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Joseph Hippensteel

TitleAssistant Professor
InstitutionUniversity of Colorado Denver - Anschutz Medical Campus
DepartmentSOM-MED

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Wang Z, Benicky J, Mukherjee P, Laing J, Xu Y, Pagadala V, Wu S, Hippensteel JA, Goldman R, Liu J. Editor's Choice Development of a method to measure the activity of heparan sulfate 6-endosulfatase for biological research. Glycobiology. 2025 Feb 28; 35(4). PMID: 40044126.
      View in: PubMed
    2. Sallee CJ, Maddux AB, Hippensteel JA, Markovic D, Oshima K, Schwingshackl A, Mourani PM, Schmidt EP, Sapru A. CIRCULATING HEPARAN SULFATE PROFILES IN PEDIATRIC ACUTE RESPIRATORY DISTRESS SYNDROME. Shock. 2024 Oct 01; 62(4):496-504. PMID: 39331799.
      View in: PubMed
    3. Andonian BJ, Hippensteel JA, Abuabara K, Boyle EM, Colbert JF, Devinney MJ, Faye AS, Kochar B, Lee J, Litke R, Nair D, Sattui SE, Sheshadri A, Sherman AN, Singh N, Zhang Y, LaHue SC. Inflammation and aging-related disease: A transdisciplinary inflammaging framework. Geroscience. 2025 Feb; 47(1):515-542. PMID: 39352664.
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    4. Palakshappa JA, Batt JAE, Bodine SC, Connolly BA, Doles J, Falvey JR, Ferrante LE, Files DC, Harhay MO, Harrell K, Hippensteel JA, Iwashyna TJ, Jackson JC, Lane-Fall MB, Monje M, Moss M, Needham DM, Semler MW, Lahiri S, Larsson L, Sevin CM, Sharshar T, Singer B, Stevens T, Taylor SP, Gomez CR, Zhou G, Girard TD, Hough CL. Tackling Brain and Muscle Dysfunction in Acute Respiratory Distress Syndrome Survivors: NHLBI Workshop Report. Am J Respir Crit Care Med. 2024 06 01; 209(11):1304-1313. PMID: 38477657.
      View in: PubMed
    5. Hippensteel JA, Aggarwal NR, Mikkelsen ME. A New Era in Critical Care Trials: Linking ICU Practice to Long-Term Outcomes. Am J Respir Crit Care Med. 2024 04 01; 209(7):782-784. PMID: 38387023.
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    6. Katsandres SC, Hall J, Danielson K, Sakr S, Dean SG, Carlbom DJ, Wurfel MM, Bhatraju PK, Hippensteel JA, Schmidt EP, Oshima K, Counts CR, Sayre MR, Henning DJ, Johnson NJ. Inflammation, endothelial injury, and the acute respiratory distress syndrome after out-of-hospital cardiac arrest. Resusc Plus. 2024 Mar; 17:100590. PMID: 38463638.
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    7. Oshima K, Siddiqui N, Orfila JE, Carter D, Laing J, Han X, Zakharevich I, Iozzo RV, Ghasabyan A, Moore H, Zhang F, Linhardt RJ, Moore EE, Quillinan N, Schmidt EP, Herson PS, Hippensteel JA. A role for decorin in improving motor deficits after traumatic brain injury. Matrix Biol. 2024 Jan; 125:88-99. PMID: 38135163.
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    8. Sallee CJ, Hippensteel JA, Miller KR, Oshima K, Pham AT, Richter RP, Belperio J, Sierra YL, Schwingshackl A, Mourani PM, Schmidt EP, Sapru A, Maddux AB. Endothelial Glycocalyx Degradation Patterns in Sepsis-Associated Pediatric Acute Respiratory Distress Syndrome: A Single Center Retrospective Observational Study. J Intensive Care Med. 2024 03; 39(3):277-287. PMID: 37670670.
      View in: PubMed
    9. Colbert JF, Kirsch JM, Erzen CL, Langou?t-Astri? CJ, Thompson GE, McMurtry SA, Kofonow JM, Robertson CE, Kovacs EJ, Sullivan RC, Hippensteel JA, Sawant NV, De Nisco NJ, McCollister BD, Schwartz RS, Horswill AR, Frank DN, Duerkop BA, Schmidt EP. Aging-Associated Augmentation of Gut Microbiome Virulence Capability Drives Sepsis Severity. mBio. 2023 06 27; 14(3):e0005223. PMID: 37102874.
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    10. Vasunilashorn SM, Lunardi N, Newman JC, Crosby G, Acker L, Abel T, Bhatnagar S, Cunningham C, de Cabo R, Dugan L, Hippensteel JA, Ishizawa Y, Lahiri S, Marcantonio ER, Xie Z, Inouye SK, Terrando N, Eckenhoff RG. Preclinical and translational models for delirium: Recommendations for future research from the NIDUS delirium network. Alzheimers Dement. 2023 05; 19(5):2150-2174. PMID: 36799408.
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    11. Rockstrom M, Balaban E, Fakhri S, Peterson RA, Jin Y, Jolley SE, Erlandson KM, Hippensteel JA. Predictors of adverse outcomes in aged patients critically ill with COVID-19: a retrospective study. J Investig Med. 2023 04; 71(4):315-320. PMID: 36655809.
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    12. Colbert JF, Kirsch JM, Erzen CL, Langou?t-Astri? CJ, Thompson GE, McMurtry SA, Kofonow JM, Robertson CE, Kovacs EJ, Sullivan RC, Hippensteel JA, Sawant NV, De Nisco NJ, McCollister BD, Schwartz RS, Horswill AR, Frank DN, Duerkop BA, Schmidt EP. Aging-associated augmentation of gut microbiome virulence capability drives sepsis severity. bioRxiv. 2023 Jan 11. PMID: 36711447.
