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David D Ivy

TitleProfessor
InstitutionUniversity of Colorado Denver - Anschutz Medical Campus
DepartmentSOM-PEDS
Phone720/777-8229

    Collapse Research 
    Collapse research activities and funding
    K08HL003823     (IVY, DAVID D)Sep 15, 1999 - Aug 31, 2003
    NIH/NHLBI
    ROLE OF ENDOTHELIN IN PERINATAL PULMONARY VASOREGULATION
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Krishnan U, Feinstein JA, Adatia I, Austin ED, Mullen MP, Hopper RK, Hanna B, Romer L, Keller RL, Fineman J, Steinhorn R, Kinsella JP, Ivy DD, Rosenzweig EB, Raj U, Humpl T, Abman SH. Evaluation and Management of Pulmonary Hypertension in Children with Bronchopulmonary Dysplasia. J Pediatr. 2017 Jun 20. PMID: 28645441.
      View in: PubMed
    2. Parker DK, Shen S, Zheng J, Ivy DD, Crotwell DN, Hotz JC, DiBlasi RM. Inhaled Treprostinil Drug Delivery During Mechanical Ventilation and Spontaneous Breathing Using Two Different Nebulizers. Pediatr Crit Care Med. 2017 Jun; 18(6):e253-e260. PMID: 28441181.
      View in: PubMed
    3. Hauck A, Guo R, Ivy DD, Younoszai A. Tricuspid annular plane systolic excursion is preserved in young patients with pulmonary hypertension except when associated with repaired congenital heart disease. Eur Heart J Cardiovasc Imaging. 2017 Apr 01; 18(4):459-466. PMID: 27099276.
      View in: PubMed
    4. Schäfer M, Ivy DD, Barker AJ, Kheyfets V, Shandas R, Abman SH, Hunter KS, Truong U. Characterization of CMR-derived haemodynamic data in children with pulmonary arterial hypertension. Eur Heart J Cardiovasc Imaging. 2017 Apr 01; 18(4):424-431. PMID: 27444679.
      View in: PubMed
    5. Colvin KL, Ivy DD, Yeager ME. Altered Peripheral Blood Myeloid Cell Subpopulations in Children With Down Syndrome and Pulmonary Hypertension. J Pediatr Hematol Oncol. 2017 Mar; 39(2):158-159. PMID: 28060127.
      View in: PubMed
    6. Schäfer M, Ivy DD, Abman SH, Barker AJ, Browne LP, Fonseca B, Kheyfets V, Hunter KS, Truong U. Apparent Aortic Stiffness in Children With Pulmonary Arterial Hypertension: Existence of Vascular Interdependency? Circ Cardiovasc Imaging. 2017 Feb; 10(2). PMID: 28193613.
      View in: PubMed
    7. Zijlstra WM, Elmasry O, Pepplinkhuizen S, Ivy DD, Bonnet D, Luijendijk P, Lévy M, Gavilan JL, Torrent-Vernetta A, Mendoza A, Del Cerro MJ, Moledina S, Berger RM. Pulmonary arterial hypertension in children after neonatal arterial switch operation. Heart. 2017 Aug; 103(16):1244-1249. PMID: 28115472.
      View in: PubMed
    8. Yang J, Nies MK, Fu Z, Damico R, Korley FK, Hassoun PM, Ivy DD, Austin ED, Everett AD. Hepatoma-derived Growth Factor Predicts Disease Severity and Survival in Pulmonary Arterial Hypertension. Am J Respir Crit Care Med. 2016 Nov 15; 194(10):1264-1272. PMID: 27254543.
      View in: PubMed
    9. Clopton RG, Friesen R, Partrick D, Wilson N, Jaggers J, Ivy DD, Schwartz LI, Ing RJ. The Anesthetic Challenges of Lung Biopsy-Associated Intrathoracic Hemorrhage in a Child With Suprasystemic Pulmonary Hypertension. Semin Cardiothorac Vasc Anesth. 2017 Jun; 21(2):172-177. PMID: 27815350.
      View in: PubMed
    10. Takatsuki S, Nakayama T, Ikehara S, Matsuura H, Ivy DD, Saji T. Pulmonary Arterial Capacitance Index Is a Strong Predictor for Adverse Outcome in Children with Idiopathic and Heritable Pulmonary Arterial Hypertension. J Pediatr. 2017 Jan; 180:75-79.e2. PMID: 27810156.
      View in: PubMed
    11. Abman SH, Ivy DD, Archer SL, Wilson K. Executive Summary of the American Heart Association and American Thoracic Society Joint Guidelines for Pediatric Pulmonary Hypertension. Am J Respir Crit Care Med. 2016 Oct 01; 194(7):898-906. PMID: 27689707.
      View in: PubMed
    12. Burkett DA, Slorach C, Patel SS, Redington AN, Ivy DD, Mertens L, Younoszai AK, Friedberg MK. Impact of Pulmonary Hemodynamics and Ventricular Interdependence on Left Ventricular Diastolic Function in Children With Pulmonary Hypertension. Circ Cardiovasc Imaging. 2016 Sep; 9(9). PMID: 27581953; PMCID: PMC5012318 [Available on 09/01/17].
      View in: PubMed, PubMed Central
    13. Zijlstra WM, Douwes JM, Ploegstra MJ, Krishnan U, Roofthooft MT, Hillege HL, Ivy DD, Rosenzweig EB, Berger RM. Clinical classification in pediatric pulmonary arterial hypertension associated with congenital heart disease. Pulm Circ. 2016 Sep; 6(3):302-12. PMID: 27683607.
      View in: PubMed
    14. Berger RM, Haworth SG, Bonnet D, Dulac Y, Fraisse A, Galiè N, Ivy DD, Jaïs X, Miera O, Rosenzweig EB, Efficace M, Kusic-Pajic A, Beghetti M. Corrigendum to "FUTURE-2: Results from an open-label, long-term safety and tolerability extension study using the pediatric FormUlation of bosenTan in pUlmonary arterial hypeRtEnsion" [Int. J. Cardiol. 202 (2016) 52-58]. Int J Cardiol. 2016 Nov 15; 223:1072-1073. PMID: 27623401.
      View in: PubMed
    15. Douwes JM, Humpl T, Bonnet D, Beghetti M, Ivy DD, Berger RM. Acute Vasodilator Response in Pediatric Pulmonary Arterial Hypertension: Current Clinical Practice From the TOPP Registry. J Am Coll Cardiol. 2016 Mar 22; 67(11):1312-23. PMID: 26988953.
      View in: PubMed
    16. Ploegstra MJ, Ivy DD, Wheeler JG, Brand M, Beghetti M, Rosenzweig EB, Humpl T, Iriart X, Rouzic EM, Bonnet D, Berger RM. Growth in children with pulmonary arterial hypertension: a longitudinal retrospective multiregistry study. Lancet Respir Med. 2016 Apr; 4(4):281-90. PMID: 26994897.
      View in: PubMed
    17. Jone PN, Patel SS, Cassidy C, Ivy DD. Three-dimensional Echocardiography of Right Ventricular Function Correlates with Severity of Pediatric Pulmonary Hypertension. Congenit Heart Dis. 2016 Dec; 11(6):562-569. PMID: 26899626.
      View in: PubMed
    18. Hopper RK, Abman SH, Ivy DD. Persistent Challenges in Pediatric Pulmonary Hypertension. Chest. 2016 Jul; 150(1):226-36. PMID: 26836930.
      View in: PubMed
    19. Kinsella JP, Steinhorn RH, Krishnan US, Feinstein JA, Adatia I, Austin ED, Rosenzweig EB, Everett AD, Fineman JR, Hanna BD, Hopper RK, Humpl T, Ivy DD, Keller RL, Mullen MP, Raj JU, Wessel DL, Abman SH. Recommendations for the Use of Inhaled Nitric Oxide Therapy in Premature Newborns with Severe Pulmonary Hypertension. J Pediatr. 2016 Mar; 170:312-4. PMID: 26703869.
      View in: PubMed
    20. Kheyfets VO, Dunning J, Truong U, Ivy DD, Hunter KA, Shandas R. Assessment of N-terminal prohormone B-type natriuretic peptide as a measure of vascular and ventricular function in pediatric pulmonary arterial hypertension. Pulm Circ. 2015 Dec; 5(4):658-66. PMID: 26697173; PMCID: PMC4671740.
      View in: PubMed, PubMed Central
    21. Friesen RH, Twite MD, Nichols CS, Cardwell KA, Pan Z, Darst JR, Wilson N, Fagan TE, Miyamoto SD, Ivy DD. Hemodynamic response to ketamine in children with pulmonary hypertension. Paediatr Anaesth. 2016 Jan; 26(1):102-8. PMID: 26564806.
