Colorado PROFILES, The Colorado Clinical and Translational Sciences Institute (CCTSI)
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Jeffrey Lawrence Bennett

TitleProfessor
InstitutionUniversity of Colorado Denver - Anschutz Medical Campus
DepartmentSOM-Neurology
Phone303/724-2184

    Collapse Research 
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    K08EY000387     (BENNETT, JEFFREY L)Jul 1, 1998 - Jun 30, 2003
    NIH/NEI
    GROWTH FACTORS IN MAMMALIAN EYE DEVELOPMENT
    Role: Principal Investigator

    R03EY014573     (BENNETT, JEFFREY L)Apr 1, 2004 - Mar 31, 2008
    NIH/NEI
    Antigen Identification in Occult Chorioretinopathies
    Role: Principal Investigator

    R01EY022936     (BENNETT, JEFFREY L)Jan 1, 2013 - Dec 31, 2017
    NIH/NEI
    Humoral Immunity, Astrocyte Injury, and Demyelination in Neuromyelitis Optica
    Role: Principal Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Peschl P, Schanda K, Zeka B, Given K, Böhm D, Ruprecht K, Saiz A, Lutterotti A, Rostásy K, Höftberger R, Berger T, Macklin W, Lassmann H, Bradl M, Bennett JL, Reindl M. Human antibodies against the myelin oligodendrocyte glycoprotein can cause complement-dependent demyelination. J Neuroinflammation. 2017 Oct 25; 14(1):208. PMID: 29070051.
      View in: PubMed
    2. Bennett JL, Owens GP. Neuromyelitis Optica: Deciphering a Complex Immune-Mediated Astrocytopathy. J Neuroophthalmol. 2017 Sep; 37(3):291-299. PMID: 28410278.
      View in: PubMed
    3. Shimizu F, Schaller KL, Owens GP, Cotleur AC, Kellner D, Takeshita Y, Obermeier B, Kryzer TJ, Sano Y, Kanda T, Lennon VA, Ransohoff RM, Bennett JL. Glucose-regulated protein 78 autoantibody associates with blood-brain barrier disruption in neuromyelitis optica. Sci Transl Med. 2017 Jul 05; 9(397). PMID: 28679661.
      View in: PubMed
    4. Kowarik MC, Astling D, Gasperi C, Wemlinger S, Schumann H, Dzieciatkowska M, Ritchie AM, Hemmer B, Owens GP, Bennett JL. CNS Aquaporin-4-specific B cells connect with multiple B-cell compartments in neuromyelitis optica spectrum disorder. Ann Clin Transl Neurol. 2017 Jun; 4(6):369-380. PMID: 28589164.
      View in: PubMed
    5. Alberga D, Trisciuzzi D, Lattanzi G, Bennett JL, Verkman AS, Mangiatordi GF, Nicolotti O. Comparative molecular dynamics study of neuromyelitis optica-immunoglobulin G binding to aquaporin-4 extracellular domains. Biochim Biophys Acta. 2017 08; 1859(8):1326-1334. PMID: 28477975.
      View in: PubMed
    6. Rodríguez-Colón G, Bratton EM, Serracino H, Bennett JL, Hink EM. Sphenoid Wing Meningioma With Extraocular Muscle Involvement Mimicking Idiopathic Orbital Inflammation. Ophthal Plast Reconstr Surg. 2017 May/Jun; 33(3S Suppl 1):S97-S99. PMID: 26882057.
      View in: PubMed
    7. Soltys JN, Meyer SA, Schumann H, Gibson EA, Restrepo D, Bennett JL. Determining the Spatial Relationship of Membrane-Bound Aquaporin-4 Autoantibodies by STED Nanoscopy. Biophys J. 2017 Apr 25; 112(8):1692-1702. PMID: 28445760.
      View in: PubMed
    8. Liu Y, Given KS, Harlow DE, Matschulat AM, Macklin WB, Bennett JL, Owens GP. Myelin-specific multiple sclerosis antibodies cause complement-dependent oligodendrocyte loss and demyelination. Acta Neuropathol Commun. 2017 Mar 24; 5(1):25. PMID: 28340598.
      View in: PubMed
    9. Vogel AL, Knier B, Lammens K, Kalluri SR, Kuhlmann T, Bennett JL, Korn T. Deletional tolerance prevents AQP4-directed autoimmunity in mice. Eur J Immunol. 2017 Mar; 47(3):458-469. PMID: 28058717.
