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Tin Tin Su

TitleProfessor
InstitutionUniversity of Colorado Boulder
DepartmentBiology-MCD Instruction
Phone303/735-3245
ORCID ORCID Icon0000-0003-0139-4390 Additional info
    Other Positions
    TitleChair
    InstitutionUniversity of Colorado Boulder
    DepartmentBiology-MCD Instruction


    Collapse Research 
    Collapse research activities and funding
    F32GM015032     (SU, TIN TIN)Jan 31, 1993
    NIH/NIGMS
    TRANSCRIPTIONAL REGULATION OF STRING EXPRESSION
    Role: Principal Investigator

    R01GM066441     (SU, TIN TIN)May 1, 2002 - Apr 30, 2008
    NIH/NIGMS
    Cell Cycle Regulation by Checkpoints in Drosophila
    Role: Principal Investigator

    R21GM073973     (SU, TIN TIN)Feb 1, 2006 - Jan 31, 2008
    NIH/NIGMS
    Cell Growth and Radiation Survival in Drosophila
    Role: Principal Investigator

    R21DE017494     (SU, TIN TIN)May 1, 2007 - Apr 30, 2010
    NIH/NIDCR
    An in vivo Screen for Radiation Sensitizers
    Role: Principal Investigator

    R01GM087276     (SU, TIN TIN)Sep 30, 2009 - Aug 31, 2014
    NIH/NIGMS
    Regulation of Radiation Induced Cell Death in Drosophila
    Role: Principal Investigator

