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Gregg Tyler Beckham

TitleProfessor Adjoint
InstitutionUniversity of Colorado Boulder
DepartmentChemical & Biological Engin

    Collapse Bibliographic 
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Pardo I, Jha RK, Bermel RE, Bratti F, Gaddis M, McIntyre E, Michener W, Neidle EL, Dale T, Beckham GT, Johnson CW. Gene amplification, laboratory evolution, and biosensor screening reveal MucK as a terephthalic acid transporter in Acinetobacter baylyi ADP1. Metab Eng. 2020 Oct 01; 62:260-274. PMID: 32979486.
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    2. Fetherolf MM, Levy-Booth DJ, Navas LE, Liu J, Grigg JC, Wilson A, Katahira R, Beckham GT, Mohn WW, Eltis LD. Characterization of alkylguaiacol-degrading cytochromes P450 for the biocatalytic valorization of lignin. Proc Natl Acad Sci U S A. 2020 Sep 28. PMID: 32989155.
      View in: PubMed
    3. Knott BC, Erickson E, Allen MD, Gado JE, Graham R, Kearns FL, Pardo I, Topuzlu E, Anderson JJ, Austin HP, Dominick G, Johnson CW, Rorrer NA, Szostkiewicz CJ, Copié V, Payne CM, Woodcock HL, Donohoe BS, Beckham GT, McGeehan JE. Characterization and engineering of a two-enzyme system for plastics depolymerization. Proc Natl Acad Sci U S A. 2020 Sep 28. PMID: 32989159.
      View in: PubMed
    4. Mohamed ET, Werner AZ, Salvachúa D, Singer CA, Szostkiewicz K, Rafael Jiménez-Díaz M, Eng T, Radi MS, Simmons BA, Mukhopadhyay A, Herrgård MJ, Singer SW, Beckham GT, Feist AM. Adaptive laboratory evolution of Pseudomonas putida KT2440 improves p-coumaric and ferulic acid catabolism and tolerance. Metab Eng Commun. 2020 Dec; 11:e00143. PMID: 32963959.
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    5. Elmore JR, Dexter GN, Salvachúa D, O'Brien M, Klingeman DM, Gorday K, Michener JK, Peterson DJ, Beckham GT, Guss AM. Engineered Pseudomonas putida simultaneously catabolizes five major components of corn stover lignocellulose: Glucose, xylose, arabinose, p-coumaric acid, and acetic acid. Metab Eng. 2020 Aug 20; 62:62-71. PMID: 32828991.
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    6. Gado JE, Beckham GT, Payne CM. Improving Enzyme Optimum Temperature Prediction with Resampling Strategies and Ensemble Learning. J Chem Inf Model. 2020 Aug 24; 60(8):4098-4107. PMID: 32639729.
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    7. Bharadwaj VS, Knott BC, Ståhlberg J, Beckham GT, Crowley MF. Reply to Cosgrove: Non-enzymatic action of expansins. J Biol Chem. 2020 May 08; 295(19):6783. PMID: 32385097.
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    8. Salvachúa D, Rydzak T, Auwae R, De Capite A, Black BA, Bouvier JT, Cleveland NS, Elmore JR, Furches A, Huenemann JD, Katahira R, Michener WE, Peterson DJ, Rohrer H, Vardon DR, Beckham GT, Guss AM. Metabolic engineering of Pseudomonas putida for increased polyhydroxyalkanoate production from lignin. Microb Biotechnol. 2020 May; 13(3):813. PMID: 32237217.
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    9. Salvachúa D, Werner AZ, Pardo I, Michalska M, Black BA, Donohoe BS, Haugen SJ, Katahira R, Notonier S, Ramirez KJ, Amore A, Purvine SO, Zink EM, Abraham PE, Giannone RJ, Poudel S, Laible PD, Hettich RL, Beckham GT. Outer membrane vesicles catabolize lignin-derived aromatic compounds in Pseudomonas putida KT2440. Proc Natl Acad Sci U S A. 2020 04 28; 117(17):9302-9310. PMID: 32245809.
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    10. Thornburg NE, Pecha MB, Brandner DG, Reed ML, Vermaas JV, Michener WE, Katahira R, Vinzant TB, Foust TD, Donohoe BS, Román-Leshkov Y, Ciesielski PN, Beckham GT. Mesoscale Reaction-Diffusion Phenomena Governing Lignin-First Biomass Fractionation. ChemSusChem. 2020 Apr 03. PMID: 32246557.
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    11. Bharadwaj VS, Knott BC, Ståhlberg J, Beckham GT, Crowley MF. The hydrolysis mechanism of a GH45 cellulase and its potential relation to lytic transglycosylase and expansin function. J Biol Chem. 2020 Apr 03; 295(14):4477-4487. PMID: 32054684.
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    12. Bentley GJ, Narayanan N, Jha RK, Salvachúa D, Elmore JR, Peabody GL, Black BA, Ramirez K, De Capite A, Michener WE, Werner AZ, Klingeman DM, Schindel HS, Nelson R, Foust L, Guss AM, Dale T, Johnson CW, Beckham GT. Engineering glucose metabolism for enhanced muconic acid production in Pseudomonas putida KT2440. Metab Eng. 2020 05; 59:64-75. PMID: 31931111.
