 Cyclooxygenase 2
"Cyclooxygenase 2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An inducibly-expressed subtype of prostaglandin-endoperoxide synthase. It plays an important role in many cellular processes and INFLAMMATION. It is the target of COX2 INHIBITORS.
| Descriptor ID |
D051546
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| MeSH Number(s) |
D08.811.600.720.750
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| Concept/Terms |
Cyclooxygenase 2- Cyclooxygenase 2
- Cyclo-Oxygenase II
- Cyclo Oxygenase II
- PTGS2
- PGHS-2
- Prostaglandin H Synthase-2
- Prostaglandin H Synthase 2
- COX-2 Prostaglandin Synthase
- COX 2 Prostaglandin Synthase
- Prostaglandin Synthase, COX-2
- Synthase, COX-2 Prostaglandin
- Cyclooxygenase-2
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Below are MeSH descriptors whose meaning is more general than "Cyclooxygenase 2".
Below are MeSH descriptors whose meaning is more specific than "Cyclooxygenase 2".
This graph shows the total number of publications written about "Cyclooxygenase 2" by people in this website by year, and whether "Cyclooxygenase 2" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 3 | 3 | | 1998 | 0 | 2 | 2 | | 1999 | 0 | 2 | 2 | | 2000 | 0 | 4 | 4 | | 2001 | 0 | 3 | 3 | | 2002 | 0 | 5 | 5 | | 2003 | 0 | 8 | 8 | | 2004 | 0 | 8 | 8 | | 2005 | 0 | 4 | 4 | | 2006 | 5 | 3 | 8 | | 2007 | 4 | 5 | 9 | | 2008 | 3 | 4 | 7 | | 2009 | 3 | 5 | 8 | | 2010 | 0 | 7 | 7 | | 2011 | 4 | 3 | 7 | | 2012 | 1 | 3 | 4 | | 2013 | 0 | 3 | 3 | | 2014 | 2 | 4 | 6 | | 2015 | 1 | 2 | 3 | | 2016 | 2 | 5 | 7 | | 2017 | 0 | 5 | 5 | | 2018 | 1 | 0 | 1 | | 2019 | 1 | 5 | 6 | | 2020 | 0 | 2 | 2 | | 2021 | 0 | 2 | 2 |
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Below are the most recent publications written about "Cyclooxygenase 2" by people in Profiles.
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Goswami DG, Mishra N, Kant R, Agarwal C, Croutch CR, Enzenauer RW, Petrash MJ, Tewari-Singh N, Agarwal R. Pathophysiology and inflammatory biomarkers of sulfur mustard-induced corneal injury in rabbits. PLoS One. 2021; 16(10):e0258503.
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Marentette JO, Anderson CC, Prutton KM, Jennings EQ, Rauniyar AK, Galligan JJ, Roede JR. Trisomy 21 impairs PGE2 production in dermal fibroblasts. Prostaglandins Other Lipid Mediat. 2021 04; 153:106524.
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Borges VF, Lyons TR, Germain D, Schedin P. Postpartum Involution and Cancer: An Opportunity for Targeted Breast Cancer Prevention and Treatments? Cancer Res. 2020 05 01; 80(9):1790-1798.
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Tarullo SE, Hill RC, Hansen KC, Behbod F, Borges VF, Nelson AC, Lyons TR. Postpartum breast cancer progression is driven by semaphorin 7a-mediated invasion and survival. Oncogene. 2020 03; 39(13):2772-2785.
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Goswami DG, Kant R, Ammar DA, Agarwal C, Gomez J, Agarwal R, Saba LM, Fritz KS, Tewari-Singh N. Toxic consequences and oxidative protein carbonylation from chloropicrin exposure in human corneal epithelial cells. Toxicol Lett. 2020 Apr 01; 322:1-11.
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Wyatt GL, Crump LS, Young CM, Wessells VM, McQueen CM, Wall SW, Gustafson TL, Fan YY, Chapkin RS, Porter WW, Lyons TR. Cross-talk between SIM2s and NF?B regulates cyclooxygenase 2 expression in breast cancer. Breast Cancer Res. 2019 11 29; 21(1):131.
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Peng Y, Zhang X, Zhang T, Grace PM, Li H, Wang Y, Li H, Chen H, Watkins LR, Hutchinson MR, Yin H, Wang X. Lovastatin inhibits Toll-like receptor 4 signaling in microglia by targeting its co-receptor myeloid differentiation protein 2 and attenuates neuropathic pain. Brain Behav Immun. 2019 11; 82:432-444.
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Goswami DG, Kant R, Ammar DA, Kumar D, Enzenauer RW, Petrash JM, Tewari-Singh N, Agarwal R. Acute corneal injury in rabbits following nitrogen mustard ocular exposure. Exp Mol Pathol. 2019 10; 110:104275.
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Siegrist KJ, Romo D, Upham BL, Armstrong M, Quinn K, Vanderlinden L, Osgood RS, Velmurugan K, Elie M, Manke J, Reinhold D, Reisdorph N, Saba L, Bauer AK. Early Mechanistic Events Induced by Low Molecular Weight Polycyclic Aromatic Hydrocarbons in Mouse Lung Epithelial Cells: A Role for Eicosanoid Signaling. Toxicol Sci. 2019 05 01; 169(1):180-193.
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Romagnolo DF, Donovan MG, Doetschman TC, Selmin OI. n-6 Linoleic Acid Induces Epigenetics Alterations Associated with Colonic Inflammation and Cancer. Nutrients. 2019 Jan 15; 11(1).
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