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Jane E . Reusch

TitleProfessor
InstitutionUniversity of Colorado Denver - Anschutz Medical Campus
DepartmentSOM-MED
Phone303/399-8020

    Collapse Biography 
    Collapse education and training
    University of Notre Dame, South Bend, INBS05/1981Biology and Theology
    Northwestern University SOM, Chicago, IL05/1984Medicine
    University of Minnesota, Minneapolis, MNMD05/1986Medicine
    University of Colorado, Denver, CO06/1989Internal Medicine
    University of Colorado, Denver, CO06/1991Diabetes, Endocrinology and Metabolism

    Collapse Research 
    Collapse research activities and funding
    R01DK130351     (REUSCH, JANE E)Sep 15, 2021 - Aug 31, 2024
    NIH
    Impact of SARS CoV2 on post-hospital recovery of carbohydrate and muscle metabolism: role of endothelial injury
    Role: Principal Investigator
    R01DK124344     (REUSCH, JANE E)Apr 1, 2021 - Mar 31, 2027
    NIH
    Role of Microvascular insulin resistance and cardiorespiratory fitness in diabetes
    Role: Principal Investigator
    P30DK116073     (SUSSEL, LORI)Apr 1, 2020 - Mar 31, 2025
    NIH
    UC Denver Diabetes Research Center
    Role: Co-Investigator
    I01CX001532     (REUSCH, JANE E)Jul 1, 2017 - Jun 30, 2023
    NIH
    Cardiovascular Mechanisms of Exercise Intolerance in Diabetes and the Role of Sex
    Role: Principal Investigator
    I01BX002046     (REUSCH, JANE E)Oct 1, 2013 - Mar 31, 2024
    NIH
    Targeting Microvascular Contributors to Impaired Functional Exercise Capacity in Diabetes
    Role: Principal Investigator
    R01DK064741     (REUSCH, JANE E)Apr 15, 2004 - Mar 31, 2010
    NIH
    Transcriptional Regulation of PDGF Receptor Alpha
    Role: Principal Investigator
    K08DK002351     (REUSCH, JANE E)Jun 15, 1995 - May 31, 2001
    NIH
    INSULIN REGULATION OF NUCLEAR PROTEIN PHOSPHATASE 2A
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Regensteiner JG, McNeil M, Faubion SS, Bairey-Merz CN, Gulati M, Joffe H, Redberg RF, Rosen SE, Reusch JE, Klein W. Barriers and solutions in women's health research and clinical care: a call to action. Lancet Reg Health Am. 2025 Apr; 44:101037. PMID: 40143925.
      View in: PubMed
    2. Abushamat LA, Jia X, Xu L, Cheng C, Ndumele CE, Sun C, Windham BG, Matsushita K, Yu B, Nambi V, Bozkurt B, Reusch JEB, Rebholz CM, Selvin E, Ballantyne CM, Hoogeveen RC. Does Adiponectin Inform Cardiovascular?Risk in Older Adults?: The ARIC Study. JACC Adv. 2025 Mar; 4(3):101625. PMID: 39983616.
      View in: PubMed
    3. Abushamat LA, Yu B, Hoogeveen RC, Sun C, Cheng C, Hartig SM, Herman MA, Balasubramanyam A, Reusch JE, Selvin E, Ndumele CE, Nambi V, Ballantyne CM. Erythritol, Erythronate, and Cardiovascular Outcomes in Older?Adults?in the ARIC Study. JACC Adv. 2025 Mar; 4(3):101605. PMID: 39983608.
      View in: PubMed
    4. Henckel MM, Chun JH, Knaub LA, Pott GB, James GE, Hunter KS, Shandas R, Walker LA, Reusch JE, Keller AC. Thermoneutral-housed rats demonstrate impaired perivascular adipose tissue and vascular crosstalk. J Hypertens. 2025 May 01; 43(5):752-767. PMID: 39927881.
      View in: PubMed
    5. Soff S, Yoo YJ, Bramante C, Reusch JEB, Huling JD, Hall MA, Brannock D, Sturmer T, Butzin-Dozier Z, Wong R, Moffitt R. Association of glycemic control with Long COVID in patients with type 2 diabetes: findings from the National COVID Cohort Collaborative (N3C). BMJ Open Diabetes Res Care. 2025 Feb 04; 13(1). PMID: 39904520.
      View in: PubMed
    6. Kao DP, Martin JL, Aquilante CL, Shalowitz EL, Leyba K, Kudron E, Reusch JEB, Regensteiner JG. Sex-differences in reporting of statin-associated diabetes mellitus to the US Food and Drug Administration. BMJ Open Diabetes Res Care. 2024 Dec 05; 12(6). PMID: 39638563.
      View in: PubMed
    7. Wong R, Hall MA, Wiggen T, Johnson SG, Huling JD, Turner LE, Wilkins KJ, Yeh HC, St?rmer T, Bramante CT, Buse JB, Reusch J. Effect of SARS-CoV-2 Infection on Incident Diabetes by Viral Variant: Findings From the National COVID Cohort Collaborative (N3C). Diabetes Care. 2024 Oct 01; 47(10):1846-1854. PMID: 39207804.
      View in: PubMed
    8. Kumar TR, Reusch JEB, Kohrt WM, Regensteiner JG. Sex Differences Across the Lifespan: A Focus on Cardiometabolism. J Womens Health (Larchmt). 2024 Oct; 33(10):1299-1305. PMID: 39056116.
      View in: PubMed
    9. Gottlieb D, Abushamat LA, Nadeau KJ, Regensteiner JG, Reusch JEB, Tommerdahl KL, Rice J, Knaub LA, Monaco CMF, Hawke TJ, Perry CGR, Cree MG, Schauer IE. Muscle mitochondrial function is impaired in adults with type 1 diabetes. J Diabetes Complications. 2024 Aug; 38(8):108798. PMID: 38991492.