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    13. Bissaro B, Streit B, Isaksen I, Eijsink VGH, Beckham GT, DuBois JL, Røhr ÅK. Molecular mechanism of the chitinolytic peroxygenase reaction. Proc Natl Acad Sci U S A. 2020 01 21; 117(3):1504-1513. PMID: 31907317.
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    14. Hannon JR, Lynd LR, Andrade O, Benavides PT, Beckham GT, Biddy MJ, Brown N, Chagas MF, Davison BH, Foust T, Junqueira TL, Laser MS, Li Z, Richard T, Tao L, Tuskan GA, Wang M, Woods J, Wyman CE. Technoeconomic and life-cycle analysis of single-step catalytic conversion of wet ethanol into fungible fuel blendstocks. Proc Natl Acad Sci U S A. 2020 06 09; 117(23):12576-12583. PMID: 31767762.
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    15. Prates ET, Crowley MF, Skaf MS, Beckham GT. Catalytic Mechanism of Aryl-Ether Bond Cleavage in Lignin by LigF and LigG. J Phys Chem B. 2019 12 05; 123(48):10142-10151. PMID: 31687816.
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    16. Vermaas JV, Kont R, Beckham GT, Crowley MF, Gudmundsson M, Sandgren M, Ståhlberg J, Väljamäe P, Knott BC. The dissociation mechanism of processive cellulases. Proc Natl Acad Sci U S A. 2019 11 12; 116(46):23061-23067. PMID: 31666327.
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    17. Vermaas JV, Dixon RA, Chen F, Mansfield SD, Boerjan W, Ralph J, Crowley MF, Beckham GT. Passive membrane transport of lignin-related compounds. Proc Natl Acad Sci U S A. 2019 11 12; 116(46):23117-23123. PMID: 31659054.
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    18. Salvachúa D, Rydzak T, Auwae R, De Capite A, Black BA, Bouvier JT, Cleveland NS, Elmore JR, Huenemann JD, Katahira R, Michener WE, Peterson DJ, Rohrer H, Vardon DR, Beckham GT, Guss AM. Metabolic engineering of Pseudomonas putida for increased polyhydroxyalkanoate production from lignin. Microb Biotechnol. 2020 01; 13(1):290-298. PMID: 31468725.
      View in: PubMed
    19. Li WJ, Jayakody LN, Franden MA, Wehrmann M, Daun T, Hauer B, Blank LM, Beckham GT, Klebensberger J, Wierckx N. Laboratory evolution reveals the metabolic and regulatory basis of ethylene glycol metabolism by Pseudomonas putida KT2440. Environ Microbiol. 2019 10; 21(10):3669-3682. PMID: 31166064.
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    20. Davis K, Rover MR, Salvachúa D, Smith RG, Beckham GT, Wen Z, Brown RC, Jarboe LR. Promoting microbial utilization of phenolic substrates from bio-oil. J Ind Microbiol Biotechnol. 2019 Nov; 46(11):1531-1545. PMID: 31270700.
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    21. Machovina MM, Mallinson SJB, Knott BC, Meyers AW, Garcia-Borràs M, Bu L, Gado JE, Oliver A, Schmidt GP, Hinchen DJ, Crowley MF, Johnson CW, Neidle EL, Payne CM, Houk KN, Beckham GT, McGeehan JE, DuBois JL. Enabling microbial syringol conversion through structure-guided protein engineering. Proc Natl Acad Sci U S A. 2019 07 09; 116(28):13970-13976. PMID: 31235604.
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    22. Elder T, Carlos Del Río J, Ralph J, Rencoret J, Kim H, Beckham GT. Radical coupling reactions of piceatannol and monolignols: A density functional theory study. Phytochemistry. 2019 Aug; 164:12-23. PMID: 31060026.
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    23. Anderson EM, Stone ML, Katahira R, Reed M, Muchero W, Ramirez KJ, Beckham GT, Román-Leshkov Y. Differences in S/G ratio in natural poplar variants do not predict catalytic depolymerization monomer yields. Nat Commun. 2019 05 02; 10(1):2033. PMID: 31048697.
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    24. Ciesielski PN, Wagner R, Bharadwaj VS, Killgore J, Mittal A, Beckham GT, Decker SR, Himmel ME, Crowley MF. Nanomechanics of cellulose deformation reveal molecular defects that facilitate natural deconstruction. Proc Natl Acad Sci U S A. 2019 05 14; 116(20):9825-9830. PMID: 31036649.
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    25. Jha RK, Narayanan N, Pandey N, Bingen JM, Kern TL, Johnson CW, Strauss CEM, Beckham GT, Hennelly SP, Dale T. Sensor-Enabled Alleviation of Product Inhibition in Chorismate Pyruvate-Lyase. ACS Synth Biol. 2019 04 19; 8(4):775-786. PMID: 30861344.
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    26. Zheng F, Vermaas JV, Zheng J, Wang Y, Tu T, Wang X, Xie X, Yao B, Beckham GT, Luo H. Activity and Thermostability of GH5 Endoglucanase Chimeras from Mesophilic and Thermophilic Parents. Appl Environ Microbiol. 2019 03 01; 85(5). PMID: 30552196.
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    27. Vermaas JV, Bentley GJ, Beckham GT, Crowley MF. Membrane Permeability of Terpenoids Explored with Molecular Simulation. J Phys Chem B. 2018 11 15; 122(45):10349-10361. PMID: 30352510.
