Colorado PROFILES, The Colorado Clinical and Translational Sciences Institute (CCTSI)
Keywords
Last Name
Institution

Jessica C Cardenas

TitleAssociate Professor
InstitutionUniversity of Colorado Denver - Anschutz Medical Campus
DepartmentSOM-SRG

    Collapse Research 
    Collapse research activities and funding
    R35GM146859     (CARDENAS, JESSICA)Aug 1, 2022 - May 31, 2027
    NIH
    Endothelial regulation of inflammation in trauma and hemorrhagic shock
    Role: Principal Investigator
    F32HL120549     (CARDENAS, JESSICA)Aug 1, 2014 - Jul 31, 2016
    NIH
    Role of GPIba Receptor Shedding in Platelet Dysfunction Following Trauma
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Purvis CD, Redden S, Jacobson A, Wang YW, Campbell J, Cardenas J, Van Gent JM, Cotton BA. The impact of rapid infusers on the hemostatic potential of cryoprecipitate products. Transfusion. 2026 Feb 18. PMID: 41709069.
      View in: PubMed
    2. Sanders KE, Pokharel MD, Osborn BK, Wang YW, Wade CE, Kornblith LZ, Cohen MJ, Cardenas JC. Plasma constituents promote endothelial thromboinflammatory dysfunction after hemorrhagic shock. Shock. 2026 Feb 14. PMID: 41735192.
      View in: PubMed
    3. Redden SC, Sun DJ, Wang YW, Hartwell E, Cardenas JC, Olson SD, Cotton BA. An assessment of green plasma: The in vitro hemostatic superiority of a currently discarded blood product. Transfusion. 2026 Feb 11. PMID: 41668681.
      View in: PubMed
    4. Cohen MJ, Erickson CB, Lacroix IS, Debot M, Dzieciatkowska M, Sen S, Schaid TR, Gallagher LT, Hallas WM, Thielen ON, Cralley AL, Stocker BW, Ramser BJ, Mokhtari A, Baig H, Sublette C, Iheagwam F, Caldwell-McGee A, Cole J, Nash K, Pokharel M, Cardenas JC, Banerjee A, Moore EE, Silliman CC, Hubbard A, D'Alessandro A, Hansen KC. Multiomic analyses of longitudinal plasma samples identify thromboinflammation endotypes and trajectories in patients with trauma. Sci Transl Med. 2026 Feb 11; 18(836):eadw5223. PMID: 41671342.
      View in: PubMed
    5. Takahashi K, Yamakawa K, Siletz AE, Katsura M, Holcomb JB, Cotton BA, Wade CE, Cardenas JC, Martin M, Inaba K, Matsushima K. Hyperfibrinolysis in trauma-induced coagulopathy: exploring the role of inflammatory cytokines. J Thromb Haemost. 2025 Dec 23. PMID: 41448542.
      View in: PubMed
    6. Christensen RR, Wright KE, Ives JK, Minnick CE, Chen Q, Girgis MD, Ko C, Gibbons MM, Russell TA, Huy TC, Bercz A, Smith JJ, Bailey A, Ten Broek RPG, de Wilde RL, Zindel J, Cardenas JC, Mutsaers S, Wiseman D, Meany EA, Appel EA, Foster DS, Delitto DJ, Longaker MT, Rinkevich Y, Bauer SR, Carmichael SP. A Developmental Roadmap Toward Abdominal Adhesions Prevention Technologies. Ann Surg Open. 2025 Dec; 6(4):e637. PMID: 41451177.
      View in: PubMed
    7. LaCroix IS, Dzieciatkowska M, Cendali F, Sanders K, Wade CE, Cotton BA, Cohen MJ, D'Alessandro A, Hansen K, Cardenas JC. Multiomics reveal plasma constituents associated with thrombosis among trauma patients who do not respond to enoxaparin. Blood Vessel Thromb Hemost. 2025 Nov; 2(4):100102. PMID: 41210697.