      View in: PubMed
    10. Sagan SA, Winger RC, Cruz-Herranz A, Nelson PA, Hagberg S, Miller CN, Spencer CM, Ho PP, Bennett JL, Levy M, Levin MH, Verkman AS, Steinman L, Green AJ, Anderson MS, Sobel RA, Zamvil SS. Tolerance checkpoint bypass permits emergence of pathogenic T cells to neuromyelitis optica autoantigen aquaporin-4. Proc Natl Acad Sci U S A. 2016 Dec 20; 113(51):14781-14786. PMID: 27940915.
      View in: PubMed
    11. Liu Y, Harlow DE, Given KS, Owens GP, Macklin WB, Bennett JL. Variable sensitivity to complement-dependent cytotoxicity in murine models of neuromyelitis optica. J Neuroinflammation. 2016 Dec 01; 13(1):301. PMID: 27905992.
      View in: PubMed
    12. Kumpe DA, Seinfeld J, Huang X, Mei Q, Case DE, Roark CD, Subramanian PS, Lind KE, Pelak VS, Bennett JL. Dural sinus stenting for idiopathic intracranial hypertension: factors associated with hemodynamic failure and management with extended stenting. J Neurointerv Surg. 2017 Sep; 9(9):867-874. PMID: 27935482.
      View in: PubMed
    13. Bennett JL. Finding NMO: The Evolving Diagnostic Criteria of Neuromyelitis Optica. J Neuroophthalmol. 2016 Sep; 36(3):238-45. PMID: 27529327.
      View in: PubMed
    14. Grünewald B, Bennett JL, Toyka KV, Sommer C, Geis C. Efficacy of Polyvalent Human Immunoglobulins in an Animal Model of Neuromyelitis Optica Evoked by Intrathecal Anti-Aquaporin 4 Antibodies. Int J Mol Sci. 2016 Aug 26; 17(9). PMID: 27571069.
      View in: PubMed
    15. Weil MT, Möbius W, Winkler A, Ruhwedel T, Wrzos C, Romanelli E, Bennett JL, Enz L, Goebels N, Nave KA, Kerschensteiner M, Schaeren-Wiemers N, Stadelmann C, Simons M. Loss of Myelin Basic Protein Function Triggers Myelin Breakdown in Models of Demyelinating Diseases. Cell Rep. 2016 Jul 12; 16(2):314-22. PMID: 27346352; PMCID: PMC4949381.
    16. Herwerth M, Kalluri SR, Srivastava R, Kleele T, Kenet S, Illes Z, Merkler D, Bennett JL, Misgeld T, Hemmer B. In vivo imaging reveals rapid astrocyte depletion and axon damage in a model of neuromyelitis optica-related pathology. Ann Neurol. 2016 Mar 06. PMID: 26946517.
      View in: PubMed
    17. Yan Y, Li Y, Fu Y, Yang L, Su L, Shi K, Li M, Liu Q, Borazanci A, Liu Y, He Y, Bennett JL, Vollmer TL, Shi FD. Autoantibody to MOG suggests two distinct clinical subtypes of NMOSD. Sci China Life Sci. 2016 Dec; 59(12):1270-1281. PMID: 26920678.
      View in: PubMed
    18. Cree BA, Bennett JL, Sheehan M, Cohen J, Hartung HP, Aktas O, Kim HJ, Paul F, Pittock S, Weinshenker B, Wingerchuk D, Fujihara K, Cutter G, Patra K, Flor A, Barron G, Madani S, Ratchford JN, Katz E. Placebo-controlled study in neuromyelitis optica-Ethical and design considerations. Mult Scler. 2016 Jun; 22(7):862-72. PMID: 26666258; PMCID: PMC4904355.
    19. Blauth K, Owens GP, Bennett JL. The Ins and Outs of B Cells in Multiple Sclerosis. Front Immunol. 2015; 6:565. PMID: 26594215; PMCID: PMC4633507.
    20. Nagel MA, White T, Khmeleva N, Rempel A, Boyer PJ, Bennett JL, Haller A, Lear-Kaul K, Kandasmy B, Amato M, Wood E, Durairaj V, Fogt F, Tamhankar MA, Grossniklaus HE, Poppiti RJ, Bockelman B, Keyvani K, Pollak L, Mendlovic S, Fowkes M, Eberhart CG, Buttmann M, Toyka KV, Meyer-ter-Vehn T, Petursdottir V, Gilden D. Analysis of Varicella-Zoster Virus in Temporal Arteries Biopsy Positive and Negative for Giant Cell Arteritis. JAMA Neurol. 2015 Nov; 72(11):1281-7. PMID: 26349037.
