 Genes, Tumor Suppressor
"Genes, Tumor Suppressor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Genes that inhibit expression of the tumorigenic phenotype. They are normally involved in holding cellular growth in check. When tumor suppressor genes are inactivated or lost, a barrier to normal proliferation is removed and unregulated growth is possible.
| Descriptor ID |
D016147
|
| MeSH Number(s) |
G05.360.340.024.340.375.249 G05.360.340.024.340.415.400
|
| Concept/Terms |
Genes, Tumor Suppressor- Genes, Tumor Suppressor
- Gene, Tumor Suppressor
- Tumor Suppressor Gene
- Antioncogenes
- Antioncogene
- Emerogenes
- Emerogene
- Genes, Onco-Suppressor
- Gene, Onco-Suppressor
- Genes, Onco Suppressor
- Onco-Suppressor Gene
- Onco-Suppressor Genes
- Cancer Suppressor Genes
- Cancer Suppressor Gene
- Gene, Cancer Suppressor
- Suppressor Gene, Cancer
- Suppressor Genes, Cancer
- Oncogenes, Recessive
- Oncogene, Recessive
- Recessive Oncogene
- Recessive Oncogenes
- Anti-Oncogenes
- Anti Oncogenes
- Anti-Oncogene
- Tumor Suppressing Genes
- Gene, Tumor Suppressing
- Genes, Tumor Suppressing
- Tumor Suppressing Gene
- Genes, Cancer Suppressor
- Tumor Suppressor Genes
Metastasis Suppressor Genes- Metastasis Suppressor Genes
- Gene, Metastasis Suppressor
- Metastasis Suppressor Gene
- Suppressor Gene, Metastasis
- Suppressor Genes, Metastasis
- Genes, Metastasis Suppressor
Growth Suppressor Genes- Growth Suppressor Genes
- Gene, Growth Suppressor
- Growth Suppressor Gene
- Suppressor Gene, Growth
- Suppressor Genes, Growth
- Genes, Growth Suppressor
|
Below are MeSH descriptors whose meaning is more general than "Genes, Tumor Suppressor".
Below are MeSH descriptors whose meaning is more specific than "Genes, Tumor Suppressor".
- Genes, Tumor Suppressor
- Genes, APC
- Genes, BRCA1
- Genes, BRCA2
- Genes, DCC
- Genes, MCC
- Genes, Neurofibromatosis 1
- Genes, Neurofibromatosis 2
- Genes, p16
- Genes, p53
- Genes, Retinoblastoma
- Genes, Wilms Tumor
This graph shows the total number of publications written about "Genes, Tumor Suppressor" by people in this website by year, and whether "Genes, Tumor Suppressor" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1991 | 1 | 0 | 1 | | 1993 | 0 | 1 | 1 | | 1994 | 0 | 1 | 1 | | 1995 | 1 | 0 | 1 | | 1996 | 1 | 2 | 3 | | 1997 | 2 | 1 | 3 | | 1998 | 5 | 1 | 6 | | 1999 | 3 | 0 | 3 | | 2000 | 0 | 2 | 2 | | 2001 | 2 | 1 | 3 | | 2002 | 0 | 5 | 5 | | 2003 | 4 | 2 | 6 | | 2004 | 0 | 6 | 6 | | 2006 | 3 | 1 | 4 | | 2007 | 1 | 0 | 1 | | 2008 | 1 | 1 | 2 | | 2009 | 0 | 2 | 2 | | 2011 | 0 | 2 | 2 | | 2012 | 1 | 1 | 2 | | 2013 | 0 | 2 | 2 | | 2014 | 1 | 2 | 3 | | 2015 | 1 | 3 | 4 | | 2017 | 1 | 0 | 1 | | 2018 | 0 | 1 | 1 | | 2019 | 1 | 1 | 2 | | 2021 | 1 | 0 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "Genes, Tumor Suppressor" by people in Profiles.
-
Andrysik Z, Bender H, Galbraith MD, Espinosa JM. Multi-omics analysis reveals contextual tumor suppressive and oncogenic gene modules within the acute hypoxic response. Nat Commun. 2021 03 02; 12(1):1375.
-
McMahon M, Contreras A, Holm M, Uechi T, Forester CM, Pang X, Jackson C, Calvert ME, Chen B, Quigley DA, Luk JM, Kelley RK, Gordan JD, Gill RM, Blanchard SC, Ruggero D. A single H/ACA small nucleolar RNA mediates tumor suppression downstream of oncogenic RAS. Elife. 2019 09 03; 8.
-
Hernandez AL, Young CD, Wang JH, Wang XJ. Lessons learned from SMAD4 loss in squamous cell carcinomas. Mol Carcinog. 2019 09; 58(9):1648-1655.
-
Moon SH, Huang CH, Houlihan SL, Regunath K, Freed-Pastor WA, Morris JP, Tschaharganeh DF, Kastenhuber ER, Barsotti AM, Culp-Hill R, Xue W, Ho YJ, Baslan T, Li X, Mayle A, de Stanchina E, Zender L, Tong DR, D'Alessandro A, Lowe SW, Prives C. p53 Represses the Mevalonate Pathway to Mediate Tumor Suppression. Cell. 2019 01 24; 176(3):564-580.e19.
-
Kiseljak-Vassiliades K, Mills TS, Zhang Y, Xu M, Lillehei KO, Kleinschmidt-DeMasters BK, Wierman ME. Elucidating the Role of the Desmosome Protein p53 Apoptosis Effector Related to PMP-22 in Growth Hormone Tumors. Endocrinology. 2017 05 01; 158(5):1450-1460.
-
Pelish HE, Liau BB, Nitulescu II, Tangpeerachaikul A, Poss ZC, Da Silva DH, Caruso BT, Arefolov A, Fadeyi O, Christie AL, Du K, Banka D, Schneider EV, Jestel A, Zou G, Si C, Ebmeier CC, Bronson RT, Krivtsov AV, Myers AG, Kohl NE, Kung AL, Armstrong SA, Lemieux ME, Taatjes DJ, Shair MD. Mediator kinase inhibition further activates super-enhancer-associated genes in AML. Nature. 2015 Oct 08; 526(7572):273-276.
-
Hoelzl MA, Heby-Henricson K, Bilousova G, Rozell B, Kuiper RV, Kasper M, Toftgård R, Teglund S. Suppressor of Fused Plays an Important Role in Regulating Mesodermal Differentiation of Murine Embryonic Stem Cells In Vivo. Stem Cells Dev. 2015 Nov 01; 24(21):2547-60.
-
Kitamura H, Ozono E, Iwanaga R, Bradford AP, Okuno J, Shimizu E, Kurayoshi K, Kugawa K, Toh H, Ohtani K. Identification of novel target genes specifically activated by deregulated E2F in human normal fibroblasts. Genes Cells. 2015 Sep; 20(9):739-57.
-
Hensel J, Duex JE, Owens C, Dancik GM, Edwards MG, Frierson HF, Theodorescu D. Patient Mutation Directed shRNA Screen Uncovers Novel Bladder Tumor Growth Suppressors. Mol Cancer Res. 2015 Sep; 13(9):1306-15.
-
Lesko AC, Goss KH, Yang FF, Schwertner A, Hulur I, Onel K, Prosperi JR. The APC tumor suppressor is required for epithelial cell polarization and three-dimensional morphogenesis. Biochim Biophys Acta. 2015 Mar; 1853(3):711-23.
|
People  People who have written about this concept. _
Similar Concepts
People who have written about this concept.
_
Top Journals
Top journals in which articles about this concept have been published.
|