      View in: PubMed
    22. Abman SH, Hansmann G, Archer SL, Ivy DD, Adatia I, Chung WK, Hanna BD, Rosenzweig EB, Raj JU, Cornfield D, Stenmark KR, Steinhorn R, Thébaud B, Fineman JR, Kuehne T, Feinstein JA, Friedberg MK, Earing M, Barst RJ, Keller RL, Kinsella JP, Mullen M, Deterding R, Kulik T, Mallory G, Humpl T, Wessel DL. Pediatric Pulmonary Hypertension: Guidelines From the American Heart Association and American Thoracic Society. Circulation. 2015 Nov 24; 132(21):2037-99. PMID: 26534956.
      View in: PubMed
    23. Beghetti M, Schulze-Neick I, Berger RM, Ivy DD, Bonnet D, Weintraub RG, Saji T, Yung D, Mallory GB, Geiger R, Berger JT, Barst RJ, Humpl T. Haemodynamic characterisation and heart catheterisation complications in children with pulmonary hypertension: Insights from the Global TOPP Registry (tracking outcomes and practice in paediatric pulmonary hypertension). Int J Cardiol. 2016 Jan 15; 203:325-30. PMID: 26583838.
      View in: PubMed
    24. Stewart L, MacLean EL, Ivy D, Woods V, Cohen E, Rodriguez K, McIntyre M, Mukherjee S, Call J, Kaminski J, Miklósi Á, Wrangham RW, Hare B. Citizen Science as a New Tool in Dog Cognition Research. PLoS One. 2015; 10(9):e0135176. PMID: 26376443; PMCID: PMC4574109.
      View in: PubMed, PubMed Central
    25. Di Maria MV, Burkett DA, Younoszai AK, Landeck BF, Mertens L, Ivy DD, Friedberg MK, Hunter KS. Echocardiographic estimation of right ventricular stroke work in children with pulmonary arterial hypertension: comparison with invasive measurements. J Am Soc Echocardiogr. 2015 Nov; 28(11):1350-7. PMID: 26299333.
      View in: PubMed
    26. Berger RM, Haworth SG, Bonnet D, Dulac Y, Fraisse A, Galiè N, Ivy DD, Jaïs X, Miera O, Rosenzweig EB, Efficace M, Kusic-Pajic A, Beghetti M. FUTURE-2: Results from an open-label, long-term safety and tolerability extension study using the pediatric FormUlation of bosenTan in pUlmonary arterial hypeRtEnsion. Int J Cardiol. 2016 Jan 01; 202:52-8. PMID: 26386921.
      View in: PubMed
    27. Burkett DA, Slorach C, Patel SS, Redington AN, Ivy DD, Mertens L, Younoszai AK, Friedberg MK. Left Ventricular Myocardial Function in Children With Pulmonary Hypertension: Relation to Right Ventricular Performance and Hemodynamics. Circ Cardiovasc Imaging. 2015 Aug; 8(8). PMID: 26259580; PMCID: PMC4535191.
      View in: PubMed, PubMed Central
    28. Abman SH, Ivy DD. Hospitalizations of Children With Pulmonary Hypertension: Implications for Improving Care. Pediatrics. 2015 Aug; 136(2):392-3. PMID: 26148953; PMCID: PMC4516950.
      View in: PubMed, PubMed Central
    29. Webber SA, Hsu DT, Ivy DD, Kulik TJ, Pahl E, Rosenthal DN, Morrow WR, Feinstein JA. Task Force 7: Pediatric Cardiology Fellowship Training in Pulmonary Hypertension, Advanced Heart Failure, and Transplantation. J Am Coll Cardiol. 2015 Aug 11; 66(6):732-9. PMID: 25777654.
      View in: PubMed
    30. Webber SA, Hsu DT, Ivy DD, Kulik TJ, Pahl E, Rosenthal DN, Morrow WR, Feinstein JA. Task Force 7: Pediatric Cardiology Fellowship Training in Pulmonary Hypertension, Advanced Heart Failure, and Transplantation. SPCTPD/ACC/AAP/AHA. Circulation. 2015 Aug 11; 132(6):e99-e106. PMID: 25769631.
      View in: PubMed
    31. Ross RD, Brook M, Feinstein JA, Koenig P, Lang P, Spicer R, Vincent JA, Lewis AB, Martin GR, Bartz PJ, Fischbach PS, Fulton DR, Matherne GP, Reinking B, Srivastava S, Printz B, Geva T, Shirali GS, Weinberg P, Wong PC, Armsby LB, Vincent RN, Foerster SR, Holzer RJ, Moore JW, Marshall AC, Latson L, Dubin AM, Walsh EP, Franklin W, Kanter RJ, Saul JP, Shah MJ, Van Hare GF, Feltes TF, Roth SJ, Almodovar MC, Andropoulos DB, Bohn DJ, Costello JM, Gajarski RJ, Mott AR, Stout K, Valente AM, Cook S, Gurvitz M, Saidi A, Webber SA, Hsu DT, Ivy DD, Kulik TJ, Pahl E, Rosenthal DN, Morrow R, Mahle WT, Murphy AM, Li JS, Law YM, Newburger JW, Daniels SR, Bernstein D, Marino BS. 2015 SPCTPD/ACC/AAP/AHA Training Guidelines for Pediatric Cardiology Fellowship Programs (Revision of the 2005 Training Guidelines for Pediatric Cardiology Fellowship Programs). J Am Coll Cardiol. 2015 Mar 13. PMID: 25777637.
      View in: PubMed
    32. Ivy DD, Abman SH. Gaining insights into pediatric pulmonary hypertensive disorders through patient registries. Am J Respir Crit Care Med. 2015 Jan 01; 191(1):2-4. PMID: 25551339.
      View in: PubMed
    33. Jone PN, Bremen C, DiMaria M, Campbell DN, Jaggers J, Younoszai A, Ivy DD. Three-dimensional echocardiography enhances diagnostic accuracy of supramitral ring. Echocardiography. 2015 Jun; 32(6):1048-50. PMID: 25496227.
      View in: PubMed
    34. Nies MK, Ivy DD, Everett AD. The untapped potential of proteomic analysis in pediatric pulmonary hypertension. Proteomics Clin Appl. 2014 Dec; 8(11-12):862-74. PMID: 25348110.
      View in: PubMed
    35. Jone PN, Ivy DD. Echocardiography in pediatric pulmonary hypertension. Front Pediatr. 2014; 2:124. PMID: 25429362; PMCID: PMC4228850.
      View in: PubMed, PubMed Central
    36. Di Maria MV, Younoszai AK, Mertens L, Landeck BF, Ivy DD, Hunter KS, Friedberg MK. RV stroke work in children with pulmonary arterial hypertension: estimation based on invasive haemodynamic assessment and correlation with outcomes. Heart. 2014 Sep; 100(17):1342-7. PMID: 24780910.
      View in: PubMed
    37. Zijlstra WM, Douwes JM, Rosenzweig EB, Schokker S, Krishnan U, Roofthooft MT, Miller-Reed K, Hillege HL, Ivy DD, Berger RM. Survival differences in pediatric pulmonary arterial hypertension: clues to a better understanding of outcome and optimal treatment strategies. J Am Coll Cardiol. 2014 May 27; 63(20):2159-69. PMID: 24681143.
      View in: PubMed
    38. Barst RJ, Beghetti M, Pulido T, Layton G, Konourina I, Zhang M, Ivy DD. STARTS-2: long-term survival with oral sildenafil monotherapy in treatment-naive pediatric pulmonary arterial hypertension. Circulation. 2014 May 13; 129(19):1914-23. PMID: 24637559.
      View in: PubMed
    39. Colvin KL, Dufva MJ, Delaney RP, Ivy DD, Stenmark KR, Yeager ME. Biomarkers for pediatric pulmonary arterial hypertension - a call to collaborate. Front Pediatr. 2014; 2:7. PMID: 24551834; PMCID: PMC3910125.
      View in: PubMed, PubMed Central
    40. Vorhies EE, Ivy DD. Drug treatment of pulmonary hypertension in children. Paediatr Drugs. 2014 Feb; 16(1):43-65. PMID: 24114695; PMCID: PMC3946901.
      View in: PubMed, PubMed Central
    41. Ivy DD, Abman SH, Barst RJ, Berger RM, Bonnet D, Fleming TR, Haworth SG, Raj JU, Rosenzweig EB, Schulze Neick I, Steinhorn RH, Beghetti M. Pediatric pulmonary hypertension. J Am Coll Cardiol. 2013 Dec 24; 62(25 Suppl):D117-26. PMID: 24355636.
      View in: PubMed
    42. Jone PN, Hinzman J, Wagner BD, Ivy DD, Younoszai A. Right ventricular to left ventricular diameter ratio at end-systole in evaluating outcomes in children with pulmonary hypertension. J Am Soc Echocardiogr. 2014 Feb; 27(2):172-8. PMID: 24325962; PMCID: PMC3922965.
