Aldehyde Oxidase
"Aldehyde Oxidase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An aldehyde oxidoreductase expressed predominantly in the LIVER; LUNGS; and KIDNEY. It catalyzes the oxidation of a variety of organic aldehydes and N-heterocyclic compounds to CARBOXYLIC ACIDS, and also oxidizes quinoline and pyridine derivatives. The enzyme utilizes molybdenum cofactor and FAD as cofactors.
Descriptor ID |
D042931
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MeSH Number(s) |
D08.811.682.657.163.311
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Aldehyde Oxidase".
Below are MeSH descriptors whose meaning is more specific than "Aldehyde Oxidase".
This graph shows the total number of publications written about "Aldehyde Oxidase" by people in this website by year, and whether "Aldehyde Oxidase" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1995 | 0 | 1 | 1 | 1996 | 0 | 1 | 1 | 1999 | 0 | 1 | 1 |
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Below are the most recent publications written about "Aldehyde Oxidase" by people in Profiles.
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Wright RM, Riley MG, Weigel LK, Ginger LA, Costantino DA, McManaman JL. Activation of the human aldehyde oxidase (hAOX1) promoter by tandem cooperative Sp1/Sp3 binding sites: identification of complex architecture in the hAOX upstream DNA that includes a proximal promoter, distal activation sites, and a silencer element. DNA Cell Biol. 2000 Aug; 19(8):459-74.
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Wright RM, Clayton DA, Riley MG, McManaman JL, Repine JE. cDNA cloning, sequencing, and characterization of male and female rat liver aldehyde oxidase (rAOX1). Differences in redox status may distinguish male and female forms of hepatic APX. J Biol Chem. 1999 Feb 05; 274(6):3878-86.
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McManaman JL, Shellman V, Wright RM, Repine JE. Purification of rat liver xanthine oxidase and xanthine dehydrogenase by affinity chromatography on benzamidine-sepharose. Arch Biochem Biophys. 1996 Aug 01; 332(1):135-41.
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Berger R, Mezey E, Clancy KP, Harta G, Wright RM, Repine JE, Brown RH, Brownstein M, Patterson D. Analysis of aldehyde oxidase and xanthine dehydrogenase/oxidase as possible candidate genes for autosomal recessive familial amyotrophic lateral sclerosis. Somat Cell Mol Genet. 1995 Mar; 21(2):121-31.
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