Colorado PROFILES, The Colorado Clinical and Translational Sciences Institute (CCTSI)
Keywords
Last Name
Institution

Kristen Lynn Nowak

TitleProfessor
InstitutionUniversity of Colorado Denver - Anschutz Medical Campus
DepartmentSOM-MED
Phone303/724-4842
    Other Positions
    TitleAsst Professor Adjunct
    InstitutionUniversity of Colorado Boulder
    DepartmentIntegrative Physiology


    Collapse Biography 
    Collapse education and training
    Marquette University, Milwaukee, WIB.S.12/2005exercise science
    University of Colorado Boulder, Boulder, COM.S.05/2005integrative physiology
    University of Colorado Boulder, Boulder, COPh.D.12/2011integrative physiology
    University of Colorado Anschutz Medical Campus, Aurora, COpostdoctoral09/2014nephrology
    University of Colorado Anschutz Medical Campus, Aurora, COMPH05/2016epidemiology
    Collapse awards and honors
    2020Rising Star Award, Department of Medicine, University of Colorado

    Collapse Overview 

    Collapse Research 
    Collapse research activities and funding
    R01DK138915     (NOWAK, KRISTEN LYNN)Aug 15, 2024 - May 31, 2029
    NIH
    Advancing ADPKD Treatment with GLP-1RA: A Study of Glucagon-Like Peptide-1 Receptor Agonists' Efficacy, Safety, and Mechanism
    Role: Principal Investigator
    R01DK130266     (Nowak, Kristen and Chonchol, Michel)Sep 1, 2021 - Jun 30, 2026
    NIH/NIDDK
    Inspiratory Muscle Strength Training for Treating Elevated Systolic Blood Pressure in Patients with Moderate to Severe CKD
    Role: Principal Investigator (MPI)
    R01DK130266     (CHONCHOL, MICHEL BENJAMIN)Sep 1, 2021 - Jun 30, 2026
    NIH
    Inspiratory muscle strength training for lowering systolic blood pressure in midlife and older adults with chronic kidney disease
    Role: Co-Principal Investigator
    R21DK129720     (Bjornstad, Petter and Gitomer, Berenice)Aug 1, 2021 - Jul 31, 2021
    NIH/NIDDK
    Measuring Metabolically Active Kidney Tissue in Autosomal Dominant Polycystic Kidney Disease
    Role: Co-Investigator
    R01DK129259     (Nowak, Kristen)Jul 1, 2021 - Jun 30, 2026
    NIH/NIDDK
    Daily Caloric Restriction in Overweight and Obese Adults with ADPKD
    Role Description: Principal Investigator
    R01DK129259     (NOWAK, KRISTEN LYNN)Jul 1, 2021 - May 31, 2026
    NIH
    Daily Caloric Restriction in Overweight and Obese Adults with ADPKD
    Role: Principal Investigator
    R21AG068657     (KENDRICK, JESSICA B)Sep 15, 2020 - Aug 31, 2022
    NIH
    Bicarbonate Administration and Cognitive Function in Midlife and Older Adults with CKD
    Role: Co-Investigator
    241G20a     (Nowak, Kristen)Sep 1, 2020 - Aug 31, 2022
    PKD Foundation
    Adiposity and Time Restricted Feeding in ADPKD
    Role: Principal Investigator
    R01DK121516     (CHONCHOL, MICHEL BENJAMIN)May 23, 2019 - Mar 31, 2025
    NIH
    Nicotinamide riboside supplementation for treating arterial stiffness and elevated systolic blood pressure in patients with moderate to severe CKD.
    Role: Co-Investigator
    R03DK118215     (JABLONSKI NOWAK, KRISTEN)Sep 15, 2018 - Jul 31, 2021
    NIH
    Daily caloric restriction and intermittent fasting in overweight and obese adults with autosomal dominant polycystic kidney disease
    Role: Principal Investigator
    CO-J-18-37     (Nowak, Kristen)Mar 23, 2018 - Mar 23, 2019
    CCTSI
    Daily Caloric Restriction and Intermittent Fasting in Overweight and Obese Adults with Autosomal Dominant Polycystic Kidney Disease
    Role Description: This translational pilot and feasibility study will determine the feasibility of delivering a 12 week behavioral weight loss intervention in adults with overweight/obesity and early-stage ADPKD, based on either daily caloric restriction or intermittent fasting, as well as evaluate safety, acceptability, tolerability, and mechanistic insight into biological pathways that may be altered.