      View in: PubMed, PubMed Central
    43. Wagner BD, Takatsuki S, Accurso FJ, Ivy DD. Evaluation of circulating proteins and hemodynamics towards predicting mortality in children with pulmonary arterial hypertension. PLoS One. 2013; 8(11):e80235. PMID: 24278261; PMCID: PMC3835871.
      View in: PubMed, PubMed Central
    44. Colvin KL, Cripe PJ, Ivy DD, Stenmark KR, Yeager ME. Bronchus-associated lymphoid tissue in pulmonary hypertension produces pathologic autoantibodies. Am J Respir Crit Care Med. 2013 Nov 01; 188(9):1126-36. PMID: 24093638; PMCID: PMC3863738.
      View in: PubMed, PubMed Central
    45. Rausch CM, Taylor AL, Ross H, Sillau S, Ivy DD. Ventilatory efficiency slope correlates with functional capacity, outcomes, and disease severity in pediatric patients with pulmonary hypertension. Int J Cardiol. 2013 Nov 30; 169(6):445-8. PMID: 24144928; PMCID: PMC3909671.
      View in: PubMed, PubMed Central
    46. Barst RJ, Ivy DD, Foreman AJ, McGoon MD, Rosenzweig EB. Four- and seven-year outcomes of patients with congenital heart disease-associated pulmonary arterial hypertension (from the REVEAL Registry). Am J Cardiol. 2014 Jan 01; 113(1):147-55. PMID: 24176071.
      View in: PubMed
    47. Truong U, Fonseca B, Dunning J, Burgett S, Lanning C, Ivy DD, Shandas R, Hunter K, Barker AJ. Wall shear stress measured by phase contrast cardiovascular magnetic resonance in children and adolescents with pulmonary arterial hypertension. J Cardiovasc Magn Reson. 2013 Sep 13; 15:81. PMID: 24034144; PMCID: PMC3848825.
      View in: PubMed, PubMed Central
    48. Takatsuki S, Ivy DD. Current challenges in pediatric pulmonary hypertension. Semin Respir Crit Care Med. 2013 Oct; 34(5):627-44. PMID: 24037630; PMCID: PMC3909673.
      View in: PubMed, PubMed Central
    49. Friesen RH, Nichols CS, Twite MD, Cardwell KA, Pan Z, Pietra B, Miyamoto SD, Auerbach SR, Darst JR, Ivy DD. The hemodynamic response to dexmedetomidine loading dose in children with and without pulmonary hypertension. Anesth Analg. 2013 Oct; 117(4):953-9. PMID: 23960035; PMCID: PMC3830564.
      View in: PubMed, PubMed Central
    50. Maxey DM, Ivy DD, Ogawa MT, Feinstein JA. Food and Drug Administration (FDA) postmarket reported side effects and adverse events associated with pulmonary hypertension therapy in pediatric patients. Pediatr Cardiol. 2013 Oct; 34(7):1628-36. PMID: 23532466; PMCID: PMC3783558.
      View in: PubMed, PubMed Central
    51. Siehr SL, Ivy DD, Miller-Reed K, Ogawa M, Rosenthal DN, Feinstein JA. Children with pulmonary arterial hypertension and prostanoid therapy: long-term hemodynamics. J Heart Lung Transplant. 2013 May; 32(5):546-52. PMID: 23453572; PMCID: PMC3760159.
      View in: PubMed, PubMed Central
    52. Zhou Z, Malhotra SP, Yu X, Rutledge J, Rebeyka IM, Ross DB, Rausch C, Gu H, McCrindle B, Lacour-Gayet F, Ivy D, Li J. Moderate altitude is not associated with adverse postoperative outcomes for patients undergoing bidirectional cavopulmonary anastomosis and Fontan operation: a comparative study among Denver, Edmonton, and Toronto. J Thorac Cardiovasc Surg. 2013 Nov; 146(5):1165-71. PMID: 23353110; PMCID: PMC3800264.
      View in: PubMed, PubMed Central
    53. Adatia I, Haworth SG, Wegner M, Barst RJ, Ivy D, Stenmark KR, Karkowsky A, Rosenzweig E, Aguilar C. Clinical trials in neonates and children: Report of the pulmonary hypertension academic research consortium pediatric advisory committee. Pulm Circ. 2013 Jan; 3(1):252-66. PMID: 23662203; PMCID: PMC3641736.
      View in: PubMed, PubMed Central
    54. Grieve AP, Chow SC, Curram J, Dawe S, Harnisch LO, Henig NR, Hung HM, Ivy DD, Kawut SM, Rahbar MH, Xiao S, Wilkins MR. Advancing clinical trial design in pulmonary hypertension. Pulm Circ. 2013 Jan; 3(1):217-25. PMID: 23662200; PMCID: PMC3641733.
      View in: PubMed, PubMed Central
    55. Duncan M, Wagner BD, Murray K, Allen J, Colvin K, Accurso FJ, Ivy DD. Circulating cytokines and growth factors in pediatric pulmonary hypertension. Mediators Inflamm. 2012; 2012:143428. PMID: 23316102; PMCID: PMC3536060.
      View in: PubMed, PubMed Central
    56. Takatsuki S, Parker DK, Doran AK, Friesen RH, Ivy DD. Acute pulmonary vasodilator testing with inhaled treprostinil in children with pulmonary arterial hypertension. Pediatr Cardiol. 2013 Apr; 34(4):1006-12. PMID: 23184020; PMCID: PMC3608847.
      View in: PubMed, PubMed Central
    57. Krishnan U, Takatsuki S, Ivy DD, Kerstein J, Calderbank M, Coleman E, Rosenzweig EB. Effectiveness and safety of inhaled treprostinil for the treatment of pulmonary arterial hypertension in children. Am J Cardiol. 2012 Dec 01; 110(11):1704-9. PMID: 22917554; PMCID: PMC3508003.
      View in: PubMed, PubMed Central
    58. Takatsuki S, Nakayama T, Jone PN, Wagner BD, Naoi K, Ivy DD, Saji T. Tissue Doppler imaging predicts adverse outcome in children with idiopathic pulmonary arterial hypertension. J Pediatr. 2012 Dec; 161(6):1126-31. PMID: 22748515; PMCID: PMC3508005.
      View in: PubMed, PubMed Central
    59. Yeager ME, Colvin KL, Everett AD, Stenmark KR, Ivy DD. Plasma proteomics of differential outcome to long-term therapy in children with idiopathic pulmonary arterial hypertension. Proteomics Clin Appl. 2012 Jun; 6(5-6):257-67. PMID: 22653875; PMCID: PMC3569520.
      View in: PubMed, PubMed Central
    60. Takatsuki S, Rosenzweig EB, Zuckerman W, Brady D, Calderbank M, Ivy DD. Clinical safety, pharmacokinetics, and efficacy of ambrisentan therapy in children with pulmonary arterial hypertension. Pediatr Pulmonol. 2013 Jan; 48(1):27-34. PMID: 22511577; PMCID: PMC3412194.
      View in: PubMed, PubMed Central
    61. Yeager ME, Reddy MB, Nguyen CM, Colvin KL, Ivy DD, Stenmark KR. Activation of the unfolded protein response is associated with pulmonary hypertension. Pulm Circ. 2012 Apr-Jun; 2(2):229-40. PMID: 22837864; PMCID: PMC3401877.
      View in: PubMed, PubMed Central
    62. Barst RJ, Channick R, Ivy D, Goldstein B. Clinical perspectives with long-term pulsed inhaled nitric oxide for the treatment of pulmonary arterial hypertension. Pulm Circ. 2012 Apr-Jun; 2(2):139-47. PMID: 22837854; PMCID: PMC3401867.
      View in: PubMed, PubMed Central
    63. Takatsuki S, Darst JR, Das BB, Fagan TE, Wolfe R, Ivy DD. Clinical manifestations and long-term follow-up in pediatric patients living at altitude with isolated pulmonary artery of ductal origin. Pediatr Cardiol. 2012 Jun; 33(5):775-81. PMID: 22430374; PMCID: PMC3360790.
      View in: PubMed, PubMed Central
    64. Takatsuki S, Calderbank M, Ivy DD. Initial experience with tadalafil in pediatric pulmonary arterial hypertension. Pediatr Cardiol. 2012 Jun; 33(5):683-8. PMID: 22402804; PMCID: PMC3366091.
      View in: PubMed, PubMed Central
    65. Ivy D. Advances in pediatric pulmonary arterial hypertension. Curr Opin Cardiol. 2012 Mar; 27(2):70-81. PMID: 22274573; PMCID: PMC3319159.
      View in: PubMed, PubMed Central
    66. Stoica S, Carpenter E, Campbell D, Mitchell M, da Cruz E, Ivy D, Lacour-Gayet F. Morbidity of the arterial switch operation. Ann Thorac Surg. 2012 Jun; 93(6):1977-83. PMID: 22365263; PMCID: PMC3381339.