      View in: PubMed
    8. Boya MN, Cieri IF, Rodriguez Alvarez AA, Patel S, Tinlin D, Cardenas J, Dua A. The Use of Thrombin Generation as a Predictor of Thrombosis in Peripheral Artery Disease. Ann Vasc Surg. 2025 Dec; 121:81-89. PMID: 40436136.
      View in: PubMed
    9. Lu X, Tang L, Wu Y, Hilton T, Chen X, Houck K, Fulton S, Han C, Romero S, Wang Y, Kozar R, Cardenas JC, Fu X, Zhang J, Zhao Z, Dong JF. Metabolically aberrant extracellular mitochondria induce oxidative endotheliopathy in traumatic brain injury. Blood Adv. 2025 May 13; 9(9):2079-2090. PMID: 39913776.
      View in: PubMed
    10. Carmichael S, Wiseman D, Foster D, Appel E, Cardenas J, Zindel J, Maggard-Gibbons M, Ten Broek RP, De Wilde RL, Bauer S, Mutsaers S, Russell T, Huy TC, Donahue T, Koltun W, Rinkevich Y, Ko CY. Proceedings of the American College of Surgeons Surgical Adhesions Improvement Project Summit. J Am Coll Surg. 2025 May 01; 240(5):812-819. PMID: 40013692.
      View in: PubMed
    11. Baird EW, Lammers DT, Abraham PJ, Hashmi ZG, Griffin RL, Stephens SW, Cardenas JC, Richter JR, Jansen JO, Holcomb JB. Association Between Blood Type and Mortality Among Severely Injured Patients Enrolled in the Pragmatic Randomized Optimal Platelet and Plasma Ratios Trial. J Surg Res. 2025 Feb; 306:283-289. PMID: 39823999.
      View in: PubMed
    12. Takahashi K, Yamakawa K, Siletz AE, Katsura M, Holcomb JB, Wade CE, Cardenas JC, Fox EE, Schellenberg M, Martin M, Inaba K, Matsushima K. Hyperfibrinolysis: a crucial phenotypic abnormality of posttraumatic fibrinolytic dysfunction. Res Pract Thromb Haemost. 2024 Oct; 8(7):102568. PMID: 39430866.
      View in: PubMed
    13. Richter RP, Odum JD, Margaroli C, Cardenas JC, Zheng L, Tripathi K, Wang Z, Arnold K, Sanderson RD, Liu J, Richter JR. Trauma promotes heparan sulfate modifications and cleavage that disrupt homeostatic gene expression in microvascular endothelial cells. Front Cell Dev Biol. 2024; 12:1390794. PMID: 39114570.
      View in: PubMed
    14. Lubkin DT, Mueck KM, Hatton GE, Brill JB, Sandoval M, Cardenas JC, Wade CE, Cotton BA. Does an early, balanced resuscitation strategy reduce the incidence of hypofibrinogenemia in hemorrhagic shock? Trauma Surg Acute Care Open. 2024; 9(1):e001193. PMID: 38596569.
      View in: PubMed
    15. Sanders KE, Hatton GE, Mankame AR, Allen AC, Cunningham S, Van Gent JM, Fox EE, Zhang X, Wade CE, Cotton BA, Cardenas JC. Exposure to statin therapy decreases the incidence of venous thromboembolism after trauma. J Trauma Acute Care Surg. 2024 Nov 01; 97(5):690-696. PMID: 38523132.
      View in: PubMed
    16. Cereceda L, Cardenas JC, Khoury M, Silva-Pavez E, Hidalgo Y. Impact of platelet-derived mitochondria transfer in the metabolic profiling and progression of metastatic MDA-MB-231 human triple-negative breast cancer cells. Front Cell Dev Biol. 2023; 11:1324158. PMID: 38283990.
      View in: PubMed
    17. Schriner JB, Triolo F, Gill BS, Cardenas JC, Olson SD, Cox CS. Low molecular weight heparin decreases pro-coagulant activity in clinical MSC products. Cytotherapy. 2024 02; 26(2):194-200. PMID: 38127031.
