Optic Atrophy
"Optic Atrophy" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Atrophy of the optic disk which may be congenital or acquired. This condition indicates a deficiency in the number of nerve fibers which arise in the RETINA and converge to form the OPTIC DISK; OPTIC NERVE; OPTIC CHIASM; and optic tracts. GLAUCOMA; ISCHEMIA; inflammation, a chronic elevation of intracranial pressure, toxins, optic nerve compression, and inherited conditions (see OPTIC ATROPHIES, HEREDITARY) are relatively common causes of this condition.
Descriptor ID |
D009896
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MeSH Number(s) |
C10.292.700.225 C11.640.451
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Optic Atrophy".
Below are MeSH descriptors whose meaning is more specific than "Optic Atrophy".
This graph shows the total number of publications written about "Optic Atrophy" by people in this website by year, and whether "Optic Atrophy" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2003 | 0 | 1 | 1 | 2004 | 0 | 1 | 1 | 2011 | 1 | 0 | 1 | 2015 | 0 | 1 | 1 | 2016 | 1 | 0 | 1 | 2017 | 0 | 1 | 1 | 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Optic Atrophy" by people in Profiles.
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Jones AA, Morgenstern JL, Mandair D, Pedler MG, Olson JL. EFFICACY OF INTRAVITREAL AFLIBERCEPT INJECTIONS IN THE TREATMENT OF IDIOPATHIC RETINAL VASCULITIS, ANEURYSMS, AND NEURORETINITIS SYNDROME. Retin Cases Brief Rep. 2022 Jul 01; 16(4):515-519.
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Kaiwar C, Zimmermann MT, Ferber MJ, Niu Z, Urrutia RA, Klee EW, Babovic-Vuksanovic D. Novel NR2F1 variants likely disrupt DNA binding: molecular modeling in two cases, review of published cases, genotype-phenotype correlation, and phenotypic expansion of the Bosch-Boonstra-Schaaf optic atrophy syndrome. Cold Spring Harb Mol Case Stud. 2017 Nov; 3(6).
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Heimer G, Ker?t?r JM, Riley LG, Balasubramaniam S, Eyal E, Pietik?inen LP, Hiltunen JK, Marek-Yagel D, Hamada J, Gregory A, Rogers C, Hogarth P, Nance MA, Shalva N, Veber A, Tzadok M, Nissenkorn A, Tonduti D, Renaldo F, Kraoua I, Panteghini C, Valletta L, Garavaglia B, Cowley MJ, Gayevskiy V, Roscioli T, Silberstein JM, Hoffmann C, Raas-Rothschild A, Tiranti V, Anikster Y, Christodoulou J, Kastaniotis AJ, Ben-Zeev B, Hayflick SJ. MECR Mutations Cause Childhood-Onset Dystonia and Optic Atrophy, a Mitochondrial Fatty Acid Synthesis Disorder. Am J Hum Genet. 2016 Dec 01; 99(6):1229-1244.
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Weisfeld-Adams JD, McCourt EA, Diaz GA, Oliver SC. Ocular disease in the cobalamin C defect: a review of the literature and a suggested framework for clinical surveillance. Mol Genet Metab. 2015 Apr; 114(4):537-46.
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Bucca BC, Klingensmith G, Bennett JL. Wolfram Syndrome: a rare optic neuropathy in youth with type 1 diabetes. Optom Vis Sci. 2011 Nov; 88(11):E1383-90.
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Oliver SC, Bennett JL. Genetic disorders and the optic nerve: a clinical survey. Ophthalmol Clin North Am. 2004 Sep; 17(3):435-45, vii.
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Davidson RS, Brandt JD, Mannis MJ. Intraocular pressure-induced interlamellar keratitis after LASIK surgery. J Glaucoma. 2003 Feb; 12(1):23-6.
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Bathon JM, Moreland LW, DiBartolomeo AG. Inflammatory central nervous system involvement in rheumatoid arthritis. Semin Arthritis Rheum. 1989 May; 18(4):258-66.
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Osei K, Weber PA, Falko JM. Coexistence of diabetes mellitus, optic atrophy, and sensorineural deafness: case report. Ann Ophthalmol. 1986 May; 18(5):196-8.
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Kincaid MC, Green WR, Fine SL, Ferris FL, Patz A. An ocular clinicopathologic correlative study of six patients from the Diabetic Retinopathy Study. Retina. 1983; 3(3):218-38.
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