      View in: PubMed, PubMed Central
    67. Takatsuki S, Wagner BD, Ivy DD. B-type natriuretic peptide and amino-terminal pro-B-type natriuretic peptide in pediatric patients with pulmonary arterial hypertension. Congenit Heart Dis. 2012 May-Jun; 7(3):259-67. PMID: 22325151; PMCID: PMC3355223.
      View in: PubMed, PubMed Central
    68. Berger RM, Beghetti M, Humpl T, Raskob GE, Ivy DD, Jing ZC, Bonnet D, Schulze-Neick I, Barst RJ. Clinical features of paediatric pulmonary hypertension: a registry study. Lancet. 2012 Feb 11; 379(9815):537-46. PMID: 22240409; PMCID: PMC3426911.
      View in: PubMed, PubMed Central
    69. Feinstein JA, Benson DW, Dubin AM, Cohen MS, Maxey DM, Mahle WT, Pahl E, Villafañe J, Bhatt AB, Peng LF, Johnson BA, Marsden AL, Daniels CJ, Rudd NA, Caldarone CA, Mussatto KA, Morales DL, Ivy DD, Gaynor JW, Tweddell JS, Deal BJ, Furck AK, Rosenthal GL, Ohye RG, Ghanayem NS, Cheatham JP, Tworetzky W, Martin GR. Hypoplastic left heart syndrome: current considerations and expectations. J Am Coll Cardiol. 2012 Jan 03; 59(1 Suppl):S1-42. PMID: 22192720.
      View in: PubMed
    70. Yeager ME, Belchenko DD, Nguyen CM, Colvin KL, Ivy DD, Stenmark KR. Endothelin-1, the unfolded protein response, and persistent inflammation: role of pulmonary artery smooth muscle cells. Am J Respir Cell Mol Biol. 2012 Jan; 46(1):14-22. PMID: 21778413; PMCID: PMC3262656.
      View in: PubMed, PubMed Central
    71. Barst RJ, Ivy DD, Gaitan G, Szatmari A, Rudzinski A, Garcia AE, Sastry BK, Pulido T, Layton GR, Serdarevic-Pehar M, Wessel DL. A randomized, double-blind, placebo-controlled, dose-ranging study of oral sildenafil citrate in treatment-naive children with pulmonary arterial hypertension. Circulation. 2012 Jan 17; 125(2):324-34. PMID: 22128226.
      View in: PubMed
    72. Barst RJ, McGoon MD, Elliott CG, Foreman AJ, Miller DP, Ivy DD. Survival in childhood pulmonary arterial hypertension: insights from the registry to evaluate early and long-term pulmonary arterial hypertension disease management. Circulation. 2012 Jan 03; 125(1):113-22. PMID: 22086881.
      View in: PubMed
    73. Takatsuki S, Ivy DD, Nuss R. Correlation of N-terminal fragment of B-type natriuretic peptide levels with clinical, laboratory, and echocardiographic abnormalities in children with sickle cell disease. J Pediatr. 2012 Mar; 160(3):428-433.e1. PMID: 22048047; PMCID: PMC3274616.
      View in: PubMed, PubMed Central
    74. Yeager ME, Nguyen CM, Belchenko DD, Colvin KL, Takatsuki S, Ivy DD, Stenmark KR. Circulating myeloid-derived suppressor cells are increased and activated in pulmonary hypertension. Chest. 2012 Apr; 141(4):944-952. PMID: 21940769; PMCID: PMC3318947.
      View in: PubMed, PubMed Central
    75. Lammers AE, Adatia I, Cerro MJ, Diaz G, Freudenthal AH, Freudenthal F, Harikrishnan S, Ivy D, Lopes AA, Raj JU, Sandoval J, Stenmark K, Haworth SG. Functional classification of pulmonary hypertension in children: Report from the PVRI pediatric taskforce, Panama 2011. Pulm Circ. 2011 Aug 02; 1(2):280-285. PMID: 21874157.
      View in: PubMed
    76. Yeager ME, Nguyen CM, Belchenko DD, Colvin KL, Takatsuki S, Ivy DD, Stenmark KR. Circulating fibrocytes are increased in children and young adults with pulmonary hypertension. Eur Respir J. 2012 Jan; 39(1):104-11. PMID: 21700605; PMCID: PMC3319160.
      View in: PubMed, PubMed Central
    77. Abman SH, Ivy DD. Recent progress in understanding pediatric pulmonary hypertension. Curr Opin Pediatr. 2011 Jun; 23(3):298-304. PMID: 21572384; PMCID: PMC3128451.
      View in: PubMed, PubMed Central
    78. Olin J, Abman S, Grady R, Ivy D, Lovell M, Partrick D, Balasubramaniam V. A 7-year-old with pulmonary hypertension. BMJ Case Rep. 2011; 2011:bcr0220113843. PMID: 21897452; PMCID: PMC3082056.
      View in: PubMed, PubMed Central
    79. Takatsuki S, Soep JB, Calderbank M, Ivy DD. Connective tissue disease presenting with signs and symptoms of pulmonary hypertension in children. Pediatr Cardiol. 2011 Aug; 32(6):828-33. PMID: 21448619; PMCID: PMC3142789.
      View in: PubMed, PubMed Central
    80. Mallory GB, Hanna BD, Ivy DD, Shardonofsky F, Farber HJ. Management and Controversies in Pediatric Pulmonary Hypertension. Pediatr Allergy Immunol Pulmonol. 2011 Mar 04; 22(4):139-150. PMID: 21766047.
      View in: PubMed
    81. Barst RJ, Ertel SI, Beghetti M, Ivy DD. Pulmonary arterial hypertension: a comparison between children and adults. Eur Respir J. 2011 Mar; 37(3):665-77. PMID: 21357924; PMCID: PMC3128436.
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    82. Cerro MJ, Abman S, Diaz G, Freudenthal AH, Freudenthal F, Harikrishnan S, Haworth SG, Ivy D, Lopes AA, Raj JU, Sandoval J, Stenmark K, Adatia I. A consensus approach to the classification of pediatric pulmonary hypertensive vascular disease: Report from the PVRI Pediatric Taskforce, Panama 2011. Pulm Circ. 2011; 1(2):286-298. PMID: 21874158.
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    83. Hunter KS, Feinstein JA, Ivy DD, Shandas R. Computational Simulation of the Pulmonary Arteries and its Role in the Study of Pediatric Pulmonary Hypertension. Prog Pediatr Cardiol. 2010 Dec 01; 30(1-2):63-69. PMID: 21499523.
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    84. Hill KD, Lim DS, Everett AD, Ivy DD, Moore JD. Assessment of pulmonary hypertension in the pediatric catheterization laboratory: current insights from the Magic registry. Catheter Cardiovasc Interv. 2010 Nov 15; 76(6):865-73. PMID: 20549685; PMCID: PMC3116922.
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    85. Ivy DD, Rosenzweig EB, Lemarié JC, Brand M, Rosenberg D, Barst RJ. Long-term outcomes in children with pulmonary arterial hypertension treated with bosentan in real-world clinical settings. Am J Cardiol. 2010 Nov 01; 106(9):1332-8. PMID: 21029834; PMCID: PMC2966874.
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    86. Phelps CM, Tissot C, Buckvold S, Gralla J, Ivy DD, Pietra BA, Miyamoto SD. Outcome of acute graft rejection associated with hemodynamic compromise in pediatric heart transplant recipients. Pediatr Cardiol. 2011 Jan; 32(1):1-7. PMID: 20963408; PMCID: PMC3120936.
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    87. Tissot C, Ivy DD, Beghetti M. Medical therapy for pediatric pulmonary arterial hypertension. J Pediatr. 2010 Oct; 157(4):528-32. PMID: 20656296; PMCID: PMC3127257.
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    88. Law YM, Mack CL, Sokol RJ, Rice M, Parsley L, Ivy D. Cardiopulmonary manifestations of portovenous shunts from congenital absence of the portal vein: pulmonary hypertension and pulmonary vascular dilatation. Pediatr Transplant. 2011 Dec; 15(8):E162-8. PMID: 20565694; PMCID: PMC3203339.
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    89. Ivy D, Saji BT. A New Era in Medical Management of Severe Pediatric Pulmonary Arterial Hypertension. Nihon Shoni Junkanki Gakkai Zasshi. 2010 Jun 04; 26(3):206-218. PMID: 23264720.
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    90. Tian L, Hunter KS, Kirby KS, Ivy DD, Shandas R. Measurement uncertainty in pulmonary vascular input impedance and characteristic impedance estimated from pulsed-wave Doppler ultrasound and pressure: clinical studies on 57 pediatric patients. Physiol Meas. 2010 Jun; 31(6):729-48. PMID: 20410558; PMCID: PMC3010409.
