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Michael J. Schurr

TitleAssociate Professor
InstitutionUniversity of Colorado Denver - Anschutz Medical Campus
DepartmentSOM-Immunology Microbiology
Phone303 7244221

    Collapse Research 
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    R01AI050812     (SCHURR, MICHAEL JOHN)Feb 1, 2004 - Jan 31, 2010
    Regulation of Ps. aeruginosa Virulence Factors by AlgR
    Role: Principal Investigator

    R21AI094487     (SCHURR, MICHAEL JOHN)Apr 1, 2012 - Mar 31, 2014
    Control of Pseudomonas aeruginosa Quorum Sensing and Alginate
    Role: Principal Investigator

    SCHURR1610     (Michael J. Schurr)Apr 1, 2017 - Sep 1, 2018
    Cystic Fibrosis Foundation
    Iron Acquisition of Mucoid Pseudomonas aeruginosa
    Role Description: Pseudomonas aeruginosa is a ubiquitous, opportunistic pathogen infecting individuals with cystic fibrosis (CF). Due to the uncanny antibiotic resistance, CF patients infected with Pseudomonas often have chronic infections with limited therapeutic options. Part of the ability to resist antibiotic treatment and clearance by the immune system is due to the ability of the organism to grow in a community termed a biofilm. A basic understanding of the pathogenic mechanisms utilized by this organism in a bioflm is needed for possible therapeutic targets. P. aeruginosa produces alginate, rhamnolipids, type IV pili and cyanide under biofilm growth conditions and all of these are controlled by a protein that regulates transcription, AlgR. Iron acquisition is also an important part of establishing and maintaining P. aeruginosa biofilms. In fact, alginate production increases as iron levels decrease. We have recently determined that AlgR phosphorylation controls iron acquisition molecules, termed siderophores. Moreover, we have also determined that AlgR phosphorylation is required in a murine acute pneumonia model. Our preliminary evidence also shows that these multiple phenotypes (twitching motility, alginate and siderophore production) are both oxygen- and AlgR-dependent. Together, these data indicate that the protein that phosphorylates AlgR, AlgZ/FimS, responds to oxygen, phosphorylates AlgR and activates iron acquisition molecules. Therapeutic inhibition of the AlgZR two-component system would shut down alginate production, twitching motility, and iron acquisition. The goals of this research are to determine how AlgZ senses oxygen and to determine which genes are specifically activated by AlgR to control iron acquisition.
    Role: Principle Investigator

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    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Little AS, Okkotsu Y, Reinhart AA, Damron FH, Barbier M, Barrett B, Oglesby-Sherrouse AG, Goldberg JB, Cody WL, Schurr MJ, Vasil ML, Schurr MJ. Pseudomonas aeruginosa AlgR Phosphorylation Status Differentially Regulates Pyocyanin and Pyoverdine Production. MBio. 2018 01 30; 9(1). PMID: 29382736.
      View in: PubMed
    2. Heacock-Kang Y, Sun Z, Zarzycki-Siek J, McMillan IA, Norris MH, Bluhm AP, Cabanas D, Fogen D, Vo H, Donachie SP, Borlee BR, Sibley CD, Lewenza S, Schurr MJ, Schweizer HP, Hoang TT. Spatial transcriptomes within the Pseudomonas aeruginosa biofilm architecture. Mol Microbiol. 2017 Dec; 106(6):976-985. PMID: 29030956.
      View in: PubMed
    3. Bartek IL, Reichlen MJ, Honaker RW, Leistikow RL, Clambey ET, Scobey MS, Hinds AB, Born SE, Covey CR, Schurr MJ, Lenaerts AJ, Voskuil MI. Antibiotic Bactericidal Activity Is Countered by Maintaining pH Homeostasis in Mycobacterium smegmatis. mSphere. 2016 Jul-Aug; 1(4). PMID: 27579369; PMCID: PMC4999920.
    4. Grover N, Plaks JG, Summers SR, Chado GR, Schurr MJ, Kaar JL. Acylase-containing polyurethane coatings with anti-biofilm activity. Biotechnol Bioeng. 2016 12; 113(12):2535-2543. PMID: 27240552.
      View in: PubMed
    5. Brandenburg KS, Calderon DF, Kierski PR, Brown AL, Shah NM, Abbott NL, Schurr MJ, Murphy CJ, McAnulty JF, Czuprynski CJ. Inhibition of Pseudomonas aeruginosa biofilm formation on wound dressings. Wound Repair Regen. 2015 Nov-Dec; 23(6):842-54. PMID: 26342168; PMCID: PMC4980578.
