 Crotalid Venoms
"Crotalid Venoms" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Venoms from snakes of the subfamily Crotalinae or pit vipers, found mostly in the Americas. They include the rattlesnake, cottonmouth, fer-de-lance, bushmaster, and American copperhead. Their venoms contain nontoxic proteins, cardio-, hemo-, cyto-, and neurotoxins, and many enzymes, especially phospholipases A. Many of the toxins have been characterized.
| Descriptor ID |
D003435
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| MeSH Number(s) |
D20.888.850.960.200 D23.946.833.850.960.200
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| Concept/Terms |
Crotalid Venoms- Crotalid Venoms
- Venoms, Crotalid
- Pit Viper Venoms
- Venoms, Pit Viper
- Pit Viper Venom
- Venom, Pit Viper
- Viper Venom, Pit
- Crotalid Venom
- Venom, Crotalid
Rattlesnake Venoms- Rattlesnake Venoms
- Venoms, Rattlesnake
- Rattlesnake Venom
- Venom, Rattlesnake
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Below are MeSH descriptors whose meaning is more general than "Crotalid Venoms".
Below are MeSH descriptors whose meaning is more specific than "Crotalid Venoms".
This graph shows the total number of publications written about "Crotalid Venoms" by people in this website by year, and whether "Crotalid Venoms" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
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| 2004 | 4 | 0 | 4 | | 2009 | 1 | 1 | 2 | | 2010 | 1 | 1 | 2 | | 2011 | 0 | 2 | 2 | | 2013 | 2 | 0 | 2 | | 2015 | 1 | 0 | 1 | | 2016 | 0 | 1 | 1 | | 2017 | 2 | 0 | 2 | | 2018 | 2 | 0 | 2 | | 2019 | 2 | 0 | 2 | | 2020 | 1 | 1 | 2 | | 2021 | 1 | 0 | 1 | | 2022 | 1 | 0 | 1 | | 2023 | 3 | 0 | 3 | | 2024 | 2 | 0 | 2 | | 2025 | 3 | 0 | 3 |
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Below are the most recent publications written about "Crotalid Venoms" by people in Profiles.
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Kim C, Smith SN, Gopalan SS, Kerwin SR, Ballard K, Perry BW, Smith CF, Saviola AJ, Adams RH, Mackessy SP, Castoe TA. Unique physiological and regulatory activity drives divergent toxin and non-toxin gene expression in rattlesnake accessory venom glands. Toxicon. 2025 May; 259:108376.
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Ruha AM, Spyres MB, Culbreth R, Wolk B, Hoyte C, Campleman S. Systemic toxicity after rattlesnake envenomation in patients using angiotensin converting enzyme inhibitors: A North American Snakebite Registry study. Toxicon. 2025 Apr; 258:108292.
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Borja M, Casta?eda-Gayt?n G, Alag?n A, Strickland JL, Parkinson CL, Guti?rrez-Mart?nez A, Rodriguez-L?pez B, Zarzosa V, Lomonte B, Saviola AJ, Fern?ndez J, Smith CF, Hansen KC, P?rez-Robles A, Casta?eda-P?rez S, Hirst SR, Olvera-Rodr?guez F, Fern?ndez-Badillo L, Sigala J, Jones J, Monta?o-Ruvalcaba C, Ram?rez-Chaparro R, Margres MJ, Acosta-Campa?a G, Neri-Castro E. Venom variation and ontogenetic changes in the Crotalus molossus complex: Insights into composition, activities, and antivenom neutralization. Comp Biochem Physiol C Toxicol Pharmacol. 2025 Apr; 290:110129.
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Gopalan SS, Perry BW, Francioli YZ, Schield DR, Guss HD, Bernstein JM, Ballard K, Smith CF, Saviola AJ, Adams RH, Mackessy SP, Castoe TA. Diverse Gene Regulatory Mechanisms Alter Rattlesnake Venom Gene Expression at Fine Evolutionary Scales. Genome Biol Evol. 2024 Jul 03; 16(7).
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Smith CF, Modahl CM, Ceja Galindo D, Larson KY, Maroney SP, Bahrabadi L, Brandehoff NP, Perry BW, McCabe MC, Petras D, Lomonte B, Calvete JJ, Castoe TA, Mackessy SP, Hansen KC, Saviola AJ. Assessing Target Specificity of the Small Molecule Inhibitor MARIMASTAT to Snake Venom Toxins: A Novel Application of Thermal Proteome Profiling. Mol Cell Proteomics. 2024 Jun; 23(6):100779.
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Smith CF, Nikolakis ZL, Perry BW, Schield DR, Meik JM, Saviola AJ, Castoe TA, Parker J, Mackessy SP. The best of both worlds? Rattlesnake hybrid zones generate complex combinations of divergent venom phenotypes that retain high toxicity. Biochimie. 2023 Oct; 213:176-189.
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Smith CF, Nikolakis ZL, Ivey K, Perry BW, Schield DR, Balchan NR, Parker J, Hansen KC, Saviola AJ, Castoe TA, Mackessy SP. Snakes on a plain: biotic and abiotic factors determine venom compositional variation in a wide-ranging generalist rattlesnake. BMC Biol. 2023 06 06; 21(1):136.
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Grabowsky ER, Saviola AJ, Alvarado-D?az J, Mascare?as AQ, Hansen KC, Yates JR, Mackessy SP. Montane Rattlesnakes in M?xico: Venoms of Crotalus tancitarensis and Related Species within the Crotalus intermedius Group. Toxins (Basel). 2023 01 13; 15(1).
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Schield DR, Perry BW, Adams RH, Holding ML, Nikolakis ZL, Gopalan SS, Smith CF, Parker JM, Meik JM, DeGiorgio M, Mackessy SP, Castoe TA. The roles of balancing selection and recombination in the evolution of rattlesnake venom. Nat Ecol Evol. 2022 09; 6(9):1367-1380.
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Gopalan SS, Perry BW, Schield DR, Smith CF, Mackessy SP, Castoe TA. Origins, genomic structure and copy number variation of snake venom myotoxins. Toxicon. 2022 Sep; 216:92-106.
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