Crohn Disease
"Crohn Disease" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A chronic transmural inflammation that may involve any part of the DIGESTIVE TRACT from MOUTH to ANUS, mostly found in the ILEUM, the CECUM, and the COLON. In Crohn disease, the inflammation, extending through the intestinal wall from the MUCOSA to the serosa, is characteristically asymmetric and segmental. Epithelioid GRANULOMAS may be seen in some patients.
Descriptor ID |
D003424
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MeSH Number(s) |
C06.405.205.731.500 C06.405.469.432.500
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Concept/Terms |
Crohn Disease- Crohn Disease
- Crohn's Enteritis
- Regional Enteritis
- Crohn's Disease
- Crohns Disease
- Inflammatory Bowel Disease 1
Ileitis, Terminal- Ileitis, Terminal
- Terminal Ileitis
- Ileitis, Regional
- Regional Ileitides
- Regional Ileitis
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Below are MeSH descriptors whose meaning is more general than "Crohn Disease".
Below are MeSH descriptors whose meaning is more specific than "Crohn Disease".
This graph shows the total number of publications written about "Crohn Disease" by people in this website by year, and whether "Crohn Disease" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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1994 | 1 | 0 | 1 | 1996 | 0 | 1 | 1 | 1997 | 0 | 2 | 2 | 1998 | 1 | 0 | 1 | 1999 | 1 | 0 | 1 | 2002 | 1 | 1 | 2 | 2003 | 1 | 0 | 1 | 2004 | 1 | 1 | 2 | 2005 | 1 | 1 | 2 | 2006 | 1 | 2 | 3 | 2007 | 2 | 0 | 2 | 2008 | 3 | 1 | 4 | 2009 | 4 | 1 | 5 | 2010 | 2 | 1 | 3 | 2011 | 2 | 0 | 2 | 2012 | 2 | 2 | 4 | 2013 | 4 | 2 | 6 | 2014 | 6 | 0 | 6 | 2015 | 5 | 2 | 7 | 2016 | 7 | 2 | 9 | 2017 | 7 | 2 | 9 | 2018 | 2 | 1 | 3 | 2019 | 6 | 1 | 7 | 2020 | 12 | 0 | 12 | 2021 | 14 | 3 | 17 | 2022 | 16 | 0 | 16 | 2023 | 10 | 0 | 10 | 2024 | 2 | 0 | 2 |
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Below are the most recent publications written about "Crohn Disease" by people in Profiles.
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Smith ES, Chen J, Pan Y, Mahtani P, Lukin D, Ahmed W, Longman R, Burakoff R, Scherl E, Battat R. The Relationship Between the Endoscopic Healing Index, Fecal Calprotectin, and Magnetic Resonance Enterography in Crohn's Disease. J Clin Gastroenterol. 2024 Jul 01; 58(6):607-613.
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Bachour SP, Click BH. Clinical Update on the Prevention and Management of Postoperative Crohn's Disease Recurrence. Curr Gastroenterol Rep. 2024 Feb; 26(2):41-52.
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Alula KM, Dowdell AS, LeBere B, Lee JS, Levens CL, Kuhn KA, Kaipparettu BA, Thompson WE, Blumberg RS, Colgan SP, Theiss AL. Interplay of gut microbiota and host epithelial mitochondrial dysfunction is necessary for the development of spontaneous intestinal inflammation in mice. Microbiome. 2023 11 17; 11(1):256.
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Shah RS, Bachour S, Joseph A, Xiao H, Lyu R, Syed H, Li T, Pothula S, Vinaithirthan V, Ali AH, Contreras S, Hu JH, Barnes EL, Axelrad JE, Holubar SD, Regueiro M, Cohen BL, Click BH. Real-World Surgical and Endoscopic Recurrence Based on Risk Profiles and Prophylaxis Utilization in Postoperative Crohn's Disease. Clin Gastroenterol Hepatol. 2024 Apr; 22(4):847-857.e12.
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Li T, Click B, Bachour S, Sachs M, Barnes EL, Cohen BL, Contreras S, Axelrad J. Suboptimal Guideline Adherence and Biomarker Underutilization in Monitoring of Post-operative Crohn's Disease. Dig Dis Sci. 2023 09; 68(9):3596-3604.
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Garg R, Aggarwal M, Mohammed A, Achkar JP, Lashner B, Philpott J, Cohen B, Qazi T, Rieder F, Regueiro M, Click B. Real-world effectiveness and safety of ustekinumab and vedolizumab in elderly patients with Crohn's disease. Indian J Gastroenterol. 2023 10; 42(5):718-723.
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Bachour SP, Khan MZ, Shah RS, Joseph A, Syed H, Ali AH, Rieder F, Holubar SD, Barnes EL, Axelrad J, Regueiro M, Cohen BL, Click BH. Anastomotic Configuration and Temporary Diverting Ileostomy Do Not Increase Risk of Anastomotic Stricture in Postoperative Crohn's Disease. Am J Gastroenterol. 2023 12 01; 118(12):2212-2219.
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Sleiman J, Patel M, Khan MZ, Falloon K, Cohen B, Click B, Khanna U, Fernandez AP, Rieder F. Sweet Syndrome Associated with Active Inflammatory Bowel Disease: A Case Series of a Rare Extra-intestinal Manifestation. Dig Dis Sci. 2023 09; 68(9):3562-3568.
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Alula KM, Theiss AL. Autophagy in Crohn's Disease: Converging on Dysfunctional Innate Immunity. Cells. 2023 07 04; 12(13).
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Axelrad JE, Li T, Bachour SP, Nakamura TI, Shah R, Sachs MC, Chang S, Hudesman DP, Holubar SD, Lightner AL, Barnes EL, Cohen BL, Rieder F, Esen E, Remzi F, Regueiro M, Click B. Early Initiation of Antitumor Necrosis Factor Therapy Reduces Postoperative Recurrence of Crohn's Disease Following Ileocecal Resection. Inflamm Bowel Dis. 2023 06 01; 29(6):888-897.
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