Colorado PROFILES, The Colorado Clinical and Translational Sciences Institute (CCTSI)
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Last Name
Institution

Andrew Christopher Leroux

TitleAssistant Professor
InstitutionUniversity of Colorado Denver - Anschutz Medical Campus
DepartmentCSPH-Bio Info General Ops

    Collapse Bibliographic 
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Carpenter JS, Crouse JJ, Park SH, Shin M, Tonini E, Guo W, Merikangas KR, Iorfino F, Leroux A, Nichles A, Zmicerevska N, Scott J, Scott EM, Hickie IB. Actigraphy-derived circadian rhythms, sleep-wake patterns, and physical activity across clinical stages and pathophysiological subgroups in young people presenting for mental health care. J Psychiatr Res. 2025 Jun; 186:396-406. PMID: 40311436.
      View in: PubMed
    2. Kang SJ, Guo W, Zipunnikov V, Glaus J, Lamers F, Strippoli MF, Marques-Vidal P, Vaucher J, de La Harpe R, Vollenweider P, Preisig M, Merikangas KR, Leroux A. Impact of cardiovascular risk factors on associations between state and trait indices of major depression disorder and objectively assessed physical activity, sleep and circadian rhythmicity within a population based cohort. J Affect Disord. 2025 Jun 01; 378:360-372. PMID: 39993533.
      View in: PubMed
    3. Wanigatunga AA, Dong Y, Jin M, Leroux A, Cui E, Zhou X, Zhao A, Schrack JA, Bandeen-Roche K, Walston JD, Xue QL, Lindquist MA, Crainiceanu CM. Moderate-to-Vigorous Physical Activity at any Dose Reduces All-Cause Dementia Risk Regardless of Frailty Status. J Am Med Dir Assoc. 2025 Mar; 26(3):105456. PMID: 39826907.
      View in: PubMed
    4. Zhao A, Cui E, Leroux A, Zhou X, Muschelli J, Lindquist MA, Crainiceanu CM. Objectively Measured Physical Activity Using Wrist-Worn Accelerometers as a Predictor of Incident Alzheimer's Disease in the UK Biobank. J Gerontol A Biol Sci Med Sci. 2025 Jan 16; 80(2). PMID: 39656932.
      View in: PubMed
    5. Agarwala N, Zipunnikov V, Crainiceanu C, Leroux A. Quantifying the time-varying association between objectively measured physical activity and mortality in US older adults over a 12-year follow-up period: the NHANES 2003-2006 study. BMJ Evid Based Med. 2024 Nov 22; 29(6):409-414. PMID: 38471753.
      View in: PubMed
    6. Wrobel J, Soupir AC, Hayes MT, Peres LC, Vu T, Leroux A, Fridley BL. mxfda: a comprehensive toolkit for functional data analysis of single-cell spatial data. Bioinform Adv. 2024; 4(1):vbae155. PMID: 39552929.
      View in: PubMed
    7. Kang SJ, Leroux A, Guo W, Dey D, Strippoli MF, Di J, Vaucher J, Marques-Vidal P, Vollenweider P, Preisig M, Merikangas KR, Zipunnikov V. Integrative Modeling of Accelerometry-Derived Sleep, Physical Activity, and Circadian Rhythm Domains With Current or Remitted Major Depression. JAMA Psychiatry. 2024 Sep 01; 81(9):911-918. PMID: 38865117.
      View in: PubMed
    8. Smirnova E, Cui E, Tabacu L, Leroux A. Scalar-on-function regression: Estimation and inference under complex survey designs. Stat Med. 2024 Oct 15; 43(23):4559-4574. PMID: 39136337.
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    9. Koffman L, Crainiceanu C, Leroux A. Walking fingerprinting. J R Stat Soc Ser C Appl Stat. 2024 Nov; 73(5):1221-1241. PMID: 39552748.
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    10. Goldberg E, Bounds M, Serina P, Gomez Picazo J, Lo D, Roberts S, Dandapani H, Keene S, Thomas K, Leroux A. Commercial entities own the online narrative on home care: Impacts on quality, content, and readability. J Am Geriatr Soc. 2024 Oct; 72(10):3253-3256. PMID: 38958105.
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    11. Leroux A, Cui E, Smirnova E, Muschelli J, Schrack JA, Crainiceanu CM. NHANES 2011-2014: Objective Physical Activity Is the Strongest Predictor of All-Cause Mortality. Med Sci Sports Exerc. 2024 Oct 01; 56(10):1926-1934. PMID: 38949152.
      View in: PubMed
    12. Leroux A, Crainiceanu C, Zeger S, Taub M, Ansari B, Wager TD, Bayman E, Coffey C, Langefeld C, McCarthy R, Tsodikov A, Brummet C, Clauw DJ, Edwards RR, Lindquist MA. Statistical modeling of acute and chronic pain patient-reported outcomes obtained from ecological momentary assessment. Pain. 2024 Sep 01; 165(9):1955-1965. PMID: 38718196.