    6. Pritchett CL, Little AS, Okkotsu Y, Frisk A, Cody WL, Covey CR, Schurr MJ. Expression analysis of the Pseudomonas aeruginosa AlgZR two-component regulatory system. J Bacteriol. 2015 Feb 15; 197(4):736-48. PMID: 25488298; PMCID: PMC4334192.
    7. Okkotsu Y, Little AS, Schurr MJ. The Pseudomonas aeruginosa AlgZR two-component system coordinates multiple phenotypes. Front Cell Infect Microbiol. 2014; 4:82. PMID: 24999454; PMCID: PMC4064291.
    8. Su S, Panmanee W, Wilson JJ, Mahtani HK, Li Q, Vanderwielen BD, Makris TM, Rogers M, McDaniel C, Lipscomb JD, Irvin RT, Schurr MJ, Lancaster JR, Kovall RA, Hassett DJ. Catalase (KatA) plays a role in protection against anaerobic nitric oxide in Pseudomonas aeruginosa. PLoS One. 2014; 9(3):e91813. PMID: 24663218; PMCID: PMC3963858.
    9. Chambers JR, Liao J, Schurr MJ, Sauer K. BrlR from Pseudomonas aeruginosa is a c-di-GMP-responsive transcription factor. Mol Microbiol. 2014 May; 92(3):471-87. PMID: 24612375; PMCID: PMC4000578.
    10. Herron M, Agarwal A, Kierski PR, Calderon DF, Teixeira LB, Schurr MJ, Murphy CJ, Czuprynski CJ, McAnulty JF, Abbott NL. Reduction in wound bioburden using a silver-loaded dissolvable microfilm construct. Adv Healthc Mater. 2014 Jun; 3(6):916-28. PMID: 24523027; PMCID: PMC4112187.
    11. Wiens JR, Vasil AI, Schurr MJ, Vasil ML. Iron-regulated expression of alginate production, mucoid phenotype, and biofilm formation by Pseudomonas aeruginosa. MBio. 2014 Feb 04; 5(1):e01010-13. PMID: 24496793; PMCID: PMC3950519.
    12. Price TP, Ivashchenko A, Schurr MJ. Perioperative visual loss after excision and autografting of a thermal burn to the back. Burns. 2014 Jun; 40(4):e31-4. PMID: 24468506.
      View in: PubMed
    13. Guthrie KM, Agarwal A, Teixeira LB, Dubielzig RR, Abbott NL, Murphy CJ, Singh H, McAnulty JF, Schurr MJ. Integration of silver nanoparticle-impregnated polyelectrolyte multilayers into murine-splinted cutaneous wound beds. J Burn Care Res. 2013 Nov-Dec; 34(6):e359-67. PMID: 23511285.
      View in: PubMed
    14. Yin Y, Damron FH, Withers TR, Pritchett CL, Wang X, Schurr MJ, Yu HD. Expression of mucoid induction factor MucE is dependent upon the alternate sigma factor AlgU in Pseudomonas aeruginosa. BMC Microbiol. 2013 Oct 18; 13:232. PMID: 24138584; PMCID: PMC3819740.
    15. Okkotsu Y, Tieku P, Fitzsimmons LF, Churchill ME, Schurr MJ. Pseudomonas aeruginosa AlgR phosphorylation modulates rhamnolipid production and motility. J Bacteriol. 2013 Dec; 195(24):5499-515. PMID: 24097945; PMCID: PMC3889618.
    16. Damron FH, Barbier M, McKenney ES, Schurr MJ, Goldberg JB. Genes required for and effects of alginate overproduction induced by growth of Pseudomonas aeruginosa on Pseudomonas isolation agar supplemented with ammonium metavanadate. J Bacteriol. 2013 Sep; 195(18):4020-36. PMID: 23794622; PMCID: PMC3754734.
    17. Liao J, Schurr MJ, Sauer K. The MerR-like regulator BrlR confers biofilm tolerance by activating multidrug efflux pumps in Pseudomonas aeruginosa biofilms. J Bacteriol. 2013 Aug; 195(15):3352-63. PMID: 23687276; PMCID: PMC3719540.
