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Duc Minh Ha

TitleAffiliate - VA
InstitutionUniversity of Colorado Denver - Anschutz Medical Campus
ORCID ORCID Icon0000-0002-3003-9438 Additional info

    Collapse Biography 
    Collapse education and training
    University of Colorado School of Medicine, Aurora, ColoradoM.D. 2011Medicine
    Cleveland Clinic, Cleveland, OhioResidency2014Internal Medicine
    University of California San Diego, La Jolla, CaliforniaFellowship2017Pulmonary and Critical Care Medicine
    University of California San Diego, La Jolla, CaliforniaM.A.S.2018Masters in Clinical Research and Postdoctoral Research Fellowship
    Collapse awards and honors
    2004 - 2005NIH Undergraduate Scholarship Program, University of Denver
    2008 - 2008Achievement Rewards for College Scientists, University of Colorado Anschutz School of Medicine
    2009 - 2009Robert Felix Award, Department of Psychiatry, University of Colorado Anschutz School of Medicine
    2016 - 2018NIH/NCI Loan Repayment Program, University of California San Diego
    2017 - 2018American Cancer Society Individual Postdoctoral Fellowship Award, University of California San Diego
    2021 - 2023American Lung Association Lung Cancer Discovery Award, Institute for Health Research, Kaiser Permanente Colorado
    2022 - 2027VA Career Development Award Rehabilitation & Research Development, Rocky Mountain Regional Veterans Affairs Medical Center

    Collapse Overview 
    Collapse overview
    Dr. Ha is a Staff Pulmonologist and Critical Care Medicine (ICU) Physician at the Rocky Mountain Regional Veterans Affairs Medical Center and Assistant Professor in the Division of Pulmonary Sciences and Critical Care Medicine at the University of Colorado Anschutz Medical Campus. His research focuses on survivorship care following diagnosis and treatment of lung cancer, particularly of stage I-III lung cancer with curative intent. He has led and completed quantitative research projects that characterized symptom burden, functional impairments, and health-related quality of life challenges among Veteran lung cancer survivors following curative intent therapy, as well as qualitative research to gain in-depth understandings of their views and preferences for rehabilitation and telerehabilitation. Informed by his and others’ research in this field, Dr. Ha and his team have proposed a conceptual model of a vicious cycle of “dyspnea-inactivity” and downward health spiral that needs to be promptly disrupted to reduce symptom burden, improve function, enhance health-related quality of life, decrease health care use, and prolong survival following curative intent therapy of lung cancer. To this end, he and his team have completed a pilot randomized trial ( NCT05059132) to evaluate telemedicine-based inspiratory muscle training and walking promotion to reverse this postulated vicious cycle of “dyspnea-inactivity” and found that this targeted intervention was feasible, acceptable, safe, and could reduce dyspnea, improve physical activity, and enhance health-related quality of life (PMID 37656252).

    Dr. Ha’s long-term goals are to evaluate patient-centered survivorship care, including through targeted rehabilitation and patient-centered trials, to improve the physical and psychosocial function, enhance quality of life, promote well-being, and longevity for Veterans with lung cancer following curative intent therapy. His research has been supported by the US National Institutes of Health/National Cancer Institute (L30 CA208950), American Cancer Society (130760-PF-17-020-01-CPPB), American Lung Association (LCD 820773), and US Department of Veterans Affairs Rehabilitation Research & Development Program (IK2RX003661).