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    91. Ivy DD. Prostacyclin in the intensive care setting. Pediatr Crit Care Med. 2010 Mar; 11(2 Suppl):S41-5. PMID: 20216163; PMCID: PMC3116926.
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    92. Beghetti M, Haworth SG, Bonnet D, Barst RJ, Acar P, Fraisse A, Ivy DD, Jais X, Schulze-Neick I, Galiè N, Morganti A, Dingemanse J, Kusic-Pajic A, Berger RM. Pharmacokinetic and clinical profile of a novel formulation of bosentan in children with pulmonary arterial hypertension: the FUTURE-1 study. Br J Clin Pharmacol. 2009 Dec; 68(6):948-55. PMID: 20002090; PMCID: PMC2805863.
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    93. Ivy DD, Feinstein JA, Humpl T, Rosenzweig EB. Non-congenital heart disease associated pediatric pulmonary arterial hypertension. Prog Pediatr Cardiol. 2009 Dec 01; 27(1-2):13-23. PMID: 21852894.
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    94. Rosenzweig EB, Feinstein JA, Humpl T, Ivy DD. Pulmonary arterial hypertension in children: Diagnostic work-up and challenges. Prog Pediatr Cardiol. 2009 Dec; 27(1):4-11. PMID: 21691442.
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    95. Ye M, Coldren C, Liang X, Mattina T, Goldmuntz E, Benson DW, Ivy D, Perryman MB, Garrett-Sinha LA, Grossfeld P. Deletion of ETS-1, a gene in the Jacobsen syndrome critical region, causes ventricular septal defects and abnormal ventricular morphology in mice. Hum Mol Genet. 2010 Feb 15; 19(4):648-56. PMID: 19942620; PMCID: PMC2807373.
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    96. Whitworth JR, Ivy DD, Gralla J, Narkewicz MR, Sokol RJ. Pulmonary vascular complications in asymptomatic children with portal hypertension. J Pediatr Gastroenterol Nutr. 2009 Nov; 49(5):607-12. PMID: 19820411; PMCID: PMC2783348.
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    97. Ivy DD, Calderbank M, Wagner BD, Dolan S, Nyquist AC, Wade M, Nickels WM, Doran AK. Closed-hub systems with protected connections and the reduction of risk of catheter-related bloodstream infection in pediatric patients receiving intravenous prostanoid therapy for pulmonary hypertension. Infect Control Hosp Epidemiol. 2009 Sep; 30(9):823-9. PMID: 19637961; PMCID: PMC3117306.
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    98. Tissot C, Buckvold S, Phelps CM, Ivy DD, Campbell DN, Mitchell MB, da Cruz SO, Pietra BA, Miyamoto SD. Outcome of extracorporeal membrane oxygenation for early primary graft failure after pediatric heart transplantation. J Am Coll Cardiol. 2009 Aug 18; 54(8):730-7. PMID: 19679252; PMCID: PMC3117294.
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    99. Miyamoto SD, Pietra BA, Chan KC, Ivy DD, Mashburn C, Campbell DN, Mitchell MB, Boucek MM. Long-term outcome of palliation with internal pulmonary artery bands after primary heart transplantation for hypoplastic left heart syndrome. Pediatr Cardiol. 2009 May; 30(4):419-25. PMID: 19365660; PMCID: PMC3117302.
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    100. Morchi GS, Ivy DD, Duster MC, Claussen L, Chan KC, Kay J. Sildenafil Increases Systemic Saturation and Reduces Pulmonary Artery Pressure in Patients with Failing Fontan Physiology. Congenit Heart Dis. 2009 Apr; 4(2):107-111. PMID: 21866231.
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    101. Goldberg SP, McCanta AC, Campbell DN, Carpenter EV, Clarke DR, da Cruz E, Ivy DD, Lacour-Gayet FG. Implications of incising the ventricular septum in double outlet right ventricle and in the Ross-Konno operation. Eur J Cardiothorac Surg. 2009 Apr; 35(4):589-93; discussion 593. PMID: 19269838; PMCID: PMC3117298.
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    102. Mourani PM, Sontag MK, Ivy DD, Abman SH. Effects of long-term sildenafil treatment for pulmonary hypertension in infants with chronic lung disease. J Pediatr. 2009 Mar; 154(3):379-84, 384.e1-2. PMID: 18950791; PMCID: PMC2783835.
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    103. Phelps CM, Mengshol S, Ivy DD. A curious isolated cystic lesion of the membranous atrioventricular septum. Cardiol Young. 2008 Dec; 18(6):631-4. PMID: 18950547; PMCID: PMC3118089.
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    104. Coldren CD, Lai Z, Shragg P, Rossi E, Glidewell SC, Zuffardi O, Mattina T, Ivy DD, Curfs LM, Mattson SN, Riley EP, Treier M, Grossfeld PD. Chromosomal microarray mapping suggests a role for BSX and Neurogranin in neurocognitive and behavioral defects in the 11q terminal deletion disorder (Jacobsen syndrome). Neurogenetics. 2009 Apr; 10(2):89-95. PMID: 18855024; PMCID: PMC3050515.
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    105. Bernus A, Wagner BD, Accurso F, Doran A, Kaess H, Ivy DD. Brain natriuretic peptide levels in managing pediatric patients with pulmonary arterial hypertension. Chest. 2009 Mar; 135(3):745-751. PMID: 18849405; PMCID: PMC2715554.
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    106. Malhotra SP, Lacour-Gayet F, Campbell DN, Miyamoto S, Clarke DR, Dines ML, Ivy DD, Mitchell MB. Outcomes of reparative and transplantation strategies for multilevel left heart obstructions with mitral stenosis. Ann Thorac Surg. 2008 Oct; 86(4):1305-9; discussion 1310. PMID: 18805182; PMCID: PMC3128450.
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    107. Malhotra SP, Ivy DD, Mitchell MB, Campbell DN, Dines ML, Miyamoto S, Kay J, Clarke DR, Lacour-Gayet F. Performance of cavopulmonary palliation at elevated altitude: midterm outcomes and risk factors for failure. Circulation. 2008 Sep 30; 118(14 Suppl):S177-81. PMID: 18824752; PMCID: PMC3129266.
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    108. Drexler ES, Bischoff JE, Slifka AJ, McCowan CN, Quinn TP, Shandas R, Ivy DD, Stenmark KR. Stiffening of the Extrapulmonary Arteries From Rats in Chronic Hypoxic Pulmonary Hypertension. J Res Natl Inst Stand Technol. 2008 Jul-Aug; 113(4):239-49. PMID: 27096124; PMCID: PMC4651618.
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    109. Doran AK, Ivy DD, Barst RJ, Hill N, Murali S, Benza RL. Guidelines for the prevention of central venous catheter-related blood stream infections with prostanoid therapy for pulmonary arterial hypertension. Int J Clin Pract Suppl. 2008 Jul; (160):5-9. PMID: 18638170; PMCID: PMC3129264.
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    110. Villavicencio K, Ivy D, Cole L, Nuss R. Symptomatic pulmonary hypertension in a child with sickle cell disease. J Pediatr. 2008 Jun; 152(6):879-81. PMID: 18492535; PMCID: PMC3128440.
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    111. Hunter KS, Gross JK, Lanning CJ, Kirby KS, Dyer KL, Ivy DD, Shandas R. Noninvasive methods for determining pulmonary vascular function in children with pulmonary arterial hypertension: application of a mechanical oscillator model. Congenit Heart Dis. 2008 Mar-Apr; 3(2):106-16. PMID: 18380759; PMCID: PMC3116924.
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    112. Mourani PM, Ivy DD, Rosenberg AA, Fagan TE, Abman SH. Left ventricular diastolic dysfunction in bronchopulmonary dysplasia. J Pediatr. 2008 Feb; 152(2):291-3. PMID: 18206706; PMCID: PMC2259289.
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    113. Mourani PM, Sontag MK, Younoszai A, Ivy DD, Abman SH. Clinical utility of echocardiography for the diagnosis and management of pulmonary vascular disease in young children with chronic lung disease. Pediatrics. 2008 Feb; 121(2):317-25. PMID: 18245423; PMCID: PMC3121163.
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    114. Ivy DD, Doran AK, Smith KJ, Mallory GB, Beghetti M, Barst RJ, Brady D, Law Y, Parker D, Claussen L, Abman SH. Short- and long-term effects of inhaled iloprost therapy in children with pulmonary arterial hypertension. J Am Coll Cardiol. 2008 Jan 15; 51(2):161-9. PMID: 18191742; PMCID: PMC3125969.
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    115. Hunter KS, Lee PF, Lanning CJ, Ivy DD, Kirby KS, Claussen LR, Chan KC, Shandas R. Pulmonary vascular input impedance is a combined measure of pulmonary vascular resistance and stiffness and predicts clinical outcomes better than pulmonary vascular resistance alone in pediatric patients with pulmonary hypertension. Am Heart J. 2008 Jan; 155(1):166-74. PMID: 18082509; PMCID: PMC3139982.