    18. Schurr MJ. Which bacterial biofilm exopolysaccharide is preferred, Psl or alginate? J Bacteriol. 2013 Apr; 195(8):1623-6. PMID: 23417492; PMCID: PMC3624548.
    19. Brandenburg KS, Rodriguez KJ, McAnulty JF, Murphy CJ, Abbott NL, Schurr MJ, Czuprynski CJ. Tryptophan inhibits biofilm formation by Pseudomonas aeruginosa. Antimicrob Agents Chemother. 2013 Apr; 57(4):1921-5. PMID: 23318791; PMCID: PMC3623306.
    20. Petrova OE, Schurr JR, Schurr MJ, Sauer K. Microcolony formation by the opportunistic pathogen Pseudomonas aeruginosa requires pyruvate and pyruvate fermentation. Mol Microbiol. 2012 Nov; 86(4):819-35. PMID: 22931250; PMCID: PMC3527662.
    21. Damron FH, Owings JP, Okkotsu Y, Varga JJ, Schurr JR, Goldberg JB, Schurr MJ, Yu HD. Analysis of the Pseudomonas aeruginosa regulon controlled by the sensor kinase KinB and sigma factor RpoN. J Bacteriol. 2012 Mar; 194(6):1317-30. PMID: 22210761.
      View in: PubMed
    22. Petrova OE, Schurr JR, Schurr MJ, Sauer K. The novel Pseudomonas aeruginosa two-component regulator BfmR controls bacteriophage-mediated lysis and DNA release during biofilm development through PhdA. Mol Microbiol. 2011 Aug; 81(3):767-83. PMID: 21696457; PMCID: PMC3214647.
    23. Kuang Z, Hao Y, Hwang S, Zhang S, Kim E, Akinbi HT, Schurr MJ, Irvin RT, Hassett DJ, Lau GW. The Pseudomonas aeruginosa flagellum confers resistance to pulmonary surfactant protein-A by impacting the production of exoproteases through quorum-sensing. Mol Microbiol. 2011 Mar; 79(5):1220-35. PMID: 21205009; PMCID: PMC3043146.
    24. Crabbé A, Schurr MJ, Monsieurs P, Morici L, Schurr J, Wilson JW, Ott CM, Tsaprailis G, Pierson DL, Stefanyshyn-Piper H, Nickerson CA. Transcriptional and proteomic responses of Pseudomonas aeruginosa PAO1 to spaceflight conditions involve Hfq regulation and reveal a role for oxygen. Appl Environ Microbiol. 2011 Feb; 77(4):1221-30. PMID: 21169425; PMCID: PMC3067220.
    25. Jones AK, Fulcher NB, Balzer GJ, Urbanowski ML, Pritchett CL, Schurr MJ, Yahr TL, Wolfgang MC. Activation of the Pseudomonas aeruginosa AlgU regulon through mucA mutation inhibits cyclic AMP/Vfr signaling. J Bacteriol. 2010 Nov; 192(21):5709-17. PMID: 20817772; PMCID: PMC2953679.
    26. Hassett DJ, Korfhagen TR, Irvin RT, Schurr MJ, Sauer K, Lau GW, Sutton MD, Yu H, Hoiby N. Pseudomonas aeruginosa biofilm infections in cystic fibrosis: insights into pathogenic processes and treatment strategies. Expert Opin Ther Targets. 2010 Feb; 14(2):117-30. PMID: 20055712.
      View in: PubMed
    27. Kang Y, Lunin VV, Skarina T, Savchenko A, Schurr MJ, Hoang TT. The long-chain fatty acid sensor, PsrA, modulates the expression of rpoS and the type III secretion exsCEBA operon in Pseudomonas aeruginosa. Mol Microbiol. 2009 Jul; 73(1):120-36. PMID: 19508282; PMCID: PMC2759274.
    28. Cody WL, Pritchett CL, Jones AK, Carterson AJ, Jackson D, Frisk A, Wolfgang MC, Schurr MJ. Pseudomonas aeruginosa AlgR controls cyanide production in an AlgZ-dependent manner. J Bacteriol. 2009 May; 191(9):2993-3002. PMID: 19270096; PMCID: PMC2681793.
    29. Hassett DJ, Sutton MD, Schurr MJ, Herr AB, Caldwell CC, Matu JO. Pseudomonas aeruginosa hypoxic or anaerobic biofilm infections within cystic fibrosis airways. Trends Microbiol. 2009 Mar; 17(3):130-8. PMID: 19231190.