      View in: PubMed
    18. Gerard J, Van Gent JM, Cardenas J, Gage C, Meyer DE, Cox C, Wade CE, Cotton BA. Hypofibrinogenemia following injury in 186 children and adolescents: identification of the phenotype, current outcomes, and potential for intervention. Trauma Surg Acute Care Open. 2023; 8(1):e001108. PMID: 38020863.
      View in: PubMed
    19. Lammers D, Scerbo M, Davidson A, Pommerening M, Tomasek J, Wade CE, Cardenas J, Jansen J, Miller CC, Holcomb JB. Addition of aspirin to venous thromboembolism chemoprophylaxis safely decreases venous thromboembolism rates in trauma patients. Trauma Surg Acute Care Open. 2023; 8(1):e001140. PMID: 37936904.
      View in: PubMed
    20. Watson C, Saaid H, Vedula V, Cardenas JC, Henke PK, Nicoud F, Xu XY, Hunt BJ, Manning KB. Venous Thromboembolism: Review of Clinical Challenges, Biology, Assessment, Treatment, and Modeling. Ann Biomed Eng. 2024 Mar; 52(3):467-486. PMID: 37914979.
      View in: PubMed
    21. Olson SA, Osborn BK, Cotton ME, Krocker JD, Koami H, White N, Cardenas JC. Fibrinogen Fragment X Mediates Endothelial Barrier Disruption via Suppression of VE-Cadherin. J Surg Res. 2024 01; 293:639-646. PMID: 37837820.
      View in: PubMed
    22. Mankame AR, Sanders KE, Cardenas JC. TIME-DEPENDENT CHANGES IN PROINFLAMMATORY MEDIATORS ARE ASSOCIATED WITH TRAUMA-RELATED VENOUS THROMBOEMBOLISM. Shock. 2023 11 01; 60(5):637-645. PMID: 37647085.
      View in: PubMed
    23. Mankame AR, Schriner JB, Skibber MA, George MJ, Cardenas JC, Cox CS, Gill BS. Design and Development of a Clot Burst Pressure Device to Investigate Resuscitation Strategies. J Surg Res. 2023 11; 291:646-652. PMID: 37549450.
      View in: PubMed
    24. Escaffre O, Szaniszlo P, Töro G, Vilas CL, Servantes BJ, Lopez E, Juelich TL, Levine CB, McLellan SLF, Cardenas JC, Freiberg AN, Módis K. Hydrogen Sulfide Ameliorates SARS-CoV-2-Associated Lung Endothelial Barrier Disruption. Biomedicines. 2023 Jun 22; 11(7). PMID: 37509430.
      View in: PubMed
    25. Cardenas JC, Dong JF, Kozar RA. Injury-induced endotheliopathy: What you need to know. J Trauma Acute Care Surg. 2023 10 01; 95(4):454-463. PMID: 37314417.
      View in: PubMed
    26. Sanders KE, Holevinski S, Zhang X, Cotton BA, Cardenas JC. Soluble endothelial protein C receptor is an independent predictor of venous thromboembolism after severe injury: Secondary analysis of a prospective cohort study. Surgery. 2023 08; 174(2):376-381. PMID: 37270299.
      View in: PubMed
    27. Vidaurre MDPH, Osborn BK, Lowak KD, McDonald MM, Wang YW, Pa V, Richter JR, Xu Y, Arnold K, Liu J, Cardenas JC. A 3-O-sulfated heparan sulfate dodecasaccharide (12-mer) suppresses thromboinflammation and attenuates early organ injury following trauma and hemorrhagic shock. Front Immunol. 2023; 14:1158457. PMID: 37122735.
      View in: PubMed
    28. Drake WP, Hsia C, Samavati L, Yu M, Cardenas J, Gianella FG, Boscardin J, Koth LL. Risk Indicators of Sarcoidosis Evolution-Unified Protocol (RISE-UP): protocol for a multi-centre, longitudinal, observational study to identify clinical features that are predictive of sarcoidosis progression. BMJ Open. 2023 04 03; 13(4):e071607. PMID: 37012011.
