification. AJNR Am J Neuroradiol. 2018 10; 39(10):1896-1902. PMID: 30166432.
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Lee CY, Chan H, Ujiie H, Fujino K, Kinoshita T, Irish JC, Yasufuku K. Novel Thoracoscopic Navigation System With Augmented Real-Time Image Guidance for Chest Wall Tumors. Ann Thorac Surg. 2018 11; 106(5):1468-1475. PMID: 30120940.
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Doxie DB, Greenplate AR, Gandelman JS, Diggins KE, Roe CE, Dahlman KB, Sosman JA, Kelley MC, Irish JM. BRAF and MEK inhibitor therapy eliminates Nestin-expressing melanoma cells in human tumors. Pigment Cell Melanoma Res. 2018 11; 31(6):708-719. PMID: 29778085.
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Eskander A, Krzyzanowska MK, Fischer HD, Liu N, Austin PC, Irish JC, Enepekides DJ, Lee J, Gutierrez E, Lockhart E, Raphael M, Singh S. Emergency department visits and unplanned hospitalizations in the treatment period for head and neck cancer patients treated with curative intent: A population-based analysis. Oral Oncol. 2018 08; 83:107-114. PMID: 30098764.
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Horowitz G, Hosni A, Yu E, Xu W, Lu L, Au M, Dixon PR, Brown D, Chepeha DB, Gilbert RW, Goldstein DP, Gullane PJ, Irish JC, Bayley A, Cho J, Giuliani M, Huang SH, Hope A, Kim J, O'Sullivan B, Ringash J, Waldron J, Weinreb I, Perez-Ordonez B, Bratman SV, de Almeida JR. Prevalence, prognosis, and treatment implications of retropharyngeal nodes in unknown primary head and neck carcinoma. Oral Oncol. 2018 07; 82:162-167. PMID: 29909891.
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Almulla A, Noel CW, Lu L, Xu W, O'Sullivan B, Goldstein DP, Hope A, Perez-Ordonez B, Weinreb I, Irish J, Gullane P, Chepeha D, Tong L, Yu E, Huang SH. Radiologic-Pathologic Correlation of Extranodal Extension in Patients With Squamous Cell Carcinoma of the Oral Cavity: Implications for Future Editions of the TNM Classification. Int J Radiat Oncol Biol Phys. 2018 11 15; 102(4):698-708. PMID: 29970315.
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Sternheim A, Kashigar A, Daly M, Chan H, Qiu J, Weersink R, Jaffray D, Irish JC, Ferguson PC, Wunder JS. Cone-Beam Computed Tomography-Guided Navigation in Complex Osteotomies Improves Accuracy at All Competence Levels: A Study Assessing Accuracy and Reproducibility of Joint-Sparing Bone Cuts. J Bone Joint Surg Am. 2018 May 16; 100(10):e67. PMID: 29762285.
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Mah K, Lebel S, Irish J, Bezjak A, Payne AYM, Devins GM. A two-dimensional model of disrupted body integrity: initial evaluation in head and neck cancer. Support Care Cancer. 2018 Oct; 26(10):3365-3377. PMID: 29651597.
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Sawka AM, Ghai S, Tomlinson G, Rotstein L, Gilbert R, Gullane P, Pasternak J, Brown D, de Almeida J, Irish J, Chepeha D, Higgins K, Monteiro E, Jones JM, Gafni A, Goldstein DP. A protocol for a Canadian prospective observational study of decision-making on active surveillance or surgery for low-risk papillary thyroid cancer. BMJ Open. 2018 04 12; 8(4):e020298. PMID: 29654030.
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Davies JC, Chan HHL, Bernstein JM, Goldstein DP, Irish JC, Gilbert RW. Orbital Floor Reconstruction: 3-Dimensional Analysis Shows Comparable Morphology of Scapular and Iliac Crest Bone Grafts. J Oral Maxillofac Surg. 2018 09; 76(9):2011-2018. PMID: 29679587.
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Greenplate A, Wang K, Tripathi RM, Palma N, Ali SM, Stephens PJ, Miller VA, Shyr Y, Guo Y, Reddy NM, Kozhaya L, Unutmaz D, Chen X, Irish JM, Davé UP. Genomic Profiling of T-Cell Neoplasms Reveals Frequent JAK1 and JAK3 Mutations With Clonal Evasion From Targeted Therapies. JCO Precis Oncol. 2018; 2018. PMID: 30079384.
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Muhanna N, Chan H, Qiu J, Daly M, Khan T, Doglietto F, Kucharczyk W, Goldstein DP, Irish JC, de Almeida JR. Volumetric Analysis of Endoscopic and Maxillary Swing Surgical Approaches for Nasopharyngectomy. J Neurol Surg B Skull Base. 2018 Oct; 79(5):466-474. PMID: 30210974.
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Diggins KE, Gandelman JS, Roe CE, Irish JM. Generating Quantitative Cell Identity Labels with Marker Enrichment Modeling (MEM). Curr Protoc Cytom. 2018 01 18; 83:10.21.1-10.21.28. PMID: 29345329.
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Earl DC, Ferrell PB, Leelatian N, Froese JT, Reisman BJ, Irish JM, Bachmann BO. Discovery of human cell selective effector molecules using single cell multiplexed activity metabolomics. Nat Commun. 2018 01 02; 9(1):39. PMID: 29295987.
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Josefsson SE, Huse K, Kolstad A, Beiske K, Pende D, Steen CB, Inderberg EM, Lingjærde OC, Østenstad B, Smeland EB, Levy R, Irish JM, Myklebust JH. T Cells Expressing Checkpoint Receptor TIGIT Are Enriched in Follicular Lymphoma Tumors and Characterized by Reversible Suppression of T-cell Receptor Signaling. Clin Cancer Res. 2018 02 15; 24(4):870-881. PMID: 29217528.
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Muhanna N, Di Grappa MA, Chan HHL, Khan T, Jin CS, Zheng Y, Irish JC, Bratman SV. Cell-Free DNA Kinetics in a Pre-Clinical Model of Head and Neck Cancer. Sci Rep. 2017 12 01; 7(1):16723. PMID: 29196748.
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Lalani N, Huang SH, Rotstein C, Yu E, Irish J, O'Sullivan B. Skull base or cervical vertebral osteomyelitis following chemoradiotherapy for pharyngeal carcinoma: A serious but treatable complication. Clin Transl Radiat Oncol. 2018 Jan; 8:40-44. PMID: 29594240.