      View in: PubMed
    21. Blauth K, Soltys J, Matschulat A, Reiter CR, Ritchie A, Baird NL, Bennett JL, Owens GP. Antibodies produced by clonally expanded plasma cells in multiple sclerosis cerebrospinal fluid cause demyelination of spinal cord explants. Acta Neuropathol. 2015 Dec; 130(6):765-81. PMID: 26511623; PMCID: PMC4655138 [Available on 12/01/16].
    22. Melamed E, Levy M, Waters PJ, Sato DK, Bennett JL, John GR, Hooper DC, Saiz A, Bar-Or A, Kim HJ, Pandit L, Leite MI, Asgari N, Kissani N, Hintzen R, Marignier R, Jarius S, Marcelletti J, Smith TJ, Yeaman MR, Han MH, Aktas O, Apiwattanakul M, Banwell B, Bichuetti D, Broadley S, Cabre P, Chitnis T, De Seze J, Fujihara K, Greenberg B, Hellwig K, Iorio R, Jarius S, Klawiter E, Kleiter I, Lana-Peixoto M, O'Connor K, Palace J, Paul F, Prayoonwiwat N, Ruprecht K, Stuve O, Tedder T, Tenembaum S, Garrahan JP, Aires B, van Herle K, van Pelt D, Villoslada P, Waubant E, Weinshenker B, Wingerchuk D, Würfel J, Zamvil S. Update on biomarkers in neuromyelitis optica. Neurol Neuroimmunol Neuroinflamm. 2015 Aug; 2(4):e134. PMID: 26236760; PMCID: PMC4516398.
    23. Kremer S, Renard F, Achard S, Lana-Peixoto MA, Palace J, Asgari N, Klawiter EC, Tenembaum SN, Banwell B, Greenberg BM, Bennett JL, Levy M, Villoslada P, Saiz A, Fujihara K, Chan KH, Schippling S, Paul F, Kim HJ, de Seze J, Wuerfel JT, Cabre P, Marignier R, Tedder T, van Pelt D, Broadley S, Chitnis T, Wingerchuk D, Pandit L, Leite MI, Apiwattanakul M, Kleiter I, Prayoonwiwat N, Han M, Hellwig K, van Herle K, John G, Hooper DC, Nakashima I, Sato D, Yeaman MR, Waubant E, Zamvil S, Stüve O, Aktas O, Smith TJ, Jacob A, O'Connor K. Use of Advanced Magnetic Resonance Imaging Techniques in Neuromyelitis Optica Spectrum Disorder. JAMA Neurol. 2015 Jul; 72(7):815-22. PMID: 26010909; PMCID: PMC4828237.
    24. Wingerchuk DM, Banwell B, Bennett JL, Cabre P, Carroll W, Chitnis T, de Seze J, Fujihara K, Greenberg B, Jacob A, Jarius S, Lana-Peixoto M, Levy M, Simon JH, Tenembaum S, Traboulsee AL, Waters P, Wellik KE, Weinshenker BG. International consensus diagnostic criteria for neuromyelitis optica spectrum disorders. Neurology. 2015 Jul 14; 85(2):177-89. PMID: 26092914; PMCID: PMC4515040.
    25. Golas L, Bennett JL, White TM, Skarf B, Lesser R, Nagel MA, Gilden D. Varicella Zoster Virus in Ischemic Optic Neuropathy. Ophthalmology. 2015 Oct; 122(10):2142-5. PMID: 26050536; PMCID: PMC4581904 [Available on 10/01/16].
    26. Bennett JL, O'Connor KC, Bar-Or A, Zamvil SS, Hemmer B, Tedder TF, von Büdingen HC, Stuve O, Yeaman MR, Smith TJ, Stadelmann C. B lymphocytes in neuromyelitis optica. Neurol Neuroimmunol Neuroinflamm. 2015 Jun; 2(3):e104. PMID: 25977932; PMCID: PMC4426682.
    27. Owens GP, Ritchie A, Rossi A, Schaller K, Wemlinger S, Schumann H, Shearer A, Verkman AS, Bennett JL. Mutagenesis of the aquaporin 4 extracellular domains defines restricted binding patterns of pathogenic neuromyelitis optica IgG. J Biol Chem. 2015 May 08; 290(19):12123-34. PMID: 25792738; PMCID: PMC4424347.
    28. Gilden D, White T, Khmeleva N, Heintzman A, Choe A, Boyer PJ, Grose C, Carpenter JE, Rempel A, Bos N, Kandasamy B, Lear-Kaul K, Holmes DB, Bennett JL, Cohrs RJ, Mahalingam R, Mandava N, Eberhart CG, Bockelman B, Poppiti RJ, Tamhankar MA, Fogt F, Amato M, Wood E, Durairaj V, Rasmussen S, Petursdottir V, Pollak L, Mendlovic S, Chatelain D, Keyvani K, Brueck W, Nagel MA. Prevalence and distribution of VZV in temporal arteries of patients with giant cell arteritis. Neurology. 2015 May 12; 84(19):1948-55. PMID: 25695965; PMCID: PMC4433460.
