Colorado PROFILES, The Colorado Clinical and Translational Sciences Institute (CCTSI)
Keywords
Last Name
Institution

Contact Us
If you have any questions or feedback please contact us.

Ryan Karn Bachtell

TitleAssociate Professor
InstitutionUniversity of Colorado Boulder
DepartmentPsych-Psychology
Phone303/735-1012

    Collapse Research 
    Collapse research activities and funding
    F31AA013223     (BACHTELL, RYAN K.)Jun 22, 2001
    NIH/NIAAA
    Characterizing the Edinger-Westphal response to alcohol
    Role: Principal Investigator

    F32DA018481     (BACHTELL, RYAN K.)Sep 1, 2004 - Aug 31, 2007
    NIH/NIDA
    Dopamine receptor interactions with GluR1 in addiction
    Role: Principal Investigator

    R03DA029240     (BACHTELL, RYAN K.)Mar 15, 2011 - Feb 28, 2013
    NIH/NIDA
    Effects of Adenosine Signaling on Cocaine Reward and Relapse
    Role: Principal Investigator

    R01DA033358     (BACHTELL, RYAN K.)Jan 1, 2013 - Dec 31, 2017
    NIH/NIDA
    Adenosine Receptor Involvement in Methamphetamine Reward and Relapse
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    List All   |   Timeline
    1. Bachtell RK, Jones JD, Heinzerling KG, Beardsley PM, Comer SD. Glial and neuroinflammatory targets for treating substance use disorders. Drug Alcohol Depend. 2017 Nov 01; 180:156-170. PMID: 28892721.
      View in: PubMed
    2. Brown KT, Levis SC, O'Neill CE, Northcutt AL, Fabisiak TJ, Watkins LR, Bachtell RK. Innate immune signaling in the ventral tegmental area contributes to drug-primed reinstatement of cocaine seeking. Brain Behav Immun. 2017 Aug 13. PMID: 28813640.
      View in: PubMed
    3. Winkler MC, Greager EM, Stafford J, Bachtell RK. Methamphetamine self-administration reduces alcohol consumption and preference in alcohol-preferring P rats. Addict Biol. 2016 Nov 16. PMID: 27860181.
      View in: PubMed
    4. Klipec WD, Burrow KR, O'Neill C, Cao JL, Lawyer CR, Ostertag E, Fowler M, Bachtell RK, Illig KR, Cooper DC. Loss of the trpc4 gene is associated with a reduction in cocaine self-administration and reduced spontaneous ventral tegmental area dopamine neuronal activity, without deficits in learning for natural rewards. Behav Brain Res. 2016 Jun 01; 306:117-27. PMID: 26988269.
      View in: PubMed
    5. O'Neill CE, Newsom RJ, Stafford J, Scott T, Archuleta S, Levis SC, Spencer RL, Campeau S, Bachtell RK. Adolescent caffeine consumption increases adulthood anxiety-related behavior and modifies neuroendocrine signaling. Psychoneuroendocrinology. 2016 May; 67:40-50. PMID: 26874560; PMCID: PMC4808446 [Available on 05/01/17].
    6. Northcutt AL, Hutchinson MR, Wang X, Baratta MV, Hiranita T, Cochran TA, Pomrenze MB, Galer EL, Kopajtic TA, Li CM, Amat J, Larson G, Cooper DC, Huang Y, O'Neill CE, Yin H, Zahniser NR, Katz JL, Rice KC, Maier SF, Bachtell RK, Watkins LR. DAT isn't all that: cocaine reward and reinforcement require Toll-like receptor 4 signaling. Mol Psychiatry. 2015 Dec; 20(12):1525-37. PMID: 25644383; PMCID: PMC4523496.
    7. Bachtell R, Hutchinson MR, Wang X, Rice KC, Maier SF, Watkins LR. Targeting the Toll of Drug Abuse: The Translational Potential of Toll-Like Receptor 4. CNS Neurol Disord Drug Targets. 2015; 14(6):692-9. PMID: 26022268.