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Hall SF, Irish J, Groome P, Griffiths R, Hurlbut D. Do Lower-Risk Thyroid Cancer Patients Who Live in Regions with More Aggressive Treatments Have Better Outcomes? Thyroid. 2017 10; 27(10):1246-1257. PMID: 28851261.
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Hosni A, McMullen C, Huang SH, Xu W, Su J, Bayley A, Bratman SV, Cho J, Giuliani M, Kim J, Ringash J, Waldron J, Spreafico A, Weinreb I, de Almeida JR, Brown DH, Irish JC, O'Sullivan B, Goldstein DP, Hope A. Lymph node ratio relationship to regional failure and distant metastases in oral cavity cancer. Radiother Oncol. 2017 08; 124(2):225-231. PMID: 28838425.
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Czerwonka L, Bissada E, Goldstein DP, Wood RE, Lam EW, Yu E, Lazinski D, Irish JC. High-resolution cone-beam computed tomography for assessment of bone invasion in oral cancer: Comparison with conventional computed tomography. Head Neck. 2017 10; 39(10):2016-2020. PMID: 28703386.
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Tsang GFZ, Zhang H, Yao C, Kolarski M, Gullane PJ, Irish JC, Brown DH, Chepeha DB, Goldstein DP, Gilbert RW, de Almeida JR. Hardware complications in oromandibular defects: Comparing scapular and fibular based free flap reconstructions. Oral Oncol. 2017 08; 71:163-168. PMID: 28688686.
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Eskander A, Mifsud M, Irish J, Gullane P, Gilbert R, Brown D, de Almeida JR, Urbach DR, Goldstein DP. Overview of surgery for laryngeal and hypopharyngeal cancer in Ontario, 2003-2010. Head Neck. 2017 08; 39(8):1559-1567. PMID: 28593742.
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Chan MW, Yu E, Bartlett E, O'Sullivan B, Su J, Waldron J, Ringash J, Bratman SV, Chen YA, Irish J, Kim J, Gullane P, Gilbert R, Chepeha D, Perez-Ordonez B, Weinreb I, Hansen A, Tong L, Xu W, Huang SH. Morphologic and topographic radiologic features of human papillomavirus-related and -unrelated oropharyngeal carcinoma. Head Neck. 2017 08; 39(8):1524-1534. PMID: 28580605.
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Xu JJ, Yu E, McMullen C, Pasternak J, Brierley J, Tsang R, Zhang H, Eskander A, Rotstein L, Sawka AM, Gilbert R, Irish J, Gullane P, Brown D, de Almeida JR, Goldstein DP. Patterns of regional recurrence in papillary thyroid cancer patients with lateral neck metastases undergoing neck dissection. J Otolaryngol Head Neck Surg. 2017 May 31; 46(1):43. PMID: 28569186.
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Mifsud M, Eskander A, Irish J, Gullane P, Gilbert R, Brown D, de Almeida JR, Urbach DR, Goldstein DP. Evolving trends in head and neck cancer epidemiology: Ontario, Canada 1993-2010. Head Neck. 2017 09; 39(9):1770-1778. PMID: 28557276.
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Yao CM, Ziai H, Tsang G, Copeland A, Brown D, Irish JC, Gilbert RW, Goldstein DP, Gullane PJ, de Almeida JR. Surgical site infections following oral cavity cancer resection and reconstruction is a risk factor for plate exposure. J Otolaryngol Head Neck Surg. 2017 Apr 08; 46(1):30. PMID: 28390434.
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Bernstein JM, Daly MJ, Chan H, Qiu J, Goldstein D, Muhanna N, de Almeida JR, Irish JC. Accuracy and reproducibility of virtual cutting guides and 3D-navigation for osteotomies of the mandible and maxilla. PLoS One. 2017; 12(3):e0173111. PMID: 28249001.
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Nair N, Camacho-Vanegas O, Rykunov D, Dashkoff M, Camacho SC, Schumacher CA, Irish JC, Harkins TT, Freeman E, Garcia I, Pereira E, Kendall S, Belfer R, Kalir T, Sebra R, Reva B, Dottino P, Martignetti JA. Genomic Analysis of Uterine Lavage Fluid Detects Early Endometrial Cancers and Reveals a Prevalent Landscape of Driver Mutations in Women without Histopathologic Evidence of Cancer: A Prospective Cross-Sectional Study. PLoS Med. 2016 Dec; 13(12):e1002206. PMID: 28027320.
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Myklebust JH, Brody J, Kohrt HE, Kolstad A, Czerwinski DK, Wälchli S, Green MR, Trøen G, Liestøl K, Beiske K, Houot R, Delabie J, Alizadeh AA, Irish JM, Levy R. Distinct patterns of B-cell receptor signaling in non-Hodgkin lymphomas identified by single-cell profiling. Blood. 2017 02 09; 129(6):759-770. PMID: 28011673.
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Alsaffar HA, Goldstein DP, King EV, de Almeida JR, Brown DH, Gilbert RW, Gullane PJ, Espin-Garcia O, Xu W, Irish JC. Correlation between clinical and MRI assessment of depth of invasion in oral tongue squamous cell carcinoma. J Otolaryngol Head Neck Surg. 2016 Nov 22; 45(1):61. PMID: 27876067.
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Wasserman JK, Dickson BC, Perez-Ordonez B, de Almeida JR, Irish JC, Weinreb I. INI1 (SMARCB1)-Deficient Sinonasal Carcinoma: A Clinicopathologic Report of 2 Cases. Head Neck Pathol. 2017 Jun; 11(2):256-261. PMID: 27644951.
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Guest ST, Kratche ZR, Irish JC, Wilson RC, Haddad R, Gray JW, Garrett-Mayer E, Ethier SP. Functional oncogene signatures guide rationally designed combination therapies to synergistically induce breast cancer cell death. Oncotarget. 2016 Jun 14; 7(24):36138-36153. PMID: 27153554.
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Dixon BJ, Chan H, Daly MJ, Qiu J, Vescan A, Witterick IJ, Irish JC. Three-dimensional virtual navigation versus conventional image guidance: A randomized controlled trial. Laryngoscope. 2016 07; 126(7):1510-5. PMID: 27075606.
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Keca JM, Chen J, Overchuk M, Muhanna N, MacLaughlin CM, Jin CS, Foltz WD, Irish JC, Zheng G. Nanotexaphyrin: One-Pot Synthesis of a Manganese Texaphyrin-Phospholipid Nanoparticle for Magnetic Resonance Imaging. Angew Chem Int Ed Engl. 2016 05 17; 55(21):6187-91. PMID: 27071806.