    R01GM106317     (SU, TIN TIN)Aug 1, 2014 - Jun 30, 2018
    NIH/NIGMS
    Consequences of Cell Death in Drosophila
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Stickel SA, Gomes NP, Frederick B, Raben D, Su TT. Bouvardin is a Radiation Modulator with a Novel Mechanism of Action. Radiat Res. 2015 Oct; 184(4):392-403. PMID: 26414509.
      View in: PubMed
    2. Xing Y, Su TT, Ruohola-Baker H. Tie-mediated signal from apoptotic cells protects stem cells in Drosophila melanogaster. Nat Commun. 2015 May 11; 6:7058. PMID: 25959206.
      View in: PubMed
    3. Su TT. Non-autonomous consequences of cell death and other perks of being metazoan. AIMS Genet. 2015; 2(1):54-69. PMID: 26069889.
      View in: PubMed
    4. Stickel S, Gomes N, Su TT. The Role of Translational Regulation in Survival after Radiation Damage; an Opportunity for Proteomics Analysis. Proteomes. 2014 Jun; 2(2):272-290. PMID: 26269784.
      View in: PubMed
    5. Bilak A, Uyetake L, Su TT. Dying cells protect survivors from radiation-induced cell death in Drosophila. PLoS Genet. 2014 Mar; 10(3):e1004220. PMID: 24675716.
      View in: PubMed
    6. Stickel S, Su TT. Oncogenic mutations produce similar phenotypes in Drosophila tissues of diverse origins. Biol Open. 2014 Mar 15; 3(3):201-9. PMID: 24570398.
      View in: PubMed
    7. van Bergeijk P, Heimiller J, Uyetake L, Su TT. Genome-wide expression analysis identifies a modulator of ionizing radiation-induced p53-independent apoptosis in Drosophila melanogaster. PLoS One. 2012; 7(5):e36539. PMID: 22666323.
      View in: PubMed
    8. Gladstone M, Frederick B, Zheng D, Edwards A, Yoon P, Stickel S, DeLaney T, Chan DC, Raben D, Su TT. A translation inhibitor identified in a Drosophila screen enhances the effect of ionizing radiation and taxol in mammalian models of cancer. Dis Model Mech. 2012 May; 5(3):342-50. PMID: 22344740.
      View in: PubMed
    9. Gladstone M, Su TT. Radiation responses and resistance. Int Rev Cell Mol Biol. 2012; 299:235-53. PMID: 22959305.
      View in: PubMed
    10. Gladstone M, Su TT. Chemical genetics and drug screening in Drosophila cancer models. J Genet Genomics. 2011 Oct 20; 38(10):497-504. PMID: 22035870.
      View in: PubMed
    11. Su TT. Safeguarding genetic information in Drosophila. Chromosoma. 2011 Dec; 120(6):547-55. PMID: 21927823.
      View in: PubMed
    12. Edwards A, Gladstone M, Yoon P, Raben D, Frederick B, Su TT. Combinatorial effect of maytansinol and radiation in Drosophila and human cancer cells. Dis Model Mech. 2011 Jul; 4(4):496-503. PMID: 21504911.
      View in: PubMed
    13. Gladstone M, Su TT. Screening for radiation sensitizers of Drosophila checkpoint mutants. Methods Mol Biol. 2011; 782:105-17. PMID: 21870288.
      View in: PubMed
    14. Smith MK, Trujillo C, Su TT. The benefits of using clickers in small-enrollment seminar-style biology courses. CBE Life Sci Educ. 2011; 10(1):14-7. PMID: 21364096.
      View in: PubMed
    15. Su TT. Heterochromatin replication: better late than ever. Curr Biol. 2010 Dec 07; 20(23):R1018-20. PMID: 21145016.
      View in: PubMed
    16. Wichmann A, Uyetake L, Su TT. E2F1 and E2F2 have opposite effects on radiation-induced p53-independent apoptosis in Drosophila. Dev Biol. 2010 Oct 01; 346(1):80-9. PMID: 20659447.
      View in: PubMed
    17. Su TT. The effect of a DNA damaging agent on embryonic cell cycles of the cnidarian Hydractinia echinata. PLoS One. 2010 Jul 23; 5(7):e11760. PMID: 20668699.
      View in: PubMed
    18. Garcia K, Stumpff J, Duncan T, Su TT. Tyrosines in the kinesin-5 head domain are necessary for phosphorylation by Wee1 and for mitotic spindle integrity. Curr Biol. 2009 Oct 13; 19(19):1670-6. PMID: 19800237.
      View in: PubMed
    19. Bilak A, Su TT. Regulation of Drosophila melanogaster pro-apoptotic gene hid. Apoptosis. 2009 Aug; 14(8):943-9. PMID: 19554451.
      View in: PubMed
    20. Smith MK, Wood WB, Adams WK, Wieman C, Knight JK, Guild N, Su TT. Why peer discussion improves student performance on in-class concept questions. Science. 2009 Jan 02; 323(5910):122-4. PMID: 19119232.
      View in: PubMed
    21. Yi X, Lemstra W, Vos MJ, Shang Y, Kampinga HH, Su TT, Sibon OC. A long-term flow cytometry assay to analyze the role of specific genes of Drosophila melanogaster S2 cells in surviving genotoxic stress. Cytometry A. 2008 Jul; 73(7):637-42. PMID: 18496848.
      View in: PubMed
    22. Garcia K, Su TT. Cell cycle regulation. Fly (Austin). 2008 May-Jun; 2(3):133-7. PMID: 18820450.
      View in: PubMed
    23. Jaklevic B, Uyetake L, Wichmann A, Bilak A, English CN, Su TT. Modulation of ionizing radiation-induced apoptosis by bantam microRNA in Drosophila. Dev Biol. 2008 Aug 01; 320(1):122-30. PMID: 18550049.
      View in: PubMed