      View in: PubMed
    8. O'Neill CE, Levis SC, Schreiner DC, Amat J, Maier SF, Bachtell RK. Effects of adolescent caffeine consumption on cocaine sensitivity. Neuropsychopharmacology. 2015 Mar; 40(4):813-21. PMID: 25328052; PMCID: PMC4330515.
    9. Kavanagh KA, Schreiner DC, Levis SC, O'Neill CE, Bachtell RK. Role of adenosine receptor subtypes in methamphetamine reward and reinforcement. Neuropharmacology. 2015 Feb; 89:265-73. PMID: 25301277; PMCID: PMC4250385.
    10. O'Neill CE, Hobson BD, Levis SC, Bachtell RK. Persistent reduction of cocaine seeking by pharmacological manipulation of adenosine A1 and A 2A receptors during extinction training in rats. Psychopharmacology (Berl). 2014 Aug; 231(16):3179-88. PMID: 24562064; PMCID: PMC4111968.
    11. Merritt KE, Bachtell RK. Initial d2 dopamine receptor sensitivity predicts cocaine sensitivity and reward in rats. PLoS One. 2013; 8(11):e78258. PMID: 24223783; PMCID: PMC3817276.
    12. Hobson BD, O'Neill CE, Levis SC, Monteggia LM, Neve RL, Self DW, Bachtell RK. Adenosine A1 and dopamine d1 receptor regulation of AMPA receptor phosphorylation and cocaine-seeking behavior. Neuropsychopharmacology. 2013 Sep; 38(10):1974-83. PMID: 23598433; PMCID: PMC3746705.
    13. Rasmus KC, O'Neill CE, Bachtell RK, Cooper DC. Cocaine self-administration in rats lacking a functional trpc4 gene. F1000Res. 2013; 2:110. PMID: 24555056; PMCID: PMC3901450.
    14. Hutchinson MR, Northcutt AL, Hiranita T, Wang X, Lewis SS, Thomas J, van Steeg K, Kopajtic TA, Loram LC, Sfregola C, Galer E, Miles NE, Bland ST, Amat J, Rozeske RR, Maslanik T, Chapman TR, Strand KA, Fleshner M, Bachtell RK, Somogyi AA, Yin H, Katz JL, Rice KC, Maier SF, Watkins LR. Opioid activation of toll-like receptor 4 contributes to drug reinforcement. J Neurosci. 2012 Aug 15; 32(33):11187-200. PMID: 22895704; PMCID: PMC3454463.
    15. Hobson BD, Merritt KE, Bachtell RK. Stimulation of adenosine receptors in the nucleus accumbens reverses the expression of cocaine sensitization and cross-sensitization to dopamine D2 receptors in rats. Neuropharmacology. 2012 Nov; 63(6):1172-81. PMID: 22749927; PMCID: PMC3427408.
    16. O'Neill CE, LeTendre ML, Bachtell RK. Adenosine A2A receptors in the nucleus accumbens bi-directionally alter cocaine seeking in rats. Neuropsychopharmacology. 2012 Apr; 37(5):1245-56. PMID: 22169945; PMCID: PMC3306886.
    17. Edwards S, Bachtell RK, Guzman D, Whisler KN, Self DW. Emergence of context-associated GluR(1) and ERK phosphorylation in the nucleus accumbens core during withdrawal from cocaine self-administration. Addict Biol. 2011 Jul; 16(3):450-7. PMID: 21309958; PMCID: PMC3115519.
    18. Cadle BA, Rasmus KC, Varela JA, Leverich LS, O'Neill CE, Bachtell RK, Cooper DC. Cellular phone-based image acquisition and quantitative ratiometric method for detecting cocaine and benzoylecgonine for biological and forensic applications. Subst Abuse. 2010; 4:21-33. PMID: 22879741; PMCID: PMC3411535.