      View in: PubMed
    10. Chang EI, Stremming J, Knaub LA, Wesolowski SR, Rozance PJ, Sucharov CC, Reusch JEB, Brown LD. Mitochondrial respiration is lower in the intrauterine growth-restricted fetal sheep heart. J Physiol. 2024 Jun; 602(12):2697-2715. PMID: 38743350.
      View in: PubMed
    11. Henckel MM, Chun JH, Knaub LA, Pott GB, James GE, Hunter KS, Shandas R, Walker LA, Reusch JE, Keller AC. Perivascular adipose tissue remodeling impairs vasoreactivity in thermoneutral-housed rats. bioRxiv. 2024 May 13. PMID: 38798439.
      View in: PubMed
    12. Huebschmann AG, Scalzo RL, Yang X, Schmiege SJ, Reusch JEB, Dunn AL, Chapman K, Regensteiner JG. Type 2 diabetes is linked to higher physiologic markers of effort during exercise. Front Clin Diabetes Healthc. 2024; 5:1346716. PMID: 38741611.
      View in: PubMed
    13. Abushamat LA, Schauer IE, Low Wang CC, Mitchell S, Herlache L, Bridenstine M, Durbin R, Snell-Bergeon JK, Regensteiner JG, Reusch JE. Rosiglitazone improves insulin resistance but does not improve exercise capacity in individuals with impaired glucose tolerance: A randomized clinical study. J Investig Med. 2024 03; 72(3):294-304. PMID: 38148342.
      View in: PubMed
    14. Greenstein AS, Reusch JEB, Heagerty AM. Is it time to recommend cardiovascular protection for all? J Hypertens. 2024 02 01; 42(2):224-226. PMID: 38165051.
      View in: PubMed
    15. Abel ED, Ingelfinger JR, Linhales Barker S, Peek M, Reusch JEB, Rosen CJ. Type 2 Diabetes - Controlling the Epidemic, Episode 4: Understanding Old and New Therapies for Diabetes. N Engl J Med. 2023 10 19; 389(16):e31. PMID: 37851873.
      View in: PubMed
    16. Hulett NA, Knaub LA, Hull SE, Pott GB, Peelor R, Miller BF, Shankar K, Rudolph MC, Reusch JEB, Scalzo RL. Sex Differences in the Skeletal Muscle Response to a High Fat, High Sucrose Diet in Rats. Nutrients. 2023 Oct 19; 15(20). PMID: 37892512.
      View in: PubMed
    17. Abel ED, Ingelfinger JR, Linhales Barker S, Lopez D, Mejia M, Peek M, Reusch JEB, Rosen CJ. Type 2 Diabetes - Controlling the Epidemic, Episode 3: Fostering Patient Engagement and Lifestyle Modifications. N Engl J Med. 2023 10 05; 389(14):e27. PMID: 37792611.
      View in: PubMed
    18. Abel ED, Ingelfinger JR, Kolko J, Linhales Barker S, Lopez D, Mejia M, Peek M, Reusch JEB, Rosen CJ. Type 2 Diabetes - Controlling the Epidemic, Episode 2: After the Diagnosis - Making a Plan and Addressing Social Determinants of Health. N Engl J Med. 2023 09 21; 389(12):e23. PMID: 37733307.
      View in: PubMed
    19. Abel ED, Giffin J, Ingelfinger JR, Peek M, Reusch JEB, Rosen CJ, Sagendorf A, Thomas E. Type 2 Diabetes - Controlling the Epidemic, Episode 1: Understanding and Preventing Type 2 Diabetes. N Engl J Med. 2023 Sep 07; 389(10):e18. PMID: 37672693.
      View in: PubMed
    20. Thielen SC, Reusch JEB, Regensteiner JG. A narrative review of exercise participation among adults with prediabetes or type 2 diabetes: barriers and solutions. Front Clin Diabetes Healthc. 2023; 4:1218692. PMID: 37711232.
      View in: PubMed
    21. Abushamat LA, Enge D, Fujiwara T, Sch?fer M, Clark EW, Englund EK, Scalzo RL, Johnston A, Rafferty D, Schauer IE, Whipple MO, Hunter K, Huebschmann AG, Nadeau KJ, Jarvis K, Barker AJ, Regensteiner JG, Reusch JEB. Obesity dominates early effects on cardiac structure and arterial stiffness in people with type 2 diabetes. J Hypertens. 2023 11 01; 41(11):1775-1784. PMID: 37589719.
      View in: PubMed
    22. Fridman V, Sillau S, Ritchie A, Bockhorst J, Coughlan C, Araya P, Espinosa JM, Smith K, Lange EM, Lange LA, Ghormli LE, Drews KL, Zeitler P, Reusch JEB. Plasma neurofilament light chain concentrations are elevated in youth-onset type 2 diabetes and associated with neuropathy. J Peripher Nerv Syst. 2023 09; 28(3):460-470. PMID: 37341347.
      View in: PubMed
    23. Reusch JE. Building a Better Insulin - Whom Will It Help? N Engl J Med. 2023 Jul 27; 389(4):372-373. PMID: 37494489.
      View in: PubMed
    24. Wong R, Lam E, Bramante CT, Johnson SG, Reusch J, Wilkins KJ, Yeh HC. Does COVID-19 Infection Increase the Risk of Diabetes? Current Evidence. Curr Diab Rep. 2023 08; 23(8):207-216. PMID: 37284921.
      View in: PubMed
    25. Reddy NV, Yeh HC, Tronieri JS, St?rmer T, Buse JB, Reusch JE, Johnson SG, Wong R, Moffitt R, Wilkins KJ, Harper J, Bramante CT. Are fewer cases of diabetes mellitus diagnosed in the months after SARS-CoV-2 infection? A population-level view in the EHR-based RECOVER program. J Clin Transl Sci. 2023; 7(1):e90. PMID: 37125061.
