 Long Interspersed Nucleotide Elements
"Long Interspersed Nucleotide Elements" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Highly repeated sequences, 6K-8K base pairs in length, which contain RNA polymerase II promoters. They also have an open reading frame that is related to the reverse transcriptase of retroviruses but they do not contain LTRs (long terminal repeats). Copies of the LINE 1 (L1) family form about 15% of the human genome. The jockey elements of Drosophila are LINEs.
| Descriptor ID |
D020084
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| MeSH Number(s) |
G02.111.570.080.708.330.800.400 G05.360.080.708.330.800.400 G05.360.340.024.425.800.400
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| Concept/Terms |
Long Interspersed Nucleotide Elements- Long Interspersed Nucleotide Elements
- LINE Repeat Sequences
- LINE Repeat Sequence
- Repeat Sequence, LINE
- Repeat Sequences, LINE
- Sequence, LINE Repeat
- Sequences, LINE Repeat
- Long Interspersed DNA Sequence Elements
LINE-1 Elements- LINE-1 Elements
- Element, LINE-1
- Elements, LINE-1
- LINE 1 Elements
- LINE-1 Element
- L1 Elements
- Element, L1
- Elements, L1
- L1 Element
Jockey Elements- Jockey Elements
- Element, Jockey
- Elements, Jockey
- Jockey Element
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Below are MeSH descriptors whose meaning is more general than "Long Interspersed Nucleotide Elements".
Below are MeSH descriptors whose meaning is more specific than "Long Interspersed Nucleotide Elements".
This graph shows the total number of publications written about "Long Interspersed Nucleotide Elements" by people in this website by year, and whether "Long Interspersed Nucleotide Elements" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 0 | 1 | 1 | | 2002 | 1 | 0 | 1 | | 2003 | 1 | 0 | 1 | | 2005 | 1 | 0 | 1 | | 2006 | 3 | 0 | 3 | | 2007 | 1 | 0 | 1 | | 2008 | 2 | 1 | 3 | | 2009 | 1 | 0 | 1 | | 2010 | 1 | 0 | 1 | | 2011 | 2 | 1 | 3 | | 2012 | 1 | 0 | 1 | | 2014 | 1 | 1 | 2 | | 2016 | 2 | 0 | 2 | | 2018 | 1 | 0 | 1 |
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Below are the most recent publications written about "Long Interspersed Nucleotide Elements" by people in Profiles.
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Martin SL. On the move. Elife. 2018 02 21; 7.
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Meyer TJ, Held U, Nevonen KA, Klawitter S, Pirzer T, Carbone L, Schumann GG. The Flow of the Gibbon LAVA Element Is Facilitated by the LINE-1 Retrotransposition Machinery. Genome Biol Evol. 2016 10 30; 8(10):3209-3225.
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Criscione SW, Theodosakis N, Micevic G, Cornish TC, Burns KH, Neretti N, Rodic N. Genome-wide characterization of human L1 antisense promoter-driven transcripts. BMC Genomics. 2016 06 14; 17:463.
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Malki S, van der Heijden GW, O'Donnell KA, Martin SL, Bortvin A. A role for retrotransposon LINE-1 in fetal oocyte attrition in mice. Dev Cell. 2014 Jun 09; 29(5):521-533.
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White TE, Brandariz-Nuñez A, Valle-Casuso JC, Knowlton C, Kim B, Sawyer SL, Diaz-Griffero F. Effects of human SAMHD1 polymorphisms on HIV-1 susceptibility. Virology. 2014 Jul; 460-461:34-44.
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Peddigari S, Li PW, Rabe JL, Martin SL. hnRNPL and nucleolin bind LINE-1 RNA and function as host factors to modulate retrotransposition. Nucleic Acids Res. 2013 Jan 07; 41(1):575-85.
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de Koning AP, Gu W, Castoe TA, Batzer MA, Pollock DD. Repetitive elements may comprise over two-thirds of the human genome. PLoS Genet. 2011 Dec; 7(12):e1002384.
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Januszyk K, Fleissner MR, Atchabahian L, Shieh FK, Altenbach C, Martin SL, Guo F, Hubbell WL, Clubb RT. Site-directed spin labeling electron paramagnetic resonance study of the ORF1 protein from a mouse L1 retrotransposon. Protein Sci. 2011 Jul; 20(7):1231-43.
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Evans JD, Peddigari S, Chaurasiya KR, Williams MC, Martin SL. Paired mutations abolish and restore the balanced annealing and melting activities of ORF1p that are required for LINE-1 retrotransposition. Nucleic Acids Res. 2011 Jul; 39(13):5611-21.
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Martin SL. Nucleic acid chaperone properties of ORF1p from the non-LTR retrotransposon, LINE-1. RNA Biol. 2010 Nov-Dec; 7(6):706-11.
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