      View in: PubMed
    29. Magallon RE, Harmacek LD, Arger NK, Grewal P, Powers L, Werner BR, Barkes BQ, Li L, MacPhail K, Gillespie M, White EK, Collins SE, Brown T, Cardenas J, Chen ES, Maier LA, Leach SM, Hamzeh NY, Koth LL, O'Connor BP. Standardization of flow cytometry and cell sorting to enable a transcriptomic analysis in a multi-site sarcoidosis study. PLoS One. 2023; 18(3):e0281210. PMID: 36893197.
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    30. Cotton BA, Cardenas JC. Targeting Chemoprophylaxis in Venous Thromboembolism Using Biomarker Guidance-Reply. JAMA Surg. 2023 02 01; 158(2):221-222. PMID: 36416852.
      View in: PubMed
    31. Van Gent JM, Clements TW, Lubkin DT, Wade CE, Cardenas JC, Kao LS, Cotton BA. Predicting Futility in Severely Injured Patients: Using Arrival Lab Values and Physiology to Support Evidence-Based Resource Stewardship. J Am Coll Surg. 2023 04 01; 236(4):874-880. PMID: 36728085.
      View in: PubMed
    32. Faraoni EY, O'Brien BJ, Strickland LN, Osborn BK, Mota V, Chaney J, Atkins CL, Cen P, Rowe J, Cardenas J, Poulsen KL, Wray CJ, Thosani NC, Bailey-Lundberg JM. Radiofrequency Ablation Remodels the Tumor Microenvironment and Promotes Neutrophil-Mediated Abscopal Immunomodulation in Pancreatic Cancer. Cancer Immunol Res. 2023 01 03; 11(1):4-12. PMID: 36367967.
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    33. Majumdar M, Hall RP, Feldman Z, Goudot G, Sumetsky N, Jessula S, Kirshkaln A, Bellomo T, Chang D, Cardenas J, Patell R, Eagleton M, Dua A. Predicting Arterial Thrombotic Events Following Peripheral Revascularization Using Objective Viscoelastic Data. J Am Heart Assoc. 2023 01 03; 12(1):e027790. PMID: 36565191.
      View in: PubMed
    34. Chen-Goodspeed A, Dronavalli G, Zhang X, Podbielski JM, Patel B, Modis K, Cotton BA, Wade CE, Cardenas JC. Antithrombin Activity Is Associated with Persistent Thromboinflammation and Mortality in Patients with Severe COVID-19 Illness. Acta Haematol. 2023; 146(2):117-124. PMID: 36538905.
      View in: PubMed
    35. Pretorius D, Richter RP, Anand T, Cardenas JC, Richter JR. Alterations in heparan sulfate proteoglycan synthesis and sulfation and the impact on vascular endothelial function. Matrix Biol Plus. 2022 Dec; 16:100121. PMID: 36160687.
      View in: PubMed
    36. Vincent LE, Talanker MM, Butler DD, Zhang X, Podbielski JM, Wang YW, Chen-Goodspeed A, Hernandez Gonzalez SL, Fox EE, Cotton BA, Wade CE, Cardenas JC. Association of Changes in Antithrombin Activity Over Time With Responsiveness to Enoxaparin Prophylaxis and Risk of Trauma-Related Venous Thromboembolism. JAMA Surg. 2022 08 01; 157(8):713-721. PMID: 35731524.
      View in: PubMed
    37. Schriner JB, George MJ, Cardenas JC, Olson SD, Mankiewicz KA, Cox CS, Gill BS, Wade CE. PLATELET FUNCTION IN TRAUMA: IS CURRENT TECHNOLOGY IN FUNCTION TESTING MISSING THE MARK IN INJURED PATIENTS? Shock. 2022 07 01; 58(1):1-13. PMID: 35984758.
      View in: PubMed
    38. Kalkwarf KJ, Cardenas JC, Wade CE, Cotton BA. Green Plasma Has a Superior Hemostatic Profile Compared With Standard Color Plasma. Am Surg. 2022 Aug; 88(8):1970-1975. PMID: 35476552.