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Irish J, Eskander A. The Importance and Challenges of a Specialty-Specific National Surgical Quality Improvement Program for Head and Neck Surgery. JAMA Otolaryngol Head Neck Surg. 2016 Apr; 142(4):328-9. PMID: 26892500.
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Eskander A, Irish J, Gullane P, Gilbert R, de Almeida JR, Freeman J, Giuliani M, Urbach DR, Goldstein DP. Overview of surgery for oral cavity cancer in Ontario. Head Neck. 2016 07; 38(7):1113-8. PMID: 26040567.
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Eskander A, Goldstein DP, Irish JC. Health Services Research and Regionalization of Care-From Policy to Practice: the Ontario Experience in Head and Neck Cancer. Curr Oncol Rep. 2016 Mar; 18(3):19. PMID: 26869188.
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Irish JC, Mills JN, Turner-Ivey B, Wilson RC, Guest ST, Rutkovsky A, Dombkowski A, Kappler CS, Hardiman G, Ethier SP. Amplification of WHSC1L1 regulates expression and estrogen-independent activation of ERa in SUM-44 breast cancer cells and is associated with ERa over-expression in breast cancer. Mol Oncol. 2016 06; 10(6):850-65. PMID: 27005559.
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Lebel S, Payne AY, Mah K, Irish J, Rodin G, Devins GM. Do stigma and its psychosocial impact differ between Asian-born Chinese immigrants and Western-born Caucasians with head and neck cancer? Psychol Health Med. 2016 07; 21(5):583-92. PMID: 26850943.
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Vengalil S, Giuliani ME, Huang SH, McNiven A, Song Y, Xu W, Chan B, Hope A, Cho J, Bayley A, Ringash J, Goldstein D, Razak A, Irish J, Gilbert R, Gullane P, Waldron J, Kim J, O'Sullivan B. Clinical outcomes in patients with T4 laryngeal cancer treated with primary radiotherapy versus primary laryngectomy. Head Neck. 2016 04; 38 Suppl 1:E2035-40. PMID: 26828197.
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Passador-Santos F, Grönroos M, Irish J, Gilbert R, Gullane P, Perez-Ordonez B, Mäkitie A, Leivo I. Clinicopathological characteristics and cell cycle proteins as potential prognostic factors in myoepithelial carcinoma of salivary glands. Virchows Arch. 2016 Mar; 468(3):305-12. PMID: 26710792.
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Erovic BM, Shah MD, Bruch G, Johnston M, Kim J, O'Sullivan B, Perez-Ordonez B, Weinreb I, Atenafu EG, de Almeida JR, Gullane PJ, Brown D, Gilbert RW, Irish JC, Goldstein DP. Erratum to: Outcome analysis of 215 patients with parotid gland tumors: a retrospective cohort analysis. J Otolaryngol Head Neck Surg. 2015 Dec 15; 44:55. PMID: 26671475.
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Givi B, Eskander A, Awad MI, Kong Q, Montero PH, Palmer FL, Xu W, De Almeida JR, Lee N, O'Sullivan B, Irish JC, Gilbert R, Ganly I, Patel SG, Goldstein DP, Morris LG. Impact of elective neck dissection on the outcome of oral squamous cell carcinomas arising in the maxillary alveolus and hard palate. Head Neck. 2016 04; 38 Suppl 1:E1688-94. PMID: 26614119.
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Erovic BM, Shah MD, Bruch G, Johnston M, Johnston U, Kim J, O'Sullivan B, Perez-Ordonez B, Weinreb I, Atenafu EG, de Almeida JR, Gullane PJ, Brown D, Gilbert RW, Irish JC, Goldstein DP. Outcome analysis of 215 patients with parotid gland tumors: a retrospective cohort analysis. J Otolaryngol Head Neck Surg. 2015 Oct 29; 44:43. PMID: 26515170.
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Muhanna N, Jin CS, Huynh E, Chan H, Qiu Y, Jiang W, Cui L, Burgess L, Akens MK, Chen J, Irish JC, Zheng G. Phototheranostic Porphyrin Nanoparticles Enable Visualization and Targeted Treatment of Head and Neck Cancer in Clinically Relevant Models. Theranostics. 2015; 5(12):1428-43. PMID: 26681987.
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Muhanna N, Cui L, Chan H, Burgess L, Jin CS, MacDonald TD, Huynh E, Wang F, Chen J, Irish JC, Zheng G. Multimodal Image-Guided Surgical and Photodynamic Interventions in Head and Neck Cancer: From Primary Tumor to Metastatic Drainage. Clin Cancer Res. 2016 Feb 15; 22(4):961-70. PMID: 26463705.
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Muhanna N, MacDonald TD, Chan H, Jin CS, Burgess L, Cui L, Chen J, Irish JC, Zheng G. Porphysomes: Multimodal Nanoparticle for Primary Tumor Delineation and Lymphatic Metastasis Mapping in a Head-and-Neck Cancer Rabbit Model (Adv. Healthcare Mater. 14/2015). Adv Healthc Mater. 2015 Oct; 4(14):2163. PMID: 29896901.
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Chan HH, Siewerdsen JH, Vescan A, Daly MJ, Prisman E, Irish JC. 3D Rapid Prototyping for Otolaryngology-Head and Neck Surgery: Applications in Image-Guidance, Surgical Simulation and Patient-Specific Modeling. PLoS One. 2015; 10(9):e0136370. PMID: 26331717.
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Muhanna N, MacDonald TD, Chan H, Jin CS, Burgess L, Cui L, Chen J, Irish JC, Zheng G. Multimodal Nanoparticle for Primary Tumor Delineation and Lymphatic Metastasis Mapping in a Head-and-Neck Cancer Rabbit Model. Adv Healthc Mater. 2015 Oct; 4(14):2164-2169. PMID: 26283596.
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Fung-Kee-Fung M, Kennedy EB, Biagi J, Colgan T, D'Souza D, Elit LM, Hunter A, Irish J, McLeod R, Rosen B. The optimal organization of gynecologic oncology services: a systematic review. Curr Oncol. 2015 Aug; 22(4):e282-93. PMID: 26300679.
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Noel CW, Lee DJ, Kong Q, Xu W, Simpson C, Brown D, Gilbert RW, Gullane PJ, Irish JC, Huang SH, O'Sullivan B, Goldstein DP, de Almeida JR. Comparison of Health State Utility Measures in Patients With Head and Neck Cancer. JAMA Otolaryngol Head Neck Surg. 2015 Aug; 141(8):696-703. PMID: 26204439.