    Role: PI
    PRMRP 170914     (Chonchol, Michel)Aug 1, 2017 - Jul 31, 2021
    DOD
    Statin Therapy in Adults with ADPKD
    Role: Co-Investigator
    PRMRP 170914     (Chonchol, Michel)Aug 1, 2017 - Jul 31, 2021
    Department of Defense
    Statin Therapy in Adults with ADPKD
    Role Description: The goal of this clinical trial is to test the efficacy of pravastatin on slowing progression of renal disease in adult patients with early stage ADPKD.
    Role: Co-Investigator
    K01DK103678     (JABLONSKI NOWAK, KRISTEN)Aug 1, 2015 - Jul 31, 2021
    NIH
    Curcumin Therapy to Treat Vascular Dysfunction in Children and Young Adults with ADPKD
    Role Description: The major goal of this project is to examine the effect of curcumin, a naturally occurring polyphenol with the unique ability to activate transcription of key antioxidants, suppress inflammation, and reduce proliferation, on vascular endothelial function and large-elastic artery stiffness in children and young adults with ADPKD.
    Role: Principal Investigator
    R01DK097081     (CHONCHOL, MICHEL BENJAMIN)Jun 7, 2013 - Mar 31, 2017
    NIH
    Mineralocorticoid Antagonism and Endothelial Dysfunction
    Role: Co-Investigator
    12POST11920023     (Nowak Jablonski, Kristen)Jul 1, 2012 - Jun 30, 2014
    American Heart Association
    Interleukin-1 Trap to Treat Vascular Dysfunction in CKD
    Role Description: Post-doctoral fellowship
    Role: Principal Investigator
    F31AG033994     (JABLONSKI, KRISTEN)Jul 1, 2009 - Jun 30, 2011
    NIH
    Vascular Endothelial Dysfunction in Older Adults: Dietary Sodium Restriction
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Lapierre-Nguyen S, Buffington T, Chonchol M, Nowak KL. High-resistance inspiratory muscle strength training: a promising strategy for improving vascular health in chronic kidney disease. Front Physiol. 2025; 16:1582777. PMID: 40352145.
      View in: PubMed
    2. Steele C, Ostrow A, Wang W, Coleman E, George D, Bing K, Ramanathan S, Gregory A, Gitomer BY, Kline TL, Thomas E, Chonchol M, Nowak KL. Time-restricted eating and autosomal dominant polycystic kidney disease: a pilot, randomized clinical trial. Clin Kidney J. 2025 Apr; 18(4):sfaf069. PMID: 40207097.
      View in: PubMed
    3. Nowak KL, Copeland TP, Ku E, Sarnak MJ, Gitomer B, Abebe KZ, Chapman A, Perrone R, Rahbari-Oskoui FF, Steinman T, Yu ASL, Chonchol M. Overweight Status, Obesity, and Progression to ESKD in Patients with Autosomal Dominant Polycystic Kidney Disease. Clin J Am Soc Nephrol. 2025 Apr 01; 20(4):520-528. PMID: 39970002.
      View in: PubMed
    4. Gu JH, Chonchol M, Hoffman C, Miyazaki M, Miyazaki-Anzai S, Nowak K, Jovanovich A. Deoxycholic acid and the risk of death and cardiovascular events among patients with advanced chronic kidney disease. J Nephrol. 2025 Mar; 38(2):799-801. PMID: 39752120.
      View in: PubMed
    5. Nowak KL, Ostrow A, Oh ES, You Z, Chonchol M. Acute Kidney Injury, Mild Cognitive Impairment, and Dementia: A Cohort Study of Patients from SPRINT. Kidney Med. 2025 Mar; 7(3):100962. PMID: 39980936.
      View in: PubMed
    6. Wang W, You Z, Steele CN, Gitomer B, Chonchol M, Nowak KL. Changes in tubular biomarkers with dietary intervention and metformin in patients with autosomal dominant polycystic kidney disease: a post-hoc analysis of two clinical trials. BMC Nephrol. 2024 Jun 25; 25(1):206. PMID: 38918734.
      View in: PubMed
    7. Jovanovich A, Struemph T, You Z, Wang W, Farmer-Bailey H, Bispham N, Levi M, Schwartz GG, Nowak KL, Chonchol M. Effect of Lanthanum Carbonate on Serum Phosphate, Oxidative Stress, and Vascular Dysfunction in CKD: A Mechanistic Randomized Controlled Trial. Kidney360. 2024 Jul 01; 5(7):959-966. PMID: 38781013.