      View in: PubMed
    39. Richter RP, Joiner DM, Griffin RL, Jansen JO, Kerby JD, Wade CE, Holcomb JB, Cardenas JC, Richter JR. Endotheliopathy is Associated with a 24-hour Fibrinolysis Phenotype Described by Low TEG Lysis and High D-Dimer after Trauma: a Secondary Analysis of the PROPPR Study. Ann Surg Open. 2022 Mar; 3(1). PMID: 35693425.
      View in: PubMed
    40. Cardenas JC. Thrombin Generation Following Severe Trauma: Mechanisms, Modulators, and Implications for Hemostasis and Thrombosis. Shock. 2021 11 01; 56(5):682-690. PMID: 33660669.
      View in: PubMed
    41. Pati S, Fennern E, Holcomb JB, Barry M, Trivedi A, Cap AP, Martin MJ, Wade C, Kozar R, Cardenas JC, Rappold JF, Spiegel R, Schreiber MA. Treating the endotheliopathy of SARS-CoV-2 infection with plasma: Lessons learned from optimized trauma resuscitation with blood products. Transfusion. 2021 07; 61 Suppl 1:S336-S347. PMID: 34269437.
      View in: PubMed
    42. Krocker J, Cardenas JC. What's New in Shock, July 2021? Shock. 2021 07 01; 56(1):1-4. PMID: 34196626.
      View in: PubMed
    43. Rahbar E, Cotton BA, Wade CE, Cardenas JC. Acquired antithrombin deficiency is a risk factor for venous thromboembolism after major trauma. Thromb Res. 2021 08; 204:9-12. PMID: 34091120.
      View in: PubMed
    44. Holcomb JB, Sauaia A, Cardenas JC. Tranexamic Acid and Safety in the Right Patient. JAMA Surg. 2021 Apr 14; e210929. PMID: 33851968.
      View in: PubMed
    45. Clements T, McCoy C, Assen S, Cardenas J, Wade C, Meyer D, Cotton BA. The prehospital use of younger age whole blood is associated with an improved arrival coagulation profile. J Trauma Acute Care Surg. 2021 04 01; 90(4):607-614. PMID: 33405468.
      View in: PubMed
    46. Zaza M, Meyer DE, Wang YW, George M, Daniels K, Cardenas JC, Cotton BA. The Impact of Rapid Infuser Use on the Platelet Count, Platelet Function, and Hemostatic Potential of Whole Blood. J Surg Res. 2021 04; 260:76-81. PMID: 33326931.
      View in: PubMed
    47. Assen S, Cardenas J, George M, Wang YW, Wade CE, Meyer D, Cotton BA. Hemostatic potential of cold-stored non-leukoreduced whole blood over time: An assessment of platelet function and thrombin generation for optimal shelf life. J Trauma Acute Care Surg. 2020 09; 89(3):429-434. PMID: 32467473.
      View in: PubMed
    48. Lopez E, Peng Z, Kozar RA, Cao Y, Ko TC, Wade CE, Cardenas JC. Antithrombin III Contributes to the Protective Effects of Fresh Frozen Plasma Following Hemorrhagic Shock by Preventing Syndecan-1 Shedding and Endothelial Barrier Disruption. Shock. 2020 02; 53(2):156-163. PMID: 31389906.
      View in: PubMed
    49. Cardenas JC, Wang YW, Karri JV, Vincent S, Cap AP, Cotton BA, Wade CE. Supplementation with antithrombin III ex vivo optimizes enoxaparin responses in critically injured patients. Thromb Res. 2020 03; 187:131-138. PMID: 31986476.
      View in: PubMed
    50. Rowland B, Savarraj JPJ, Karri J, Zhang X, Cardenas J, Choi HA, Holcomb JB, Wade CE. Acute Inflammation in Traumatic Brain Injury and Polytrauma Patients Using Network Analysis. Shock. 2020 01; 53(1):24-34. PMID: 30939502.