    29. Sergott RC, Bennett JL, Rieckmann P, Montalban X, Mikol D, Freudensprung U, Plitz T, van Beek J. ATON: results from a Phase II randomized trial of the B-cell-targeting agent atacicept in patients with optic neuritis. J Neurol Sci. 2015 Apr 15; 351(1-2):174-8. PMID: 25758472.
      View in: PubMed
    30. Kowarik MC, Dzieciatkowska M, Wemlinger S, Ritchie AM, Hemmer B, Owens GP, Bennett JL. The cerebrospinal fluid immunoglobulin transcriptome and proteome in neuromyelitis optica reveals central nervous system-specific B cell populations. J Neuroinflammation. 2015 Jan 28; 12:19. PMID: 25626447; PMCID: PMC4323273.
    31. Geis C, Ritter C, Ruschil C, Weishaupt A, Grünewald B, Stoll G, Holmoy T, Misu T, Fujihara K, Hemmer B, Stadelmann C, Bennett JL, Sommer C, Toyka KV. The intrinsic pathogenic role of autoantibodies to aquaporin 4 mediating spinal cord disease in a rat passive-transfer model. Exp Neurol. 2015 Mar; 265:8-21. PMID: 25542977; PMCID: PMC4382207.
    32. Bennett JL, Nickerson M, Costello F, Sergott RC, Calkwood JC, Galetta SL, Balcer LJ, Markowitz CE, Vartanian T, Morrow M, Moster ML, Taylor AW, Pace TW, Frohman T, Frohman EM. Re-evaluating the treatment of acute optic neuritis. J Neurol Neurosurg Psychiatry. 2015 Jul; 86(7):799-808. PMID: 25355373; PMCID: PMC4414747.
    33. Papadopoulos MC, Bennett JL, Verkman AS. Treatment of neuromyelitis optica: state-of-the-art and emerging therapies. Nat Rev Neurol. 2014 Sep; 10(9):493-506. PMID: 25112508; PMCID: PMC4229040.
    34. Waters PJ, Pittock SJ, Bennett JL, Jarius S, Weinshenker BG, Wingerchuk DM. Evaluation of aquaporin-4 antibody assays. Clin Exp Neuroimmunol. 2014 Oct; 5(3):290-303. PMID: 27840658.
      View in: PubMed
    35. Saadoun S, Waters P, Owens GP, Bennett JL, Vincent A, Papadopoulos MC. Neuromyelitis optica MOG-IgG causes reversible lesions in mouse brain. Acta Neuropathol Commun. 2014 Mar 31; 2:35. PMID: 24685353; PMCID: PMC3977893.
    36. Kowarik MC, Soltys J, Bennett JL. The treatment of neuromyelitis optica. J Neuroophthalmol. 2014 Mar; 34(1):70-82. PMID: 24531318; PMCID: PMC4208473.
    37. Asavapanumas N, Ratelade J, Papadopoulos MC, Bennett JL, Levin MH, Verkman AS. Experimental mouse model of optic neuritis with inflammatory demyelination produced by passive transfer of neuromyelitis optica-immunoglobulin G. J Neuroinflammation. 2014 Jan 27; 11:16. PMID: 24468108; PMCID: PMC3909205.
    38. Wrzos C, Winkler A, Metz I, Kayser DM, Thal DR, Wegner C, Brück W, Nessler S, Bennett JL, Stadelmann C. Early loss of oligodendrocytes in human and experimental neuromyelitis optica lesions. Acta Neuropathol. 2014 Apr; 127(4):523-38. PMID: 24292009; PMCID: PMC4229038.
    39. Ratelade J, Asavapanumas N, Ritchie AM, Wemlinger S, Bennett JL, Verkman AS. Involvement of antibody-dependent cell-mediated cytotoxicity in inflammatory demyelination in a mouse model of neuromyelitis optica. Acta Neuropathol. 2013 Nov; 126(5):699-709. PMID: 23995423; PMCID: PMC3890328.
    40. Saadoun S, Waters P, Leite MI, Bennett JL, Vincent A, Papadopoulos MC. Neuromyelitis optica IgG causes placental inflammation and fetal death. J Immunol. 2013 Sep 15; 191(6):2999-3005. PMID: 23935196; PMCID: PMC4161708.