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    28. Mallinson SJB, Machovina MM, Silveira RL, Garcia-Borràs M, Gallup N, Johnson CW, Allen MD, Skaf MS, Crowley MF, Neidle EL, Houk KN, Beckham GT, DuBois JL, McGeehan JE. A promiscuous cytochrome P450 aromatic O-demethylase for lignin bioconversion. Nat Commun. 2018 06 27; 9(1):2487. PMID: 29950589.
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    29. Tumen-Velasquez M, Johnson CW, Ahmed A, Dominick G, Fulk EM, Khanna P, Lee SA, Schmidt AL, Linger JG, Eiteman MA, Beckham GT, Neidle EL. Accelerating pathway evolution by increasing the gene dosage of chromosomal segments. Proc Natl Acad Sci U S A. 2018 07 03; 115(27):7105-7110. PMID: 29915086.
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    30. Franden MA, Jayakody LN, Li WJ, Wagner NJ, Cleveland NS, Michener WE, Hauer B, Blank LM, Wierckx N, Klebensberger J, Beckham GT. Engineering Pseudomonas putida KT2440 for efficient ethylene glycol utilization. Metab Eng. 2018 07; 48:197-207. PMID: 29885475.
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    31. Hanko EKR, Denby CM, Sànchez I Nogué V, Lin W, Ramirez KJ, Singer CA, Beckham GT, Keasling JD. Engineering ß-oxidation in Yarrowia lipolytica for methyl ketone production. Metab Eng. 2018 07; 48:52-62. PMID: 29852272.
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    32. Settle AE, Berstis L, Zhang S, Rorrer NA, Hu H, Richards RM, Beckham GT, Crowley MF, Vardon DR. Iodine-Catalyzed Isomerization of Dimethyl Muconate. ChemSusChem. 2018 Jun 11; 11(11):1768-1780. PMID: 29687956.
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    33. Deng W, Wang Y, Zhang S, Gupta KM, Hülsey MJ, Asakura H, Liu L, Han Y, Karp EM, Beckham GT, Dyson PJ, Jiang J, Tanaka T, Wang Y, Yan N. Catalytic amino acid production from biomass-derived intermediates. Proc Natl Acad Sci U S A. 2018 05 15; 115(20):5093-5098. PMID: 29712826.
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    34. Austin HP, Allen MD, Donohoe BS, Rorrer NA, Kearns FL, Silveira RL, Pollard BC, Dominick G, Duman R, El Omari K, Mykhaylyk V, Wagner A, Michener WE, Amore A, Skaf MS, Crowley MF, Thorne AW, Johnson CW, Woodcock HL, McGeehan JE, Beckham GT. Characterization and engineering of a plastic-degrading aromatic polyesterase. Proc Natl Acad Sci U S A. 2018 05 08; 115(19):E4350-E4357. PMID: 29666242.
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    35. Liu R, Liang L, Garst AD, Choudhury A, Nogué VSI, Beckham GT, Gill RT. Directed combinatorial mutagenesis of Escherichia coli for complex phenotype engineering. Metab Eng. 2018 05; 47:10-20. PMID: 29477855.
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    36. Taylor LE, Knott BC, Baker JO, Alahuhta PM, Hobdey SE, Linger JG, Lunin VV, Amore A, Subramanian V, Podkaminer K, Xu Q, VanderWall TA, Schuster LA, Chaudhari YB, Adney WS, Crowley MF, Himmel ME, Decker SR, Beckham GT. Engineering enhanced cellobiohydrolase activity. Nat Commun. 2018 03 22; 9(1):1186. PMID: 29567941.
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    37. Prates ET, Guan X, Li Y, Wang X, Chaffey PK, Skaf MS, Crowley MF, Tan Z, Beckham GT. The impact of O-glycan chemistry on the stability of intrinsically disordered proteins. Chem Sci. 2018 Apr 21; 9(15):3710-3715. PMID: 29780502.
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    38. Jha RK, Bingen JM, Johnson CW, Kern TL, Khanna P, Trettel DS, Strauss CEM, Beckham GT, Dale T. A protocatechuate biosensor for Pseudomonas putida KT2440 via promoter and protein evolution. Metab Eng Commun. 2018 Jun; 6:33-38. PMID: 29765865.
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    39. Amore A, Knott BC, Supekar NT, Shajahan A, Azadi P, Zhao P, Wells L, Linger JG, Hobdey SE, Vander Wall TA, Shollenberger T, Yarbrough JM, Tan Z, Crowley MF, Himmel ME, Decker SR, Beckham GT, Taylor LE. Distinct roles of N- and O-glycans in cellulase activity and stability. Proc Natl Acad Sci U S A. 2017 12 26; 114(52):13667-13672. PMID: 29229855.
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    40. Karp EM, Eaton TR, Sànchez I Nogué V, Vorotnikov V, Biddy MJ, Tan ECD, Brandner DG, Cywar RM, Liu R, Manker LP, Michener WE, Gilhespy M, Skoufa Z, Watson MJ, Fruchey OS, Vardon DR, Gill RT, Bratis AD, Beckham GT. Renewable acrylonitrile production. Science. 2017 12 08; 358(6368):1307-1310. PMID: 29217572.
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    41. Vermaas JV, Beckham GT, Crowley MF. Membrane Permeability of Fatty Acyl Compounds Studied via Molecular Simulation. J Phys Chem B. 2017 12 21; 121(50):11311-11324. PMID: 29040809.