      View in: PubMed
    8. Bjornstad P, Richard G, Choi YJ, Nowak KL, Steele C, Chonchol MB, Nadeau KJ, Vigers T, Pyle L, Tommerdahl K, van Raalte DH, Hilkin A, Driscoll L, Birznieks C, Hopp K, Wang W, Edelstein C, Nelson RG, Gregory AV, Kline TL, Blondin D, Gitomer B. Kidney Energetics and Cyst Burden in Autosomal Dominant Polycystic Kidney Disease: A Pilot Study. Am J Kidney Dis. 2024 Sep; 84(3):286-297.e1. PMID: 38621633.
      View in: PubMed
    9. Nowak KL, Moretti F, Bussola N, Steele CN, Gregory AV, Kline TL, Ramanathan S, Trapletti G, Furlanello C, McCormick L, Chonchol M. Visceral Adiposity and Progression of ADPKD: A Cohort Study of Patients From the TEMPO 3:4 Trial. Am J Kidney Dis. 2024 Sep; 84(3):275-285.e1. PMID: 38608748.
      View in: PubMed
    10. Gitomer BY, Wang W, George D, Coleman E, Nowak KL, Struemph T, Cadnapaphornchai MA, Patel NU, Jovanovich A, Klawitter J, Farmer B, Ostrow A, You Z, Chonchol M. Statin therapy in patients with early-stage autosomal dominant polycystic kidney disease: Design and baseline characteristics. Contemp Clin Trials. 2024 02; 137:107423. PMID: 38151173.
      View in: PubMed
    11. Chebib FT, Nowak KL, Chonchol MB, Bing K, Ghanem A, Rahbari-Oskoui FF, Dahl NK, Mrug M. Polycystic Kidney Disease Diet: What is Known and What is Safe. Clin J Am Soc Nephrol. 2024 May 01; 19(5):664-682. PMID: 37729939.
      View in: PubMed
    12. Oh ES, You Z, Nowak KL, Jovanovich AJ. Sex Differences in Cardiovascular and All-Cause Mortality in Adults with and without CKD: NHANES 1999-2018. Kidney360. 2023 10 01; 4(10):1467-1471. PMID: 37548954.
      View in: PubMed
    13. Kendrick J, You Z, Andrews E, Farmer-Bailey H, Moreau K, Chonchol M, Steele C, Wang W, Nowak KL, Patel N. Sodium Bicarbonate Treatment and Vascular Function in CKD: A Randomized, Double-Blind, Placebo-Controlled Trial. J Am Soc Nephrol. 2023 08 01; 34(8):1433-1444. PMID: 37228030.
      View in: PubMed
    14. Steele CN, Oh ES, Wang W, Farmer-Bailey H, Gitomer BY, Chonchol M, Nowak KL. Cerebrovascular Pulsatility Index Is Reduced in Autosomal Dominant Polycystic Kidney Disease. Am J Nephrol. 2023; 54(5-6):165-174. PMID: 37231790.
      View in: PubMed
    15. Steele CN, Nowak KL. Nonpharmacological Management of Autosomal Dominant Polycystic Kidney Disease. Adv Kidney Dis Health. 2023 05; 30(3):220-227. PMID: 37088524.
      View in: PubMed
    16. Steele CN, Nowak KL. Targeting Glycosphingolipid Metabolism in ADPKD: Another Roadblock for Treatment. Am J Kidney Dis. 2023 05; 81(5):504-506. PMID: 36863942.
      View in: PubMed
    17. Steele CN, Nowak KL. A Step Ahead toward Measuring Pain in Autosomal Dominant Polycystic Kidney Disease (ADPKD). Clin J Am Soc Nephrol. 2023 02 01; 18(2):160-162. PMID: 36754004.
      View in: PubMed
    18. Oh ES, Freeberg KA, Steele CN, Wang W, Farmer-Bailey H, Coppock ME, Seals DR, Chonchol M, Rossman MJ, Craighead DH, Nowak KL. Cerebrovascular pulsatility index is higher in chronic kidney disease. Physiol Rep. 2023 01; 11(1):e15561. PMID: 36636757.
      View in: PubMed
    19. Oh ES, Steele CN, You Z, Nowak KL, Jovanovich AJ. Sex hormones and the risk of cardiovascular disease and mortality in male and female patients with chronic kidney disease: A systematic review and meta-analysis. Physiol Rep. 2022 11; 10(22):e15490. PMID: 36394074.
      View in: PubMed
    20. Steele C, Nowak K. Obesity, Weight Loss, Lifestyle Interventions, and Autosomal Dominant Polycystic Kidney Disease. Kidney Dial. 2022 Mar; 2(1):106-122. PMID: 35350649.
      View in: PubMed
    21. Oh ES, You Z, Nowak KL, Jovanovich AJ. Association of Monocyte Count and Monocyte/Lymphocyte Ratio with the Risk of Cardiovascular Outcomes in Patients with CKD. Kidney360. 2022 04 28; 3(4):657-665. PMID: 35721602.