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    13. Siddiqui N, Oshima K, Hippensteel JA. Proteoglycans and glycosaminoglycans in central nervous system injury. Am J Physiol Cell Physiol. 2022 07 01; 323(1):C46-C55. PMID: 35613357.
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    14. Sullivan RC, Rockstrom MD, Schmidt EP, Hippensteel JA. Endothelial glycocalyx degradation during sepsis: Causes and consequences. Matrix Biol Plus. 2021 Dec; 12:100094. PMID: 34917925.
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    15. Bai X, Hippensteel J, Leavitt A, Maloney JP, Beckham D, Garcia C, Li Q, Freed BM, Ordway D, Sandhaus RA, Chan ED. Hypothesis: Alpha-1-antitrypsin is a promising treatment option for COVID-19. Med Hypotheses. 2021 Jan; 146:110394. PMID: 33239231.
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    16. Hippensteel JA, Burnham EL, Jolley SE. Prevalence of venous thromboembolism in critically ill patients with COVID-19. Br J Haematol. 2020 08; 190(3):e134-e137. PMID: 32484907.
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    17. Hippensteel JA, LaRiviere WB, Colbert JF, Langou?t-Astri? CJ, Schmidt EP. Heparin as a therapy for COVID-19: current evidence and future possibilities. Am J Physiol Lung Cell Mol Physiol. 2020 08 01; 319(2):L211-L217. PMID: 32519894.
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    18. Hippensteel JA, Uchimido R, Tyler PD, Burke RC, Han X, Zhang F, McMurtry SA, Colbert JF, Lindsell CJ, Angus DC, Kellum JA, Yealy DM, Linhardt RJ, Shapiro NI, Schmidt EP. Intravenous fluid resuscitation is associated with septic endothelial glycocalyx degradation. Crit Care. 2019 07 23; 23(1):259. PMID: 31337421.
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    19. Kwiecinski JM, Crosby HA, Valotteau C, Hippensteel JA, Nayak MK, Chauhan AK, Schmidt EP, Dufr?ne YF, Horswill AR. Staphylococcus aureus adhesion in endovascular infections is controlled by the ArlRS-MgrA signaling cascade. PLoS Pathog. 2019 05; 15(5):e1007800. PMID: 31116795.
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    20. Zhang X, Han X, Xia K, Xu Y, Yang Y, Oshima K, Haeger SM, Perez MJ, McMurtry SA, Hippensteel JA, Ford JA, Herson PS, Liu J, Schmidt EP, Linhardt RJ. Circulating heparin oligosaccharides rapidly target the hippocampus in sepsis, potentially impacting cognitive functions. Proc Natl Acad Sci U S A. 2019 05 07; 116(19):9208-9213. PMID: 31010931.
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    21. Hippensteel JA, Anderson BJ, Orfila JE, McMurtry SA, Dietz RM, Su G, Ford JA, Oshima K, Yang Y, Zhang F, Han X, Yu Y, Liu J, Linhardt RJ, Meyer NJ, Herson PS, Schmidt EP. Circulating heparan sulfate fragments mediate septic cognitive dysfunction. J Clin Invest. 2019 04 01; 129(4):1779-1784. PMID: 30720464.
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    22. Hippensteel JA, Shapiro NI, Schmidt EP. Challenging Dogma: The Value of Bolus Fluids in the Early Resuscitation of Hyperdynamic Sepsis. Am J Respir Crit Care Med. 2018 10 15; 198(8):981-983. PMID: 29940124.
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    23. Hippensteel JA, Schmidt EP. Sequestering Damage-associated Molecular Patterns in Critical Illness. A Novel Homeostatic Role for the Erythrocyte. Am J Respir Crit Care Med. 2018 02 15; 197(4):416-418. PMID: 29120664.
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    24. Oshima K, Haeger SM, Hippensteel JA, Herson PS, Schmidt EP. More than a biomarker: the systemic consequences of heparan sulfate fragments released during endothelial surface layer degradation (2017 Grover Conference Series). Pulm Circ. 2018 Jan-Mar; 8(1):2045893217745786. PMID: 29199903.
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    25. Yang Y, Hippensteel JA, Schmidt EP. Intravital Microscopy in the Mouse Lung. Methods Mol Biol. 2018; 1809:331-339. PMID: 29987798.
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    26. Hippensteel J, Heidecker B, Goldschlager N. ECG quiz. Ta waves mimicking infero-lateral ST elevation during an exercise stress test. J Electrocardiol. 2014 Sep-Oct; 47(5):748-9. PMID: 25295338.
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    27. Thongpang S, Richner TJ, Brodnick SK, Schendel A, Kim J, Wilson JA, Hippensteel J, Krugner-Higby L, Moran D, Ahmed AS, Neimann D, Sillay K, Williams JC. A micro-electrocorticography platform and deployment strategies for chronic BCI applications. Clin EEG Neurosci. 2011 Oct; 42(4):259-65. PMID: 22208124.
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    28. Blake AJ, Rodgers FC, Bassuener A, Hippensteel JA, Pearce TM, Pearce TR, Zarnowska ED, Pearce RA, Williams JC. A microfluidic brain slice perfusion chamber for multisite recording using penetrating electrodes. J Neurosci Methods. 2010 May 30; 189(1):5-13. PMID: 20219536.
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    29. Williams JC, Hippensteel JA, Dilgen J, Shain W, Kipke DR. Complex impedance spectroscopy for monitoring tissue responses to inserted neural implants. J Neural Eng. 2007 Dec; 4(4):410-23. PMID: 18057508.
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