    41. Nagel MA, Bennett JL, Khmeleva N, Choe A, Rempel A, Boyer PJ, Gilden D. Multifocal VZV vasculopathy with temporal artery infection mimics giant cell arteritis. Neurology. 2013 May 28; 80(22):2017-21. PMID: 23635966; PMCID: PMC3716402.
    42. Levin MH, Bennett JL, Verkman AS. Optic neuritis in neuromyelitis optica. Prog Retin Eye Res. 2013 Sep; 36:159-71. PMID: 23545439; PMCID: PMC3770284.
    43. Raveendra BL, Wu H, Baccala R, Reddy MM, Schilke J, Bennett JL, Theofilopoulos AN, Kodadek T. Discovery of peptoid ligands for anti-aquaporin 4 antibodies. Chem Biol. 2013 Mar 21; 20(3):351-9. PMID: 23521793; PMCID: PMC3640264.
    44. Mathias M, Nagel MA, Khmeleva N, Boyer PJ, Choe A, Durairaj VD, Bennett JL, Mandava N, Gilden D. VZV multifocal vasculopathy with ischemic optic neuropathy, acute retinal necrosis and temporal artery infection in the absence of zoster rash. J Neurol Sci. 2013 Feb 15; 325(1-2):180-2. PMID: 23312850; PMCID: PMC3586992.
    45. Phuan PW, Anderson MO, Tradtrantip L, Zhang H, Tan J, Lam C, Bennett JL, Verkman AS. A small-molecule screen yields idiotype-specific blockers of neuromyelitis optica immunoglobulin G binding to aquaporin-4. J Biol Chem. 2012 Oct 26; 287(44):36837-44. PMID: 22989877; PMCID: PMC3481286.
    46. Rossi A, Ratelade J, Papadopoulos MC, Bennett JL, Verkman AS. Neuromyelitis optica IgG does not alter aquaporin-4 water permeability, plasma membrane M1/M23 isoform content, or supramolecular assembly. Glia. 2012 Dec; 60(12):2027-39. PMID: 22987455; PMCID: PMC3586219.
    47. Arellano B, Hussain R, Zacharias T, Yoon J, David C, Zein S, Steinman L, Forsthuber T, Greenberg BM, Lambracht-Washington D, Ritchie AM, Bennett JL, Stüve O. Human aquaporin 4281-300 is the immunodominant linear determinant in the context of HLA-DRB1*03:01: relevance for diagnosing and monitoring patients with neuromyelitis optica. Arch Neurol. 2012 Sep; 69(9):1125-31. PMID: 22751865.
      View in: PubMed
    48. Srivastava R, Aslam M, Kalluri SR, Schirmer L, Buck D, Tackenberg B, Rothhammer V, Chan A, Gold R, Berthele A, Bennett JL, Korn T, Hemmer B. Potassium channel KIR4.1 as an immune target in multiple sclerosis. N Engl J Med. 2012 Jul 12; 367(2):115-23. PMID: 22784115.
      View in: PubMed
    49. Owens GP, Bennett JL. Trigger, pathogen, or bystander: the complex nexus linking Epstein- Barr virus and multiple sclerosis. Mult Scler. 2012 Sep; 18(9):1204-8. PMID: 22685062.
      View in: PubMed
    50. Rossi A, Ratelade J, Papadopoulos MC, Bennett JL, Verkman AS. Consequences of NMO-IgG binding to aquaporin-4 in neuromyelitis optica. Proc Natl Acad Sci U S A. 2012 Jun 12; 109(24):E1511; author reply E1512. PMID: 22589299; PMCID: PMC3386066.
    51. Bennett JL, Owens GP. Cerebrospinal fluid proteomics: a new window for understanding human demyelinating disorders? Ann Neurol. 2012 May; 71(5):587-8. PMID: 22522475.
      View in: PubMed
    52. Ratelade J, Zhang H, Saadoun S, Bennett JL, Papadopoulos MC, Verkman AS. Neuromyelitis optica IgG and natural killer cells produce NMO lesions in mice without myelin loss. Acta Neuropathol. 2012 Jun; 123(6):861-72. PMID: 22526022; PMCID: PMC3581313.
    53. Tradtrantip L, Zhang H, Anderson MO, Saadoun S, Phuan PW, Papadopoulos MC, Bennett JL, Verkman AS. Small-molecule inhibitors of NMO-IgG binding to aquaporin-4 reduce astrocyte cytotoxicity in neuromyelitis optica. FASEB J. 2012 May; 26(5):2197-208. PMID: 22319008; PMCID: PMC3336779.