    19. Bachtell RK, Self DW. Effects of adenosine A2A receptor stimulation on cocaine-seeking behavior in rats. Psychopharmacology (Berl). 2009 Oct; 206(3):469-78. PMID: 19641899; PMCID: PMC2759773.
    20. Bachtell RK, Self DW. Renewed cocaine exposure produces transient alterations in nucleus accumbens AMPA receptor-mediated behavior. J Neurosci. 2008 Nov 26; 28(48):12808-14. PMID: 19036973; PMCID: PMC2615571.
    21. Graham DL, Krishnan V, Larson EB, Graham A, Edwards S, Bachtell RK, Simmons D, Gent LM, Berton O, Bolanos CA, DiLeone RJ, Parada LF, Nestler EJ, Self DW. Tropomyosin-related kinase B in the mesolimbic dopamine system: region-specific effects on cocaine reward. Biol Psychiatry. 2009 Apr 15; 65(8):696-701. PMID: 18990365; PMCID: PMC2738869.
    22. Winstanley CA, Bachtell RK, Theobald DE, Laali S, Green TA, Kumar A, Chakravarty S, Self DW, Nestler EJ. Increased impulsivity during withdrawal from cocaine self-administration: role for DeltaFosB in the orbitofrontal cortex. Cereb Cortex. 2009 Feb; 19(2):435-44. PMID: 18539927; PMCID: PMC2733325.
    23. Perrotti LI, Weaver RR, Robison B, Renthal W, Maze I, Yazdani S, Elmore RG, Knapp DJ, Selley DE, Martin BR, Sim-Selley L, Bachtell RK, Self DW, Nestler EJ. Distinct patterns of DeltaFosB induction in brain by drugs of abuse. Synapse. 2008 May; 62(5):358-69. PMID: 18293355; PMCID: PMC2667282.
    24. Bachtell RK, Choi KH, Simmons DL, Falcon E, Monteggia LM, Neve RL, Self DW. Role of GluR1 expression in nucleus accumbens neurons in cocaine sensitization and cocaine-seeking behavior. Eur J Neurosci. 2008 May; 27(9):2229-40. PMID: 18430032.
      View in: PubMed
    25. Winstanley CA, LaPlant Q, Theobald DE, Green TA, Bachtell RK, Perrotti LI, DiLeone RJ, Russo SJ, Garth WJ, Self DW, Nestler EJ. DeltaFosB induction in orbitofrontal cortex mediates tolerance to cocaine-induced cognitive dysfunction. J Neurosci. 2007 Sep 26; 27(39):10497-507. PMID: 17898221.
      View in: PubMed
    26. Graham DL, Edwards S, Bachtell RK, DiLeone RJ, Rios M, Self DW. Dynamic BDNF activity in nucleus accumbens with cocaine use increases self-administration and relapse. Nat Neurosci. 2007 Aug; 10(8):1029-37. PMID: 17618281.
      View in: PubMed
    27. Edwards S, Graham DL, Bachtell RK, Self DW. Region-specific tolerance to cocaine-regulated cAMP-dependent protein phosphorylation following chronic self-administration. Eur J Neurosci. 2007 Apr; 25(7):2201-13. PMID: 17439498.
      View in: PubMed
    28. Bachtell RK, Whisler K, Karanian D, Self DW. Effects of intra-nucleus accumbens shell administration of dopamine agonists and antagonists on cocaine-taking and cocaine-seeking behaviors in the rat. Psychopharmacology (Berl). 2005 Nov; 183(1):41-53. PMID: 16163523.
      View in: PubMed
    29. Bachtell RK, Weitemier AZ, Ryabinin AE. Lesions of the Edinger-Westphal nucleus in C57BL/6J mice disrupt ethanol-induced hypothermia and ethanol consumption. Eur J Neurosci. 2004 Sep; 20(6):1613-23. PMID: 15355328.
      View in: PubMed
    30. Bachtell RK, Weitemier AZ, Galvan-Rosas A, Tsivkovskaia NO, Risinger FO, Phillips TJ, Grahame NJ, Ryabinin AE. The Edinger-Westphal-lateral septum urocortin pathway and its relationship to alcohol consumption. J Neurosci. 2003 Mar 15; 23(6):2477-87. PMID: 12657708.