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    13. Godbole S, Leroux A, Brooks-Russell A, Subramanian PS, Kosnett MJ, Wrobel J. A Study of Pupil Response to Light as a Digital Biomarker of Recent Cannabis Use. Digit Biomark. 2024 Jan-Dec; 8(1):83-92. PMID: 38682092.
      View in: PubMed
    14. Lateef TM, Dey D, Leroux A, Cui L, Xiao M, Zipunnikov V, Merikangas KR. Association Between Electronic Diary-Rated Sleep, Mood, Energy, and Stress With Incident Headache in a Community-Based Sample. Neurology. 2024 Feb 27; 102(4):e208102. PMID: 38266217.
      View in: PubMed
    15. Huang W, Hao L, Wu X, Yu X, Cui E, Leroux A. Gender difference in "second-shift" physical activity: New insights from analyzing accelerometry data in a nationally representative sample. SSM Popul Health. 2023 Dec; 24:101536. PMID: 37927817.
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    16. Zhao A, Cui E, Leroux A, Lindquist MA, Crainiceanu CM. Evaluating the prediction performance of objective physical activity measures for incident Parkinson's disease in the UK Biobank. J Neurol. 2023 Dec; 270(12):5913-5923. PMID: 37612539.
      View in: PubMed
    17. Stapp EK, Zipunnikov V, Leroux A, Cui L, Husky MM, Dey D, Merikangas KR. Specificity of affective dynamics of bipolar and major depressive disorder. Brain Behav. 2023 09; 13(9):e3134. PMID: 37574463.
      View in: PubMed
    18. Meng Q, Cui E, Leroux A, Mowry EM, Lindquist MA, Crainiceanu CM. Quantifying the Association between Objectively Measured Physical Activity and Multiple Sclerosis in the UK Biobank. Med Sci Sports Exerc. 2023 Dec 01; 55(12):2194-2202. PMID: 37535318.
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    19. Glaus J, Kang SJ, Guo W, Lamers F, Strippoli MF, Leroux A, Dey D, Plessen KJ, Vaucher J, Vollenweider P, Zipunnikov V, Merikangas KR, Preisig M. Objectively assessed sleep and physical activity in depression subtypes and its mediating role in their association with cardiovascular risk factors. J Psychiatr Res. 2023 07; 163:325-336. PMID: 37253320.
      View in: PubMed
    20. Sergazinov R, Leroux A, Cui E, Crainiceanu C, Aurora RN, Punjabi NM, Gaynanova I. A case study of glucose levels during sleep using multilevel fast function on scalar regression inference. Biometrics. 2023 12; 79(4):3873-3882. PMID: 37189239.
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    21. Koffman L, Zhang Y, Harezlak J, Crainiceanu C, Leroux A. Fingerprinting walking using wrist-worn accelerometers. Gait Posture. 2023 06; 103:92-98. PMID: 37150053.
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    22. Ledbetter MK, Tabacu L, Leroux A, Crainiceanu CM, Smirnova E. Cardiovascular mortality risk prediction using objectively measured physical activity phenotypes in NHANES 2003-2006. Prev Med. 2022 11; 164:107303. PMID: 36244522.
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    23. Karas M, Muschelli J, Leroux A, Urbanek JK, Wanigatunga AA, Bai J, Crainiceanu CM, Schrack JA. Comparison of Accelerometry-Based Measures of Physical Activity: Retrospective Observational Data Analysis Study. JMIR Mhealth Uhealth. 2022 07 22; 10(7):e38077. PMID: 35867392.
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    24. Li R, Xiao L, Smirnova E, Cui E, Leroux A, Crainiceanu CM. Fixed-effects inference and tests of correlation for?longitudinal functional data. Stat Med. 2022 07 30; 41(17):3349-3364. PMID: 35491388.
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    25. Qi G, Dutta D, Leroux A, Ray D, Muschelli J, Crainiceanu C, Chatterjee N. Genome-wide association studies of 27 accelerometry-derived physical activity measurements identified novel loci and genetic mechanisms. Genet Epidemiol. 2022 03; 46(2):122-138. PMID: 35043453.
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    26. Leroux A, Frey KP, Crainiceanu CM, Obremskey WT, Stinner DJ, Bosse MJ, Karunakar MA, O'Toole RV, Carroll EA, Hak DJ, Hayda R, Alkhoury D, Schmidt AH. Defining Incidence of Acute Compartment Syndrome in the Research Setting: A Proposed Method From the PACS Study. J Orthop Trauma. 2022 Jan 01; 36(Suppl 1):S26-S32. PMID: 34924516.
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    27. Yu X, Hao L, Crainiceanu C, Leroux A. Occupational determinants of physical activity at work: Evidence from wearable accelerometer in 2005-2006 NHANES. SSM Popul Health. 2022 Mar; 17:100989. PMID: 34977325.
      View in: PubMed
    28. Cui E, Leroux A, Smirnova E, Crainiceanu CM. Fast Univariate Inference for Longitudinal Functional Models. J Comput Graph Stat. 2022; 31(1):219-230. PMID: 35712524.