    Collapse Research 
    Collapse research activities and funding
    IK2RX003661     (HA, DUC M.)Apr 1, 2022 - Mar 31, 2027
    Telerehabilitation for Veteran Lung Cancer Survivors Following Curative Intent Therapy
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    List All   |   Timeline
    1. Ha DM, Comer A, Dollar B, Bedoy R, Ford M, Gozansky WS, Zeng C, Arch JJ, Leach HJ, Malhotra A, Prochazka AV, Keith RL, Boxer RS. Telemedicine-based inspiratory muscle training and walking promotion with lung cancer survivors following curative intent therapy: a parallel-group pilot randomized trial. Support Care Cancer. 2023 Sep 01; 31(9):546. PMID: 37656252.
      View in: PubMed
    2. Ha DM, Nunnery MA, Klocko RP, Haverhals LM, Bekelman DB, New ML, Randhawa SK, Stevens-Lapsley JE, Studts JL, Prochazka AV, Keith RL. Lung cancer survivors' views on telerehabilitation following curative intent therapy: a formative qualitative study. BMJ Open. 2023 06 23; 13(6):e073251. PMID: 37355268.
      View in: PubMed
    3. Bade BC, Faiz SA, Ha DM, Tan M, Barton-Burke M, Cheville AL, Escalante CP, Gozal D, Granger CL, Presley CJ, Smith SM, Chamberlaine DM, Long JM, Malone DJ, Pirl WF, Robinson HL, Yasufuku K, Rivera MP. Cancer-related Fatigue in Lung Cancer: A Research Agenda: An Official American Thoracic Society Research Statement. Am J Respir Crit Care Med. 2023 03 01; 207(5):e6-e28. PMID: 36856560.
      View in: PubMed
    4. Ha DM, Deng LR, Lange AV, Swigris JJ, Bekelman DB. Reliability, Validity, and Responsiveness of the DEG, a Three-Item Dyspnea Measure. J Gen Intern Med. 2022 08; 37(10):2541-2547. PMID: 34981344.
      View in: PubMed
    5. Ha DM, Prochazka AV, Bekelman DB, Stevens-Lapsley JE, Studts JL, Keith RL. Modifiable factors associated with health-related quality of life among lung cancer survivors following curative intent therapy. Lung Cancer. 2022 01; 163:42-50. PMID: 34896804.
      View in: PubMed
    6. Ha DM, Zeng C, Chan ED, Gray M, Mazzone PJ, Samet JM, Steiner JF. Association of Exercise Behavior with Overall Survival in Stage I-IIIA Lung Cancer. Ann Am Thorac Soc. 2021 06; 18(6):1034-1042. PMID: 33326358.
      View in: PubMed
    7. Ha DM, Prochazka AV, Bekelman DB, Stevens-Lapsley JE, Chan ED, Keith RL. Association of Leisure-Time Physical Activity With Health-Related Quality of Life Among US Lung Cancer Survivors. JNCI Cancer Spectr. 2021 02; 5(1). PMID: 35075444.
      View in: PubMed
    8. Ha D, Ries AL. Characterization of Dyspnea in Veteran Lung Cancer Survivors Following Curative-Intent Therapy. J Cardiopulm Rehabil Prev. 2020 03; 40(2):120-127. PMID: 31592931.
      View in: PubMed
    9. Ha D, Kerr J, Ries AL, Fuster MM, Lippman SM, Murphy JD. A Model-Based Cost-Effectiveness Analysis of an Exercise Program for Lung Cancer Survivors After Curative-Intent Treatment. Am J Phys Med Rehabil. 2020 03; 99(3):233-240. PMID: 31361623.
      View in: PubMed
    10. Ha D, Ries AL, Lippman SM, Fuster MM. Effects of curative-intent lung cancer therapy on functional exercise capacity and patient-reported outcomes. Support Care Cancer. 2020 Oct; 28(10):4707-4720. PMID: 31965306.
      View in: PubMed
    11. Ha D, Malhotra A, Ries AL, O'Neal WT, Fuster MM. Heart rate variability and heart rate recovery in lung cancer survivors eligible for long-term cure. Respir Physiol Neurobiol. 2019 11; 269:103264. PMID: 31376471.
      View in: PubMed