      View in: PubMed
    26. Sch?fer M, Browne LP, Truong U, Bjornstad P, Tell S, Snell-Bergeon J, Baumgartner A, Hunter KS, Reusch JEB, Barker AJ, Nadeau KJ, Schauer IE. Bromocriptine Improves Central Aortic Stiffness in Adolescents With Type 1 Diabetes: Arterial Health Results From the BCQR-T1D Study. Hypertension. 2023 02; 80(2):482-491. PMID: 36472197.
      View in: PubMed
    27. Reddy NV, Yeh HC, Tronieri JS, St?rmer T, Buse JB, Reusch JE, Johnson SG, Wong R, Moffitt R, Wilkins KJ, Harper J, Bramante CT. Are fewer cases of diabetes mellitus diagnosed in the months after SARS-CoV-2 infection? medRxiv. 2022 Dec 04. PMID: 36482974.
      View in: PubMed
    28. Wong R, Vaddavalli R, Hall MA, Patel MV, Bramante CT, Casarighi E, Johnson SG, Lingam V, Miller JD, Reusch J, Saltz M, St?rmer T, Tronieri JS, Wilkins KJ, Buse JB, Saltz J, Huling JD, Moffitt R. Effect of SARS-CoV-2 Infection and Infection Severity on Longer-Term Glycemic Control and Weight in People With Type 2 Diabetes. Diabetes Care. 2022 11 01; 45(11):2709-2717. PMID: 36098660.
      View in: PubMed
    29. Erickson ML, Allen JM, Beavers DP, Collins LM, Davidson KW, Erickson KI, Esser KA, Hesselink MKC, Moreau KL, Laber EB, Peterson CA, Peterson CM, Reusch JE, Thyfault JP, Youngstedt SD, Zierath JR, Goodpaster BH, LeBrasseur NK, Buford TW, Sparks LM. Understanding heterogeneity of responses to, and optimizing clinical efficacy of, exercise training in older adults: NIH NIA Workshop summary. Geroscience. 2023 02; 45(1):569-589. PMID: 36242693.
      View in: PubMed
    30. Keller AC, Chun JH, Knaub LA, Henckel MM, Hull SE, Scalzo RL, Pott GB, Walker LA, Reusch JEB. Thermoneutrality induces vascular dysfunction and impaired metabolic function in male Wistar rats: a new model of vascular disease. J Hypertens. 2022 11 01; 40(11):2133-2146. PMID: 35881464.
      View in: PubMed
    31. Whipple MO, Pinto AJ, Abushamat LA, Bergouignan A, Chapman K, Huebschmann AG, Masters KS, Nadeau KJ, Scalzo RL, Schauer IE, Rafferty D, Reusch JEB, Regensteiner JG. Sex Differences in Physical Activity Among Individuals With Type 2 Diabetes Across the Life Span: A Systematic Review and Meta-analysis. Diabetes Care. 2022 09 01; 45(9):2163-2177. PMID: 36044665.
      View in: PubMed
    32. Chun JH, Henckel MM, Knaub LA, Hull SE, Pott GB, Ramirez DG, Reusch JE, Keller AC. (-)-Epicatechin Reverses Glucose Intolerance in Rats Housed at Thermoneutrality. Planta Med. 2022 Aug; 88(9-10):735-744. PMID: 35777366.
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    33. Raghavan S, Warsavage T, Liu WG, Raffle K, Josey K, Saxon DR, Phillips LS, Caplan L, Reusch JEB. Trends in Timing of and Glycemia at Initiation of Second-line Type 2 Diabetes Treatment in U.S. Adults. Diabetes Care. 2022 06 02; 45(6):1335-1345. PMID: 35344584.
      View in: PubMed
    34. Huebschmann AG, Glasgow RE, Leavitt IM, Chapman K, Rice JD, Lockhart S, Stevens-Lapsley JE, Reusch JEB, Dunn AL, Regensteiner JG. Integrating a physical activity coaching intervention into diabetes care: a mixed-methods evaluation of a pilot pragmatic trial. Transl Behav Med. 2022 05 25; 12(4):601-610. PMID: 35312788.
      View in: PubMed
    35. Vaughan OR, Rosario FJ, Chan J, Cox LA, Ferchaud-Roucher V, Zemski-Berry KA, Reusch JEB, Keller AC, Powell TL, Jansson T. Maternal obesity causes fetal cardiac hypertrophy and alters adult offspring myocardial metabolism in mice. J Physiol. 2022 07; 600(13):3169-3191. PMID: 35545608.
      View in: PubMed
    36. Edward JA, Josey K, Bahn G, Caplan L, Reusch JEB, Reaven P, Ghosh D, Raghavan S. Heterogeneous treatment effects of intensive glycemic control on major adverse cardiovascular events in the ACCORD and VADT trials: a machine-learning analysis. Cardiovasc Diabetol. 2022 04 27; 21(1):58. PMID: 35477454.
      View in: PubMed
    37. Regensteiner JG, Reusch JEB. Sex Differences in Cardiovascular Consequences of Hypertension, Obesity, and Diabetes: JACC Focus Seminar 4/7. J Am Coll Cardiol. 2022 04 19; 79(15):1492-1505. PMID: 35422246.
      View in: PubMed
    38. Chun JH, Henckel MM, Knaub LA, Hull SE, Pott GB, Walker LA, Reusch JE, Keller AC. (-)-Epicatechin Improves Vasoreactivity and Mitochondrial Respiration in Thermoneutral-Housed Wistar Rat Vasculature. Nutrients. 2022 Mar 05; 14(5). PMID: 35268072.
      View in: PubMed
    39. Hulett NA, Scalzo RL, Reusch JEB. Glucose Uptake by Skeletal Muscle within the Contexts of Type 2 Diabetes and Exercise: An Integrated Approach. Nutrients. 2022 Feb 03; 14(3). PMID: 35277006.