      View in: PubMed
    30. Wilson JW, Ott CM, Quick L, Davis R, Höner zu Bentrup K, Crabbé A, Richter E, Sarker S, Barrila J, Porwollik S, Cheng P, McClelland M, Tsaprailis G, Radabaugh T, Hunt A, Shah M, Nelman-Gonzalez M, Hing S, Parra M, Dumars P, Norwood K, Bober R, Devich J, Ruggles A, CdeBaca A, Narayan S, Benjamin J, Goulart C, Rupert M, Catella L, Schurr MJ, Buchanan K, Morici L, McCracken J, Porter MD, Pierson DL, Smith SM, Mergeay M, Leys N, Stefanyshyn-Piper HM, Gorie D, Nickerson CA. Media ion composition controls regulatory and virulence response of Salmonella in spaceflight. PLoS One. 2008; 3(12):e3923. PMID: 19079590; PMCID: PMC2592540.
    31. Cody WL, Wilson JW, Hendrixson DR, McIver KS, Hagman KE, Ott CM, Nickerson CA, Schurr MJ. Skim milk enhances the preservation of thawed -80 degrees C bacterial stocks. J Microbiol Methods. 2008 Sep; 75(1):135-8. PMID: 18573555; PMCID: PMC2551311.
    32. Platt MD, Schurr MJ, Sauer K, Vazquez G, Kukavica-Ibrulj I, Potvin E, Levesque RC, Fedynak A, Brinkman FS, Schurr J, Hwang SH, Lau GW, Limbach PA, Rowe JJ, Lieberman MA, Barraud N, Webb J, Kjelleberg S, Hunt DF, Hassett DJ. Proteomic, microarray, and signature-tagged mutagenesis analyses of anaerobic Pseudomonas aeruginosa at pH 6.5, likely representing chronic, late-stage cystic fibrosis airway conditions. J Bacteriol. 2008 Apr; 190(8):2739-58. PMID: 18203836; PMCID: PMC2293228.
    33. Wilson JW, Ott CM, Höner zu Bentrup K, Ramamurthy R, Quick L, Porwollik S, Cheng P, McClelland M, Tsaprailis G, Radabaugh T, Hunt A, Fernandez D, Richter E, Shah M, Kilcoyne M, Joshi L, Nelman-Gonzalez M, Hing S, Parra M, Dumars P, Norwood K, Bober R, Devich J, Ruggles A, Goulart C, Rupert M, Stodieck L, Stafford P, Catella L, Schurr MJ, Buchanan K, Morici L, McCracken J, Allen P, Baker-Coleman C, Hammond T, Vogel J, Nelson R, Pierson DL, Stefanyshyn-Piper HM, Nickerson CA. Space flight alters bacterial gene expression and virulence and reveals a role for global regulator Hfq. Proc Natl Acad Sci U S A. 2007 Oct 09; 104(41):16299-304. PMID: 17901201; PMCID: PMC2042201.
    34. Morici LA, Carterson AJ, Wagner VE, Frisk A, Schurr JR, Höner zu Bentrup K, Hassett DJ, Iglewski BH, Sauer K, Schurr MJ. Pseudomonas aeruginosa AlgR represses the Rhl quorum-sensing system in a biofilm-specific manner. J Bacteriol. 2007 Nov; 189(21):7752-64. PMID: 17766417; PMCID: PMC2168728.
    35. Yoon SS, Karabulut AC, Lipscomb JD, Hennigan RF, Lymar SV, Groce SL, Herr AB, Howell ML, Kiley PJ, Schurr MJ, Gaston B, Choi KH, Schweizer HP, Hassett DJ. Two-pronged survival strategy for the major cystic fibrosis pathogen, Pseudomonas aeruginosa, lacking the capacity to degrade nitric oxide during anaerobic respiration. EMBO J. 2007 Aug 08; 26(15):3662-72. PMID: 17627281; PMCID: PMC1949006.
    36. Yoon SS, Coakley R, Lau GW, Lymar SV, Gaston B, Karabulut AC, Hennigan RF, Hwang SH, Buettner G, Schurr MJ, Mortensen JE, Burns JL, Speert D, Boucher RC, Hassett DJ. Anaerobic killing of mucoid Pseudomonas aeruginosa by acidified nitrite derivatives under cystic fibrosis airway conditions. J Clin Invest. 2006 Feb; 116(2):436-46. PMID: 16440061; PMCID: PMC1350997.