    12. Liu D, Wen H, He J, Gao S, Li S, Liu L, He J, Huang Y, Xu S, Mao W, Tan Q, Chen C, Li X, Zhang Z, Jiang G, Xu L, Zhang L, Fu J, Li H, Wang Q, Tan L, Li D, Zhou Q, Fu X, Jiang Z, Chen H, Fang W, Zhang X, Li Y, Tong T, Yu Z, Liu Y, Zhi X, Yan T, Zhang X, Brunelli A, Salati M, Phan K, Hida Y, Venuta F, Choi JH, Papagiannopoulos K, Ha D, Novoa N. Society for Translational Medicine Expert Consensus on the preoperative assessment of circulatory and cardiac functions and criteria for the assessment of risk factors in patients with lung cancer. J Thorac Dis. 2018 Sep; 10(9):5545-5549. PMID: 30416805.
      View in: PubMed
    13. Ha D, Ries AL, Montgrain P, Vaida F, Sheinkman S, Fuster MM. Time to treatment and survival in veterans with lung cancer eligible for curative intent therapy. Respir Med. 2018 08; 141:172-179. PMID: 30053964.
      View in: PubMed
    14. Ha D, Ries AL, Mazzone PJ, Lippman SM, Fuster MM. Exercise capacity and cancer-specific quality of life following curative intent treatment of stage I-IIIA lung cancer. Support Care Cancer. 2018 Jul; 26(7):2459-2469. PMID: 29429006.
      View in: PubMed
    15. Ha D, Mazzone PJ, Ries AL, Malhotra A, Fuster M. The Utility of Exercise Testing in Patients with Lung Cancer. J Thorac Oncol. 2016 09; 11(9):1397-410. PMID: 27156441.
      View in: PubMed
    16. Ha D, Fuster M, Ries AL, Wagner PD, Mazzone PJ. Heart Rate Recovery as a Preoperative Test of Perioperative Complication Risk. Ann Thorac Surg. 2015 Nov; 100(5):1954-62. PMID: 26410158.
      View in: PubMed
    17. Ha D, Stephans K, Choi H, Zell K, Wang XF, Minai OA, Raymond DP, Videtic G, Mazzone PJ. Heart rate recovery and survival in patients undergoing stereotactic body radiotherapy for treatment of early-stage lung cancer. J Radiosurg SBRT. 2015; 3(3):193-201. PMID: 29296402.
      View in: PubMed
    18. Ha D, Choi H, Chevalier C, Zell K, Wang XF, Mazzone PJ. Survival in patients with metachronous second primary lung cancer. Ann Am Thorac Soc. 2015 Jan; 12(1):79-84. PMID: 25494009.
      View in: PubMed
    19. Ha D, Choi H, Zell K, Raymond DP, Stephans K, Wang XF, Videtic G, McCarthy K, Minai OA, Mazzone PJ. Association of impaired heart rate recovery with cardiopulmonary complications after lung cancer resection surgery. J Thorac Cardiovasc Surg. 2015 Apr; 149(4):1168-73.e3. PMID: 25583106.
      View in: PubMed
    20. Ha D, Choi H, Almeida FA, Arrossi A, Brainard J, Cicenia J, Farver C, Gildea T, Machuzak MS, Mazzone P. Histologic and molecular characterization of lung cancer with tissue obtained by electromagnetic navigation bronchoscopy. J Bronchology Interv Pulmonol. 2013 Jan; 20(1):10-5. PMID: 23328135.
      View in: PubMed
    21. Anaganti S, Hansen JK, Ha D, Hahn Y, Chertov O, Pastan I, Bera TK. Non-AUG translational initiation of a short CAPC transcript generating protein isoform. Biochem Biophys Res Commun. 2009 Mar 13; 380(3):508-13. PMID: 19250639.
      View in: PubMed
    22. Bera TK, Saint Fleur A, Ha D, Yamada M, Lee Y, Lee B, Hahn Y, Kaufman DS, Pera M, Pastan I. Selective POTE paralogs on chromosome 2 are expressed in human embryonic stem cells. Stem Cells Dev. 2008 Apr; 17(2):325-32. PMID: 18447647.
      View in: PubMed
    23. Lee Y, Ise T, Ha D, Saint Fleur A, Hahn Y, Liu XF, Nagata S, Lee B, Bera TK, Pastan I. Evolution and expression of chimeric POTE-actin genes in the human genome. Proc Natl Acad Sci U S A. 2006 Nov 21; 103(47):17885-90. PMID: 17101985.
      View in: PubMed
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