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    29. Leroux A, Xu S, Kundu P, Muschelli J, Smirnova E, Chatterjee N, Crainiceanu C. Quantifying the Predictive Performance of Objectively Measured Physical Activity on Mortality in the UK Biobank. J Gerontol A Biol Sci Med Sci. 2021 07 13; 76(8):1486-1494. PMID: 33000171.
      View in: PubMed
    30. Leroux A, Rzasa-Lynn R, Crainiceanu C, Sharma T. Wearable Devices: Current Status and Opportunities in Pain Assessment and Management. Digit Biomark. 2021 Jan-Apr; 5(1):89-102. PMID: 34056519.
      View in: PubMed
    31. Wrobel J, Muschelli J, Leroux A. Diurnal Physical Activity Patterns across Ages in a Large UK Based Cohort: The UK Biobank Study. Sensors (Basel). 2021 Feb 23; 21(4). PMID: 33672201.
      View in: PubMed
    32. Cui E, Crainiceanu CM, Leroux A. Additive Functional Cox Model. J Comput Graph Stat. 2021; 30(3):780-793. PMID: 34898969.
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    33. Tabacu L, Ledbetter M, Leroux A, Crainiceanu C, Smirnova E. Quantifying the Varying Predictive Value of Physical Activity Measures Obtained from Wearable Accelerometers on All-Cause Mortality over Short to Medium Time Horizons in NHANES 2003-2006. Sensors (Basel). 2020 Dec 22; 21(1). PMID: 33374911.
      View in: PubMed
    34. Smirnova E, Leroux A, Cao Q, Tabacu L, Zipunnikov V, Crainiceanu C, Urbanek JK. The Predictive Performance of Objective Measures of Physical Activity Derived From Accelerometry Data for 5-Year All-Cause Mortality in Older Adults: National Health and Nutritional Examination Survey 2003-2006. J Gerontol A Biol Sci Med Sci. 2020 09 16; 75(9):1779-1785. PMID: 31504213.
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    35. Wang C, Colantuoni E, Leroux A, Scharfstein DO. idem: An R Package for Inferences in Clinical Trials with Death and Missingness. J Stat Softw. 2020 May; 93. PMID: 33273895.
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    36. Di J, Spira A, Bai J, Urbanek J, Leroux A, Wu M, Resnick S, Simonsick E, Ferrucci L, Schrack J, Zipunnikov V. Joint and Individual Representation of Domains of Physical Activity, Sleep, and Circadian Rhythmicity. Stat Biosci. 2019 Jul; 11(2):371-402. PMID: 32440309.
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    37. Kudchadkar SR, Aljohani O, Johns J, Leroux A, Alsafi E, Jastaniah E, Gottschalk A, Shata NJ, Al-Harbi A, Gergen D, Nadkarni A, Crainiceanu C. Day-Night Activity in Hospitalized Children after Major Surgery: An Analysis of 2271 Hospital Days. J Pediatr. 2019 06; 209:190-197.e1. PMID: 30885646.
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    38. Leroux A, Di J, Smirnova E, Mcguffey EJ, Cao Q, Bayatmokhtari E, Tabacu L, Zipunnikov V, Urbanek JK, Crainiceanu C. Organizing and analyzing the activity data in NHANES. Stat Biosci. 2019 Jul; 11(2):262-287. PMID: 32047572.
      View in: PubMed
    39. Schrack JA, Leroux A, Fleg JL, Zipunnikov V, Simonsick EM, Studenski SA, Crainiceanu C, Ferrucci L. Using Heart Rate and Accelerometry to Define Quantity and Intensity of Physical Activity in Older Adults. J Gerontol A Biol Sci Med Sci. 2018 04 17; 73(5):668-675. PMID: 29509832.
      View in: PubMed
    40. Grigsby MR, Di J, Leroux A, Zipunnikov V, Xiao L, Crainiceanu C, Checkley W. Novel metrics for growth model selection. Emerg Themes Epidemiol. 2018; 15:4. PMID: 29483933.
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    41. Urbanek JK, Spira AP, Di J, Leroux A, Crainiceanu C, Zipunnikov V. Epidemiology of objectively measured bedtime and chronotype in US adolescents and adults: NHANES 2003-2006. Chronobiol Int. 2018 03; 35(3):416-434. PMID: 29283283.
      View in: PubMed
    42. Leroux A, Xiao L, Crainiceanu C, Checkley W. Dynamic prediction in functional concurrent regression with an application to child growth. Stat Med. 2018 04 15; 37(8):1376-1388. PMID: 29230836.
      View in: PubMed
    43. Varma VR, Dey D, Leroux A, Di J, Urbanek J, Xiao L, Zipunnikov V. Total volume of physical activity: TAC, TLAC or TAC(?). Prev Med. 2018 01; 106:233-235. PMID: 29080825.
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    44. Varma VR, Dey D, Leroux A, Di J, Urbanek J, Xiao L, Zipunnikov V. Re-evaluating the effect of age on physical activity over the lifespan. Prev Med. 2017 Aug; 101:102-108. PMID: 28579498.
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