      View in: PubMed
    51. Cardenas JC, Wade CE, White NJ. A Reply to "Carriage Before the Horse," a Letter to the Editor in reference to "TEG Lysis Shutdown Represents Coagulopathy in Bleeding Trauma Patients: Analysis of the PROPPR Cohort" (Shock 51(3):273-283, 2019). Shock. 2019 12; 52(6):640-641. PMID: 30889045.
      View in: PubMed
    52. Lopez E, Srivastava AK, Burchfield J, Wang YW, Cardenas JC, Togarrati PP, Miyazawa B, Gonzalez E, Holcomb JB, Pati S, Wade CE. Platelet-derived- Extracellular Vesicles Promote Hemostasis and Prevent the Development of Hemorrhagic Shock. Sci Rep. 2019 11 27; 9(1):17676. PMID: 31776369.
      View in: PubMed
    53. Myers SP, Brown JB, Leeper CM, Kutcher ME, Chen X, Wade CE, Holcomb JB, Schreiber MA, Cardenas JC, Rosengart MR, Neal MD. Early versus late venous thromboembolism: A secondary analysis of data from the PROPPR trial. Surgery. 2019 09; 166(3):416-422. PMID: 31230842.
      View in: PubMed
    54. Cardenas JC, Wade CE, Cotton BA, George MJ, Holcomb JB, Schreiber MA, White NJ. TEG Lysis Shutdown Represents Coagulopathy in Bleeding Trauma Patients: Analysis of the PROPPR Cohort. Shock. 2019 03; 51(3):273-283. PMID: 29664836.
      View in: PubMed
    55. Wade CE, Matijevic N, Wang YW, Rodriguez EG, Lopez E, Ostrowski SR, Cardenas JC, Baer LA, Chen TA, Tomasek JS, Henriksen HH, Stensballe J, Cotton BA, Holcomb JB, Johansson PI. Absences of Endothelial Microvesicle Changes in the Presence of the Endotheliopathy of Trauma. Shock. 2019 02; 51(2):180-184. PMID: 29621120.
      View in: PubMed
    56. Gonzalez Rodriguez E, Cardenas JC, Cox CS, Kitagawa RS, Stensballe J, Holcomb JB, Johansson PI, Wade CE. Traumatic brain injury is associated with increased syndecan-1 shedding in severely injured patients. Scand J Trauma Resusc Emerg Med. 2018 Nov 21; 26(1):102. PMID: 30463625.
      View in: PubMed
    57. Cardenas JC, Zhang X, Fox EE, Cotton BA, Hess JR, Schreiber MA, Wade CE, Holcomb JB. Platelet transfusions improve hemostasis and survival in a substudy of the prospective, randomized PROPPR trial. Blood Adv. 2018 07 24; 2(14):1696-1704. PMID: 30030268.
      View in: PubMed
    58. Gonzalez Rodriguez E, Cardenas JC, Lopez E, Cotton BA, Tomasek JS, Ostrowski SR, Baer LA, Stensballe J, Holcomb JB, Johansson PI, Wade CE. Early Identification of the Patient with Endotheliopathy of Trauma by Arrival Serum Albumin. Shock. 2018 07; 50(1):31-37. PMID: 29049135.
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    59. Blackburn SL, Kumar PT, McBride D, Zeineddine HA, Leclerc J, Choi HA, Dash PK, Grotta J, Aronowski J, Cardenas JC, Doré S. Unique Contribution of Haptoglobin and Haptoglobin Genotype in Aneurysmal Subarachnoid Hemorrhage. Front Physiol. 2018; 9:592. PMID: 29904350.
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    60. Karri J, Cardenas JC, Matijevic N, Wang YW, Choi S, Zhu L, Cotton BA, Kitagawa R, Holcomb JB, Wade CE. Early Fibrinolysis Associated with Hemorrhagic Progression Following Traumatic Brain Injury. Shock. 2017 12; 48(6):644-650. PMID: 28614144.
