 Acetylcholinesterase
"Acetylcholinesterase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme that catalyzes the hydrolysis of ACETYLCHOLINE to CHOLINE and acetate. In the CNS, this enzyme plays a role in the function of peripheral neuromuscular junctions. EC 3.1.1.7.
| Descriptor ID |
D000110
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| MeSH Number(s) |
D08.811.277.352.100.170.176
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Acetylcholinesterase".
Below are MeSH descriptors whose meaning is more specific than "Acetylcholinesterase".
This graph shows the total number of publications written about "Acetylcholinesterase" by people in this website by year, and whether "Acetylcholinesterase" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 1 | 0 | 1 | | 2003 | 1 | 0 | 1 | | 2016 | 0 | 1 | 1 | | 2021 | 0 | 1 | 1 | | 2022 | 1 | 0 | 1 |
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Below are the most recent publications written about "Acetylcholinesterase" by people in Profiles.
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Mineur YS, Mose TN, Vanopdenbosch L, Etherington IM, Ogbejesi C, Islam A, Pineda CM, Crouse RB, Zhou W, Thompson DC, Bentham MP, Picciotto MR. Hippocampal acetylcholine modulates stress-related behaviors independent of specific cholinergic inputs. Mol Psychiatry. 2022 03; 27(3):1829-1838.
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McGuire JR, Bester SM, Guelta MA, Cheung J, Langley C, Winemiller MD, Bae SY, Funk V, Myslinski JM, Pegan SD, Height JJ. Structural and Biochemical Insights into the Inhibition of Human Acetylcholinesterase by G-Series Nerve Agents and Subsequent Reactivation by HI-6. Chem Res Toxicol. 2021 03 15; 34(3):804-816.
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Olivos M, Correa C, De la Torre L. Current practice of rectal biopsies for the diagnosis of Hirschsprung's disease in Latin America: an international online survey. Pediatr Surg Int. 2021 Apr; 37(4):479-483.
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Bester SM, Adipietro KA, Funk VL, Myslinski JM, Keul ND, Cheung J, Wilder PT, Wood ZA, Weber DJ, Height JJ, Pegan SD. The structural and biochemical impacts of monomerizing human acetylcholinesterase. Protein Sci. 2019 06; 28(6):1106-1114.
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Bester SM, Guelta MA, Cheung J, Winemiller MD, Bae SY, Myslinski J, Pegan SD, Height JJ. Structural Insights of Stereospecific Inhibition of Human Acetylcholinesterase by VX and Subsequent Reactivation by HI-6. Chem Res Toxicol. 2018 12 17; 31(12):1405-1417.
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Vlasits AL, Morrie RD, Tran-Van-Minh A, Bleckert A, Gainer CF, DiGregorio DA, Feller MB. A Role for Synaptic Input Distribution in a Dendritic Computation of Motion Direction in the Retina. Neuron. 2016 Mar 16; 89(6):1317-1330.
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Carcoba LM, Orfila JE, Natividad LA, Torres OV, Pipkin JA, Ferree PL, Casta?eda E, Moss DE, O'Dell LE. Cholinergic transmission during nicotine withdrawal is influenced by age and pre-exposure to nicotine: implications for teenage smoking. Dev Neurosci. 2014; 36(3-4):347-55.
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Amitai G, Murata H, Andersen JD, Koepsel RR, Russell AJ. Decontamination of chemical and biological warfare agents with a single multi-functional material. Biomaterials. 2010 May; 31(15):4417-25.
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Larsen GL, Loader J, Nguyen DD, Fratelli C, Dakhama A, Colasurdo GN. Mechanisms determining cholinergic neural responses in airways of young and mature rabbits. Pediatr Pulmonol. 2004 Aug; 38(2):97-106.
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Ma T, Kramer RE, Baker RC, Fan LW, Ho IK. Effects of chronic dermal exposure to nonlethal doses of methyl parathion on brain regional acetylcholinesterase and muscarinic cholinergic receptors in female rats. J Neurosci Res. 2003 Jan 01; 71(1):138-45.
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