      View in: PubMed
    40. De Jong NP, Rudolph MC, Jackman MR, Sharp RR, Jones K, Houck J, Pan Z, Reusch JEB, MacLean PS, Bessesen DH, Bergouignan A. Short-Term Adaptations in Skeletal Muscle Mitochondrial Oxidative Capacity and Metabolic Pathways to Breaking up Sedentary Behaviors in Overweight or Obese Adults. Nutrients. 2022 Jan 20; 14(3). PMID: 35276813.
      View in: PubMed
    41. Stremming J, Chang EI, Knaub LA, Armstrong ML, Baker PR, Wesolowski SR, Reisdorph N, Reusch JEB, Brown LD. Lower citrate synthase activity, mitochondrial complex expression, and fewer oxidative myofibers characterize skeletal muscle from growth-restricted fetal sheep. Am J Physiol Regul Integr Comp Physiol. 2022 03 01; 322(3):R228-R240. PMID: 34907787.
      View in: PubMed
    42. Scalzo RL, Foright RM, Hull SE, Knaub LA, Johnson-Murguia S, Kinanee F, Kaplan J, Houck JA, Johnson G, Sharp RR, Gillen AE, Jones KL, Zhang AMY, Johnson JD, MacLean PS, Reusch JEB, Wright-Hobart S, Wellberg EA. Breast Cancer Endocrine Therapy Promotes Weight Gain With Distinct Adipose Tissue Effects in Lean and Obese Female Mice. Endocrinology. 2021 11 01; 162(11). PMID: 34410380.
      View in: PubMed
    43. Love KM, Barrett EJ, Malin SK, Reusch JEB, Regensteiner JG, Liu Z. Diabetes pathogenesis and management: the endothelium comes of age. J Mol Cell Biol. 2021 10 21; 13(7):500-512. PMID: 33787922.
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    44. Abushamat LA, Reusch JEB. Evolving Concepts of Type 2 Diabetes Management. Med Clin North Am. 2021 Nov; 105(6):955-966. PMID: 34688420.
      View in: PubMed
    45. Jankowski CM, Wilson MP, MaWhinney S, Reusch J, Knaub L, Hull S, Erlandson KM. Blunted Muscle Mitochondrial Responses to Exercise Training in Older Adults With HIV. J Infect Dis. 2021 08 16; 224(4):679-683. PMID: 33378424.
      View in: PubMed
    46. Sandoval DA, Alonso LC, Gannon M, Sander M, Sussel L, Reusch JEB. Career Advancement for Women in Diabetes-Related Research: Developing and Retaining Female Talent. Diabetes. 2021 08 01; 70(8):1634-1637. PMID: 35381060.
      View in: PubMed
    47. Sandoval DA, Alonso LC, Gannon M, Sander M, Sussel L, Reusch JEB. Career Advancement for Women in Diabetes-Related Research: Developing and Retaining Female Talent. Diabetes Care. 2021 08; 44(8):1744-1747. PMID: 34131046.
      View in: PubMed
    48. Whipple MO, Masters KS, Huebschmann AG, Scalzo RL, Reusch JE, Bergouignan A, Regensteiner JG. Acute effects of sedentary breaks on vascular health in adults at risk for type 2 diabetes: A systematic review. Vasc Med. 2021 08; 26(4):448-458. PMID: 33977799.
      View in: PubMed
    49. Scalzo RL, Schauer IE, Rafferty D, Knaub LA, Kvaratskhelia N, Johnson TK, Pott GB, Abushamat LA, Whipple MO, Huebschmann AG, Cree-Green M, Reusch JEB, Regensteiner JG. Single-leg exercise training augments in vivo skeletal muscle oxidative flux and vascular content and function in adults with type 2 diabetes. J Physiol. 2022 02; 600(4):963-978. PMID: 33569797.
      View in: PubMed
    50. Melena I, Bjornstad P, Sch?fer M, Hunter KS, Barker AJ, Baumgartner A, Chung L, Wiromrat P, Truong U, Reusch JEB, Nadeau KJ. Serum copeptin and NT-proBNP is associated with central aortic stiffness and flow hemodynamics in adolescents with type 1 diabetes: A pilot study. J Diabetes Complications. 2021 05; 35(5):107883. PMID: 33712333.
      View in: PubMed
    51. Redondo MJ, Libman I, Maahs DM, Lyons SK, Saraco M, Reusch J, Rodriguez H, DiMeglio LA. The Evolution of Hemoglobin A1c Targets for Youth With Type 1 Diabetes: Rationale and Supporting Evidence. Diabetes Care. 2021 02; 44(2):301-312. PMID: 33431422.
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    52. Fridman V, Zarini S, Sillau S, Harrison K, Bergman BC, Feldman EL, Reusch JEB, Callaghan BC. Altered plasma serine and 1-deoxydihydroceramide profiles are associated with diabetic neuropathy in type 2 diabetes and obesity. J Diabetes Complications. 2021 04; 35(4):107852. PMID: 33485750.
      View in: PubMed
    53. Tommerdahl KL, Baumgartner K, Sch?fer M, Bjornstad P, Melena I, Hegemann S, Baumgartner AD, Pyle L, Cree-Green M, Truong U, Browne L, Regensteiner JG, Reusch JEB, Nadeau KJ. Impact of Obesity on Measures of Cardiovascular and Kidney Health in Youth With Type 1 Diabetes as Compared With Youth With Type 2 Diabetes. Diabetes Care. 2021 03; 44(3):795-803. PMID: 33402367.
      View in: PubMed
    54. Tommerdahl KL, Bjornstad P, Kendrick J, Cree-Green M, Baumgartner AD, Pyle L, Reusch JEB, Nadeau KJ. Results from the Effects of MEtformin on cardiovasculaR function in AdoLescents with type 1 Diabetes (EMERALD) study: A brief report of kidney and inflammatory outcomes. Diabetes Obes Metab. 2021 03; 23(3):844-849. PMID: 33236509.