      View in: PubMed
    31. Kiianmaa K, Hyytiä P, Samson HH, Engel JA, Svensson L, Söderpalm B, Larsson A, Colombo G, Vacca G, Finn DA, Bachtell RK, Ryabinin AE. New neuronal networks involved in ethanol reinforcement. Alcohol Clin Exp Res. 2003 Feb; 27(2):209-19. PMID: 12605070.
      View in: PubMed
    32. Bachtell RK, Tsivkovskaia NO, Ryabinin AE. Identification of temperature-sensitive neural circuits in mice using c-Fos expression mapping. Brain Res. 2003 Jan 17; 960(1-2):157-64. PMID: 12505668.
      View in: PubMed
    33. Ryabinin AE, Galvan-Rosas A, Bachtell RK, Risinger FO. High alcohol/sucrose consumption during dark circadian phase in C57BL/6J mice: involvement of hippocampus, lateral septum and urocortin-positive cells of the Edinger-Westphal nucleus. Psychopharmacology (Berl). 2003 Jan; 165(3):296-305. PMID: 12442202.
      View in: PubMed
    34. Bachtell RK, Tsivkovskaia NO, Ryabinin AE. Alcohol-induced c-Fos expression in the Edinger-Westphal nucleus: pharmacological and signal transduction mechanisms. J Pharmacol Exp Ther. 2002 Aug; 302(2):516-24. PMID: 12130710.
      View in: PubMed
    35. Ryabinin AE, Bachtell RK, Heinrichs SC, Lee S, Rivier C, Olive MF, Mehmert KK, Camarini R, Kim JA, Koenig HN, Nannini MA, Hodge CW, Roberts AJ, Koob GF. The corticotropin-releasing factor/urocortin system and alcohol. Alcohol Clin Exp Res. 2002 May; 26(5):714-22. PMID: 12045481.
      View in: PubMed
    36. Bachtell RK, Tsivkovskaia NO, Ryabinin AE. Strain differences in urocortin expression in the Edinger-Westphal nucleus and its relation to alcohol-induced hypothermia. Neuroscience. 2002; 113(2):421-34. PMID: 12127099.
      View in: PubMed
    37. Ryabinin AE, Bachtell RK, Freeman P, Risinger FO. ITF expression in mouse brain during acquisition of alcohol self-administration. Brain Res. 2001 Jan 26; 890(1):192-5. PMID: 11164784.
      View in: PubMed
    38. Bachtell RK, Ryabinin AE. Interactive effects of nicotine and alcohol co-administration on expression of inducible transcription factors in mouse brain. Neuroscience. 2001; 103(4):941-54. PMID: 11301203.
      View in: PubMed
    39. Ryabinin AE, Wang YM, Bachtell RK, Kinney AE, Grubb MC, Mark GP. Cocaine- and alcohol-mediated expression of inducible transcription factors is blocked by pentobarbital anesthesia. Brain Res. 2000 Sep 22; 877(2):251-61. PMID: 10986339.
      View in: PubMed
    40. Bachtell RK, Wang YM, Freeman P, Risinger FO, Ryabinin AE. Alcohol drinking produces brain region-selective changes in expression of inducible transcription factors. Brain Res. 1999 Nov 20; 847(2):157-65. PMID: 10575084.
      View in: PubMed
    Bachtell's Networks
    Click the "See All" links for more information and interactive visualizations!
    Concepts Expand Description
    _
    Co-Authors Expand Description
    _
    Similar People Expand Description
    _
    Same Department Expand Description
    Physical Neighbors Expand Description
    _

    Copyright © 2017 The Regents of the University of Colorado, a body corporate. All rights reserved. (Harvard PROFILES RNS software version: 2.10.0)