      View in: PubMed
    22. Hopp K, Catenacci VA, Dwivedi N, Kline TL, Wang W, You Z, Nguyen DT, Bing K, Poudyal B, Johnson GC, Jackman MR, Miller M, Steele CN, Serkova NJ, MacLean PS, Nemenoff RA, Gitomer B, Chonchol M, Nowak KL. Weight loss and cystic disease progression in autosomal dominant polycystic kidney disease. iScience. 2022 Jan 21; 25(1):103697. PMID: 35059607.
      View in: PubMed
    23. Nowak KL, Farmer-Bailey H, Wang W, You Z, Steele C, Cadnapaphornchai MA, Klawitter J, Patel N, George D, Jovanovich A, Soranno DE, Gitomer B, Chonchol M. Curcumin Therapy to Treat Vascular Dysfunction in Children and Young Adults with ADPKD: A Randomized Controlled Trial. Clin J Am Soc Nephrol. 2022 02; 17(2):240-250. PMID: 34907021.
      View in: PubMed
    24. Steele C, You Z, Gitomer BY, Brosnahan GM, Abebe KZ, Braun WE, Chapman AB, Harris PC, Perrone RD, Steinman TI, Torres VE, Yu ASL, Chonchol M, Nowak KL. PKD1 Compared With PKD2 Genotype and Cardiac Hospitalizations in the Halt Progression of Polycystic Kidney Disease Studies. Kidney Int Rep. 2022 Jan; 7(1):117-120. PMID: 35005320.
      View in: PubMed
    25. Nienow MK, Foley SP, Nowak KL, Braunschweig CA, Peterson SJ. Relationship between blood glucose variability and muscle composition in ICU patients receiving nutrition support: A pilot study. Clin Nutr ESPEN. 2021 12; 46:356-360. PMID: 34857220.
      View in: PubMed
    26. Pengshung MH, Bispham NZ, You Z, Oh E, Supiano MA, Chonchol MB, Nowak KL, Jovanovich AJ. Arterial Stiffness Is Independently Associated with Acute Kidney Injury in SPRINT. Clin J Am Soc Nephrol. 2021 10; 16(10):1560-1561. PMID: 34452880.
      View in: PubMed
    27. Brosnahan GM, Wang W, Gitomer B, Struemph T, George D, You Z, Nowak KL, Klawitter J, Chonchol MB. Metformin Therapy in Autosomal Dominant Polycystic Kidney Disease: A Feasibility Study. Am J Kidney Dis. 2022 04; 79(4):518-526. PMID: 34391872.
      View in: PubMed
    28. Nowak KL, Steele C, Gitomer B, Wang W, Ouyang J, Chonchol MB. Overweight and Obesity and Progression of ADPKD. Clin J Am Soc Nephrol. 2021 06; 16(6):908-915. PMID: 34117082.
      View in: PubMed
    29. Nowak KL, Murray K, You Z, Gitomer B, Brosnahan G, Abebe KZ, Braun W, Chapman A, Harris PC, Miskulin D, Perrone R, Torres V, Steinman T, Yu A, Chonchol M. Pain and Obesity in Autosomal Dominant Polycystic Kidney Disease: A Post Hoc Analysis of the Halt Progression of Polycystic Kidney Disease (HALT-PKD) Studies. Kidney Med. 2021 Jul-Aug; 3(4):536-545.e1. PMID: 34401721.
      View in: PubMed
    30. Netea MG, Balkwill F, Chonchol M, Cominelli F, Donath MY, Giamarellos-Bourboulis EJ, Golenbock D, Gresnigt MS, Heneka MT, Hoffman HM, Hotchkiss R, Joosten LAB, Kastner DL, Korte M, Latz E, Libby P, Mandrup-Poulsen T, Mantovani A, Mills KHG, Nowak KL, O'Neill LA, Pickkers P, van der Poll T, Ridker PM, Schalkwijk J, Schwartz DA, Siegmund B, Steer CJ, Tilg H, van der Meer JWM, van de Veerdonk FL, Dinarello CA. Author Correction: A guiding map for inflammation. Nat Immunol. 2021 Feb; 22(2):254. PMID: 33288963.
      View in: PubMed
    31. Nowak KL, Kakkar R, Devalaraja M, Lo L, Park W, Gobburu J, Kling D, Davidson M, Chonchol M. A phase 1 randomized, double-blind, placebo-controlled, cohort dose-escalation study of a human monoclonal antibody to IL-6 in patients with CKD. Kidney 360. 2021; (2):224-235.