    37. Carterson AJ, Höner zu Bentrup K, Ott CM, Clarke MS, Pierson DL, Vanderburg CR, Buchanan KL, Nickerson CA, Schurr MJ. A549 lung epithelial cells grown as three-dimensional aggregates: alternative tissue culture model for Pseudomonas aeruginosa pathogenesis. Infect Immun. 2005 Feb; 73(2):1129-40. PMID: 15664956; PMCID: PMC547019.
    38. Carterson AJ, Morici LA, Jackson DW, Frisk A, Lizewski SE, Jupiter R, Simpson K, Kunz DA, Davis SH, Schurr JR, Hassett DJ, Schurr MJ. The transcriptional regulator AlgR controls cyanide production in Pseudomonas aeruginosa. J Bacteriol. 2004 Oct; 186(20):6837-44. PMID: 15466037; PMCID: PMC522194.
    39. Lizewski SE, Schurr JR, Jackson DW, Frisk A, Carterson AJ, Schurr MJ. Identification of AlgR-regulated genes in Pseudomonas aeruginosa by use of microarray analysis. J Bacteriol. 2004 Sep; 186(17):5672-84. PMID: 15317771; PMCID: PMC516850.
    40. Frisk A, Schurr JR, Wang G, Bertucci DC, Marrero L, Hwang SH, Hassett DJ, Schurr MJ. Transcriptome analysis of Pseudomonas aeruginosa after interaction with human airway epithelial cells. Infect Immun. 2004 Sep; 72(9):5433-8. PMID: 15322041; PMCID: PMC517424.
    41. Dang YN, Rao A, Kastl PR, Blake RC, Schurr MJ, Blake DA. Quantifying Pseudomonas aeruginosa adhesion to contact lenses. Eye Contact Lens. 2003 Apr; 29(2):65-8. PMID: 12695704.
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    42. Lizewski SE, Lundberg DS, Schurr MJ. The transcriptional regulator AlgR is essential for Pseudomonas aeruginosa pathogenesis. Infect Immun. 2002 Nov; 70(11):6083-93. PMID: 12379685; PMCID: PMC130412.
    43. Wilson JW, Schurr MJ, LeBlanc CL, Ramamurthy R, Buchanan KL, Nickerson CA. Mechanisms of bacterial pathogenicity. Postgrad Med J. 2002 Apr; 78(918):216-24. PMID: 11930024; PMCID: PMC1742320.
    44. Boucher JC, Schurr MJ, Deretic V. Dual regulation of mucoidy in Pseudomonas aeruginosa and sigma factor antagonism. Mol Microbiol. 2000 Apr; 36(2):341-51. PMID: 10792721.
      View in: PubMed
    45. Boucher JC, Schurr MJ, Yu H, Rowen DW, Deretic V. Pseudomonas aeruginosa in cystic fibrosis: role of mucC in the regulation of alginate production and stress sensitivity. Microbiology. 1997 Nov; 143 ( Pt 11):3473-80. PMID: 9387225.
      View in: PubMed
    46. Schurr MJ, Deretic V. Microbial pathogenesis in cystic fibrosis: co-ordinate regulation of heat-shock response and conversion to mucoidy in Pseudomonas aeruginosa. Mol Microbiol. 1997 Apr; 24(2):411-20. PMID: 9159526.
      View in: PubMed
    47. Yu H, Mudd M, Boucher JC, Schurr MJ, Deretic V. Identification of the algZ gene upstream of the response regulator algR and its participation in control of alginate production in Pseudomonas aeruginosa. J Bacteriol. 1997 Jan; 179(1):187-93. PMID: 8981997; PMCID: PMC178678.
    48. Schurr MJ, Yu H, Martinez-Salazar JM, Boucher JC, Deretic V. Control of AlgU, a member of the sigma E-like family of stress sigma factors, by the negative regulators MucA and MucB and Pseudomonas aeruginosa conversion to mucoidy in cystic fibrosis. J Bacteriol. 1996 Aug; 178(16):4997-5004. PMID: 8759866; PMCID: PMC178285.
    49. Boucher JC, Martinez-Salazar J, Schurr MJ, Mudd MH, Yu H, Deretic V. Two distinct loci affecting conversion to mucoidy in Pseudomonas aeruginosa in cystic fibrosis encode homologs of the serine protease HtrA. J Bacteriol. 1996 Jan; 178(2):511-23. PMID: 8550474; PMCID: PMC177686.
