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Benjamin Steven Frank

TitleAsst Professor
InstitutionUniversity of Colorado Denver - Anschutz Medical Campus
DepartmentSOM-PEDS

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Davidson JA, Robison J, Khailova L, Frank BS, Jaggers J, Ing RJ, Lawson S, Iguidbashian J, Ali E, Treece A, Soranno DE, Osorio-Lujan S, Klawitter J. Metabolomic profiling demonstrates evidence for kidney and urine metabolic dysregulation in a piglet model of cardiac surgery-induced acute kidney injury. Am J Physiol Renal Physiol. 2022 07 01; 323(1):F20-F32. PMID: 35532069.
      View in: PubMed
    2. Frank BS, Khailova L, Silveira L, Mitchell MB, Morgan GJ, DiMaria MV, Davidson JA. Increased Circulating Endothelin 1 Is Associated With Postoperative Hypoxemia in Infants With Single-Ventricle Heart Disease Undergoing Superior Cavopulmonary Anastomosis. J Am Heart Assoc. 2022 03 15; 11(6):e024007. PMID: 35243904.
      View in: PubMed
    3. Schäfer M, Frank BS, Ivy DD, Mitchell MB, Collins KK, Jone PN, von Alvensleben JC. Repolarization Dispersion Is Associated With Diastolic Electromechanical Discoordination in Children With Pulmonary Arterial Hypertension. J Am Heart Assoc. 2022 03 15; 11(6):e024787. PMID: 35229614.
      View in: PubMed
    4. Issapour A, Frank B, Crook S, Hite MD, Dorn ML, Rosenzweig EB, Ivy DD, Krishnan US. Safety and tolerability of combination therapy with ambrisentan and tadalafil for the treatment of pulmonary arterial hypertension in children: Real-world experience. Pediatr Pulmonol. 2022 03; 57(3):724-733. PMID: 34921523.
      View in: PubMed
    5. Schäfer M, Frank BS, Grady RM, Eghtesady P, Mitchell MB, Jaggers J, Ivy DD. Monitoring and evaluation of the surgical Potts shunt physiology using 4-dimensional flow magnetic resonance imaging. J Thorac Cardiovasc Surg. 2022 08; 164(2):331-341. PMID: 34872760.
      View in: PubMed
    6. Cooney SJ, Klawitter J, Khailova L, Robison J, Jaggers J, Ing RJ, Lawson S, Frank BS, Lujan SO, Davidson JA. Regional lung metabolic profile in a piglet model of cardiopulmonary bypass with circulatory arrest. Metabolomics. 2021 09 22; 17(10):89. PMID: 34553313.
      View in: PubMed
    7. Bloom JL, Frank B, Weinman JP, Galambos C, O'Leary ST, Liptzin DR, Fuhlbrigge RC. Diffuse alveolar hemorrhage in children with trisomy 21. Pediatr Rheumatol Online J. 2021 Jul 17; 19(1):114. PMID: 34273981.
      View in: PubMed
    8. Schäfer M, Ivy DD, Nguyen K, Boncella K, Frank BS, Morgan GJ, Miller-Reed K, Truong U, Colvin K, Yeager ME. Metalloproteinases and their inhibitors are associated with pulmonary arterial stiffness and ventricular function in pediatric pulmonary hypertension. Am J Physiol Heart Circ Physiol. 2021 07 01; 321(1):H242-H252. PMID: 34085841.
      View in: PubMed
    9. Oganesyan A, Hoffner-Heinike A, Barker AJ, Frank BS, Ivy DD, Hunter KS, Mitchell MB, Humphries SM, Fenster BE, Schäfer M. Abnormal pulmonary flow is associated with impaired right ventricular coupling in patients with COPD. Int J Cardiovasc Imaging. 2021 Oct; 37(10):3039-3048. PMID: 34021434.
      View in: PubMed
    10. Davidson JA, Frank BS, Urban TT, Twite M, Jaggers J, Khailova L, Klawitter J. Serum metabolic profile of postoperative acute kidney injury following infant cardiac surgery with cardiopulmonary bypass. Pediatr Nephrol. 2021 10; 36(10):3259-3269. PMID: 33954809.
      View in: PubMed
    11. Schäfer M, Frank BS, Ivy DD, Abman SH, Stenmark KR, Mitchell MB, Browne LP, Barker AJ, Hunter KS, Kheyfets V, Miller-Reed K, Ing R, Morgan GJ, Truong U. Short-Term Effects of Inhaled Nitric Oxide on Right Ventricular Flow Hemodynamics by 4-Dimensional-Flow Magnetic Resonance Imaging in Children With Pulmonary Arterial Hypertension. J Am Heart Assoc. 2021 04 20; 10(8):e020548. PMID: 33821682.
      View in: PubMed
    12. Frank BS, Schäfer M, Thomas TM, Ivy DD, Jone PN. Longitudinal assessment of right atrial conduit fraction provides additional insight to predict adverse events in pediatric pulmonary hypertension. Int J Cardiol. 2021 04 15; 329:242-245. PMID: 33400972.