    32. Nowak KL, Kakkar R, Devalaraja M, Lo L, Park W, Gobburu J, Kling D, Davidson M, Chonchol M. A Phase 1 Randomized Dose-Escalation Study of a Human Monoclonal Antibody to IL-6 in CKD. Kidney360. 2021 02 25; 2(2):224-235. PMID: 35373026.
      View in: PubMed
    33. Nowak KL, Farmer-Bailey H, Cadnapaphornchai MA, You Z, George D, Wang W, Jovanovich A, Soranno DE, Gitomer B, Chonchol M. Curcumin therapy to treat vascular dysfunction in children and young adults with autosomal dominant polycystic kidney disease: Design and baseline characteristics of participants. Contemp Clin Trials Commun. 2020 Sep; 19:100635. PMID: 33294724.
      View in: PubMed
    34. Grau L, Gitomer B, McNair B, Wolf M, Harris P, Brosnahan G, Torres V, Steinman T, Yu A, Chapman A, Chonchol M, Nowak KL. Interactions between FGF23 and Genotype in Autosomal Dominant Polycystic Kidney Disease. Kidney360. 2020 Jul; 1(7):648-656. PMID: 33305291.
      View in: PubMed
    35. Wang W, Chonchol M, Seals DR, Nowak KL. Dietary sodium restriction decreases urinary NGAL in older adults with moderately elevated systolic blood pressure free from chronic kidney disease. J Investig Med. 2020 10; 68(7):1271-1275. PMID: 32699180.
      View in: PubMed
    36. Nowak KL, Chonchol M, Jovanovich A, You Z, Ambrosius WT, Cho ME, Glasser S, Lash J, Simmons DL, Taylor A, Weiner D, Rastogi A, Oparil S, Supiano MA. Arterial stiffness and kidney disease progression in the systolic blood pressure intervention trial?. Clin Nephrol. 2020 Jul; 94(1):26-35. PMID: 32449678.
      View in: PubMed
    37. Nowak KL, Jovanovich A, Farmer-Bailey H, Bispham N, Struemph T, Malaczewski M, Wang W, Chonchol M. Vascular Dysfunction, Oxidative Stress, and Inflammation in Chronic Kidney Disease. Kidney360. 2020 Jun; 1(6):501-509. PMID: 33305290.
      View in: PubMed
    38. Nowak K. Parenteral Nutrition-Associated Liver Disease. Clin Liver Dis (Hoboken). 2020 Feb; 15(2):59-62. PMID: 32226616.
      View in: PubMed
    39. Nowak KL, Hopp K. Metabolic Reprogramming in Autosomal Dominant Polycystic Kidney Disease: Evidence and Therapeutic Potential. Clin J Am Soc Nephrol. 2020 04 07; 15(4):577-584. PMID: 32086281.
      View in: PubMed
    40. McKeever L, Peterson SJ, Lateef O, Freels S, Fonseca TL, Bocco BMLC, Fernandes GW, Roehl K, Nowak K, Mozer M, Bianco AC, Braunschweig CA. Higher Caloric Exposure in Critically Ill Patients Transiently Accelerates Thyroid Hormone Activation. J Clin Endocrinol Metab. 2020 02 01; 105(2). PMID: 31581295.
      View in: PubMed
    41. Nowak KL, Edelstein CL. Apoptosis and autophagy in polycystic kidney disease (PKD). Cell Signal. 2020 04; 68:109518. PMID: 31881325.
      View in: PubMed
    42. Greenberg JA, Gerhart J, Horst JN, Chen E, Hunter RL, O'Mahony S, Yeow ME, Fosler L, LaGorio LA, Meksraityte E, Weiss TT, Nowak K, Geddes J, Lambe SS, Fenton K, Shah RC. A Multidisciplinary Team-Based Approach to Improve Communication With Surrogates of Patients With Chronic Critical Illness. Am J Hosp Palliat Care. 2020 Mar; 37(3):214-221. PMID: 31526015.
      View in: PubMed
    43. Hanudel MR, Salusky IB, Pereira RC, Wang W, You Z, Nowak KL, Brosnahan GM, Torres VE, Chapman AB, Perrone RD, Steinman TI, Bae KT, Gitomer BY, Chonchol MB. Erythropoietin and Fibroblast Growth Factor 23 in Autosomal Dominant Polycystic Kidney Disease Patients. Kidney Int Rep. 2019 Dec; 4(12):1742-1748. PMID: 31844811.
      View in: PubMed
    44. Nowak KL, Chonchol M, Jovanovich A, You Z, Bates J, Foy C, Glasser S, Killeen AA, Kostis J, Rodriguez CJ, Segal M, Simmons DL, Taylor A, Lovato LC, Ambrosius WT, Supiano MA. Serum Sodium and Pulse Pressure in SPRINT. Am J Hypertens. 2019 06 11; 32(7):649-656. PMID: 30977767.