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    55. Cree-Green M, Carreau AM, Davis SM, Frohnert BI, Kaar JL, Ma NS, Nokoff NJ, Reusch JEB, Simon SL, Nadeau KJ. Peer mentoring for professional and personal growth in academic medicine. J Investig Med. 2020 08; 68(6):1128-1134. PMID: 32641352.
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    56. Keller A, Hull SE, Elajaili H, Johnston A, Knaub LA, Chun JH, Walker L, Nozik-Grayck E, Reusch JEB. (-)-Epicatechin Modulates Mitochondrial Redox in Vascular Cell Models of Oxidative Stress. Oxid Med Cell Longev. 2020; 2020:6392629. PMID: 32587663.
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    57. Abushamat LA, McClatchey PM, Scalzo RL, Schauer I, Huebschmann AG, Nadeau KJ, Liu Z, Regensteiner JG, Reusch JEB. Mechanistic Causes of Reduced Cardiorespiratory Fitness in Type 2 Diabetes. J Endocr Soc. 2020 Jul 01; 4(7):bvaa063. PMID: 32666009.
      View in: PubMed
    58. Sch?fer M, Nadeau KJ, Reusch JEB. Cardiovascular disease in young People with Type 1 Diabetes: Search for Cardiovascular Biomarkers. J Diabetes Complications. 2020 10; 34(10):107651. PMID: 32546422.
      View in: PubMed
    59. Kumar TR, Reusch JEB, Kohrt WM, Regensteiner JG. Sex Differences Across the Lifespan: A Focus on Cardiometabolism. J Womens Health (Larchmt). 2020 07; 29(7):899-909. PMID: 32423340.
      View in: PubMed
    60. Sch?fer M, Bjornstad P, Frank BS, Baumgartner A, Truong U, Enge D, von Alvensleben JC, Mitchell MB, Ivy DD, Barker AJ, Reusch JEB, Nadeau KJ. Frequency of Reduced Left Ventricular Contractile Efficiency and Discoordinated Myocardial Relaxation in Patients Aged 16 to 21 Years With Type 1 Diabetes Mellitus (from the Emerald Study). Am J Cardiol. 2020 08 01; 128:45-53. PMID: 32650923.
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    61. Raghavan S, Liu WG, Berkowitz SA, Bar?n AE, Plomondon ME, Maddox TM, Reusch JEB, Ho PM, Caplan L. Association of Glycemic Control Trajectory with Short-Term Mortality in Diabetes Patients with High Cardiovascular Risk: a Joint Latent Class Modeling Study. J Gen Intern Med. 2020 08; 35(8):2266-2273. PMID: 32333313.
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    62. Love KM, Liu J, Regensteiner JG, Reusch JEB, Liu Z. GLP-1 and insulin regulation of skeletal and cardiac muscle microvascular perfusion in type 2 diabetes. J Diabetes. 2020 Jul; 12(7):488-498. PMID: 32274893.
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    63. Tinsley LJ, Wong ND, Reusch JEB, Arnold SV, Kosiborod MN, Tang Y, Laffel LM, Mehta SN. Regional differences in the management of cardiovascular risk factors among adults with diabetes: An evaluation of the Diabetes Collaborative Registry. J Diabetes Complications. 2020 08; 34(8):107591. PMID: 32471789.
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    64. Garat CV, Majka SM, Sullivan TM, Crossno JT, Reusch JEB, Klemm DJ. CREB depletion in smooth muscle cells promotes medial thickening, adventitial fibrosis and elicits pulmonary hypertension. Pulm Circ. 2020 Apr-Jun; 10(2):2045894019898374. PMID: 32313640.
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    65. Sharma A, Pagidipati NJ, Califf RM, McGuire DK, Green JB, Demets D, George JT, Gerstein HC, Hobbs T, Holman RR, Lawson FC, Leiter LA, Pfeffer MA, Reusch J, Riesmeyer JS, Roe MT, Rosenberg Y, Temple R, Wiviott S, McMurray J, Granger C. Impact of Regulatory Guidance on Evaluating Cardiovascular Risk of New Glucose-Lowering Therapies to Treat Type 2 Diabetes Mellitus: Lessons Learned and Future Directions. Circulation. 2020 03 10; 141(10):843-862. PMID: 31992065.
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    66. Hudish LI, Reusch JE, Sussel L. ? Cell dysfunction during progression of metabolic syndrome to type 2 diabetes. J Clin Invest. 2019 10 01; 129(10):4001-4008. PMID: 31424428.
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    67. Huebschmann AG, Huxley RR, Kohrt WM, Zeitler P, Regensteiner JG, Reusch JEB. Sex differences in the burden of type 2 diabetes and cardiovascular risk across the life course. Diabetologia. 2019 10; 62(10):1761-1772. PMID: 31451872.
      View in: PubMed
    68. Scalzo RL, Rafferty D, Schauer I, Huebschmann AG, Cree-Green M, Reusch JEB, Regensteiner JG. Sitagliptin improves diastolic cardiac function but not cardiorespiratory fitness in adults with type 2 diabetes. J Diabetes Complications. 2019 08; 33(8):561-566. PMID: 31182338.
      View in: PubMed
    69. Reusch JEB. The Diabetes Story: A Call to Action : 2018 Presidential Address. Diabetes Care. 2019 05; 42(5):713-717. PMID: 31010941.
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    70. Keller AC, Klawitter J, Hildreth KL, Christians U, Putnam K, Kohrt WM, Reusch JEB, Moreau KL. Elevated plasma homocysteine and cysteine are associated with endothelial dysfunction across menopausal stages in healthy women. J Appl Physiol (1985). 2019 06 01; 126(6):1533-1540. PMID: 30896357.
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    71. Bjornstad P, Sch?fer M, Truong U, Cree-Green M, Pyle L, Baumgartner A, Garcia Reyes Y, Maniatis A, Nayak S, Wadwa RP, Browne LP, Reusch JEB, Nadeau KJ. Metformin Improves Insulin Sensitivity and Vascular Health in Youth With Type 1 Diabetes Mellitus. Circulation. 2018 12 18; 138(25):2895-2907. PMID: 30566007.