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    116. Yetman AT, Beroukhim RS, Ivy DD, Manchester D. Importance of the clinical recognition of Loeys-Dietz syndrome in the neonatal period. Pediatrics. 2007 May; 119(5):e1199-202. PMID: 17470566; PMCID: PMC3131201.
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    117. Zhang Y, Dunn ML, Hunter KS, Lanning C, Ivy DD, Claussen L, Chen SJ, Shandas R. Application of a microstructural constitutive model of the pulmonary artery to patient-specific studies: validation and effect of orthotropy. J Biomech Eng. 2007 Apr; 129(2):193-201. PMID: 17408324; PMCID: PMC3114451.
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    118. Carmosino MJ, Friesen RH, Doran A, Ivy DD. Perioperative complications in children with pulmonary hypertension undergoing noncardiac surgery or cardiac catheterization. Anesth Analg. 2007 Mar; 104(3):521-7. PMID: 17312201; PMCID: PMC1934984.
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    119. Ivy DD, Claussen L, Doran A. Transition of stable pediatric patients with pulmonary arterial hypertension from intravenous epoprostenol to intravenous treprostinil. Am J Cardiol. 2007 Mar 01; 99(5):696-8. PMID: 17317374; PMCID: PMC1974790.
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    120. Artrip JH, Campbell DN, Ivy DD, Almodovar MC, Chan KC, Mitchell MB, Clarke DR, Lacour-Gayet F. Birth weight and complexity are significant factors for the management of hypoplastic left heart syndrome. Ann Thorac Surg. 2006 Oct; 82(4):1252-7; discussion 1258-9. PMID: 16996917.
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    121. Hunter KS, Lanning CJ, Chen SY, Zhang Y, Garg R, Ivy DD, Shandas R. Simulations of congenital septal defect closure and reactivity testing in patient-specific models of the pediatric pulmonary vasculature: A 3D numerical study with fluid-structure interaction. J Biomech Eng. 2006 Aug; 128(4):564-72. PMID: 16813447; PMCID: PMC4050970.
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    122. Drexler ES, Quinn TP, Slifka AJ, McCowan CN, Bischoff JE, Wright JE, Ivy DD, Shandas R. Comparison of mechanical behavior among the extrapulmonary arteries from rats. J Biomech. 2007; 40(4):812-9. PMID: 16682044.
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    123. Dyer K, Lanning C, Das B, Lee PF, Ivy DD, Valdes-Cruz L, Shandas R. Noninvasive Doppler tissue measurement of pulmonary artery compliance in children with pulmonary hypertension. J Am Soc Echocardiogr. 2006 Apr; 19(4):403-12. PMID: 16581479; PMCID: PMC2003158.
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    124. Dyer KL, Pauliks LB, Das B, Shandas R, Ivy D, Shaffer EM, Valdes-Cruz LM. Use of myocardial performance index in pediatric patients with idiopathic pulmonary arterial hypertension. J Am Soc Echocardiogr. 2006 Jan; 19(1):21-7. PMID: 16423665; PMCID: PMC1934985.
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    125. Imamura M, Vitello AM, Limbird JN, Ivy DD, Fallon MB, Carter EP. Endothelin-B receptor overexpression prevents hypoxic pulmonary hypertension in cirrhotic rats. Chest. 2005 Dec; 128(6 Suppl):580S-581S. PMID: 16373843.
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    126. Ihida-Stansbury K, McKean DM, Gebb SA, Martin JF, Stevens T, Nemenoff R, Vaughn J, Lane K, Loyd J, Wheeler L, Morrell NW, Ivy D, Jones PL. Regulation and functions of the paired-related homeobox gene PRX1 in pulmonary vascular development and disease. Chest. 2005 Dec; 128(6 Suppl):591S. PMID: 16373852.
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    127. Resnik E, Herron J, Fu R, Ivy DD, Cornfield DN. Oxygen tension modulates the expression of pulmonary vascular BKCa channel alpha- and beta-subunits. Am J Physiol Lung Cell Mol Physiol. 2006 Apr; 290(4):L761-L768. PMID: 16284215.
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    128. Rosenzweig EB, Ivy DD, Widlitz A, Doran A, Claussen LR, Yung D, Abman SH, Morganti A, Nguyen N, Barst RJ. Effects of long-term bosentan in children with pulmonary arterial hypertension. J Am Coll Cardiol. 2005 Aug 16; 46(4):697-704. PMID: 16098438.
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    129. Zhang Y, Dunn ML, Drexler ES, McCowan CN, Slifka AJ, Ivy DD, Shandas R. A microstructural hyperelastic model of pulmonary arteries under normo- and hypertensive conditions. Ann Biomed Eng. 2005 Aug; 33(8):1042-52. PMID: 16133913.
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    130. Condino AA, Ivy DD, O'Connor JA, Narkewicz MR, Mengshol S, Whitworth JR, Claussen L, Doran A, Sokol RJ. Portopulmonary hypertension in pediatric patients. J Pediatr. 2005 Jul; 147(1):20-6. PMID: 16027687; PMCID: PMC3326402.
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    131. Ivy DD, McMurtry IF, Colvin K, Imamura M, Oka M, Lee DS, Gebb S, Jones PL. Development of occlusive neointimal lesions in distal pulmonary arteries of endothelin B receptor-deficient rats: a new model of severe pulmonary arterial hypertension. Circulation. 2005 Jun 07; 111(22):2988-96. PMID: 15927975; PMCID: PMC1934986.
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    132. Kinsella JP, Ivy DD, Abman SH. Pulmonary vasodilator therapy in congenital diaphragmatic hernia: acute, late, and chronic pulmonary hypertension. Semin Perinatol. 2005 Apr; 29(2):123-8. PMID: 16052736.
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    133. Das BB, Narkewicz MR, Sokol RJ, Chen YT, Bali D, Li SC, Matthews MR, Mierau GW, Ivy DD. Amylopectinosis disease isolated to the heart with normal glycogen branching enzyme activity and gene sequence. Pediatr Transplant. 2005 Apr; 9(2):261-5. PMID: 15787805.
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    134. Yetman AT, Taylor AL, Doran A, Ivy DD. Utility of cardiopulmonary stress testing in assessing disease severity in children with pulmonary arterial hypertension. Am J Cardiol. 2005 Mar 01; 95(5):697-9. PMID: 15721127.
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    135. Rashid A, Ivy D. Severe paediatric pulmonary hypertension: new management strategies. Arch Dis Child. 2005 Jan; 90(1):92-8. PMID: 15613526; PMCID: PMC1720073.
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    136. Das BB, Wolfe RR, Chan KC, Larsen GL, Reeves JT, Ivy D. High-altitude pulmonary edema in children with underlying cardiopulmonary disorders and pulmonary hypertension living at altitude. Arch Pediatr Adolesc Med. 2004 Dec; 158(12):1170-6. PMID: 15583103.
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    137. Imamura M, Luo B, Limbird J, Vitello A, Oka M, Ivy DD, McMurtry IF, Garat CV, Fallon MB, Carter EP. Hypoxic pulmonary hypertension is prevented in rats with common bile duct ligation. J Appl Physiol (1985). 2005 Feb; 98(2):739-47. PMID: 15516365.
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    138. Weinberg CE, Hertzberg JR, Ivy DD, Kirby KS, Chan KC, Valdes-Cruz L, Shandas R. Extraction of pulmonary vascular compliance, pulmonary vascular resistance, and right ventricular work from single-pressure and Doppler flow measurements in children with pulmonary hypertension: a new method for evaluating reactivity: in vitro and clinical studies. Circulation. 2004 Oct 26; 110(17):2609-17. PMID: 15492299.
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    139. Hartsfield CL, McMurtry IF, Ivy DD, Morris KG, Vidmar S, Rodman DM, Fagan KA. Cardioprotective and vasomotor effects of HO activity during acute and chronic hypoxia. Am J Physiol Heart Circ Physiol. 2004 Nov; 287(5):H2009-15. PMID: 15217799.
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    140. Ivy DD, Lee DS, Rairigh RL, Parker TA, Abman SH. Endothelin B receptor blockade attenuates pulmonary vasodilation in oxygen-ventilated fetal lambs. Biol Neonate. 2004; 86(3):155-9. PMID: 15205573.
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    141. Mourani PM, Ivy DD, Gao D, Abman SH. Pulmonary vascular effects of inhaled nitric oxide and oxygen tension in bronchopulmonary dysplasia. Am J Respir Crit Care Med. 2004 Nov 01; 170(9):1006-13. PMID: 15184202.
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    142. Ivy DD, Doran A, Claussen L, Bingaman D, Yetman A. Weaning and discontinuation of epoprostenol in children with idiopathic pulmonary arterial hypertension receiving concomitant bosentan. Am J Cardiol. 2004 Apr 01; 93(7):943-6. PMID: 15050507; PMCID: PMC3138203.