      View in: PubMed
    61. Wade CE, Cardenas JC, Cap AP. Reply to: is "Thrombin Burst" Now the Worst Option in Trauma? Shock. 2017 06; 47(6):781-782. PMID: 27918370.
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    62. Rodriguez EG, Ostrowski SR, Cardenas JC, Baer LA, Tomasek JS, Henriksen HH, Stensballe J, Cotton BA, Holcomb JB, Johansson PI, Wade CE. Syndecan-1: A Quantitative Marker for the Endotheliopathy of Trauma. J Am Coll Surg. 2017 Sep; 225(3):419-427. PMID: 28579548.
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    63. Cardenas JC, Holcomb JB. Time to plasma transfusion: a patient centered approach and modifiable risk factor. Transfusion. 2017 04; 57(4):869-873. PMID: 28394421.
      View in: PubMed
    64. Johansson PI, Henriksen HH, Stensballe J, Gybel-Brask M, Cardenas JC, Baer LA, Cotton BA, Holcomb JB, Wade CE, Ostrowski SR. Traumatic Endotheliopathy: A Prospective Observational Study of 424 Severely Injured Patients. Ann Surg. 2017 03; 265(3):597-603. PMID: 27144442.
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    65. Henriksen HH, Grand AG, Viggers S, Baer LA, Solbeck S, Cotton BA, Matijevic N, Ostrowski SR, Stensballe J, Fox EE, Chen TA, Holcomb JB, Johansson PI, Cardenas JC, Wade CE. Impact of blood products on platelet function in patients with traumatic injuries: a translational study. J Surg Res. 2017 06 15; 214:154-161. PMID: 28624038.
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    66. Ostrowski SR, Henriksen HH, Stensballe J, Gybel-Brask M, Cardenas JC, Baer LA, Cotton BA, Holcomb JB, Wade CE, Johansson PI. Sympathoadrenal activation and endotheliopathy are drivers of hypocoagulability and hyperfibrinolysis in trauma: A prospective observational study of 404 severely injured patients. J Trauma Acute Care Surg. 2017 02; 82(2):293-301. PMID: 27779595.
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    67. Wade CE, Baer LA, Cardenas JC, Folkerson LE, Nutall-Aurora K, Cotton BA, Matijevic N, Holcomb JB, Cross JM, Huzar T. Upon admission coagulation and platelet function in patients with thermal and electrical injuries. Burns. 2016 Dec; 42(8):1704-1711. PMID: 27692780.
      View in: PubMed
    68. Chang R, Cardenas JC, Wade CE, Holcomb JB. Advances in the understanding of trauma-induced coagulopathy. Blood. 2016 08 25; 128(8):1043-9. PMID: 27381903.
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    69. White NJ, Wang Y, Fu X, Cardenas JC, Martin EJ, Brophy DF, Wade CE, Wang X, St John AE, Lim EB, Stern SA, Ward KR, López JA, Chung D. Post-translational oxidative modification of fibrinogen is associated with coagulopathy after traumatic injury. Free Radic Biol Med. 2016 07; 96:181-9. PMID: 27105953.
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    70. Cardenas JC, Cap AP, Swartz MD, Huby Mdel P, Baer LA, Matijevic N, Cotton BA, Holcomb JB, Wade CE. PLASMA RESUSCITATION PROMOTES COAGULATION HOMEOSTASIS FOLLOWING SHOCK-INDUCED HYPERCOAGULABILITY. Shock. 2016 Feb; 45(2):166-73. PMID: 26529664.
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    71. Matijevic N, Wang YW, Holcomb JB, Kozar R, Cardenas JC, Wade CE. Microvesicle phenotypes are associated with transfusion requirements and mortality in subjects with severe injuries. J Extracell Vesicles. 2015; 4:29338. PMID: 26689982.
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    72. Rahbar E, Cardenas JC, Matijevic N, Del Junco D, Podbielski J, Cohen MJ, Cotton BA, Holcomb JB, Wade CE. Trauma, Time, and Transfusions: A Longitudinal Analysis of Coagulation Markers in Severely Injured Trauma Patients Receiving Modified Whole Blood or Component Blood Products. Shock. 2015 Nov; 44(5):417-25. PMID: 26263433.