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    72. Tyagi A, Nguyen CU, Chong T, Michel CR, Fritz KS, Reisdorph N, Knaub L, Reusch JEB, Pugazhenthi S. SIRT3 deficiency-induced mitochondrial dysfunction and inflammasome formation in the brain. Sci Rep. 2018 12 03; 8(1):17547. PMID: 30510203.
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    73. Keller AC, Knaub LA, Scalzo RL, Hull SE, Johnston AE, Walker LA, Reusch JEB. Sepiapterin Improves Vascular Reactivity and Insulin-Stimulated Glucose in Wistar Rats. Oxid Med Cell Longev. 2018; 2018:7363485. PMID: 30344886.
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    74. McClatchey PM, Mignemi NA, Xu Z, Williams IM, Reusch JEB, McGuinness OP, Wasserman DH. Automated quantification of microvascular perfusion. Microcirculation. 2018 08; 25(6):e12482. PMID: 29908041.
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    105. Irwin DC, Garat CV, Crossno JT, MacLean PS, Sullivan TM, Erickson PF, Jackman MR, Harral JW, Reusch JE, Klemm DJ. Obesity-related pulmonary arterial hypertension in rats correlates with increased circulating inflammatory cytokines and lipids and with oxidant damage in the arterial wall but not with hypoxia. Pulm Circ. 2014 Dec; 4(4):638-53. PMID: 25610600.
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    133. Venkatachalam K, Venkatesan B, Valente AJ, Melby PC, Nandish S, Reusch JE, Clark RA, Chandrasekar B. WISP1, a pro-mitogenic, pro-survival factor, mediates tumor necrosis factor-alpha (TNF-alpha)-stimulated cardiac fibroblast proliferation but inhibits TNF-alpha-induced cardiomyocyte death. J Biol Chem. 2009 May 22; 284(21):14414-27. PMID: 19339243.
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    135. Schauer IE, Reusch JE. Nonesterified fatty acid exposure activates protective and mitogenic pathways in vascular smooth muscle cells by alternate signaling pathways. Metabolism. 2009 Mar; 58(3):319-27. PMID: 19217446.
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    136. Nadeau KJ, Ehlers LB, Aguirre LE, Reusch JE, Draznin B. Discordance between intramuscular triglyceride and insulin sensitivity in skeletal muscle of Zucker diabetic rats after treatment with fenofibrate and rosiglitazone. Diabetes Obes Metab. 2007 Sep; 9(5):714-23. PMID: 17697064.
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    137. Bauer TA, Reusch JE, Levi M, Regensteiner JG. Skeletal muscle deoxygenation after the onset of moderate exercise suggests slowed microvascular blood flow kinetics in type 2 diabetes. Diabetes Care. 2007 Nov; 30(11):2880-5. PMID: 17675540.
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    139. Sarkar SA, Gunter J, Bouchard R, Reusch JE, Wiseman A, Gill RG, Hutton JC, Pugazhenthi S. Dominant negative mutant forms of the cAMP response element binding protein induce apoptosis and decrease the anti-apoptotic action of growth factors in human islets. Diabetologia. 2007 Aug; 50(8):1649-59. PMID: 17593347.
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    144. Huebschmann AG, Regensteiner JG, Vlassara H, Reusch JE. Diabetes and advanced glycoxidation end products. Diabetes Care. 2006 Jun; 29(6):1420-32. PMID: 16732039.
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    145. Nadeau KJ, Ehlers LB, Aguirre LE, Moore RL, Jew KN, Ortmeyer HK, Hansen BC, Reusch JE, Draznin B. Exercise training and calorie restriction increase SREBP-1 expression and intramuscular triglyceride in skeletal muscle. Am J Physiol Endocrinol Metab. 2006 Jul; 291(1):E90-8. PMID: 16449296.
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    146. Regensteiner JG, Bauer TA, Reusch JE. Rosiglitazone improves exercise capacity in individuals with type 2 diabetes. Diabetes Care. 2005 Dec; 28(12):2877-83. PMID: 16306548.
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    147. Arany I, Megyesi JK, Reusch JE, Safirstein RL. CREB mediates ERK-induced survival of mouse renal tubular cells after oxidant stress. Kidney Int. 2005 Oct; 68(4):1573-82. PMID: 16164634.
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    148. Bergenstal RM, Nag SS, Reusch JE, Sajjan SG, Alexander CM. Macrovascular risk factors in patients with diabetes: physician treatment strategies and extent of control. Endocr Pract. 2005 May-Jun; 11(3):172-9. PMID: 16239203.
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    149. Drexler AJ, Nesto RW, Abrahamson MJ, Bakris G, Bell D, Brunzell J, Dandona P, Davidson J, Fonseca V, Fowler M, Frye R, Giles T, Haffner S, Hollenberg N, Hsueh W, Law R, Plutzky J, Ratner R, Reusch J, Selwyn A, Sowers J, Wyne K, Young LH. Evaluating the cardiovascular effects of the thiazolidinediones and their place in the management of type 2 diabetes in relation to the metabolic syndrome. Metab Syndr Relat Disord. 2005; 3(2):147-73. PMID: 18370723.
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    150. Reusch JE, Watson PA. Loss of CREB regulation of vascular smooth muscle cell quiescence in diabetes. Rev Endocr Metab Disord. 2004 Aug; 5(3):209-19. PMID: 15211092.
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    151. McCall DT, Sauaia A, Hamman RF, Reusch JE, Barton P. Are low-income elderly patients at risk for poor diabetes care? Diabetes Care. 2004 May; 27(5):1060-5. PMID: 15111521.
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    152. Reusch JE. Time management in academic medicine. J Investig Med. 2004 May; 52(4):259-61. PMID: 15521549.