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Bernardo MM, Kaplun A, Dzinic SH, Li X, Irish J, Mujagic A, Jakupovic B, Back JB, Van Buren E, Han X, Dean I, Chen YQ, Heath E, Sakr W, Sheng S. Maspin Expression in Prostate Tumor Cells Averts Stemness and Stratifies Drug Sensitivity. Cancer Res. 2015 Sep 15; 75(18):3970-9. PMID: 26208903.
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Johnston ML, Huang SH, Waldron JN, Atenafu EG, Chan K, Cummings BJ, Gilbert RW, Goldstein D, Gullane PJ, Irish JC, Perez-Ordonez B, Weinreb I, Bayley A, Cho J, Dawson LA, Hope A, Ringash J, Witterick IJ, O'Sullivan B, Kim J. Salivary duct carcinoma: Treatment, outcomes, and patterns of failure. Head Neck. 2016 04; 38 Suppl 1:E820-6. PMID: 25916947.
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Patel SN, Cohen MA, Givi B, Dixon BJ, Gilbert RW, Gullane PJ, Brown DH, Irish JC, de Almeida JR, Higgins KM, Enepekides D, Huang SH, Waldron J, O'Sullivan B, Xu W, Su S, Goldstein DP. Salvage surgery for locally recurrent oropharyngeal cancer. Head Neck. 2016 04; 38 Suppl 1:E658-64. PMID: 25867012.
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Zheng J, Muhanna N, De Souza R, Wada H, Chan H, Akens MK, Anayama T, Yasufuku K, Serra S, Irish J, Allen C, Jaffray D. A multimodal nano agent for image-guided cancer surgery. Biomaterials. 2015 Oct; 67:160-8. PMID: 26218742.
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Wang JR, Habbous S, Espin-Garcia O, Chen D, Huang SH, Simpson C, Xu W, Liu FF, Brown DH, Gilbert RW, Gullane PJ, Irish JC, Goldstein DP, Liu G. Comorbidity and performance status as independent prognostic factors in patients with head and neck squamous cell carcinoma. Head Neck. 2016 May; 38(5):736-42. PMID: 25521753.
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Karr JR, Guturu H, Chen EY, Blair SL, Irish JM, Kotecha N, Covert MW. NetworkPainter: dynamic intracellular pathway animation in Cytobank. BMC Bioinformatics. 2015 May 25; 16:172. PMID: 26003204.
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Muhanna N, Mepham A, Mohamadi RM, Chan H, Khan T, Akens M, Besant JD, Irish J, Kelley SO. Nanoparticle-based sorting of circulating tumor cells by epithelial antigen expression during disease progression in an animal model. Nanomedicine. 2015 Oct; 11(7):1613-20. PMID: 25981337.
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Fung-Kee-Fung M, Kennedy EB, Biagi J, Colgan T, D'Souza D, Elit LM, Hunter A, Irish J, McLeod R, Rosen B. An organizational guideline for gynecologic oncology services. Int J Gynecol Cancer. 2015 May; 25(4):551-8. PMID: 25756401.
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Cui L, Lin Q, Jin CS, Jiang W, Huang H, Ding L, Muhanna N, Irish JC, Wang F, Chen J, Zheng G. A PEGylation-Free Biomimetic Porphyrin Nanoplatform for Personalized Cancer Theranostics. ACS Nano. 2015; 9(4):4484-95. PMID: 25830219.
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Hall SF, Irish JC, Gregg RW, Groome PA, Rohland S. Adherence to and uptake of clinical practice guidelines: lessons learned from a clinical practice guideline on chemotherapy concomitant with radiotherapy in head-and-neck cancer. Curr Oncol. 2015 Apr; 22(2):e61-8. PMID: 25908922.
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Green MR, Kihira S, Liu CL, Nair RV, Salari R, Gentles AJ, Irish J, Stehr H, Vicente-Dueñas C, Romero-Camarero I, Sanchez-Garcia I, Plevritis SK, Arber DA, Batzoglou S, Levy R, Alizadeh AA. Mutations in early follicular lymphoma progenitors are associated with suppressed antigen presentation. Proc Natl Acad Sci U S A. 2015 Mar 10; 112(10):E1116-25. PMID: 25713363.
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Huang SH, Xu W, Waldron J, Siu L, Shen X, Tong L, Ringash J, Bayley A, Kim J, Hope A, Cho J, Giuliani M, Hansen A, Irish J, Gilbert R, Gullane P, Perez-Ordonez B, Weinreb I, Liu FF, O'Sullivan B. Refining American Joint Committee on Cancer/Union for International Cancer Control TNM stage and prognostic groups for human papillomavirus-related oropharyngeal carcinomas. J Clin Oncol. 2015 Mar 10; 33(8):836-45. PMID: 25667292.
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Sternheim A, Daly M, Qiu J, Weersink R, Chan H, Jaffray D, Irish JC, Ferguson PC, Wunder JS. Navigated pelvic osteotomy and tumor resection: a study assessing the accuracy and reproducibility of resection planes in Sawbones and cadavers. J Bone Joint Surg Am. 2015 Jan 07; 97(1):40-6. PMID: 25568393.
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Sahgal A, Chan MW, Atenafu EG, Masson-Cote L, Bahl G, Yu E, Millar BA, Chung C, Catton C, O'Sullivan B, Irish JC, Gilbert R, Zadeh G, Cusimano M, Gentili F, Laperriere NJ. Image-guided, intensity-modulated radiation therapy (IG-IMRT) for skull base chordoma and chondrosarcoma: preliminary outcomes. Neuro Oncol. 2015 Jun; 17(6):889-94. PMID: 25543126.
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Eskander A, Irish J, Freeman J, Gullane P, Gilbert R, Groome PA, Hall SF, Urbach DR, Goldstein DP. Overview of major salivary gland cancer surgery in Ontario (2003-2010). J Otolaryngol Head Neck Surg. 2014; 43:50. PMID: 25492404.
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Anayama T, Qiu J, Chan H, Nakajima T, Weersink R, Daly M, McConnell J, Waddell T, Keshavjee S, Jaffray D, Irish JC, Hirohashi K, Wada H, Orihashi K, Yasufuku K. Localization of pulmonary nodules using navigation bronchoscope and a near-infrared fluorescence thoracoscope. Ann Thorac Surg. 2015 Jan; 99(1):224-30. PMID: 25442988.