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    42. Wang X, Salvachúa D, Sànchez I Nogué V, Michener WE, Bratis AD, Dorgan JR, Beckham GT. Propionic acid production from corn stover hydrolysate by Propionibacterium acidipropionici. Biotechnol Biofuels. 2017; 10:200. PMID: 28824710.
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    43. Guarnieri MT, Chou YC, Salvachúa D, Mohagheghi A, St John PC, Peterson DJ, Bomble YJ, Beckham GT. Metabolic Engineering of Actinobacillus succinogenes Provides Insights into Succinic Acid Biosynthesis. Appl Environ Microbiol. 2017 09 01; 83(17). PMID: 28625987.
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    44. Johnson CW, Abraham PE, Linger JG, Khanna P, Hettich RL, Beckham GT. Eliminating a global regulator of carbon catabolite repression enhances the conversion of aromatic lignin monomers to muconate in Pseudomonas putida KT2440. Metab Eng Commun. 2017 Dec; 5:19-25. PMID: 29188181.
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    45. Liang L, Liu R, Garst AD, Lee T, Nogué VSI, Beckham GT, Gill RT. CRISPR EnAbled Trackable genome Engineering for isopropanol production in Escherichia coli. Metab Eng. 2017 05; 41:1-10. PMID: 28216108.
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    46. Guarnieri MT, Ann Franden M, Johnson CW, Beckham GT. Conversion and assimilation of furfural and 5-(hydroxymethyl)furfural by Pseudomonas putida KT2440. Metab Eng Commun. 2017 Jun; 4:22-28. PMID: 29468129.
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    47. McMillan JD, Beckham GT. Thinking big: towards ideal strains and processes for large-scale aerobic biofuels production. Microb Biotechnol. 2017 01; 10(1):40-42. PMID: 28004888.
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    48. Elder T, Berstis L, Beckham GT, Crowley MF. Coupling and Reactions of 5-Hydroxyconiferyl Alcohol in Lignin Formation. J Agric Food Chem. 2016 Jun 15; 64(23):4742-50. PMID: 27236926.
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    49. Mayes HB, Knott BC, Crowley MF, Broadbelt LJ, Ståhlberg J, Beckham GT. Who's on base? Revealing the catalytic mechanism of inverting family 6 glycoside hydrolases. Chem Sci. 2016 Sep 01; 7(9):5955-5968. PMID: 30155195.
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    50. Hobdey SE, Knott BC, Haddad Momeni M, Taylor LE, Borisova AS, Podkaminer KK, VanderWall TA, Himmel ME, Decker SR, Beckham GT, Ståhlberg J. Biochemical and Structural Characterizations of Two Dictyostelium Cellobiohydrolases from the Amoebozoa Kingdom Reveal a High Level of Conservation between Distant Phylogenetic Trees of Life. Appl Environ Microbiol. 2016 06 01; 82(11):3395-409. PMID: 27037126.
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    51. Salvachúa D, Smith H, St John PC, Mohagheghi A, Peterson DJ, Black BA, Dowe N, Beckham GT. Succinic acid production from lignocellulosic hydrolysate by Basfia succiniciproducens. Bioresour Technol. 2016 Aug; 214:558-566. PMID: 27179951.
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    52. Johnson CW, Salvachúa D, Khanna P, Smith H, Peterson DJ, Beckham GT. Enhancing muconic acid production from glucose and lignin-derived aromatic compounds via increased protocatechuate decarboxylase activity. Metab Eng Commun. 2016 Dec; 3:111-119. PMID: 29468118.
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    53. Beckham GT, Johnson CW, Karp EM, Salvachúa D, Vardon DR. Opportunities and challenges in biological lignin valorization. Curr Opin Biotechnol. 2016 12; 42:40-53. PMID: 26974563.
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    54. Jana S, Hamre AG, Wildberger P, Holen MM, Eijsink VG, Beckham GT, Sørlie M, Payne CM. Aromatic-Mediated Carbohydrate Recognition in Processive Serratia marcescens Chitinases. J Phys Chem B. 2016 Feb 25; 120(7):1236-49. PMID: 26824449.
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    55. Salvachúa D, Mohagheghi A, Smith H, Bradfield MFA, Nicol W, Black BA, Biddy MJ, Dowe N, Beckham GT. Succinic acid production on xylose-enriched biorefinery streams by Actinobacillus succinogenes in batch fermentation. Biotechnol Biofuels. 2016; 9:28. PMID: 26839591.
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    56. Linger JG, Hobdey SE, Franden MA, Fulk EM, Beckham GT. Conversion of levoglucosan and cellobiosan by Pseudomonas putida KT2440. Metab Eng Commun. 2016 Dec; 3:24-29. PMID: 29468111.
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    57. Knott BC, Crowley MF, Himmel ME, Zimmer J, Beckham GT. Simulations of cellulose translocation in the bacterial cellulose synthase suggest a regulatory mechanism for the dimeric structure of cellulose. Chem Sci. 2016 May 01; 7(5):3108-3116. PMID: 27143998.
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    58. Berstis L, Beckham GT, Crowley MF. Electronic coupling through natural amino acids. J Chem Phys. 2015 Dec 14; 143(22):225102. PMID: 26671404.
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    59. Bradfield MF, Mohagheghi A, Salvachúa D, Smith H, Black BA, Dowe N, Beckham GT, Nicol W. Continuous succinic acid production by Actinobacillus succinogenes on xylose-enriched hydrolysate. Biotechnol Biofuels. 2015; 8:181. PMID: 26581168.