      View in: PubMed
    13. Ivy D, Frank BS. Update on pediatric pulmonary arterial hypertension. Curr Opin Cardiol. 2021 01; 36(1):67-79. PMID: 33136663.
      View in: PubMed
    14. Frank BS, Khailova L, Silveira L, Mitchell MB, Morgan GJ, Hsieh EWY, DiMaria MV, Twite M, Klawitter J, Davidson JA. Proteomic profiling identifies key differences between inter-stage infants with single ventricle heart disease and healthy controls. Transl Res. 2021 03; 229:24-37. PMID: 33045409.
      View in: PubMed
    15. Frank BS, Ivy DD. Pediatric Pulmonary Arterial Hypertension. Pediatr Clin North Am. 2020 10; 67(5):903-921. PMID: 32888689.
      View in: PubMed
    16. Das BB, Frank B, Ivy D. Segmental Pulmonary Hypertension in Children with Congenital Heart Disease. Medicina (Kaunas). 2020 Sep 24; 56(10). PMID: 32987636.
      View in: PubMed
    17. Pagano E, Frank B, Jaggers J, Twite M, Urban TT, Klawitter J, Davidson J. Alterations in Metabolites Associated with Hypoxemia in Neonates and Infants with Congenital Heart Disease. Congenit Heart Dis. 2020 Sep 07; 15(4):251-265. PMID: 34413893.
      View in: PubMed
    18. Sabapathy D, Klawitter J, Silveira L, Khailova L, Mitchell MB, Morgan GJ, DiMaria MV, Twite M, Frank BS, Davidson JA. Activation of kynurenine pathway of tryptophan metabolism after infant cardiac surgery with cardiopulmonary bypass: a prospective cohort study. Metabolomics. 2020 09 05; 16(9):93. PMID: 32889608.
      View in: PubMed
    19. Schäfer M, Frank BS, Jacobsen R, Rausch CM, Mitchell MB, Jaggers J, Stone ML, Morgan GJ, Browne LP, Barker AJ, Hunter KS, Ivy DD, Younoszai A, Di Maria MV. Patients with Fontan circulation have abnormal aortic wave propagation patterns: A wave intensity analysis study. Int J Cardiol. 2021 01 01; 322:158-167. PMID: 32853667.
      View in: PubMed
    20. Schäfer M, Bjornstad P, Frank BS, Baumgartner A, Truong U, Enge D, von Alvensleben JC, Mitchell MB, Ivy DD, Barker AJ, Reusch JEB, Nadeau KJ. Frequency of Reduced Left Ventricular Contractile Efficiency and Discoordinated Myocardial Relaxation in Patients Aged 16 to 21 Years With Type 1 Diabetes Mellitus (from the Emerald Study). Am J Cardiol. 2020 08 01; 128:45-53. PMID: 32650923.
      View in: PubMed
    21. Frank BS, Schafer M, Thomas TM, Haxel C, Ivy DD, Jone PN. Right Atrial Conduit Phase Emptying Predicts Risk of Adverse Events in Pediatric Pulmonary Arterial Hypertension. J Am Soc Echocardiogr. 2020 08; 33(8):1006-1013. PMID: 32336608.
      View in: PubMed
    22. Schäfer M, Frank BS, Humphries SM, Hunter KS, Carmody KL, Jacobsen R, Mitchell MB, Jaggers J, Stone ML, Morgan GJ, Barker AJ, Browne LP, Ivy DD, Younoszai A, Di Maria MV. Flow profile characteristics in Fontan circulation are associated with the single ventricle dilation and function: principal component analysis study. Am J Physiol Heart Circ Physiol. 2020 05 01; 318(5):H1032-H1040. PMID: 32167782.
      View in: PubMed
    23. Frank BS, Schäfer M, Douwes JM, Ivy DD, Abman SH, Davidson JA, Burzlaff S, Mitchell MB, Morgan GJ, Browne LP, Barker AJ, Truong U, von Alvensleben JC. Novel measures of left ventricular electromechanical discoordination predict clinical outcomes in children with pulmonary arterial hypertension. Am J Physiol Heart Circ Physiol. 2020 02 01; 318(2):H401-H412. PMID: 31858817.
      View in: PubMed
    24. Frank BS, Schäfer M, Grenolds A, Ivy DD, Abman SH, Darst JR. Acute Vasoreactivity Testing during Cardiac Catheterization of Neonates with Bronchopulmonary Dysplasia-Associated Pulmonary Hypertension. J Pediatr. 2019 05; 208:127-133. PMID: 30871795.
      View in: PubMed
    25. Davidson JA, Urban TT, Tong S, Maddux A, Hill G, Frank BS, Watson JD, Jaggers J, Simões EAF, Wischmeyer P. Alkaline Phosphatase Activity and Endotoxemia After Infant Cardiothoracic Surgery. Shock. 2019 03; 51(3):328-336. PMID: 29664834.
      View in: PubMed
    26. Frank BS, Runciman M, Manning WA, Ivy DD, Abman SH, Howley L. Pulmonary Hypertension Secondary to Scurvy in a Developmentally Typical Child. J Pediatr. 2019 May; 208:291-291.e2. PMID: 30738657.