      View in: PubMed
    45. Bispham NZ, Nowak KL. Drinking Water: The Saltier The Better? J Am Heart Assoc. 2019 05 07; 8(9):e012758. PMID: 31060416.
      View in: PubMed
    46. Hung AM, Tsuchida Y, Nowak KL, Sarkar S, Chonchol M, Whitfield V, Salas N, Dikalova A, Yancey PG, Huang J, Linton MF, Ikizler TA, Kon V. IL-1 Inhibition and Function of the HDL-Containing Fraction of Plasma in Patients with Stages 3 to 5 CKD. Clin J Am Soc Nephrol. 2019 05 07; 14(5):702-711. PMID: 31015261.
      View in: PubMed
    47. Jovanovich A, You Z, Isakova T, Nowak K, Cheung A, Wolf M, Chonchol M, Kendrick J. Fibroblast Growth Factor 23 Trajectories in Chronic Hemodialysis Patients: Lessons from the HEMO Study. Am J Nephrol. 2019; 49(4):263-270. PMID: 30820005.
      View in: PubMed
    48. Nowak KL, Gitomer B, Farmer-Bailey H, Wang W, Malaczewski M, Klawitter J, You Z, George D, Patel N, Jovanovich A, Chonchol M. Mineralocorticoid Antagonism and Vascular Function in Early Autosomal Dominant Polycystic Kidney Disease: A Randomized Controlled Trial. Am J Kidney Dis. 2019 08; 74(2):213-223. PMID: 30803706.
      View in: PubMed
    49. Andrews ES, Perrenoud L, Nowak KL, You Z, Pasch A, Chonchol M, Kendrick J, Jalal D. Examining the effects of uric acid-lowering on markers vascular of calcification and CKD-MBD; A post-hoc analysis of a randomized clinical trial. PLoS One. 2018; 13(10):e0205831. PMID: 30356327.
      View in: PubMed
    50. Kendrick J, Shah P, Andrews E, You Z, Nowak K, Pasch A, Chonchol M. Effect of Treatment of Metabolic Acidosis on Vascular Endothelial Function in Patients with CKD: A Pilot Randomized Cross-Over Study. Clin J Am Soc Nephrol. 2018 10 08; 13(10):1463-1470. PMID: 30237219.
      View in: PubMed
    51. Nowak KL, Wang W, Farmer-Bailey H, Gitomer B, Malaczewski M, Klawitter J, Jovanovich A, Chonchol M. Vascular Dysfunction, Oxidative Stress, and Inflammation in Autosomal Dominant Polycystic Kidney Disease. Clin J Am Soc Nephrol. 2018 10 08; 13(10):1493-1501. PMID: 30228110.
      View in: PubMed
    52. Nowak KL, Chonchol M. Does inflammation affect outcomes in dialysis patients? Semin Dial. 2018 07; 31(4):388-397. PMID: 29513906.
      View in: PubMed
    53. Nowak KL, Chonchol M, You Z, Gupta M, Gitomer B. Affected parent sex and severity of autosomal dominant polycystic kidney disease: a retrospective cohort study?. Clin Nephrol. 2018 Mar; 89(3):196-204. PMID: 29035198.
      View in: PubMed
    54. Nowak KL, Yaffe K, Orwoll ES, Ix JH, You Z, Barrett-Connor E, Hoffman AR, Chonchol M. Serum Sodium and Cognition in Older Community-Dwelling Men. Clin J Am Soc Nephrol. 2018 03 07; 13(3):366-374. PMID: 29439092.
      View in: PubMed
    55. Nowak KL, Fried L, Jovanovich A, Ix J, Yaffe K, You Z, Chonchol M. Dietary Sodium/Potassium Intake Does Not Affect Cognitive Function or Brain Imaging Indices. Am J Nephrol. 2018; 47(1):57-65. PMID: 29393090.
      View in: PubMed
    56. Nowak KL, Rossman MJ, Chonchol M, Seals DR. Strategies for Achieving Healthy Vascular Aging. Hypertension. 2018 03; 71(3):389-402. PMID: 29311256.
      View in: PubMed
    57. Nowak KL, You Z, Gitomer B, Brosnahan G, Torres VE, Chapman AB, Perrone RD, Steinman TI, Abebe KZ, Rahbari-Oskoui FF, Yu ASL, Harris PC, Bae KT, Hogan M, Miskulin D, Chonchol M. Overweight and Obesity Are Predictors of Progression in Early Autosomal Dominant Polycystic Kidney Disease. J Am Soc Nephrol. 2018 02; 29(2):571-578. PMID: 29118087.