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Sepiashvili L, Waggott D, Hui A, Shi W, Su S, Ignatchenko A, Ignatchenko V, Laureano M, Huang SH, Xu W, Weinreb I, Waldron J, O'Sullivan B, Irish JC, Boutros PC, Liu FF, Kislinger T. Integrated omic analysis of oropharyngeal carcinomas reveals human papillomavirus (HPV)-dependent regulation of the activator protein 1 (AP-1) pathway. Mol Cell Proteomics. 2014 Dec; 13(12):3572-84. PMID: 25271301.
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Goldstein DP, Ringash J, Irish JC, Gilbert R, Gullane P, Brown D, Xu W, Del Bel R, Chepeha D, Davis AM. Assessment of the Disabilities of the Arm, Shoulder, and Hand (DASH) questionnaire for use in patients after neck dissection for head and neck cancer. Head Neck. 2015 Feb; 37(2):234-42. PMID: 24375871.
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Huang SH, Patel S, O'Sullivan B, Shen X, Xu W, Weinreb I, Perez-Ordonez B, Irish J, Waldron J, Gullane P, Gilbert R, Brown D, Kim J, Freeman J, de Almeida JR, Goldstein D. Longer survival in patients with human papillomavirus-related head and neck cancer after positive postradiation planned neck dissection. Head Neck. 2015 Jul; 37(7):946-52. PMID: 24633991.
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Hall SF, Irish JC, Groome PA, Urbach DR. Practice patterns in the management of patients with differentiated thyroid cancer in Ontario Canada 2000-2008. J Otolaryngol Head Neck Surg. 2014 Jul 24; 43:29. PMID: 25055715.
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Hall SF, O'Sullivan B, Irish JC, Meyer RM, Gregg R, Groome P. Impact of the addition of chemotherapy to radiotherapy for oropharyngeal cancer in 2003-2004: Population-based study from the Province of Ontario, Canada. Head Neck. 2015 Oct; 37(10):1461-9. PMID: 24844415.
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Pyne S, Lee SX, Wang K, Irish J, Tamayo P, Nazaire MD, Duong T, Ng SK, Hafler D, Levy R, Nolan GP, Mesirov J, McLachlan GJ. Joint modeling and registration of cell populations in cohorts of high-dimensional flow cytometric data. PLoS One. 2014; 9(7):e100334. PMID: 24983991.
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Weinreb I, Zhang L, Tirunagari LM, Sung YS, Chen CL, Perez-Ordonez B, Clarke BA, Skalova A, Chiosea SI, Seethala RR, Waggott D, Boutros PC, How C, Liu FF, Irish JC, Goldstein DP, Gilbert R, Ud Din N, Assaad A, Hornick JL, Thompson LD, Antonescu CR. Novel PRKD gene rearrangements and variant fusions in cribriform adenocarcinoma of salivary gland origin. Genes Chromosomes Cancer. 2014 Oct; 53(10):845-56. PMID: 24942367.
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Zhong T, Fernandes KA, Saskin R, Sutradhar R, Platt J, Beber BA, Novak CB, McCready DR, Hofer SO, Irish JC, Baxter NN. Barriers to immediate breast reconstruction in the Canadian universal health care system. J Clin Oncol. 2014 Jul 10; 32(20):2133-41. PMID: 24888814.
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Schrader S, Buzon M, Irish J. Illuminating the Nubian 'Dark Age': a bioarchaeological analysis of dental non-metric traits during the Napatan Period. Homo. 2014 Aug; 65(4):267-80. PMID: 24951408.
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McCord C, Xu J, Xu W, Qiu X, Muhanna N, Irish J, Leong I, McComb RJ, Perez-Ordonez B, Bradley G. Association of human papilloma virus with atypical and malignant oral papillary lesions. Oral Surg Oral Med Oral Pathol Oral Radiol. 2014 Jun; 117(6):722-32. PMID: 24703405.
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Cervigne NK, Machado J, Goswami RS, Sadikovic B, Bradley G, Perez-Ordonez B, Galloni NN, Gilbert R, Gullane P, Irish JC, Jurisica I, Reis PP, Kamel-Reid S. Recurrent genomic alterations in sequential progressive leukoplakia and oral cancer: drivers of oral tumorigenesis? Hum Mol Genet. 2014 May 15; 23(10):2618-28. PMID: 24403051.
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Haerle SK, Shiau C, Goldstein DP, Qiu X, Erovic BM, Ghazarian D, Xu W, Irish JC. Merkel cell carcinoma of the head and neck: potential histopathologic predictors. Laryngoscope. 2013 Dec; 123(12):3043-8. PMID: 23754774.
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Dixon BJ, Daly MJ, Chan H, Vescan A, Witterick IJ, Irish JC. Augmented real-time navigation with critical structure proximity alerts for endoscopic skull base surgery. Laryngoscope. 2014 Apr; 124(4):853-9. PMID: 24122916.
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Erovic BM, Daly MJ, Chan HH, James AL, Papsin BC, Pothier DD, Dixon B, Irish JC. Evaluation of intraoperative cone beam computed tomography and optical drill tracking in temporal bone surgery. Laryngoscope. 2013 Nov; 123(11):2823-8. PMID: 23918182.
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Srigley J, Lankshear S, Brierley J, McGowan T, Divaris D, Yurcan M, Rossi R, Yardley T, King MJ, Ross J, Irish J, McLeod R, Sawka C. Closing the quality loop: facilitating improvement in oncology practice through timely access to clinical performance indicators. J Oncol Pract. 2013 Sep; 9(5):e255-61. PMID: 23943888.
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Shinghal T, Bissada E, Chan HB, Wood RE, Atenafu EG, Brown DH, Gilbert RW, Gullane PJ, Irish JC, Waldron J, Goldstein DP. Medial mandibulotomies: is there sufficient space in the midline to allow a mandibulotomy without compromising the dentition? J Otolaryngol Head Neck Surg. 2013 May 02; 42:32. PMID: 23663661.
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Hui AB, Lin A, Xu W, Waldron L, Perez-Ordonez B, Weinreb I, Shi W, Bruce J, Huang SH, O'Sullivan B, Waldron J, Gullane P, Irish JC, Chan K, Liu FF. Potentially prognostic miRNAs in HPV-associated oropharyngeal carcinoma. Clin Cancer Res. 2013 Apr 15; 19(8):2154-62. PMID: 23459718.