      View in: PubMed
    27. Frank BS, Urban TT, Lewis K, Tong S, Cassidy C, Mitchell MB, Nichols CS, Davidson JA. Circulating biomarkers of left ventricular hypertrophy in pediatric coarctation of the aorta. Congenit Heart Dis. 2019 May; 14(3):446-453. PMID: 30650250.
      View in: PubMed
    28. Davidson JA, Pfeifer Z, Frank B, Tong S, Urban TT, Wischmeyer PA, Mourani P, Landeck B, Christians U, Klawitter J. Metabolomic Fingerprinting of Infants Undergoing Cardiopulmonary Bypass: Changes in Metabolic Pathways and Association With Mortality and Cardiac Intensive Care Unit Length of Stay. J Am Heart Assoc. 2018 12 18; 7(24):e010711. PMID: 30561257.
      View in: PubMed
    29. Schäfer M, Frank BS, Ivy DD, Wilson N, Morgan GJ, Barker AJ, Browne LP, Mitchell MB, Truong U. Close look at the Potts shunt flow hemodynamics in a patient with severe pulmonary hypertension: 4D-flow MRI evaluation. J Magn Reson Imaging. 2019 06; 49(6):1800-1802. PMID: 30451346.
      View in: PubMed
    30. Frank BS, Ivy DD. Diagnosis, Evaluation and Treatment of Pulmonary Arterial Hypertension in Children. Children (Basel). 2018 Mar 23; 5(4). PMID: 29570688.
      View in: PubMed
    31. Schäfer M, Collins KK, Browne LP, Ivy DD, Abman S, Friesen R, Frank B, Fonseca B, DiMaria M, Hunter KS, Truong U, von Alvensleben JC. Effect of electrical dyssynchrony on left and right ventricular mechanics in children with pulmonary arterial hypertension. J Heart Lung Transplant. 2018 07; 37(7):870-878. PMID: 29496397.
      View in: PubMed
    32. Frank BS, Urban TT, Tong S, Cassidy C, Mitchell MB, Nichols CS, Davidson JA. Endothelin-1 activation in pediatric patients undergoing surgical coarctation of the aorta repair. World J Cardiol. 2017 Dec 26; 9(12):822-829. PMID: 29317988.
      View in: PubMed
    33. Frank B, Davidson J, Tong S, Martin B, Heizer H, Anderson MS, Glode MP, Dominguez SR, Jone PN. Myocardial Strain and Strain Rate in Kawasaki Disease: Range, Recovery, and Relationship to Systemic Inflammation/Coronary Artery Dilation. J Clin Exp Cardiolog. 2016 Apr; 7(4). PMID: 27182455.
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    34. Thornton RH, Frank BS, Covey AM, Maybody M, Solomon SB, Getrajdman GI, Brown KT. Catheter-free survival after primary percutaneous stenting of malignant bile duct obstruction. AJR Am J Roentgenol. 2011 Sep; 197(3):W514-8. PMID: 21862781.
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    35. Frank BS, Toth PB, Wells WK, McFall CR, Cromwell ML, Hilbert SL, Lofland GK, Hopkins RA. Determining cell seeding dosages for tissue engineering human pulmonary valves. J Surg Res. 2012 May 01; 174(1):39-47. PMID: 21345451.
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    36. Chubinskaya S, Frank BS, Michalska M, Kumar B, Merrihew CA, Thonar EJ, Lenz ME, Otten L, Rueger DC, Block JA. Osteogenic protein 1 in synovial fluid from patients with rheumatoid arthritis or osteoarthritis: relationship with disease and levels of hyaluronan and antigenic keratan sulfate. Arthritis Res Ther. 2006; 8(3):R73. PMID: 16646979.
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    37. Frank BS, Vardar D, Chishti AH, McKnight CJ. The NMR structure of dematin headpiece reveals a dynamic loop that is conformationally altered upon phosphorylation at a distal site. J Biol Chem. 2004 Feb 27; 279(9):7909-16. PMID: 14660664.
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    38. Vardar D, Chishti AH, Frank BS, Luna EJ, Noegel AA, Oh SW, Schleicher M, McKnight CJ. Villin-type headpiece domains show a wide range of F-actin-binding affinities. Cell Motil Cytoskeleton. 2002 May; 52(1):9-21. PMID: 11977079.
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    39. Frank BS, Vardar D, Buckley DA, McKnight CJ. The role of aromatic residues in the hydrophobic core of the villin headpiece subdomain. Protein Sci. 2002 Mar; 11(3):680-7. PMID: 11847290.
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    40. Vardar D, Buckley DA, Frank BS, McKnight CJ. NMR structure of an F-actin-binding "headpiece" motif from villin. J Mol Biol. 1999 Dec 17; 294(5):1299-310. PMID: 10600386.
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    41. Frank BS, Lewis RJ. Experience with intubated patients does not affect the accidental extubation rate in pediatric intensive care units and intensive care nurseries. Pediatr Pulmonol. 1997 Jun; 23(6):424-8. PMID: 9220524.
      View in: PubMed
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