      View in: PubMed
    73. Pommerening MJ, Cardenas JC, Radwan ZA, Wade CE, Holcomb JB, Cotton BA. Hypercoagulability after energy drink consumption. J Surg Res. 2015 Dec; 199(2):635-40. PMID: 26188956.
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    74. Liras IN, Cotton BA, Cardenas JC, Harting MT. Prevalence and impact of admission hyperfibrinolysis in severely injured pediatric trauma patients. Surgery. 2015 Sep; 158(3):812-8. PMID: 26070849.
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    75. Rahbar E, Cardenas JC, Baimukanova G, Usadi B, Bruhn R, Pati S, Ostrowski SR, Johansson PI, Holcomb JB, Wade CE. Endothelial glycocalyx shedding and vascular permeability in severely injured trauma patients. J Transl Med. 2015 Apr 12; 13:117. PMID: 25889764.
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    76. Wade CE, Cardenas JC. Obesity and the balancing act of endothelial damage and repair: Commentary on an article by Maria-Victoria Noci, MD, et al.: "Changes in endothelial microparticles and endothelial progenitor cells in obese patients in response to surgical stress". J Bone Joint Surg Am. 2015 Mar 04; 97(5):e28. PMID: 25740037.
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    77. Cardenas JC, Rahbar E, Pommerening MJ, Baer LA, Matijevic N, Cotton BA, Holcomb JB, Wade CE. Measuring thrombin generation as a tool for predicting hemostatic potential and transfusion requirements following trauma. J Trauma Acute Care Surg. 2014 Dec; 77(6):839-45. PMID: 25099452.
      View in: PubMed
    78. Pommerening MJ, Goodman MD, Farley DL, Cardenas JC, Podbielski J, Matijevic N, Wade CE, Holcomb JB, Cotton BA. Early diagnosis of clinically significant hyperfibrinolysis using thrombelastography velocity curves. J Am Coll Surg. 2014 Dec; 219(6):1157-66. PMID: 25458237.
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    79. Cardenas JC, Wade CE, Holcomb JB. Mechanisms of trauma-induced coagulopathy. Curr Opin Hematol. 2014 Sep; 21(5):404-9. PMID: 25010798.
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    80. Sarkissyan S, Sarkissyan M, Wu Y, Cardenas J, Koeffler HP, Vadgama JV. IGF-1 regulates Cyr61 induced breast cancer cell proliferation and invasion. PLoS One. 2014; 9(7):e103534. PMID: 25062088.
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    81. Matijevic N, Wang YW, Wade CE, Holcomb JB, Cotton BA, Schreiber MA, Muskat P, Fox EE, Del Junco DJ, Cardenas JC, Rahbar MH, Cohen MJ. Cellular microparticle and thrombogram phenotypes in the Prospective Observational Multicenter Major Trauma Transfusion (PROMMTT) study: correlation with coagulopathy. Thromb Res. 2014 Sep; 134(3):652-8. PMID: 25086657.
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    82. Huby Mdel P, Cardenas JC, Baer LA, Pawelczyk NS, Salsbury JR, Wang YW, Matijevic N, Holcomb JB, Wade CE. Establishment of methods for performing thrombelastography and calibrated automated thrombography in rats. Shock. 2014 Jul; 42(1):27-30. PMID: 24667614.
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    83. Cardenas JC, Matijevic N, Baer LA, Holcomb JB, Cotton BA, Wade CE. Elevated tissue plasminogen activator and reduced plasminogen activator inhibitor promote hyperfibrinolysis in trauma patients. Shock. 2014 Jun; 41(6):514-21. PMID: 24667610.
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    84. Karri JV, Cardenas JC, Johansson PI, Matijevic N, Cotton BA, Wade CE, Holcomb JB. In vitro efficacy of RiaSTAP after rapid reconstitution. J Surg Res. 2014 Aug; 190(2):655-61. PMID: 24602482.
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