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Green MR, Gentles AJ, Nair RV, Irish JM, Kihira S, Liu CL, Kela I, Hopmans ES, Myklebust JH, Ji H, Plevritis SK, Levy R, Alizadeh AA. Hierarchy in somatic mutations arising during genomic evolution and progression of follicular lymphoma. Blood. 2013 Feb 28; 121(9):1604-11. PMID: 23297126.
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Myklebust JH, Irish JM, Brody J, Czerwinski DK, Houot R, Kohrt HE, Timmerman J, Said J, Green MR, Delabie J, Kolstad A, Alizadeh AA, Levy R. High PD-1 expression and suppressed cytokine signaling distinguish T cells infiltrating follicular lymphoma tumors from peripheral T cells. Blood. 2013 Feb 21; 121(8):1367-76. PMID: 23297127.
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Erovic BM, Kim D, Cassol C, Goldstein DP, Irish JC, Asa SL, Mete O. Prognostic and predictive markers in medullary thyroid carcinoma. Endocr Pathol. 2012 Dec; 23(4):232-42. PMID: 23150029.
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Sepiashvili L, Hui A, Ignatchenko V, Shi W, Su S, Xu W, Huang SH, O'Sullivan B, Waldron J, Irish JC, Perez-Ordonez B, Liu FF, Kislinger T. Potentially novel candidate biomarkers for head and neck squamous cell carcinoma identified using an integrated cell line-based discovery strategy. Mol Cell Proteomics. 2012 Nov; 11(11):1404-15. PMID: 22918226.
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Pagedar NA, Gilbert RW, Chan H, Daly MJ, Irish JC, Siewerdsen JH. Maxillary reconstruction using the scapular tip free flap: a radiologic comparison of 3D morphology. Head Neck. 2012 Oct; 34(10):1377-82. PMID: 22287228.
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Sawka C, Ross J, Srigley J, Irish J. The crucial role of clinician engagement in system-wide quality improvement: the Cancer Care Ontario experience. Healthc Q. 2012; 15 Spec No:38-41. PMID: 24863115.
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Reis PP, Waldron L, Perez-Ordonez B, Pintilie M, Galloni NN, Xuan Y, Cervigne NK, Warner GC, Makitie AA, Simpson C, Goldstein D, Brown D, Gilbert R, Gullane P, Irish J, Jurisica I, Kamel-Reid S. A gene signature in histologically normal surgical margins is predictive of oral carcinoma recurrence. BMC Cancer. 2011 Oct 11; 11:437. PMID: 21989116.
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Li X, Kaplun A, Lonardo F, Heath E, Sarkar FH, Irish J, Sakr W, Sheng S. HDAC1 inhibition by maspin abrogates epigenetic silencing of glutathione S-transferase pi in prostate carcinoma cells. Mol Cancer Res. 2011 Jun; 9(6):733-45. PMID: 21622623.
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Reis PP, Waldron L, Goswami RS, Xu W, Xuan Y, Perez-Ordonez B, Gullane P, Irish J, Jurisica I, Kamel-Reid S. mRNA transcript quantification in archival samples using multiplexed, color-coded probes. BMC Biotechnol. 2011 May 09; 11:46. PMID: 21549012.
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Bachar G, Hod R, Goldstein DP, Irish JC, Gullane PJ, Brown D, Gilbert RW, Hadar T, Feinmesser R, Shpitzer T. Outcome of oral tongue squamous cell carcinoma in patients with and without known risk factors. Oral Oncol. 2011 Jan; 47(1):45-50. PMID: 21167767.
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Shah MD, Goldstein DP, McCluskey SA, Miles BA, Hofer SO, Hofer S, Brown DH, Irish JC, Gullane PJ, Gilbert RW. Blood transfusion prediction in patients undergoing major head and neck surgery with free-flap reconstruction. Arch Otolaryngol Head Neck Surg. 2010 Dec; 136(12):1199-204. PMID: 21173368.
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Patel RS, Goldstein DP, Guillemaud J, Bruch GA, Brown D, Gilbert RW, Gullane PJ, Higgins KM, Irish J, Enepekides DJ. Impact of positive frozen section microscopic tumor cut-through revised to negative on oral carcinoma control and survival rates. Head Neck. 2010 Nov; 32(11):1444-51. PMID: 20091833.
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Huang SH, Perez-Ordonez B, Liu FF, Waldron J, Ringash J, Irish J, Cummings B, Siu LL, Kim J, Weinreb I, Hope A, Gullane P, Brown D, Shi W, O'Sullivan B. Atypical clinical behavior of p16-confirmed HPV-related oropharyngeal squamous cell carcinoma treated with radical radiotherapy. Int J Radiat Oncol Biol Phys. 2012 Jan 01; 82(1):276-83. PMID: 20950953.
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van Driel AA, Mureau MAM, Goldstein DP, Gilbert RW, Irish JC, Gullane PJ, Neligan PC, Hofer SOP. Aesthetic and oncologic outcome after microsurgical reconstruction of complex scalp and forehead defects after malignant tumor resection: an algorithm for treatment. Plast Reconstr Surg. 2010 Aug; 126(2):460-470. PMID: 20679830.
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Kotecha N, Krutzik PO, Irish JM. Web-based analysis and publication of flow cytometry experiments. Curr Protoc Cytom. 2010 Jul; Chapter 10:Unit10.17. PMID: 20578106.
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Irish JM, Myklebust JH, Alizadeh AA, Houot R, Sharman JP, Czerwinski DK, Nolan GP, Levy R. B-cell signaling networks reveal a negative prognostic human lymphoma cell subset that emerges during tumor progression. Proc Natl Acad Sci U S A. 2010 Jul 20; 107(29):12747-54. PMID: 20543139.
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Shrime MG, Gullane PJ, Dawson L, Kim J, Gilbert RW, Irish JC, Brown DH, Goldstein DP. The impact of adjuvant radiotherapy on survival in T1-2N1 squamous cell carcinoma of the oral cavity. Arch Otolaryngol Head Neck Surg. 2010 Mar; 136(3):225-8. PMID: 20231637.
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Cervigne NK, Reis PP, Machado J, Sadikovic B, Bradley G, Galloni NN, Pintilie M, Jurisica I, Perez-Ordonez B, Gilbert R, Gullane P, Irish J, Kamel-Reid S. Identification of a microRNA signature associated with progression of leukoplakia to oral carcinoma. Hum Mol Genet. 2009 Dec 15; 18(24):4818-29. PMID: 19776030.