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    153. Watt WC, Sakano H, Lee ZY, Reusch JE, Trinh K, Storm DR. Odorant stimulation enhances survival of olfactory sensory neurons via MAPK and CREB. Neuron. 2004 Mar 25; 41(6):955-67. PMID: 15046727.
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    154. Haskins K, Kench J, Powers K, Bradley B, Pugazhenthi S, Reusch J, McDuffie M. Role for oxidative stress in the regeneration of islet beta cells? J Investig Med. 2004 Jan; 52(1):45-9. PMID: 14989369.
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    155. Reusch JE, Regensteiner JG, Watson PA. Novel actions of thiazolidinediones on vascular function and exercise capacity. Am J Med. 2003 Dec 08; 115 Suppl 8A:69S-74S. PMID: 14678869.
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    156. Haskins K, Bradley B, Powers K, Fadok V, Flores S, Ling X, Pugazhenthi S, Reusch J, Kench J. Oxidative stress in type 1 diabetes. Ann N Y Acad Sci. 2003 Nov; 1005:43-54. PMID: 14679039.
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    157. Reusch JE. Diabetes, microvascular complications, and cardiovascular complications: what is it about glucose? J Clin Invest. 2003 Oct; 112(7):986-8. PMID: 14523035.
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    158. Reusch JE, Klemm DJ. Cyclic AMP response element-binding protein in the vessel wall: good or bad? Circulation. 2003 Sep 09; 108(10):1164-6. PMID: 12963681.
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    159. Brandenburg SL, Lindenfeld J, Reusch JE, Regensteiner JG. Cardiovascular risk in women with type 2 diabetes. Med Clin North Am. 2003 Sep; 87(5):955-69. PMID: 14621326.
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    160. Vaishnav D, Jambal P, Reusch JE, Pugazhenthi S. SP600125, an inhibitor of c-jun N-terminal kinase, activates CREB by a p38 MAPK-mediated pathway. Biochem Biophys Res Commun. 2003 Aug 08; 307(4):855-60. PMID: 12878189.
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    161. Jambal P, Masterson S, Nesterova A, Bouchard R, Bergman B, Hutton JC, Boxer LM, Reusch JE, Pugazhenthi S. Cytokine-mediated down-regulation of the transcription factor cAMP-response element-binding protein in pancreatic beta-cells. J Biol Chem. 2003 Jun 20; 278(25):23055-65. PMID: 12679364.
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    162. Pugazhenthi S, Nesterova A, Jambal P, Audesirk G, Kern M, Cabell L, Eves E, Rosner MR, Boxer LM, Reusch JE. Oxidative stress-mediated down-regulation of bcl-2 promoter in hippocampal neurons. J Neurochem. 2003 Mar; 84(5):982-96. PMID: 12603823.
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    163. Reusch JE, Gadsby R. Thiazolidinedione therapy: the benefits of aggressive and early use in type 2 diabetes. Diabetes Technol Ther. 2003; 5(4):685-93. PMID: 14511423.
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    164. Regensteiner JG, Popylisen S, Bauer TA, Lindenfeld J, Gill E, Smith S, Oliver-Pickett CK, Reusch JE, Weil JV. Oral L-arginine and vitamins E and C improve endothelial function in women with type 2 diabetes. Vasc Med. 2003; 8(3):169-75. PMID: 14989557.
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    165. Reusch JE. Current concepts in insulin resistance, type 2 diabetes mellitus, and the metabolic syndrome. Am J Cardiol. 2002 Sep 05; 90(5A):19G-26G. PMID: 12231075.
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    166. Watson PA, Vinson C, Nesterova A, Reusch JE. Content and activity of cAMP response element-binding protein regulate platelet-derived growth factor receptor-alpha content in vascular smooth muscles. Endocrinology. 2002 Aug; 143(8):2922-9. PMID: 12130557.
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    167. Eckel RH, Wassef M, Chait A, Sobel B, Barrett E, King G, Lopes-Virella M, Reusch J, Ruderman N, Steiner G, Vlassara H. Prevention Conference VI: Diabetes and Cardiovascular Disease: Writing Group II: pathogenesis of atherosclerosis in diabetes. Circulation. 2002 May 07; 105(18):e138-43. PMID: 11994264.
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    168. Brandenburg SL, Reusch JE, Felder KK, Nelson-Wong E, Lindenfeld J, Manco-Johnson M, Regensteiner JG. Impaired fibrinolysis in premenopausal women and age-matched men with Type 2 diabetes mellitus: a pilot study. J Investig Med. 2002 Mar; 50(2):110-5. PMID: 11930948.
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    169. Reusch JE, Klemm DJ. Inhibition of cAMP-response element-binding protein activity decreases protein kinase B/Akt expression in 3T3-L1 adipocytes and induces apoptosis. J Biol Chem. 2002 Jan 11; 277(2):1426-32. PMID: 11694510.
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    170. Watson PA, Nesterova A, Burant CF, Klemm DJ, Reusch JE. Diabetes-related changes in cAMP response element-binding protein content enhance smooth muscle cell proliferation and migration. J Biol Chem. 2001 Dec 07; 276(49):46142-50. PMID: 11560925.
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    171. Klemm DJ, Watson PA, Frid MG, Dempsey EC, Schaack J, Colton LA, Nesterova A, Stenmark KR, Reusch JE. cAMP response element-binding protein content is a molecular determinant of smooth muscle cell proliferation and migration. J Biol Chem. 2001 Dec 07; 276(49):46132-41. PMID: 11560924.
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    172. Klemm DJ, Leitner JW, Watson P, Nesterova A, Reusch JE, Goalstone ML, Draznin B. Insulin-induced adipocyte differentiation. Activation of CREB rescues adipogenesis from the arrest caused by inhibition of prenylation. J Biol Chem. 2001 Jul 27; 276(30):28430-5. PMID: 11375992.