    24. Garcia K, Wichmann A, Su TT. Cell cycle regulation. Fly (Austin). 2007 Mar-Apr; 1(2):125-31. PMID: 19378458.
      View in: PubMed
    25. Garcia K, Duncan T, Su TT. Analysis of the cell division cycle in Drosophila. Methods. 2007 Feb; 41(2):198-205. PMID: 17189862.
      View in: PubMed
    26. LaRocque JR, Jaklevic B, Su TT, Sekelsky J. Drosophila ATR in double-strand break repair. Genetics. 2007 Mar; 175(3):1023-33. PMID: 17194776.
      View in: PubMed
    27. Wichmann A, Jaklevic B, Su TT. Ionizing radiation induces caspase-dependent but Chk2- and p53-independent cell death in Drosophila melanogaster. Proc Natl Acad Sci U S A. 2006 Jun 27; 103(26):9952-7. PMID: 16785441.
      View in: PubMed
    28. Su TT. Cellular responses to DNA damage: one signal, multiple choices. Annu Rev Genet. 2006; 40:187-208. PMID: 16805666.
      View in: PubMed
    29. Stumpff J, Kellogg DR, Krohne KA, Su TT. Drosophila Wee1 interacts with members of the gammaTURC and is required for proper mitotic-spindle morphogenesis and positioning. Curr Biol. 2005 Sep 06; 15(17):1525-34. PMID: 16139207.
      View in: PubMed
    30. Purdy A, Uyetake L, Cordeiro MG, Su TT. Regulation of mitosis in response to damaged or incompletely replicated DNA require different levels of Grapes (Drosophila Chk1). J Cell Sci. 2005 Aug 01; 118(Pt 15):3305-15. PMID: 16079276.
      View in: PubMed
    31. de Vries HI, Uyetake L, Lemstra W, Brunsting JF, Su TT, Kampinga HH, Sibon OC. Grp/DChk1 is required for G2-M checkpoint activation in Drosophila S2 cells, whereas Dmnk/DChk2 is dispensable. J Cell Sci. 2005 May 01; 118(Pt 9):1833-42. PMID: 15860729.
      View in: PubMed
    32. Stumpff J, Duncan T, Homola E, Campbell SD, Su TT. Drosophila Wee1 kinase regulates Cdk1 and mitotic entry during embryogenesis. Curr Biol. 2004 Dec 14; 14(23):2143-8. PMID: 15589158.
      View in: PubMed
    33. Purdy A, Su TT. Telomeres: not all breaks are equal. Curr Biol. 2004 Aug 10; 14(15):R613-4. PMID: 15296775.
      View in: PubMed
    34. Duncan T, Su TT. Embryogenesis: coordinating cell division with gastrulation. Curr Biol. 2004 Apr 20; 14(8):R305-7. PMID: 15084299.
      View in: PubMed
    35. Su TT, Stumpff J. Promiscuity rules? The dispensability of cyclin E and Cdk2. Sci STKE. 2004 Mar 09; 2004(224):pe11. PMID: 15026579.
      View in: PubMed
    36. Jaklevic BR, Su TT. Relative contribution of DNA repair, cell cycle checkpoints, and cell death to survival after DNA damage in Drosophila larvae. Curr Biol. 2004 Jan 06; 14(1):23-32. PMID: 14711410.
      View in: PubMed
    37. O'Farrell PH, Stumpff J, Su TT. Embryonic cleavage cycles: how is a mouse like a fly? Curr Biol. 2004 Jan 06; 14(1):R35-45. PMID: 14711435.
      View in: PubMed
    38. Jaklevic B, Purdy A, Su TT. Control of mitotic entry after DNA damage in Drosophila. Methods Mol Biol. 2004; 280:245-56. PMID: 15187258.
      View in: PubMed
    39. Jaklevic B, Su TT. Cell turnover: flexible coupling meets the needs of development. Curr Biol. 2003 Oct 14; 13(20):R805-7. PMID: 14561421.
      View in: PubMed
    40. De Felice B, Wilson RR, Mondola P, Matrone G, Damiano S, Garbi C, Nezi L, Su TT. Characterization of DIP1, a novel nuclear protein in Drosophila melanogaster. Biochem Biophys Res Commun. 2003 Jul 25; 307(2):224-8. PMID: 12859943.
      View in: PubMed
    41. Laurençon A, Purdy A, Sekelsky J, Hawley RS, Su TT. Phenotypic analysis of separation-of-function alleles of MEI-41, Drosophila ATM/ATR. Genetics. 2003 Jun; 164(2):589-601. PMID: 12807779.
      View in: PubMed
    42. Garner M, van Kreeveld S, Su TT. mei-41 and bub1 block mitosis at two distinct steps in response to incomplete DNA replication in Drosophila embryos. Curr Biol. 2001 Oct 16; 11(20):1595-9. PMID: 11676920.
      View in: PubMed
    43. Su TT, Parry DH, Donahoe B, Chien CT, O'Farrell PH, Purdy A. Cell cycle roles for two 14-3-3 proteins during Drosophila development. J Cell Sci. 2001 Oct; 114(Pt 19):3445-54. PMID: 11682604.
      View in: PubMed
    44. Tin Su T. Cell cycle: how, when and why cells get rid of cyclin A. Curr Biol. 2001 Jun 26; 11(12):R467-9. PMID: 11448787.
      View in: PubMed
    45. Su TT, Jaklevic B. DNA damage leads to a Cyclin A-dependent delay in metaphase-anaphase transition in the Drosophila gastrula. Curr Biol. 2001 Jan 09; 11(1):8-17. PMID: 11166174.
      View in: PubMed
    46. Su TT, Walker J, Stumpff J. Activating the DNA damage checkpoint in a developmental context. Curr Biol. 2000 Feb 10; 10(3):119-26. PMID: 10679321.
      View in: PubMed
    47. Su TT. The regulation of cell growth and proliferation during organogenesis. In Vivo. 2000 Jan-Feb; 14(1):141-8. PMID: 10757071.
      View in: PubMed
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