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Houot R, Goldstein MJ, Kohrt HE, Myklebust JH, Alizadeh AA, Lin JT, Irish JM, Torchia JA, Kolstad A, Chen L, Levy R. Therapeutic effect of CD137 immunomodulation in lymphoma and its enhancement by Treg depletion. Blood. 2009 Oct 15; 114(16):3431-8. PMID: 19641184.
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Barker E, Trimble K, Chan H, Ramsden J, Nithiananthan S, James A, Bachar G, Daly M, Irish J, Siewerdsen J. Intraoperative use of cone-beam computed tomography in a cadaveric ossified cochlea model. Otolaryngol Head Neck Surg. 2009 May; 140(5):697-702. PMID: 19393414.
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Weinreb I, Goldstein D, Irish J, Perez-Ordonez B. Expression patterns of Trk-A, Trk-B, GRP78, and p75NRT in olfactory neuroblastoma. Hum Pathol. 2009 Sep; 40(9):1330-5. PMID: 19386345.
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Hammer MM, Kotecha N, Irish JM, Nolan GP, Krutzik PO. WebFlow: a software package for high-throughput analysis of flow cytometry data. Assay Drug Dev Technol. 2009 Feb; 7(1):44-55. PMID: 19187010.
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Sachs K, Gentles AJ, Youland R, Itani S, Irish J, Nolan GP, Plevritis SK. Characterization of patient specific signaling via augmentation of Bayesian networks with disease and patient state nodes. Annu Int Conf IEEE Eng Med Biol Soc. 2009; 2009:6624-7. PMID: 19963681.
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Kotecha N, Flores NJ, Irish JM, Simonds EF, Sakai DS, Archambeault S, Diaz-Flores E, Coram M, Shannon KM, Nolan GP, Loh ML. Single-cell profiling identifies aberrant STAT5 activation in myeloid malignancies with specific clinical and biologic correlates. Cancer Cell. 2008 Oct 07; 14(4):335-43. PMID: 18835035.
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Chan Y, Siewerdsen JH, Rafferty MA, Moseley DJ, Jaffray DA, Irish JC. Cone-beam computed tomography on a mobile C-arm: novel intraoperative imaging technology for guidance of head and neck surgery. J Otolaryngol Head Neck Surg. 2008 Feb; 37(1):81-90. PMID: 18479633.
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Jeannon JP, Goldstein DP, Bachar G, Gentili F, Irish JC. Forestier disease causing dysphagia. J Otolaryngol Head Neck Surg. 2008 Feb; 37(1):E11-4. PMID: 18479619.
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Nithiananthan S, Brock KK, Irish JC, Siewerdsen JH. Deformable registration for intra-operative cone-beam CT guidance of head and neck surgery. Annu Int Conf IEEE Eng Med Biol Soc. 2008; 2008:3634-7. PMID: 19163498.
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Hamming NM, Daly MJ, Irish JC, Siewerdsen JH. Effect of fiducial configuration on target registration error in intraoperative cone-beam CT guidance of head and neck surgery. Annu Int Conf IEEE Eng Med Biol Soc. 2008; 2008:3643-8. PMID: 19163500.
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Calvo E, Malik SN, Siu LL, Baillargeon GM, Irish J, Chin SF, Santabarbara P, Kreisberg JI, Rowinsky EK, Hidalgo M. Assessment of erlotinib pharmacodynamics in tumors and skin of patients with head and neck cancer. Ann Oncol. 2007 Apr; 18(4):761-7. PMID: 17317676.
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Irish JM, Anensen N, Hovland R, Skavland J, Børresen-Dale AL, Bruserud O, Nolan GP, Gjertsen BT. Flt3 Y591 duplication and Bcl-2 overexpression are detected in acute myeloid leukemia cells with high levels of phosphorylated wild-type p53. Blood. 2007 Mar 15; 109(6):2589-96. PMID: 17105820.
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Irish JM, Czerwinski DK, Nolan GP, Levy R. Kinetics of B cell receptor signaling in human B cell subsets mapped by phosphospecific flow cytometry. J Immunol. 2006 Aug 01; 177(3):1581-9. PMID: 16849466.
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Irish JM, Czerwinski DK, Nolan GP, Levy R. Altered B-cell receptor signaling kinetics distinguish human follicular lymphoma B cells from tumor-infiltrating nonmalignant B cells. Blood. 2006 Nov 01; 108(9):3135-42. PMID: 16835385.
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Rafferty MA, Siewerdsen JH, Chan Y, Daly MJ, Moseley DJ, Jaffray DA, Irish JC. Intraoperative cone-beam CT for guidance of temporal bone surgery. Otolaryngol Head Neck Surg. 2006 May; 134(5):801-8. PMID: 16647538.
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Irish JM, Kotecha N, Nolan GP. Mapping normal and cancer cell signalling networks: towards single-cell proteomics. Nat Rev Cancer. 2006 02; 6(2):146-55. PMID: 16491074.
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Mäkitie AA, Pintor Dos Reis P, Arora S, Macmillan C, Warner GC, Sukhai M, Dardick I, Perez-Ordonez B, Wells R, Brown D, Gilbert R, Freeman J, Gullane P, Irish J, Kamel-Reid S. Molecular characterization of salivary gland malignancy using the Smgb-Tag transgenic mouse model. Lab Invest. 2005 Aug; 85(8):947-61. PMID: 15880136.
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Arellano R, Gan BS, Salpeter MJ, Yeo E, McCluskey S, Pinto R, Irish J, Ross DC, Doyle DJ, Parkin J, Brown D, Rotstein L, Witterick I, Matthews W, Yoo J, Neligan PC, Gullane P, Lampe H. A triple-blinded randomized trial comparing the hemostatic effects of large-dose 10% hydroxyethyl starch 264/0.45 versus 5% albumin during major reconstructive surgery. Anesth Analg. 2005 Jun; 100(6):1846-1853. PMID: 15920225.
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Knox JJ, Siu LL, Chen E, Dimitroulakos J, Kamel-Reid S, Moore MJ, Chin S, Irish J, LaFramboise S, Oza AM. A Phase I trial of prolonged administration of lovastatin in patients with recurrent or metastatic squamous cell carcinoma of the head and neck or of the cervix. Eur J Cancer. 2005 Mar; 41(4):523-30. PMID: 15737556.
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Mäkitie AA, Reis PP, Zhang T, Chin SF, Gullane P, Siu LL, Kamel-Reid S, Irish J. Epstein-Barr virus DNA measured in nasopharyngeal brushings in patients with nasopharyngeal carcinoma: pilot study. J Otolaryngol. 2004 Oct; 33(5):299-303. PMID: 15931814.