    54. Tradtrantip L, Zhang H, Saadoun S, Phuan PW, Lam C, Papadopoulos MC, Bennett JL, Verkman AS. Anti-aquaporin-4 monoclonal antibody blocker therapy for neuromyelitis optica. Ann Neurol. 2012 Mar; 71(3):314-22. PMID: 22271321; PMCID: PMC3314396.
    55. Kumpe DA, Bennett JL, Seinfeld J, Pelak VS, Chawla A, Tierney M. Dural sinus stent placement for idiopathic intracranial hypertension. J Neurosurg. 2012 Mar; 116(3):538-48. PMID: 22149379.
      View in: PubMed
    56. Owens GP, Gilden D, Burgoon MP, Yu X, Bennett JL. Viruses and multiple sclerosis. Neuroscientist. 2011 Dec; 17(6):659-76. PMID: 22130640; PMCID: PMC3293404.
    57. Ratelade J, Bennett JL, Verkman AS. Evidence against cellular internalization in vivo of NMO-IgG, aquaporin-4, and excitatory amino acid transporter 2 in neuromyelitis optica. J Biol Chem. 2011 Dec 30; 286(52):45156-64. PMID: 22069320; PMCID: PMC3247969.
    58. Zhang H, Bennett JL, Verkman AS. Ex vivo spinal cord slice model of neuromyelitis optica reveals novel immunopathogenic mechanisms. Ann Neurol. 2011 Dec; 70(6):943-54. PMID: 22069219; PMCID: PMC3319401.
    59. Ratelade J, Bennett JL, Verkman AS. Intravenous neuromyelitis optica autoantibody in mice targets aquaporin-4 in peripheral organs and area postrema. PLoS One. 2011; 6(11):e27412. PMID: 22076159; PMCID: PMC3208637.
    60. Bucca BC, Klingensmith G, Bennett JL. Wolfram Syndrome: a rare optic neuropathy in youth with type 1 diabetes. Optom Vis Sci. 2011 Nov; 88(11):E1383-90. PMID: 21892113.
      View in: PubMed
    61. Brennan KM, Galban-Horcajo F, Rinaldi S, O'Leary CP, Goodyear CS, Kalna G, Arthur A, Elliot C, Barnett S, Linington C, Bennett JL, Owens GP, Willison HJ. Lipid arrays identify myelin-derived lipids and lipid complexes as prominent targets for oligoclonal band antibodies in multiple sclerosis. J Neuroimmunol. 2011 Sep 15; 238(1-2):87-95. PMID: 21872346; PMCID: PMC3400538.
    62. Teunissen CE, Tumani H, Bennett JL, Berven FS, Brundin L, Comabella M, Franciotta D, Federiksen JL, Fleming JO, Furlan R, Hintzen RQ, Hughes SG, Jimenez CR, Johnson MH, Killestein J, Krasulova E, Kuhle J, Magnone MC, Petzold A, Rajda C, Rejdak K, Schmidt HK, van Pesch V, Waubant E, Wolf C, Deisenhammer F, Giovannoni G, Hemmer B. Consensus Guidelines for CSF and Blood Biobanking for CNS Biomarker Studies. Mult Scler Int. 2011; 2011:246412. PMID: 22096631; PMCID: PMC3195993.
    63. Crane JM, Rossi A, Gupta T, Bennett JL, Verkman AS. Orthogonal array formation by human aquaporin-4: examination of neuromyelitis optica-associated aquaporin-4 polymorphisms. J Neuroimmunol. 2011 Jul; 236(1-2):93-8. PMID: 21621278; PMCID: PMC3582392.
    64. Yu X, Green M, Gilden D, Lam C, Bautista K, Bennett JL. Identification of peptide targets in neuromyelitis optica. J Neuroimmunol. 2011 Jul; 236(1-2):65-71. PMID: 21621279; PMCID: PMC3207235.
    65. Crane JM, Lam C, Rossi A, Gupta T, Bennett JL, Verkman AS. Binding affinity and specificity of neuromyelitis optica autoantibodies to aquaporin-4 M1/M23 isoforms and orthogonal arrays. J Biol Chem. 2011 May 06; 286(18):16516-24. PMID: 21454592; PMCID: PMC3091256.
    66. Weintraub JA, Bennett J, Gaspar LE. Successful treatment of radiation-induced optic neuropathy. Pract Radiat Oncol. 2011 Jan-Mar; 1(1):40-4. PMID: 24673869.