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    60. Cragg SM, Beckham GT, Bruce NC, Bugg TD, Distel DL, Dupree P, Etxabe AG, Goodell BS, Jellison J, McGeehan JE, McQueen-Mason SJ, Schnorr K, Walton PH, Watts JE, Zimmer M. Lignocellulose degradation mechanisms across the Tree of Life. Curr Opin Chem Biol. 2015 Dec; 29:108-19. PMID: 26583519.
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    61. Ferguson GA, Cheng L, Bu L, Kim S, Robichaud DJ, Nimlos MR, Curtiss LA, Beckham GT. Carbocation Stability in H-ZSM5 at High Temperature. J Phys Chem A. 2015 Nov 19; 119(46):11397-405. PMID: 26501585.
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    62. Greene ER, Himmel ME, Beckham GT, Tan Z. Glycosylation of Cellulases: Engineering Better Enzymes for Biofuels. Adv Carbohydr Chem Biochem. 2015; 72:63-112. PMID: 26613815.
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    63. Happs RM, Guan X, Resch MG, Davis MF, Beckham GT, Tan Z, Crowley MF. O-glycosylation effects on family 1 carbohydrate-binding module solution structures. FEBS J. 2015 Nov; 282(22):4341-56. PMID: 26307003.
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    64. Guan X, Chaffey PK, Zeng C, Greene ER, Chen L, Drake MR, Chen C, Groobman A, Resch MG, Himmel ME, Beckham GT, Tan Z. Molecular-scale features that govern the effects of O-glycosylation on a carbohydrate-binding module. Chem Sci. 2015 Dec 01; 6(12):7185-7189. PMID: 28966766.
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    65. Yuhara D, Barnes BC, Suh D, Knott BC, Beckham GT, Yasuoka K, Wu DT, Sum AK. Nucleation rate analysis of methane hydrate from molecular dynamics simulations. Faraday Discuss. 2015; 179:463-74. PMID: 25876773.
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    66. Kim S, Robichaud DJ, Beckham GT, Paton RS, Nimlos MR. Ethanol dehydration in HZSM-5 studied by density functional theory: evidence for a concerted process. J Phys Chem A. 2015 Apr 16; 119(15):3604-14. PMID: 25802969.
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    67. Vermaas JV, Crowley MF, Beckham GT, Payne CM. Effects of lytic polysaccharide monooxygenase oxidation on cellulose structure and binding of oxidized cellulose oligomers to cellulases. J Phys Chem B. 2015 May 21; 119(20):6129-43. PMID: 25785779.
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    68. Payne CM, Knott BC, Mayes HB, Hansson H, Himmel ME, Sandgren M, Ståhlberg J, Beckham GT. Fungal cellulases. Chem Rev. 2015 Feb 11; 115(3):1308-448. PMID: 25629559.
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    69. Johnson CW, Beckham GT. Aromatic catabolic pathway selection for optimal production of pyruvate and lactate from lignin. Metab Eng. 2015 Mar; 28:240-247. PMID: 25617773.
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    70. Barnes BC, Knott BC, Beckham GT, Wu DT, Sum AK. Reaction coordinate of incipient methane clathrate hydrate nucleation. J Phys Chem B. 2014 Nov 20; 118(46):13236-43. PMID: 25347748.
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    71. Linger JG, Vardon DR, Guarnieri MT, Karp EM, Hunsinger GB, Franden MA, Johnson CW, Chupka G, Strathmann TJ, Pienkos PT, Beckham GT. Lignin valorization through integrated biological funneling and chemical catalysis. Proc Natl Acad Sci U S A. 2014 Aug 19; 111(33):12013-8. PMID: 25092344.
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    72. Knott BC, Crowley MF, Himmel ME, Ståhlberg J, Beckham GT. Carbohydrate-protein interactions that drive processive polysaccharide translocation in enzymes revealed from a computational study of cellobiohydrolase processivity. J Am Chem Soc. 2014 Jun 18; 136(24):8810-9. PMID: 24869982.
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    73. Ragauskas AJ, Beckham GT, Biddy MJ, Chandra R, Chen F, Davis MF, Davison BH, Dixon RA, Gilna P, Keller M, Langan P, Naskar AK, Saddler JN, Tschaplinski TJ, Tuskan GA, Wyman CE. Lignin valorization: improving lignin processing in the biorefinery. Science. 2014 May 16; 344(6185):1246843. PMID: 24833396.
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    74. Gudmundsson M, Kim S, Wu M, Ishida T, Momeni MH, Vaaje-Kolstad G, Lundberg D, Royant A, Ståhlberg J, Eijsink VG, Beckham GT, Sandgren M. Structural and electronic snapshots during the transition from a Cu(II) to Cu(I) metal center of a lytic polysaccharide monooxygenase by X-ray photoreduction. J Biol Chem. 2014 Jul 04; 289(27):18782-92. PMID: 24828494.
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    75. Chen L, Drake MR, Resch MG, Greene ER, Himmel ME, Chaffey PK, Beckham GT, Tan Z. Specificity of O-glycosylation in enhancing the stability and cellulose binding affinity of Family 1 carbohydrate-binding modules. Proc Natl Acad Sci U S A. 2014 May 27; 111(21):7612-7. PMID: 24821760.
