 Sepsis
"Sepsis" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Systemic inflammatory response syndrome with a proven or suspected infectious etiology. When sepsis is associated with organ dysfunction distant from the site of infection, it is called severe sepsis. When sepsis is accompanied by HYPOTENSION despite adequate fluid infusion, it is called SEPTIC SHOCK.
| Descriptor ID |
D018805
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| MeSH Number(s) |
C01.539.757 C23.550.470.790.500
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| Concept/Terms |
Pyemia- Pyemia
- Pyemias
- Pyohemia
- Pyohemias
- Pyaemia
- Pyaemias
Septicemia- Septicemia
- Septicemias
- Poisoning, Blood
- Blood Poisoning
- Blood Poisonings
- Poisonings, Blood
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Below are MeSH descriptors whose meaning is more general than "Sepsis".
Below are MeSH descriptors whose meaning is more specific than "Sepsis".
This graph shows the total number of publications written about "Sepsis" by people in this website by year, and whether "Sepsis" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 3 | 0 | 3 | | 1996 | 1 | 1 | 2 | | 1997 | 2 | 2 | 4 | | 1998 | 1 | 0 | 1 | | 1999 | 6 | 0 | 6 | | 2000 | 1 | 2 | 3 | | 2001 | 5 | 1 | 6 | | 2002 | 4 | 0 | 4 | | 2003 | 4 | 4 | 8 | | 2004 | 3 | 4 | 7 | | 2005 | 8 | 2 | 10 | | 2006 | 10 | 4 | 14 | | 2007 | 9 | 1 | 10 | | 2008 | 7 | 4 | 11 | | 2009 | 11 | 2 | 13 | | 2010 | 12 | 5 | 17 | | 2011 | 4 | 2 | 6 | | 2012 | 3 | 0 | 3 | | 2013 | 16 | 1 | 17 | | 2014 | 9 | 3 | 12 | | 2015 | 19 | 4 | 23 | | 2016 | 20 | 5 | 25 | | 2017 | 24 | 3 | 27 | | 2018 | 14 | 2 | 16 | | 2019 | 19 | 4 | 23 | | 2020 | 28 | 6 | 34 | | 2021 | 25 | 0 | 25 | | 2022 | 28 | 1 | 29 | | 2023 | 33 | 0 | 33 | | 2024 | 18 | 3 | 21 | | 2025 | 15 | 1 | 16 |
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Below are the most recent publications written about "Sepsis" by people in Profiles.
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Oshima K, Di Gravio C, Yan B, McMurtry SA, Burke R, Levoir LM, Kravitz MS, Stephenson D, Issaian A, Hansen KC, D'Alessandro A, Douglas IS, Self WH, Lindsell CJ, Schildcrout JS, Schmidt EP, Shapiro NI. Endothelial Glycocalyx Degradation in Sepsis: Analysis of the Crystalloid Liberal or Vasopressors Early Resuscitation in Sepsis (CLOVERS) Trial, a Multicenter, Phase 3, Randomized Trial. Ann Am Thorac Soc. 2025 Sep; 22(9):1382-1393.
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Kiernan E, Zelnick LR, Khader A, Coston TD, Bailey ZA, Speckmaier S, Lo JJ, Siew ED, Sathe NA, Kestenbaum BR, Himmelfarb J, Johnson NJ, Shapiro NI, Douglas IS, Hough CL, Bhatraju PK. Molecular Phenotyping of Sepsis and Differential Response to Fluid Resuscitation. Am J Respir Crit Care Med. 2025 Sep; 211(9):1681-1688.
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Munroe ES, Co IN, Douglas I, Hyzy R, Khan A, Nelson K, Park PK, Peltan ID, Rice TW, Seelye S, Self WH, Shapiro NI, Prescott HC. Peripheral Vasopressor Use in Early Sepsis-Induced Hypotension. JAMA Netw Open. 2025 Aug 01; 8(8):e2529148.