      View in: PubMed
    67. Yu X, Gilden D, Schambers L, Barmina O, Burgoon M, Bennett J, Owens G. Peptide reactivity between multiple sclerosis (MS) CSF IgG and recombinant antibodies generated from clonally expanded plasma cells in MS CSF. J Neuroimmunol. 2011 Apr; 233(1-2):192-203. PMID: 21176973; PMCID: PMC3277395.
    68. Gordon LK, Bennett JL. Preserving and restoring optic nerve function. J Neuroophthalmol. 2010 Dec; 30(4):303-4. PMID: 21107120.
      View in: PubMed
    69. Bennett JL, Miravalle AA. Recent advances in the treatment of multiple sclerosis. J Exp Pharmacol. 2010; 2:155-61. PMID: 27186101; PMCID: PMC4863296.
    70. Kalluri SR, Illes Z, Srivastava R, Cree B, Menge T, Bennett JL, Berthele A, Hemmer B. Quantification and functional characterization of antibodies to native aquaporin 4 in neuromyelitis optica. Arch Neurol. 2010 Oct; 67(10):1201-8. PMID: 20937947.
      View in: PubMed
    71. Warnke C, Menge T, Hartung HP, Racke MK, Cravens PD, Bennett JL, Frohman EM, Greenberg BM, Zamvil SS, Gold R, Hemmer B, Kieseier BC, Stüve O. Natalizumab and progressive multifocal leukoencephalopathy: what are the causal factors and can it be avoided? Arch Neurol. 2010 Aug; 67(8):923-30. PMID: 20697042; PMCID: PMC4157908.
    72. Crane JM, Bennett JL, Verkman AS. Live cell analysis of aquaporin-4 m1/m23 interactions and regulated orthogonal array assembly in glial cells. J Biol Chem. 2009 Dec 18; 284(51):35850-60. PMID: 19843522; PMCID: PMC2791014.
    73. Bennett JL, Lam C, Kalluri SR, Saikali P, Bautista K, Dupree C, Glogowska M, Case D, Antel JP, Owens GP, Gilden D, Nessler S, Stadelmann C, Hemmer B. Intrathecal pathogenic anti-aquaporin-4 antibodies in early neuromyelitis optica. Ann Neurol. 2009 Nov; 66(5):617-29. PMID: 19938104; PMCID: PMC3180961.
    74. Awad A, Hemmer B, Hartung HP, Kieseier B, Bennett JL, Stuve O. Analyses of cerebrospinal fluid in the diagnosis and monitoring of multiple sclerosis. J Neuroimmunol. 2010 Feb 26; 219(1-2):1-7. PMID: 19782408.
      View in: PubMed
    75. Cameron EM, Spencer S, Lazarini J, Harp CT, Ward ES, Burgoon M, Owens GP, Racke MK, Bennett JL, Frohman EM, Monson NL. Potential of a unique antibody gene signature to predict conversion to clinically definite multiple sclerosis. J Neuroimmunol. 2009 Aug 18; 213(1-2):123-30. PMID: 19631394; PMCID: PMC2785005.
    76. Owens GP, Bennett JL, Lassmann H, O'Connor KC, Ritchie AM, Shearer A, Lam C, Yu X, Birlea M, DuPree C, Williamson RA, Hafler DA, Burgoon MP, Gilden D. Antibodies produced by clonally expanded plasma cells in multiple sclerosis cerebrospinal fluid. Ann Neurol. 2009 Jun; 65(6):639-49. PMID: 19557869; PMCID: PMC2843543.
    77. Bennett JL, Stüve O. Update on inflammation, neurodegeneration, and immunoregulation in multiple sclerosis: therapeutic implications. Clin Neuropharmacol. 2009 May-Jun; 32(3):121-32. PMID: 19483479.
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    78. Burgoon MP, Cohrs RJ, Bennett JL, Anderson SW, Ritchie AM, Cepok S, Hemmer B, Gilden D, Owens GP. Varicella zoster virus is not a disease-relevant antigen in multiple sclerosis. Ann Neurol. 2009 Apr; 65(4):474-9. PMID: 19399839; PMCID: PMC2844106.
    79. Athappilly G, Pelak VS, Mandava N, Bennett JL. Ischemic optic neuropathy. Neurol Res. 2008 Oct; 30(8):794-800. PMID: 18826805.
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    80. Bennett JL, Haubold K, Ritchie AM, Edwards SJ, Burgoon M, Shearer AJ, Gilden DH, Owens GP. CSF IgG heavy-chain bias in patients at the time of a clinically isolated syndrome. J Neuroimmunol. 2008 Aug 13; 199(1-2):126-32. PMID: 18547652; PMCID: PMC2572301.