      View in: PubMed
    58. Nowak KL, Hung A, Ikizler TA, Farmer-Bailey H, Salas-Cruz N, Sarkar S, Hoofnagle A, You Z, Chonchol M. Interleukin-1 inhibition, chronic kidney disease-mineral and bone disorder, and physical function?. Clin Nephrol. 2017 Sep; 88(9):132-143. PMID: 28699886.
      View in: PubMed
    59. Kendrick J, Andrews E, You Z, Moreau K, Nowak KL, Farmer-Bailey H, Seals DR, Chonchol M. Cholecalciferol, Calcitriol, and Vascular Function in CKD: A Randomized, Double-Blind Trial. Clin J Am Soc Nephrol. 2017 Sep 07; 12(9):1438-1446. PMID: 28784657.
      View in: PubMed
    60. Netea MG, Balkwill F, Chonchol M, Cominelli F, Donath MY, Giamarellos-Bourboulis EJ, Golenbock D, Gresnigt MS, Heneka MT, Hoffman HM, Hotchkiss R, Joosten LAB, Kastner DL, Korte M, Latz E, Libby P, Mandrup-Poulsen T, Mantovani A, Mills KHG, Nowak KL, O'Neill LA, Pickkers P, van der Poll T, Ridker PM, Schalkwijk J, Schwartz DA, Siegmund B, Steer CJ, Tilg H, van der Meer JWM, van de Veerdonk FL, Dinarello CA. A guiding map for inflammation. Nat Immunol. 2017 Jul 19; 18(8):826-831. PMID: 28722720.
      View in: PubMed
    61. Nowak KL, Farmer H, Cadnapaphornchai MA, Gitomer B, Chonchol M. Vascular dysfunction in children and young adults with autosomal dominant polycystic kidney disease. Nephrol Dial Transplant. 2017 02 01; 32(2):342-347. PMID: 28186577.
      View in: PubMed
    62. Nowak KL, Bartz TM, Dalrymple L, de Boer IH, Kestenbaum B, Shlipak MG, Garimella PS, Ix JH, Chonchol M. Fibroblast Growth Factor 23 and the Risk of Infection-Related Hospitalization in Older Adults. J Am Soc Nephrol. 2017 Apr; 28(4):1239-1246. PMID: 28122946.
      View in: PubMed
    63. Nowak KL, Chonchol M, Ikizler TA, Farmer-Bailey H, Salas N, Chaudhry R, Wang W, Smits G, Tengesdal I, Dinarello CA, Hung AM. IL-1 Inhibition and Vascular Function in CKD. J Am Soc Nephrol. 2017 Mar; 28(3):971-980. PMID: 27647856.
      View in: PubMed
    64. Jalal DI, Decker E, Perrenoud L, Nowak KL, Bispham N, Mehta T, Smits G, You Z, Seals D, Chonchol M, Johnson RJ. Vascular Function and Uric Acid-Lowering in Stage 3 CKD. J Am Soc Nephrol. 2017 03; 28(3):943-952. PMID: 27620990.
      View in: PubMed
    65. Nowak KL, Cadnapaphornchai MA, Chonchol MB, Schrier RW, Gitomer B. Long-Term Outcomes in Patients with Very-Early Onset Autosomal Dominant Polycystic Kidney Disease. Am J Nephrol. 2016; 44(3):171-8. PMID: 27548646.
      View in: PubMed
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    67. Jablonski KL, Donato AJ, Fleenor BS, Nowlan MJ, Walker AE, Kaplon RE, Ballak DB, Seals DR. Reduced large elastic artery stiffness with regular aerobic exercise in middle-aged and older adults: potential role of suppressed nuclear factor ? B signalling. J Hypertens. 2015 Dec; 33(12):2477-82. PMID: 26378681.
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    69. Jablonski KL, Chonchol M. Posthemodialysis weights and mortality: another narrow range target? Clin J Am Soc Nephrol. 2015 May 07; 10(5):729-31. PMID: 25862780.
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    74. Miyazaki-Anzai S, Masuda M, Demos-Davies KM, Keenan AL, Saunders SJ, Masuda R, Jablonski K, Cavasin MA, Kendrick J, Chonchol M, McKinsey TA, Levi M, Miyazaki M. Endoplasmic reticulum stress effector CCAAT/enhancer-binding protein homologous protein (CHOP) regulates chronic kidney disease-induced vascular calcification. J Am Heart Assoc. 2014 Jun 24; 3(3):e000949. PMID: 24963104.