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    143. Fagan KA, Oka M, Bauer NR, Gebb SA, Ivy DD, Morris KG, McMurtry IF. Attenuation of acute hypoxic pulmonary vasoconstriction and hypoxic pulmonary hypertension in mice by inhibition of Rho-kinase. Am J Physiol Lung Cell Mol Physiol. 2004 Oct; 287(4):L656-64. PMID: 14977625.
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    144. Drexler ES, McCowan CN, Wright JE, Slifka AJ, Ivy DD, Shandas R. Comparison of strength properties of normotensive and hypertensive rat pulmonary arteries. Biomed Sci Instrum. 2004; 40:297-302. PMID: 15133974.
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    145. Das BB, Sahoo S, Ivy DD. Neonatal aortic arch thrombosis masquerading as coarctation of the aorta. Pediatr Cardiol. 2004 Jan-Feb; 25(1):80-3. PMID: 14583833.
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    146. Ivy DD, Parker D, Doran A, Parker D, Kinsella JP, Abman SH. Acute hemodynamic effects and home therapy using a novel pulsed nasal nitric oxide delivery system in children and young adults with pulmonary hypertension. Am J Cardiol. 2003 Oct 01; 92(7):886-90. PMID: 14516902.
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    147. Bourke KD, Sondheimer HM, Ivy DD, Pietra B, Gleason BK, Mashburn C, Boucek MM. Improved pretransplant management of infants with hypoplastic left heart syndrome enables discharge to home while waiting for transplantation. Pediatr Cardiol. 2003 Nov-Dec; 24(6):538-43. PMID: 12947507.
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    148. Carpenter T, Schomberg S, Steudel W, Ozimek J, Colvin K, Stenmark K, Ivy DD. Endothelin B receptor deficiency predisposes to pulmonary edema formation via increased lung vascular endothelial cell growth factor expression. Circ Res. 2003 Sep 05; 93(5):456-63. PMID: 12919946.
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    149. Drexler ES, Slifka AJ, Wright JE, McCowan CN, Finch DS, Quinn TP, McColskey JD, Ivy DD, Shandas R. An Experimental Method for Measuring Mechanical Properties of Rat Pulmonary Arteries Verified With Latex. J Res Natl Inst Stand Technol. 2003 May-Jun; 108(3):183-91. PMID: 27413604; PMCID: PMC4844506.
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    150. Mitchell MB, Campbell DN, Boucek MM, Sondheimer HM, Chan KC, Ivy DD, Pietra B, Mackenzie T. Mechanical limitation of pulmonary blood flow facilitates heart transplantation in older infants with hypoplastic left heart syndrome. Eur J Cardiothorac Surg. 2003 May; 23(5):735-42. PMID: 12754026.
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    151. Kinsella JP, Parker TA, Ivy DD, Abman SH. Noninvasive delivery of inhaled nitric oxide therapy for late pulmonary hypertension in newborn infants with congenital diaphragmatic hernia. J Pediatr. 2003 Apr; 142(4):397-401. PMID: 12712057.
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    152. Balasubramaniam V, Le Cras TD, Ivy DD, Grover TR, Kinsella JP, Abman SH. Role of platelet-derived growth factor in vascular remodeling during pulmonary hypertension in the ovine fetus. Am J Physiol Lung Cell Mol Physiol. 2003 May; 284(5):L826-33. PMID: 12533438.
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    153. Balzer DT, Kort HW, Day RW, Corneli HM, Kovalchin JP, Cannon BC, Kaine SF, Ivy DD, Webber SA, Rothman A, Ross RD, Aggarwal S, Takahashi M, Waldman JD. Inhaled Nitric Oxide as a Preoperative Test (INOP Test I): the INOP Test Study Group. Circulation. 2002 Sep 24; 106(12 Suppl 1):I76-81. PMID: 12354713.
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    154. Arce OX, Knudson OA, Ellison MC, Baselga P, Ivy DD, Degroff C, Valdes-Cruz L. Longitudinal motion of the atrioventricular annuli in children: reference values, growth related changes, and effects of right ventricular volume and pressure overload. J Am Soc Echocardiogr. 2002 Sep; 15(9):906-16. PMID: 12221407.
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    155. Ivy DD, Yanagisawa M, Gariepy CE, Gebb SA, Colvin KL, McMurtry IF. Exaggerated hypoxic pulmonary hypertension in endothelin B receptor-deficient rats. Am J Physiol Lung Cell Mol Physiol. 2002 Apr; 282(4):L703-12. PMID: 11880295.
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    156. Epting CL, Wolfe RR, Abman SH, Deutsch GH, Ivy D. Reversal of pulmonary hypertension associated with plexiform lesions in congenital heart disease: a case report. Pediatr Cardiol. 2002 Mar-Apr; 23(2):182-5. PMID: 11889532.
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    157. Shandas R, Weinberg C, Ivy DD, Nicol E, DeGroff CG, Hertzberg J, Valdes-Cruz L. Development of a noninvasive ultrasound color M-mode means of estimating pulmonary vascular resistance in pediatric pulmonary hypertension: mathematical analysis, in vitro validation, and preliminary clinical studies. Circulation. 2001 Aug 21; 104(8):908-13. PMID: 11514378.
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    158. Ivy D. Diagnosis and treatment of severe pediatric pulmonary hypertension. Cardiol Rev. 2001 Jul-Aug; 9(4):227-37. PMID: 11405903.
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    159. Ivy D, McMurtry IF, Yanagisawa M, Gariepy CE, Le Cras TD, Gebb SA, Morris KG, Wiseman RC, Abman SH. Endothelin B receptor deficiency potentiates ET-1 and hypoxic pulmonary vasoconstriction. Am J Physiol Lung Cell Mol Physiol. 2001 May; 280(5):L1040-8. PMID: 11290529.
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    160. Rairigh RL, Parker TA, Ivy DD, Kinsella JP, Fan ID, Abman SH. Role of inducible nitric oxide synthase in the pulmonary vascular response to birth-related stimuli in the ovine fetus. Circ Res. 2001 Apr 13; 88(7):721-6. PMID: 11304495.
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    161. Torielli F, Fashaw LM, Knudson O, Kinsella J, Ivy D, Valdes-Cruz L, Rosenberg A. Echocardiographic outcome of infants treated as newborns with inhaled nitric oxide for severe hypoxemic respiratory failure. J Pediatr. 2001 Mar; 138(3):349-54. PMID: 11241041.
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    162. Ivy D, Eells P. Diagnosis and treatment of pulmonary hypertension in the adolescent. Adolesc Med. 2001 Feb; 12(1):79-93. PMID: 11224024.
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    163. Boucek MM, Sondheimer HM, Ivy DD, Shaffer EM, Mashburn C, Ripe DW, Gilbert DJ, Kyle TE, Campbell DN, Pietra B. Transplant coronary artery disease in pediatrics: favorable outcome with medical therapy. J Heart Lung Transplant. 2001 Feb; 20(2):261. PMID: 11250528.
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    164. Pietra B, Ivy DD, Sondheimer HM, Shaffer EM, Mashburn C, Ripe DW, Gilbert DJ, Kyle TE, Mitchell MB, Campbell DN, Boucek MM. Comparison of pretransplant transfusion with or without cyclosporin inhibition on post transplant outcome. J Heart Lung Transplant. 2001 Feb; 20(2):222-223. PMID: 11250414.
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    165. Ivy DD, Parker TA, Abman SH. Prolonged endothelin B receptor blockade causes pulmonary hypertension in the ovine fetus. Am J Physiol Lung Cell Mol Physiol. 2000 Oct; 279(4):L758-65. PMID: 11000137.
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    166. Ivy DD, le Cras TD, Parker TA, Zenge JP, Jakkula M, Markham NE, Kinsella JP, Abman SH. Developmental changes in endothelin expression and activity in the ovine fetal lung. Am J Physiol Lung Cell Mol Physiol. 2000 Apr; 278(4):L785-93. PMID: 10749756.
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    167. Parker TA, Ivy DD, Galan HL, Grover TR, Kinsella JP, Abman SH. Estradiol improves pulmonary hemodynamics and vascular remodeling in perinatal pulmonary hypertension. Am J Physiol Lung Cell Mol Physiol. 2000 Feb; 278(2):L374-81. PMID: 10666122.
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    168. Holcomb RG, Tyson RW, Ivy DD, Abman SH, Kinsella JP. Congenital pulmonary venous stenosis presenting as persistent pulmonary hypertension of the newborn. Pediatr Pulmonol. 1999 Oct; 28(4):301-6. PMID: 10497380.
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    169. Ziegler JW, Ivy DD, Wiggins JW, Kinsella JP, Clarke WR, Abman SH. Effects of dipyridamole and inhaled nitric oxide in pediatric patients with pulmonary hypertension. Am J Respir Crit Care Med. 1998 Nov; 158(5 Pt 1):1388-95. PMID: 9817684.