    81. Stüve O, Bennett JL, Hemmer B, Wiendl H, Racke MK, Bar-Or A, Hu W, Zivadinov R, Weber MS, Zamvil SS, Pacheco MF, Menge T, Hartung HP, Kieseier BC, Frohman EM. Pharmacological treatment of early multiple sclerosis. Drugs. 2008; 68(1):73-83. PMID: 18081373.
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    82. Winges KM, Gilden DH, Bennett JL, Yu X, Ritchie AM, Owens GP. Analysis of multiple sclerosis cerebrospinal fluid reveals a continuum of clonally related antibody-secreting cells that are predominantly plasma blasts. J Neuroimmunol. 2007 Dec; 192(1-2):226-34. PMID: 17997491.
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    83. Owens GP, Winges KM, Ritchie AM, Edwards S, Burgoon MP, Lehnhoff L, Nielsen K, Corboy J, Gilden DH, Bennett JL. VH4 gene segments dominate the intrathecal humoral immune response in multiple sclerosis. J Immunol. 2007 Nov 01; 179(9):6343-51. PMID: 17947712.
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    84. Bennett JL, Thomas S, Olson JL, Mandava N. Treatment of nonarteritic anterior ischemic optic neuropathy with intravitreal bevacizumab. J Neuroophthalmol. 2007 Sep; 27(3):238-40. PMID: 17895825.
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    85. Olson JL, Bennett J, Mandava N. Cerebellar and retinal vascular lesions in a postpartum patient. Am Fam Physician. 2007 Feb 01; 75(3):393-4. PMID: 17304873.
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    86. Stüve O, Bennett JL. Pharmacological properties, toxicology and scientific rationale for the use of natalizumab (Tysabri) in inflammatory diseases. CNS Drug Rev. 2007; 13(1):79-95. PMID: 17461891.
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    87. Kaur P, Bennett JL. Optic neuritis and the neuro-ophthalmology of multiple sclerosis. Int Rev Neurobiol. 2007; 79:633-63. PMID: 17531862.
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    88. Owens GP, Shearer AJ, Yu X, Ritchie AM, Keays KM, Bennett JL, Gilden DH, Burgoon MP. Screening random peptide libraries with subacute sclerosing panencephalitis brain-derived recombinant antibodies identifies multiple epitopes in the C-terminal region of the measles virus nucleocapsid protein. J Virol. 2006 Dec; 80(24):12121-30. PMID: 17130301; PMCID: PMC1676253.
    89. Simon JH, Zhang S, Laidlaw DH, Miller DE, Brown M, Corboy J, Bennett J. Identification of fibers at risk for degeneration by diffusion tractography in patients at high risk for MS after a clinically isolated syndrome. J Magn Reson Imaging. 2006 Nov; 24(5):983-8. PMID: 17024655.
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    90. Bennett JL. Natalizumab and progressive multifocal leukoencephalopathy: migrating towards safe adhesion molecule therapy in multiple sclerosis. Neurol Res. 2006 Apr; 28(3):291-8. PMID: 16687056.
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    91. Owens GP, Bennett JL, Gilden DH, Burgoon MP. The B cell response in multiple sclerosis. Neurol Res. 2006 Apr; 28(3):236-44. PMID: 16687047.
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    92. Oliver SC, Bennett JL. Genetic disorders and the optic nerve: a clinical survey. Ophthalmol Clin North Am. 2004 Sep; 17(3):435-45, vii. PMID: 15337198.
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    93. Haubold K, Owens GP, Kaur P, Ritchie AM, Gilden DH, Bennett JL. B-lymphocyte and plasma cell clonal expansion in monosymptomatic optic neuritis cerebrospinal fluid. Ann Neurol. 2004 Jul; 56(1):97-107. PMID: 15236406.
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    94. Chou KL, Galetta SL, Liu GT, Volpe NJ, Bennett JL, Asbury AK, Balcer LJ. Acute ocular motor mononeuropathies: prospective study of the roles of neuroimaging and clinical assessment. J Neurol Sci. 2004 Apr 15; 219(1-2):35-9. PMID: 15050435.
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    95. Gregory DG, Pelak VS, Bennett JL. Diffusion-weighted magnetic resonance imaging and the evaluation of cortical blindness in preeclampsia. Surv Ophthalmol. 2003 Nov-Dec; 48(6):647-50. PMID: 14609710.
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    96. Bennett JL. Developmental neurogenetics and neuro-ophthalmology. J Neuroophthalmol. 2002 Dec; 22(4):286-96. PMID: 12464733.
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    97. Costakos DM, Bennett JL. Dural Fistulas. Curr Treat Options Neurol. 2001 Jul; 3(4):377-382. PMID: 11389807.
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