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Stanski NL, Zhang B, Ouyang J, Sanchez-Pinto LN, Faustino EVS, Rogerson CM, Hall MW, Weiss SL, Bennett TD, Standage SW, Goldstein SL, Liu KD. Derivation and Validation of Pediatric Sepsis-Associated Acute Kidney Injury Subphenotypes With Prognostic Relevance. Pediatr Crit Care Med. 2025 Sep 01; 26(9):e1084-e1095.
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Morgan RW, Reeder RW, Carcillo JA, Carpenter TC, Fitzgerald JC, Graham K, Kilbaugh TJ, Meert KL, Nadkarni VM, Palmer CA, Sharron MP, Weiss SL, Wolfe HA, Ahmed T, Bell MJ, Bishop R, Burns C, Diddle JW, Fink EL, Franzon D, Frazier AH, Friess SH, Hehir DA, Horvat CM, Huard LL, Maa T, McQuillen PS, Mourani PM, Naim MY, Pollack MM, Sapru A, Srivastava N, Yates AR, Berg RA, Sutton RM. Outcomes, Characteristics, and Physiology of In-Hospital Cardiac Arrest in Children With Sepsis. Crit Care Med. 2025 Aug 01; 53(8):e1529-e1541.
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Weissman GE, Hubbard RA, Himes BE, Goodman-O'Leary KL, Harhay MO, Ginestra JC, Kohn R, Admon AJ, Taylor SP, Halpern SD. Sepsis Prediction Models are Trained on Labels that Diverge from Clinician-Recommended Treatment Times. AMIA Annu Symp Proc. 2024; 2024:1215-1224.
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Green A, Patel S, Crabtree P, Patel D, Hoke A, Orozco RJ, Sangah G, Mercado A, Melchiorre N, Charron M, Chandel A, Puri N. The association of sepsis bundle compliance with mortality in patients with ICU-acquired sepsis: a cohort study. BMC Infect Dis. 2025 May 20; 25(1):723.
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Foulon N, Haeger SM, Okamura K, He Z, Park BD, Budnick IM, Madison D, Kennis M, Blaine R, Miyazaki M, Jalal DI, Griffin BR, Aftab M, Colbert JF, Faubel S. Procalcitonin levels in septic and nonseptic subjects with AKI and ESKD prior to and during continuous kidney replacement therapy (CKRT). Crit Care. 2025 Apr 30; 29(1):171.
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Rossetti SC, Dykes PC, Knaplund C, Cho S, Withall J, Lowenthal G, Albers D, Lee RY, Jia H, Bakken S, Kang MJ, Chang FY, Zhou L, Bates DW, Daramola T, Liu F, Schwartz-Dillard J, Tran M, Bokhari SMA, Thate J, Cato KD. Real-time surveillance system for patient deterioration: a pragmatic cluster-randomized controlled trial. Nat Med. 2025 Jun; 31(6):1895-1902.
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Patterson JK, Neuwahl S, Kirsch S, Moore JL, Tita ATN, Carlo WA, Lokangaka A, Tshefu A, Mwenechanya M, Chomba E, Kavi A, Metgud MC, Goudar SS, Derman RJ, Shivkumar P, Waikar M, Patel A, Hibberd PL, Nyongesa P, Esamai F, Ekhaguere OA, Bucher S, Jessani S, Tikmani SS, Saleem S, Wylie BJ, Goldenberg RL, Billah SM, Lennox R, Haque R, Petri WA, Mazariegos M, Krebs NF, Hemingway-Foday JJ, Babineau D, Koso-Thomas M, McClure EM, Bauserman M. Cost-effectiveness of intrapartum azithromycin to prevent maternal infection, sepsis, or death in low-income and middle-income countries: a modelling analysis of data from a randomised, multicentre, placebo-controlled trial. Lancet Glob Health. 2025 04; 13(4):e679-e688.
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