    50. Schurr MJ, Yu H, Martinez-Salazar JM, Hibler NS, Deretic V. Biochemical characterization and posttranslational modification of AlgU, a regulator of stress response in Pseudomonas aeruginosa. Biochem Biophys Res Commun. 1995 Nov 22; 216(3):874-80. PMID: 7488207.
      View in: PubMed
    51. Schurr MJ, Yu H, Boucher JC, Hibler NS, Deretic V. Multiple promoters and induction by heat shock of the gene encoding the alternative sigma factor AlgU (sigma E) which controls mucoidy in cystic fibrosis isolates of Pseudomonas aeruginosa. J Bacteriol. 1995 Oct; 177(19):5670-9. PMID: 7559357; PMCID: PMC177379.
    52. Deretic V, Schurr MJ, Yu H. Pseudomonas aeruginosa, mucoidy and the chronic infection phenotype in cystic fibrosis. Trends Microbiol. 1995 Sep; 3(9):351-6. PMID: 8520888.
      View in: PubMed
    53. Yu H, Schurr MJ, Deretic V. Functional equivalence of Escherichia coli sigma E and Pseudomonas aeruginosa AlgU: E. coli rpoE restores mucoidy and reduces sensitivity to reactive oxygen intermediates in algU mutants of P. aeruginosa. J Bacteriol. 1995 Jun; 177(11):3259-68. PMID: 7768826; PMCID: PMC177019.
    54. Schurr MJ, Vickrey JF, Kumar AP, Campbell AL, Cunin R, Benjamin RC, Shanley MS, O'Donovan GA. Aspartate transcarbamoylase genes of Pseudomonas putida: requirement for an inactive dihydroorotase for assembly into the dodecameric holoenzyme. J Bacteriol. 1995 Apr; 177(7):1751-9. PMID: 7896697; PMCID: PMC176802.
    55. Martin DW, Schurr MJ, Yu H, Deretic V. Analysis of promoters controlled by the putative sigma factor AlgU regulating conversion to mucoidy in Pseudomonas aeruginosa: relationship to sigma E and stress response. J Bacteriol. 1994 Nov; 176(21):6688-96. PMID: 7961422; PMCID: PMC197026.
    56. Schurr MJ, Martin DW, Mudd MH, Deretic V. Gene cluster controlling conversion to alginate-overproducing phenotype in Pseudomonas aeruginosa: functional analysis in a heterologous host and role in the instability of mucoidy. J Bacteriol. 1994 Jun; 176(11):3375-82. PMID: 8195094; PMCID: PMC205510.
    57. Deretic V, Schurr MJ, Boucher JC, Martin DW. Conversion of Pseudomonas aeruginosa to mucoidy in cystic fibrosis: environmental stress and regulation of bacterial virulence by alternative sigma factors. J Bacteriol. 1994 May; 176(10):2773-80. PMID: 8188579; PMCID: PMC205429.
    58. Deretic V, Martin DW, Schurr MJ, Mudd MH, Hibler NS, Curcic R, Boucher JC. Conversion to mucoidy in Pseudomonas aeruginosa. Biotechnology (N Y). 1993 Oct; 11(10):1133-6. PMID: 7764093.
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    59. Martin DW, Schurr MJ, Mudd MH, Govan JR, Holloway BW, Deretic V. Mechanism of conversion to mucoidy in Pseudomonas aeruginosa infecting cystic fibrosis patients. Proc Natl Acad Sci U S A. 1993 Sep 15; 90(18):8377-81. PMID: 8378309; PMCID: PMC47359.
    60. Martin DW, Schurr MJ, Mudd MH, Deretic V. Differentiation of Pseudomonas aeruginosa into the alginate-producing form: inactivation of mucB causes conversion to mucoidy. Mol Microbiol. 1993 Aug; 9(3):497-506. PMID: 8412698.
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    61. Schurr MJ, Martin DW, Mudd MH, Hibler NS, Boucher JC, Deretic V. The algD promoter: regulation of alginate production by Pseudomonas aeruginosa in cystic fibrosis. Cell Mol Biol Res. 1993; 39(4):371-6. PMID: 8312973.
      View in: PubMed
    62. Zimmerman EG, Akins DR, Planz JV, Schurr MJ. A rapid procedure for isolating mitochondrial DNA. Gene Anal Tech. 1988 Sep-Oct; 5(5):102-4. PMID: 2847966.
      View in: PubMed
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