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    76. Barnes BC, Beckham GT, Wu DT, Sum AK. Two-component order parameter for quantifying clathrate hydrate nucleation and growth. J Chem Phys. 2014 Apr 28; 140(16):164506. PMID: 24784286.
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    77. Ito T, Saikawa K, Kim S, Fujita K, Ishiwata A, Kaeothip S, Arakawa T, Wakagi T, Beckham GT, Ito Y, Fushinobu S. Crystal structure of glycoside hydrolase family 127 ß-l-arabinofuranosidase from Bifidobacterium longum. Biochem Biophys Res Commun. 2014 Apr 25; 447(1):32-7. PMID: 24680821.
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    78. Nordwald EM, Brunecky R, Himmel ME, Beckham GT, Kaar JL. Charge engineering of cellulases improves ionic liquid tolerance and reduces lignin inhibition. Biotechnol Bioeng. 2014 Aug; 111(8):1541-9. PMID: 24522957.
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    79. Mayes HB, Broadbelt LJ, Beckham GT. How sugars pucker: electronic structure calculations map the kinetic landscape of five biologically paramount monosaccharides and their implications for enzymatic catalysis. J Am Chem Soc. 2014 Jan 22; 136(3):1008-22. PMID: 24368073.
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    80. Lloyd RE, Streeter SD, Foster PG, Littlewood DT, Huntley J, Beckham GT, Himmel ME, Cragg SM. The complete mitochondrial genome of Limnoria quadripunctata Holthuis (Isopoda: Limnoriidae). Mitochondrial DNA. 2015; 26(6):825-6. PMID: 24409843.
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    81. Beckham GT, Ståhlberg J, Knott BC, Himmel ME, Crowley MF, Sandgren M, Sørlie M, Payne CM. Towards a molecular-level theory of carbohydrate processivity in glycoside hydrolases. Curr Opin Biotechnol. 2014 Jun; 27:96-106. PMID: 24863902.
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    82. Mayes HB, Tian J, Nolte MW, Shanks BH, Beckham GT, Gnanakaran S, Broadbelt LJ. Sodium ion interactions with aqueous glucose: insights from quantum mechanics, molecular dynamics, and experiment. J Phys Chem B. 2014 Feb 27; 118(8):1990-2000. PMID: 24308866.
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    83. Knott BC, Haddad Momeni M, Crowley MF, Mackenzie LF, Götz AW, Sandgren M, Withers SG, Ståhlberg J, Beckham GT. The mechanism of cellulose hydrolysis by a two-step, retaining cellobiohydrolase elucidated by structural and transition path sampling studies. J Am Chem Soc. 2014 Jan 08; 136(1):321-9. PMID: 24341799.
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    84. Kim S, Ståhlberg J, Sandgren M, Paton RS, Beckham GT. Quantum mechanical calculations suggest that lytic polysaccharide monooxygenases use a copper-oxyl, oxygen-rebound mechanism. Proc Natl Acad Sci U S A. 2014 Jan 07; 111(1):149-54. PMID: 24344312.
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    85. Payne CM, Jiang W, Shirts MR, Himmel ME, Crowley MF, Beckham GT. Glycoside hydrolase processivity is directly related to oligosaccharide binding free energy. J Am Chem Soc. 2013 Dec 18; 135(50):18831-9. PMID: 24279927.
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    86. Beckham G, Mizuguchi S, Carter C, Sato K, Ramsey M, Lamont H, Hornsby G, Haff G, Stone M. Relationships of isometric mid-thigh pull variables to weightlifting performance. J Sports Med Phys Fitness. 2013 Oct; 53(5):573-81. PMID: 23903539.
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    87. Wu M, Bu L, Vuong TV, Wilson DB, Crowley MF, Sandgren M, Ståhlberg J, Beckham GT, Hansson H. Loop motions important to product expulsion in the Thermobifida fusca glycoside hydrolase family 6 cellobiohydrolase from structural and computational studies. J Biol Chem. 2013 Nov 15; 288(46):33107-17. PMID: 24085303.
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    88. Dai Z, Aryal UK, Shukla A, Qian WJ, Smith RD, Magnuson JK, Adney WS, Beckham GT, Brunecky R, Himmel ME, Decker SR, Ju X, Zhang X, Baker SE. Impact of alg3 gene deletion on growth, development, pigment production, protein secretion, and functions of recombinant Trichoderma reesei cellobiohydrolases in Aspergillus niger. Fungal Genet Biol. 2013 Dec; 61:120-32. PMID: 24076077.
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    89. Lin Y, Beckham GT, Himmel ME, Crowley MF, Chu JW. Endoglucanase peripheral loops facilitate complexation of glucan chains on cellulose via adaptive coupling to the emergent substrate structures. J Phys Chem B. 2013 Sep 19; 117(37):10750-8. PMID: 23972069.
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    90. Ciesielski PN, Matthews JF, Tucker MP, Beckham GT, Crowley MF, Himmel ME, Donohoe BS. 3D electron tomography of pretreated biomass informs atomic modeling of cellulose microfibrils. ACS Nano. 2013 Sep 24; 7(9):8011-9. PMID: 23988022.
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    91. Payne CM, Resch MG, Chen L, Crowley MF, Himmel ME, Taylor LE, Sandgren M, Ståhlberg J, Stals I, Tan Z, Beckham GT. Glycosylated linkers in multimodular lignocellulose-degrading enzymes dynamically bind to cellulose. Proc Natl Acad Sci U S A. 2013 Sep 03; 110(36):14646-51. PMID: 23959893.