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Irish JM, Hovland R, Krutzik PO, Perez OD, Bruserud Ø, Gjertsen BT, Nolan GP. Single cell profiling of potentiated phospho-protein networks in cancer cells. Cell. 2004 Jul 23; 118(2):217-28. PMID: 15260991.
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Warner GC, Reis PP, Jurisica I, Sultan M, Arora S, Macmillan C, Makitie AA, Grénman R, Reid N, Sukhai M, Freeman J, Gullane P, Irish J, Kamel-Reid S. Molecular classification of oral cancer by cDNA microarrays identifies overexpressed genes correlated with nodal metastasis. Int J Cancer. 2004 Jul 20; 110(6):857-68. PMID: 15170668.
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Chan Y, Irish JC, Wood SJ, Sommer DD, Brown DH, Gullane PJ, O'Sullivan B, Lockwood GA. Smoking cessation in patients diagnosed with head and neck cancer. J Otolaryngol. 2004 Apr; 33(2):75-81. PMID: 15518093.
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Krutzik PO, Irish JM, Nolan GP, Perez OD. Analysis of protein phosphorylation and cellular signaling events by flow cytometry: techniques and clinical applications. Clin Immunol. 2004 Mar; 110(3):206-21. PMID: 15047199.
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Warner GC, Reis PP, Makitie AA, Sukhai MA, Arora S, Jurisica I, Wells RA, Gullane P, Irish J, Kamel-Reid S. Current applications of microarrays in head and neck cancer research. Laryngoscope. 2004 Feb; 114(2):241-8. PMID: 14755198.
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Mäkitie AA, MacMillan C, Ho J, Shi W, Lee A, O'Sullivan B, Payne D, Pintilie M, Cummings B, Waldron J, Warde P, Irish J, Brown D, Gilbert R, Gullane P, Liu FF, Kamel-Reid S. Loss of p16 expression has prognostic significance in human nasopharyngeal carcinoma. Clin Cancer Res. 2003 Jun; 9(6):2177-84. PMID: 12796384.
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Groome PA, Schulze K, Boysen M, Hall SF, Mackillop WJ, O'Sullivan B, Irish JC, Warde PR, Schneider KM, Mackenzie RG, Hodson DI, Hammond JA, Gulavita SP, Eapen LJ, Dixon PF, Bissett RJ. A comparison of published head and neck stage groupings in laryngeal cancer using data from two countries. J Clin Epidemiol. 2002 Jun; 55(6):533-44. PMID: 12063095.
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Khoo ML, Freeman JL, Witterick IJ, Irish JC, Rotstein LE, Gullane PJ, Asa SL. Underexpression of p27/Kip in thyroid papillary microcarcinomas with gross metastatic disease. Arch Otolaryngol Head Neck Surg. 2002 Mar; 128(3):253-7. PMID: 11886339.
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Lueg EA, Irish JC, Katz MR, Brown DH, Gullane PJ. A patient- and observer-rated analysis of the impact of lateral rhinotomy on facial aesthetics. Arch Facial Plast Surg. 2001 Oct-Dec; 3(4):241-4. PMID: 11710857.
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Wang Y, Irish J, MacMillan C, Brown D, Xuan Y, Boyington C, Gullane P, Kamel-Reid S. High frequency of microsatellite instability in young patients with head-and-neck squamous-cell carcinoma: lack of involvement of the mismatch repair genes hMLH1 AND hMSH2. Int J Cancer. 2001 Aug 01; 93(3):353-60. PMID: 11433399.
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Shpitzer T, Gullane PJ, Neligan PC, Irish JC, Freeman JE, Van den Brekel M, Gur E. The free vascularized flap and the flap plate options: comparative results of reconstruction of lateral mandibular defects. Laryngoscope. 2000 Dec; 110(12):2056-60. PMID: 11129020.
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Popat SR, Liavaag PG, Morton R, McIvor N, Irish JC, Freeman JL. Epstein Barr virus genome in nasopharyngeal carcinomas from New Zealand. Head Neck. 2000 Aug; 22(5):505-8. PMID: 10897111.
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Curran AJ, Gullane PJ, Irish J, Macmillan C, Freeman J, Kamel-Reid S. Telomerase activity is upregulated in laryngeal squamous cell carcinoma. Laryngoscope. 2000 Mar; 110(3 Pt 1):391-6. PMID: 10718425.
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Katz MR, Irish JC, Devins GM, Rodin GM, Gullane PJ. Reliability and validity of an observer-rated disfigurement scale for head and neck cancer patients. Head Neck. 2000 Mar; 22(2):132-41. PMID: 10679900.
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Tune CE, Liavaag PG, Freeman JL, van den Brekel MW, Shpitzer T, Kerrebijn JD, Payne D, Irish JC, Ng R, Cheung RK, Dosch HM. Nasopharyngeal brush biopsies and detection of nasopharyngeal cancer in a high-risk population. J Natl Cancer Inst. 1999 May 05; 91(9):796-800. PMID: 10328111.
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Kerrebijn JD, Freeman JL, Irish JC, Witterick IJ, Brown DH, Rotstein LE, Gullane PJ. Supraomohyoid neck dissection. Is it diagnostic or therapeutic? Head Neck. 1999 Jan; 21(1):39-42. PMID: 9890349.
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Curran AJ, Gullane PJ, Waldron J, Irish J, Brown D, O'Sullivan B, Cummings B. Surgical salvage after failed radiation for paranasal sinus malignancy. Laryngoscope. 1998 Nov; 108(11 Pt 1):1618-22. PMID: 9818815.
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Irish JC, Bernstein A. Oncogenes in head and neck cancer. Laryngoscope. 1993 Jan; 103(1 Pt 1):42-52. PMID: 8421418.
This graph shows the total number of publications by year, by first, middle/unknown, or last author.
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| Year | Publications |
|---|
| 1998 | 1 | | 1999 | 2 | | 2000 | 4 | | 2001 | 2 | | 2002 | 2 | | 2003 | 1 | | 2004 | 6 | | 2005 | 3 | | 2006 | 5 | | 2007 | 1 | | 2008 | 5 | | 2009 | 6 | | 2010 | 8 | | 2011 | 3 | | 2012 | 4 | | 2013 | 8 | | 2014 | 14 | | 2015 | 24 | | 2016 | 13 | | 2017 | 13 | | 2018 | 22 | | 2019 | 26 | | 2020 | 29 | | 2021 | 34 | | 2022 | 25 | | 2023 | 28 | | 2024 | 28 | | 2025 | 9 |
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