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    170. Ivy DD, Griebel JL, Kinsella JP, Abman SH. Acute hemodynamic effects of pulsed delivery of low flow nasal nitric oxide in children with pulmonary hypertension. J Pediatr. 1998 Sep; 133(3):453-6. PMID: 9738734.
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    171. Ivy DD, Parker TA, Kinsella JP, Abman SH. Endothelin A receptor blockade decreases pulmonary vascular resistance in premature lambs with hyaline membrane disease. Pediatr Res. 1998 Aug; 44(2):175-80. PMID: 9702910.
      View in: PubMed
    172. Ivy DD, Ziegler JW, Kinsella JP, Wiggins JW, Abman SH. Hemodynamic effects of dipyridamole and inhaled nitric oxide in pediatric patients with pulmonary hypertension. Chest. 1998 Jul; 114(1 Suppl):17S. PMID: 9676605.
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    173. Ivy DD, Le Cras TD, Horan MP, Abman SH. Chronic intrauterine pulmonary hypertension increases preproendothelin-1 and decreases endothelin B receptor mRNA expression in the ovine fetal lung. Chest. 1998 Jul; 114(1 Suppl):65S. PMID: 9676634.
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    174. Ivy DD, Kinsella JP, Ziegler JW, Abman SH. Dipyridamole attenuates rebound pulmonary hypertension after inhaled nitric oxide withdrawal in postoperative congenital heart disease. J Thorac Cardiovasc Surg. 1998 Apr; 115(4):875-82. PMID: 9576224.
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    175. Ziegler JW, Ivy DD, Fox JJ, Kinsella JP, Clarke WR, Abman SH. Dipyridamole potentiates pulmonary vasodilation induced by acetylcholine and nitric oxide in the ovine fetus. Am J Respir Crit Care Med. 1998 Apr; 157(4 Pt 1):1104-10. PMID: 9563726.
      View in: PubMed
    176. Ivy DD, Le Cras TD, Horan MP, Abman SH. Increased lung preproET-1 and decreased ETB-receptor gene expression in fetal pulmonary hypertension. Am J Physiol. 1998 Apr; 274(4 Pt 1):L535-41. PMID: 9575871.
      View in: PubMed
    177. Ivy DD, Neish SR, Knudson OA, Nihill MR, Schaffer MS, Tyson RW, Abman SH, Shaffer EM, Valdes-Cruz L. Intravascular ultrasonic characteristics and vasoreactivity of the pulmonary vasculature in children with pulmonary hypertension. Am J Cardiol. 1998 Mar 15; 81(6):740-8. PMID: 9527085.
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    178. Rairigh RL, Le Cras TD, Ivy DD, Kinsella JP, Richter G, Horan MP, Fan ID, Abman SH. Role of inducible nitric oxide synthase in regulation of pulmonary vascular tone in the late gestation ovine fetus. J Clin Invest. 1998 Jan 01; 101(1):15-21. PMID: 9421461; PMCID: PMC508535.
      View in: PubMed, PubMed Central
    179. Ivy DD, Parker TA, Ziegler JW, Galan HL, Kinsella JP, Tuder RM, Abman SH. Prolonged endothelin A receptor blockade attenuates chronic pulmonary hypertension in the ovine fetus. J Clin Invest. 1997 Mar 15; 99(6):1179-86. PMID: 9077525; PMCID: PMC507931.
      View in: PubMed, PubMed Central
    180. Parker TA, Ivy DD, Kinsella JP, Torielli F, Ruyle SZ, Thilo EH, Abman SH. Combined therapy with inhaled nitric oxide and intravenous prostacyclin in an infant with alveolar-capillary dysplasia. Am J Respir Crit Care Med. 1997 Feb; 155(2):743-6. PMID: 9032222.
      View in: PubMed
    181. Ivy DD, Kinsella JP, Abman SH. Endothelin blockade augments pulmonary vasodilation in the ovine fetus. J Appl Physiol (1985). 1996 Dec; 81(6):2481-7. PMID: 9018495.
      View in: PubMed
    182. Fox JJ, Ziegler JW, Ivy DD, Halbower AC, Kinsella JP, Abman SH. Role of nitric oxide and cGMP system in regulation of ductus arteriosus tone in ovine fetus. Am J Physiol. 1996 Dec; 271(6 Pt 2):H2638-45. PMID: 8997326.
      View in: PubMed
    183. Abman SH, Ivy DD, Ziegler JW, Kinsella JP. Mechanisms of abnormal vasoreactivity in persistent pulmonary hypertension of the newborn infant. J Perinatol. 1996 Mar-Apr; 16(2 Pt 2 Su):S18-23. PMID: 8732544.
      View in: PubMed
    184. Ivy DD, Ziegler JW, Dubus MF, Fox JJ, Kinsella JP, Abman SH. Chronic intrauterine pulmonary hypertension alters endothelin receptor activity in the ovine fetal lung. Pediatr Res. 1996 Mar; 39(3):435-42. PMID: 8929863.
      View in: PubMed
    185. Ivy DD, Kinsella JP, Wolfe RR, Abman SH. Atrial natriuretic peptide and nitric oxide in children with pulmonary hypertension after surgical repair of congenital heart disease. Am J Cardiol. 1996 Jan 01; 77(1):102-5. PMID: 8540445.
      View in: PubMed
    186. Kinsella JP, Torielli F, Ziegler JW, Ivy DD, Abman SH. Dipyridamole augmentation of response to nitric oxide. Lancet. 1995 Sep 02; 346(8975):647-8. PMID: 7651043.
      View in: PubMed
    187. Ziegler JW, Ivy DD, Fox JJ, Kinsella JP, Clarke WR, Abman SH. Dipyridamole, a cGMP phosphodiesterase inhibitor, causes pulmonary vasodilation in the ovine fetus. Am J Physiol. 1995 Aug; 269(2 Pt 2):H473-9. PMID: 7653611.
      View in: PubMed
    188. Ivy DD, Shaffer EM, Johnson AM, Kimberling WJ, Dobin A, Gabow PA. Cardiovascular abnormalities in children with autosomal dominant polycystic kidney disease. J Am Soc Nephrol. 1995 Jun; 5(12):2032-6. PMID: 7579051.
      View in: PubMed
    189. Ziegler JW, Ivy DD, Kinsella JP, Abman SH. The role of nitric oxide, endothelin, and prostaglandins in the transition of the pulmonary circulation. Clin Perinatol. 1995 Jun; 22(2):387-403. PMID: 7671544.
      View in: PubMed
    190. McQueston JA, Kinsella JP, Ivy DD, McMurtry IF, Abman SH. Chronic pulmonary hypertension in utero impairs endothelium-dependent vasodilation. Am J Physiol. 1995 Jan; 268(1 Pt 2):H288-94. PMID: 7840274.
      View in: PubMed
    191. Kinsella JP, Ivy DD, Abman SH. Ontogeny of NO activity and response to inhaled NO in the developing ovine pulmonary circulation. Am J Physiol. 1994 Nov; 267(5 Pt 2):H1955-61. PMID: 7977827.
      View in: PubMed
    192. Kinsella JP, Ivy DD, Abman SH. Inhaled nitric oxide improves gas exchange and lowers pulmonary vascular resistance in severe experimental hyaline membrane disease. Pediatr Res. 1994 Sep; 36(3):402-8. PMID: 7808839.
      View in: PubMed
    193. Ivy DD, Wiggins JW, Badesch DB, Kinsella JP, Kelminson LL, Abman SH. Nitric oxide and prostacyclin treatment of an infant with primary pulmonary hypertension. Am J Cardiol. 1994 Aug 15; 74(4):414-6. PMID: 8059714.
      View in: PubMed
    194. Ivy DD, Kinsella JP, Abman SH. Physiologic characterization of endothelin A and B receptor activity in the ovine fetal pulmonary circulation. J Clin Invest. 1994 May; 93(5):2141-8. PMID: 8182146; PMCID: PMC294348.
      View in: PubMed, PubMed Central
    195. Ivy D, Kaye J, Flitter D, Wiggins J. Variant angina in an adolescent. Pediatr Cardiol. 1994 Jan-Feb; 15(1):45-7. PMID: 8115273.
      View in: PubMed
    196. Ivy D, Loehr J, Schaffer M. Usefulness of prolonged prostaglandin infusion in neonates with Ebstein's anomaly. Am J Cardiol. 1993 Dec 01; 72(17):1327-9. PMID: 8256717.
      View in: PubMed
    197. Kinsella JP, Neish SR, Ivy DD, Shaffer E, Abman SH. Clinical responses to prolonged treatment of persistent pulmonary hypertension of the newborn with low doses of inhaled nitric oxide. J Pediatr. 1993 Jul; 123(1):103-8. PMID: 8320602.
      View in: PubMed
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