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    92. Kern M, McGeehan JE, Streeter SD, Martin RN, Besser K, Elias L, Eborall W, Malyon GP, Payne CM, Himmel ME, Schnorr K, Beckham GT, Cragg SM, Bruce NC, McQueen-Mason SJ. Structural characterization of a unique marine animal family 7 cellobiohydrolase suggests a mechanism of cellulase salt tolerance. Proc Natl Acad Sci U S A. 2013 Jun 18; 110(25):10189-94. PMID: 23733951.
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    93. Taylor CB, Payne CM, Himmel ME, Crowley MF, McCabe C, Beckham GT. Binding site dynamics and aromatic-carbohydrate interactions in processive and non-processive family 7 glycoside hydrolases. J Phys Chem B. 2013 May 02; 117(17):4924-33. PMID: 23534900.
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    94. Wu M, Beckham GT, Larsson AM, Ishida T, Kim S, Payne CM, Himmel ME, Crowley MF, Horn SJ, Westereng B, Igarashi K, Samejima M, Ståhlberg J, Eijsink VG, Sandgren M. Crystal structure and computational characterization of the lytic polysaccharide monooxygenase GH61D from the Basidiomycota fungus Phanerochaete chrysosporium. J Biol Chem. 2013 May 03; 288(18):12828-39. PMID: 23525113.
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    95. Bu L, Crowley MF, Himmel ME, Beckham GT. Computational investigation of the pH dependence of loop flexibility and catalytic function in glycoside hydrolases. J Biol Chem. 2013 Apr 26; 288(17):12175-86. PMID: 23504310.
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    96. Ghattyvenkatakrishna PK, Alekozai EM, Beckham GT, Schulz R, Crowley MF, Uberbacher EC, Cheng X. Initial recognition of a cellodextrin chain in the cellulose-binding tunnel may affect cellobiohydrolase directional specificity. Biophys J. 2013 Feb 19; 104(4):904-12. PMID: 23442969.
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    97. Momeni MH, Payne CM, Hansson H, Mikkelsen NE, Svedberg J, Engström Å, Sandgren M, Beckham GT, Ståhlberg J. Structural, biochemical, and computational characterization of the glycoside hydrolase family 7 cellobiohydrolase of the tree-killing fungus Heterobasidion irregulare. J Biol Chem. 2013 Feb 22; 288(8):5861-72. PMID: 23303184.
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    98. Sammond DW, Payne CM, Brunecky R, Himmel ME, Crowley MF, Beckham GT. Cellulase linkers are optimized based on domain type and function: insights from sequence analysis, biophysical measurements, and molecular simulation. PLoS One. 2012; 7(11):e48615. PMID: 23139804.
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    99. Payne CM, Baban J, Horn SJ, Backe PH, Arvai AS, Dalhus B, Bjørås M, Eijsink VG, Sørlie M, Beckham GT, Vaaje-Kolstad G. Hallmarks of processivity in glycoside hydrolases from crystallographic and computational studies of the Serratia marcescens chitinases. J Biol Chem. 2012 Oct 19; 287(43):36322-30. PMID: 22952223.
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    100. Bu L, Nimlos MR, Shirts MR, Ståhlberg J, Himmel ME, Crowley MF, Beckham GT. Product binding varies dramatically between processive and nonprocessive cellulase enzymes. J Biol Chem. 2012 Jul 13; 287(29):24807-13. PMID: 22648408.
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    101. Vicari KJ, Tallam SS, Shatova T, Joo KK, Scarlata CJ, Humbird D, Wolfrum EJ, Beckham GT. Uncertainty in techno-economic estimates of cellulosic ethanol production due to experimental measurement uncertainty. Biotechnol Biofuels. 2012 Apr 17; 5(1):23. PMID: 22507382.
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    102. Nimlos MR, Beckham GT, Matthews JF, Bu L, Himmel ME, Crowley MF. Binding preferences, surface attachment, diffusivity, and orientation of a family 1 carbohydrate-binding module on cellulose. J Biol Chem. 2012 Jun 08; 287(24):20603-12. PMID: 22496371.
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    103. Matthews JF, Beckham GT, Bergenstråhle-Wohlert M, Brady JW, Himmel ME, Crowley MF. Comparison of Cellulose Iß Simulations with Three Carbohydrate Force Fields. J Chem Theory Comput. 2012 Feb 14; 8(2):735-48. PMID: 26596620.
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    104. Beckham GT, Dai Z, Matthews JF, Momany M, Payne CM, Adney WS, Baker SE, Himmel ME. Harnessing glycosylation to improve cellulase activity. Curr Opin Biotechnol. 2012 Jun; 23(3):338-45. PMID: 22186222.
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    105. Taylor CB, Talib MF, McCabe C, Bu L, Adney WS, Himmel ME, Crowley MF, Beckham GT. Computational investigation of glycosylation effects on a family 1 carbohydrate-binding module. J Biol Chem. 2012 Jan 27; 287(5):3147-55. PMID: 22147693.
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    106. Walsh MR, Rainey JD, Lafond PG, Park DH, Beckham GT, Jones MD, Lee KH, Koh CA, Sloan ED, Wu DT, Sum AK. The cages, dynamics, and structuring of incipient methane clathrate hydrates. Phys Chem Chem Phys. 2011 Nov 28; 13(44):19951-9. PMID: 21997437.