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    77. Jablonski KL, Chonchol M. Vascular calcification in end-stage renal disease. Hemodial Int. 2013 Oct; 17 Suppl 1:S17-21. PMID: 24134325.
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    78. Jablonski KL, Fedorova OV, Racine ML, Geolfos CJ, Gates PE, Chonchol M, Fleenor BS, Lakatta EG, Bagrov AY, Seals DR. Dietary sodium restriction and association with urinary marinobufagenin, blood pressure, and aortic stiffness. Clin J Am Soc Nephrol. 2013 Nov; 8(11):1952-9. PMID: 23929930.
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    79. Jablonski KL, Chonchol M. Chronic kidney disease: Cystatin-C-based eGFR: what is it telling us? Nat Rev Nephrol. 2013 Jun; 9(6):318-9. PMID: 23591444.
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    80. DeVan AE, Eskurza I, Pierce GL, Walker AE, Jablonski KL, Kaplon RE, Seals DR. Regular aerobic exercise protects against impaired fasting plasma glucose-associated vascular endothelial dysfunction with aging. Clin Sci (Lond). 2013 Mar; 124(5):325-31. PMID: 23025811.
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    81. Jablonski KL, Racine ML, Geolfos CJ, Gates PE, Chonchol M, McQueen MB, Seals DR. Dietary sodium restriction reverses vascular endothelial dysfunction in middle-aged/older adults with moderately elevated systolic blood pressure. J Am Coll Cardiol. 2013 Jan 22; 61(3):335-43. PMID: 23141486.
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    82. Jablonski KL, Chonchol M. Cardiovascular disease: Should statin therapy be expanded in patients with CKD? Nat Rev Nephrol. 2012 Jul 03; 8(8):440-1. PMID: 22751508.
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    83. Pierce GL, Jablonski KL, Walker AE, Seibert SM, DeVan AE, Black SM, Sharma S, Seals DR. Tetrahydrobiopterin supplementation enhances carotid artery compliance in healthy older men: a pilot study. Am J Hypertens. 2012 Oct; 25(10):1050-4. PMID: 22673017.
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    84. Jablonski KL, Chonchol M. Frequent hemodialysis: a way to improve physical function? Clin J Am Soc Nephrol. 2012 May; 7(5):707-10. PMID: 22516284.
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    85. Jalal DI, Jablonski KL, McFann K, Chonchol MB, Seals DR. Vascular endothelial function is not related to serum uric acid in healthy adults. Am J Hypertens. 2012 Apr; 25(4):407-13. PMID: 22237152.
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    86. Seals DR, Jablonski KL, Donato AJ. Aging and vascular endothelial function in humans. Clin Sci (Lond). 2011 May; 120(9):357-75. PMID: 21244363.
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    87. Jablonski KL, Chonchol M, Pierce GL, Walker AE, Seals DR. 25-Hydroxyvitamin D deficiency is associated with inflammation-linked vascular endothelial dysfunction in middle-aged and older adults. Hypertension. 2011 Jan; 57(1):63-9. PMID: 21115878.
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    88. Jablonski KL, Gates PE, Pierce GL, Seals DR. Low dietary sodium intake is associated with enhanced vascular endothelial function in middle-aged and older adults with elevated systolic blood pressure. Ther Adv Cardiovasc Dis. 2009 Oct; 3(5):347-56. PMID: 19723834.
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    89. Donato AJ, Gano LB, Eskurza I, Silver AE, Gates PE, Jablonski K, Seals DR. Vascular endothelial dysfunction with aging: endothelin-1 and endothelial nitric oxide synthase. Am J Physiol Heart Circ Physiol. 2009 Jul; 297(1):H425-32. PMID: 19465546.
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    90. Donato AJ, Black AD, Jablonski KL, Gano LB, Seals DR. Aging is associated with greater nuclear NF kappa B, reduced I kappa B alpha, and increased expression of proinflammatory cytokines in vascular endothelial cells of healthy humans. Aging Cell. 2008 Dec; 7(6):805-12. PMID: 18782346.
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    91. Donato AJ, Eskurza I, Jablonski KL, Gano LB, Pierce GL, Seals DR. Cytochrome P-450 2C9 signaling does not contribute to age-associated vascular endothelial dysfunction in humans. J Appl Physiol (1985). 2008 Oct; 105(4):1359-63. PMID: 18669935.
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    92. Jablonski KL, Seals DR, Eskurza I, Monahan KD, Donato AJ. High-dose ascorbic acid infusion abolishes chronic vasoconstriction and restores resting leg blood flow in healthy older men. J Appl Physiol (1985). 2007 Nov; 103(5):1715-21. PMID: 17965239.
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