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    173. Pugazhenthi S, Nesterova A, Sable C, Heidenreich KA, Boxer LM, Heasley LE, Reusch JE. Akt/protein kinase B up-regulates Bcl-2 expression through cAMP-response element-binding protein. J Biol Chem. 2000 Apr 14; 275(15):10761-6. PMID: 10753867.
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    174. Reusch JE, Colton LA, Klemm DJ. CREB activation induces adipogenesis in 3T3-L1 cells. Mol Cell Biol. 2000 Feb; 20(3):1008-20. PMID: 10629058.
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    175. Brandenburg SL, Reusch JE, Bauer TA, Jeffers BW, Hiatt WR, Regensteiner JG. Effects of exercise training on oxygen uptake kinetic responses in women with type 2 diabetes. Diabetes Care. 1999 Oct; 22(10):1640-6. PMID: 10526728.
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    176. Pugazhenthi S, Miller E, Sable C, Young P, Heidenreich KA, Boxer LM, Reusch JE. Insulin-like growth factor-I induces bcl-2 promoter through the transcription factor cAMP-response element-binding protein. J Biol Chem. 1999 Sep 24; 274(39):27529-35. PMID: 10488088.
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    177. Reusch JE, Klemm DJ. Nutrition and fat cell differentiation. Endocrinology. 1999 Jul; 140(7):2935-7. PMID: 10385383.
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    178. Pugazhenthi S, Boras T, O'Connor D, Meintzer MK, Heidenreich KA, Reusch JE. Insulin-like growth factor I-mediated activation of the transcription factor cAMP response element-binding protein in PC12 cells. Involvement of p38 mitogen-activated protein kinase-mediated pathway. J Biol Chem. 1999 Jan 29; 274(5):2829-37. PMID: 9915817.
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    179. Regensteiner JG, Bauer TA, Reusch JE, Brandenburg SL, Sippel JM, Vogelsong AM, Smith S, Wolfel EE, Eckel RH, Hiatt WR. Abnormal oxygen uptake kinetic responses in women with type II diabetes mellitus. J Appl Physiol (1985). 1998 Jul; 85(1):310-7. PMID: 9655791.
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    180. Reusch JE. Focus on insulin resistance in type 2 diabetes: therapeutic implications. Diabetes Educ. 1998 Mar-Apr; 24(2):188-93. PMID: 9555358.
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    181. Klemm DJ, Roesler WJ, Boras T, Colton LA, Felder K, Reusch JE. Insulin stimulates cAMP-response element binding protein activity in HepG2 and 3T3-L1 cell lines. J Biol Chem. 1998 Jan 09; 273(2):917-23. PMID: 9422750.
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    182. Carel K, DePaolo D, Reusch JE, Leitner JW, Draznin B. Reduced phosphorylation of mitogen-activated protein kinase kinase in response to insulin in cells with truncated C-terminal domain of insulin receptor. Endocrinology. 1996 Jun; 137(6):2362-6. PMID: 8641187.
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    183. DePaolo D, Reusch JE, Carel K, Bhuripanyo P, Leitner JW, Draznin B. Functional interactions of phosphatidylinositol 3-kinase with GTPase-activating protein in 3T3-L1 adipocytes. Mol Cell Biol. 1996 Apr; 16(4):1450-7. PMID: 8657118.
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    184. Reusch JE. New directions in treating insulin resistance. Hosp Pract (1995). 1995 Sep 15; 30(9):9-10. PMID: 7559840.
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    185. Reusch JE, Hsieh P, Bhuripanyo P, Carel K, Leitner JW, Olefsky JM, Draznin B. Insulin inhibits nuclear phosphatase activity: requirement for the C-terminal domain of the insulin receptor. Endocrinology. 1995 Jun; 136(6):2464-9. PMID: 7750468.
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    186. Reusch JE, Bhuripanyo P, Carel K, Leitner JW, Hsieh P, DePaolo D, Draznin B. Differential requirement for p21ras activation in the metabolic signaling by insulin. J Biol Chem. 1995 Feb 03; 270(5):2036-40. PMID: 7836430.
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    187. Reusch JE, Hsieh P, Klemm D, Hoeffler J, Draznin B. Insulin inhibits dephosphorylation of adenosine 3',5'-monophosphate response element-binding protein/activating transcription factor-1: effect on nuclear phosphoserine phosphatase-2a. Endocrinology. 1994 Dec; 135(6):2418-22. PMID: 7988426.
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    188. Begum N, Leitner W, Reusch JE, Sussman KE, Draznin B. GLUT-4 phosphorylation and its intrinsic activity. Mechanism of Ca(2+)-induced inhibition of insulin-stimulated glucose transport. J Biol Chem. 1993 Feb 15; 268(5):3352-6. PMID: 8381427.
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    189. Reusch JE, Sussman KE, Draznin B. Inverse relationship between GLUT-4 phosphorylation and its intrinsic activity. J Biol Chem. 1993 Feb 15; 268(5):3348-51. PMID: 8429011.
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    190. Reusch JE, Kleinschmidt-DeMasters BK, Lillehei KO, Rappe D, Gutierrez-Hartmann A. Preoperative diagnosis of lymphocytic hypophysitis (adenohypophysitis) unresponsive to short course dexamethasone: case report. Neurosurgery. 1992 Feb; 30(2):268-72. PMID: 1545900.
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    191. Reusch JE, Begum N, Sussman KE, Draznin B. Regulation of GLUT-4 phosphorylation by intracellular calcium in adipocytes. Endocrinology. 1991 Dec; 129(6):3269-73. PMID: 1659526.
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    192. Roemeling RV, Olshefski R, Langevin T, Berestka J, Reusch JJ, Reusch JE, Lakatua D, Wick MR, Hrushesky WJ. Cisplatin chronotherapy and disulfiram rescue reduce toxicity without interfering with anticancer activity: animal findings and preliminary clinical experiences. Chronobiol Int. 1986; 3(1):55-64. PMID: 3677194.
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