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    107. Payne CM, Bomble YJ, Taylor CB, McCabe C, Himmel ME, Crowley MF, Beckham GT. Multiple functions of aromatic-carbohydrate interactions in a processive cellulase examined with molecular simulation. J Biol Chem. 2011 Nov 25; 286(47):41028-35. PMID: 21965672.
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    108. Lin Y, Silvestre-Ryan J, Himmel ME, Crowley MF, Beckham GT, Chu JW. Protein allostery at the solid-liquid interface: endoglucanase attachment to cellulose affects glucan clenching in the binding cleft. J Am Chem Soc. 2011 Oct 19; 133(41):16617-24. PMID: 21877736.
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    109. Hynninen AP, Matthews JF, Beckham GT, Crowley MF, Nimlos MR. Coarse-Grain Model for Glucose, Cellobiose, and Cellotetraose in Water. J Chem Theory Comput. 2011 Jul 12; 7(7):2137-50. PMID: 26606485.
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    110. Beckham GT, Peters B. Optimizing Nucleus Size Metrics for Liquid-Solid Nucleation from Transition Paths of Near-Nanosecond Duration. J Phys Chem Lett. 2011 May 19; 2(10):1133-8. PMID: 26295315.
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    111. Beckham GT, Crowley MF. Examination of the a-chitin structure and decrystallization thermodynamics at the nanoscale. J Phys Chem B. 2011 Apr 21; 115(15):4516-22. PMID: 21452798.
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    112. Bu L, Beckham GT, Shirts MR, Nimlos MR, Adney WS, Himmel ME, Crowley MF. Probing carbohydrate product expulsion from a processive cellulase with multiple absolute binding free energy methods. J Biol Chem. 2011 May 20; 286(20):18161-9. PMID: 21454590.
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    113. Beckham GT, Matthews JF, Peters B, Bomble YJ, Himmel ME, Crowley MF. Molecular-level origins of biomass recalcitrance: decrystallization free energies for four common cellulose polymorphs. J Phys Chem B. 2011 Apr 14; 115(14):4118-27. PMID: 21425804.
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    114. Matthews JF, Bergenstråhle M, Beckham GT, Himmel ME, Nimlos MR, Brady JW, Crowley MF. High-temperature behavior of cellulose I. J Phys Chem B. 2011 Mar 17; 115(10):2155-66. PMID: 21338135.
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    115. Chundawat SP, Beckham GT, Himmel ME, Dale BE. Deconstruction of lignocellulosic biomass to fuels and chemicals. Annu Rev Chem Biomol Eng. 2011; 2:121-45. PMID: 22432613.
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    116. Beckham GT, Bomble YJ, Bayer EA, Himmel ME, Crowley MF. Applications of computational science for understanding enzymatic deconstruction of cellulose. Curr Opin Biotechnol. 2011 Apr; 22(2):231-8. PMID: 21168322.
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    117. Beckham GT, Bomble YJ, Matthews JF, Taylor CB, Resch MG, Yarbrough JM, Decker SR, Bu L, Zhao X, McCabe C, Wohlert J, Bergenstråhle M, Brady JW, Adney WS, Himmel ME, Crowley MF. The O-glycosylated linker from the Trichoderma reesei Family 7 cellulase is a flexible, disordered protein. Biophys J. 2010 Dec 01; 99(11):3773-81. PMID: 21112302.
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    118. Bomble YJ, Beckham GT, Matthews JF, Nimlos MR, Himmel ME, Crowley MF. Modeling the self-assembly of the cellulosome enzyme complex. J Biol Chem. 2011 Feb 18; 286(7):5614-23. PMID: 21098021.
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    119. Beckham GT, Matthews JF, Bomble YJ, Bu L, Adney WS, Himmel ME, Nimlos MR, Crowley MF. Identification of amino acids responsible for processivity in a Family 1 carbohydrate-binding module from a fungal cellulase. J Phys Chem B. 2010 Jan 28; 114(3):1447-53. PMID: 20050714.
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    120. Bu L, Beckham GT, Crowley MF, Chang CH, Matthews JF, Bomble YJ, Adney WS, Himmel ME, Nimlos MR. The energy landscape for the interaction of the family 1 carbohydrate-binding module and the cellulose surface is altered by hydrolyzed glycosidic bonds. J Phys Chem B. 2009 Aug 06; 113(31):10994-1002. PMID: 19594145.
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    121. Peters B, Zimmermann NE, Beckham GT, Tester JW, Trout BL. Path sampling calculation of methane diffusivity in natural gas hydrates from a water-vacancy assisted mechanism. J Am Chem Soc. 2008 Dec 24; 130(51):17342-50. PMID: 19053189.
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    122. Beckham GT, Peters B, Trout BL. Evidence for a size dependent nucleation mechanism in solid state polymorph transformations. J Phys Chem B. 2008 Jun 26; 112(25):7460-6. PMID: 18528974.
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    123. Peters B, Beckham GT, Trout BL. Extensions to the likelihood maximization approach for finding reaction coordinates. J Chem Phys. 2007 Jul 21; 127(3):034109. PMID: 17655433.
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    124. Beckham GT, Peters B, Starbuck C, Variankaval N, Trout BL. Surface-mediated nucleation in the solid-state polymorph transformation of terephthalic acid. J Am Chem Soc. 2007 Apr 18; 129(15):4714-23. PMID: 17385859.
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