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Ramon Lorca Rojas

TitleInstructor
InstitutionUniversity of Colorado Denver - Anschutz Medical Campus
DepartmentSOM-OB/GYN RS GENERAL OPS
Phone303/724-1126

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    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Lorca RA, Houck JA, Laurent LC, Matarazzo CJ, Baker K, Horii M, Nelson KK, Bales ES, Euser AG, Parast MM, Moore LG, Julian CG. High altitude regulates the expression of AMPK pathways in human placenta. Placenta. 2021 Jan 15; 104:267-276. PMID: 33472134.
      View in: PubMed
    2. Lane SL, Doyle AS, Bales ES, Lorca RA, Julian CG, Moore LG. Increased uterine artery blood flow in hypoxic murine pregnancy is not sufficient to prevent fetal growth restriction†. Biol Reprod. 2020 03 13; 102(3):660-670. PMID: 31711123.
      View in: PubMed
    3. Guerra DD, Bok R, Lorca RA, Hurt KJ. Protein kinase A facilitates relaxation of mouse ileum via phosphorylation of neuronal nitric oxide synthase. Br J Pharmacol. 2020 06; 177(12):2765-2778. PMID: 31975425.
      View in: PubMed
    4. Lane SL, Doyle AS, Bales ES, Houck JA, Lorca RA, Moore LG, Julian CG. Peroxisome proliferator-activated receptor gamma blunts endothelin-1-mediated contraction of the uterine artery in a murine model of high-altitude pregnancy. FASEB J. 2020 03; 34(3):4283-4292. PMID: 31970838.
      View in: PubMed
    5. Vaughan OR, Thompson F, Lorca RA, Julian CG, Powell TL, Moore LG, Jansson T. Effect of high altitude on human placental amino acid transport. J Appl Physiol (1985). 2020 01 01; 128(1):127-133. PMID: 31804891.
      View in: PubMed
    6. Guerra DD, Bok R, Vyas V, Orlicky DJ, Lorca RA, Hurt KJ. Akt phosphorylation of neuronal nitric oxide synthase regulates gastrointestinal motility in mouse ileum. Proc Natl Acad Sci U S A. 2019 08 27; 116(35):17541-17546. PMID: 31405982.
      View in: PubMed
    7. Lorca RA, Lane SL, Bales ES, Nsier H, Yi H, Donnelly MA, Euser AG, Julian CG, Moore LG. High Altitude Reduces NO-Dependent Myometrial Artery Vasodilator Response During Pregnancy. Hypertension. 2019 06; 73(6):1319-1326. PMID: 31006328.
      View in: PubMed
    8. Lane SL, Dodson RB, Doyle AS, Park H, Rathi H, Matarrazo CJ, Moore LG, Lorca RA, Wolfson GH, Julian CG. Pharmacological activation of peroxisome proliferator-activated receptor ? (PPAR-?) protects against hypoxia-associated fetal growth restriction. FASEB J. 2019 08; 33(8):8999-9007. PMID: 31039323.
      View in: PubMed
    9. Lorca RA, Wakle-Prabagaran M, Freeman WE, Pillai MK, England SK. The large-conductance voltage- and Ca2+ -activated K+ channel and its ?1-subunit modulate mouse uterine artery function during pregnancy. J Physiol. 2018 03 15; 596(6):1019-1033. PMID: 29319186.
      View in: PubMed
    10. Li Y, Lorca RA, Su EJ. Molecular and cellular underpinnings of normal and abnormal human placental blood flows. J Mol Endocrinol. 2018 01; 60(1):R9-R22. PMID: 29097590.
      View in: PubMed
    11. Lorca RA, Ma X, England SK. The unique N-terminal sequence of the BKCa channel a-subunit determines its modulation by ß-subunits. PLoS One. 2017; 12(7):e0182068. PMID: 28750098.
      View in: PubMed
    12. Wakle-Prabagaran M, Lorca RA, Ma X, Stamnes SJ, Amazu C, Hsiao JJ, Karch CM, Hyrc KL, Wright ME, England SK. BKCa channel regulates calcium oscillations induced by alpha-2-macroglobulin in human myometrial smooth muscle cells. Proc Natl Acad Sci U S A. 2016 Apr 19; 113(16):E2335-44. PMID: 27044074.
      View in: PubMed
    13. Yao J, Shcherbakova DM, Li C, Krumholz A, Lorca RA, Reinl E, England SK, Verkhusha VV, Wang LV. Reversibly switchable fluorescence microscopy with enhanced resolution and image contrast. J Biomed Opt. 2014 Aug; 19(8):086018. PMID: 25144452.
      View in: PubMed
    14. Lorca RA, Prabagaran M, England SK. Functional insights into modulation of BKCa channel activity to alter myometrial contractility. Front Physiol. 2014; 5:289. PMID: 25132821.
      View in: PubMed
    15. Li Y, Lorca RA, Ma X, Rhodes A, England SK. BK channels regulate myometrial contraction by modulating nuclear translocation of NF-?B. Endocrinology. 2014 Aug; 155(8):3112-22. PMID: 24914944.
      View in: PubMed
    16. Lorca RA, Stamnes SJ, Pillai MK, Hsiao JJ, Wright ME, England SK. N-terminal isoforms of the large-conductance Ca²?-activated K? channel are differentially modulated by the auxiliary ß1-subunit. J Biol Chem. 2014 Apr 04; 289(14):10095-103. PMID: 24569989.
      View in: PubMed
    17. Decker AR, McNeill MS, Lambert AM, Overton JD, Chen YC, Lorca RA, Johnson NA, Brockerhoff SE, Mohapatra DP, MacArthur H, Panula P, Masino MA, Runnels LW, Cornell RA. Abnormal differentiation of dopaminergic neurons in zebrafish trpm7 mutant larvae impairs development of the motor pattern. Dev Biol. 2014 Feb 15; 386(2):428-39. PMID: 24291744.
      View in: PubMed
    18. Ketsawatsomkron P, Lorca RA, Keen HL, Weatherford ET, Liu X, Pelham CJ, Grobe JL, Faraci FM, England SK, Sigmund CD. PPAR? regulates resistance vessel tone through a mechanism involving RGS5-mediated control of protein kinase C and BKCa channel activity. Circ Res. 2012 Nov 09; 111(11):1446-58. PMID: 22962432.
      View in: PubMed
    19. Loo L, Shepherd AJ, Mickle AD, Lorca RA, Shutov LP, Usachev YM, Mohapatra DP. The C-type natriuretic peptide induces thermal hyperalgesia through a noncanonical Gß?-dependent modulation of TRPV1 channel. J Neurosci. 2012 Aug 29; 32(35):11942-55. PMID: 22933780.
      View in: PubMed
    20. Lorca RA, Varela-Nallar L, Inestrosa NC, Huidobro-Toro JP. The Cellular Prion Protein Prevents Copper-Induced Inhibition of P2X(4) Receptors. Int J Alzheimers Dis. 2011; 2011:706576. PMID: 22114745.
      View in: PubMed
    21. Lorca RA, Rozas C, Loyola S, Moreira-Ramos S, Zeise ML, Kirkwood A, Huidobro-Toro JP, Morales B. Zinc enhances long-term potentiation through P2X receptor modulation in the hippocampal CA1 region. Eur J Neurosci. 2011 Apr; 33(7):1175-1185. PMID: 21324005.
      View in: PubMed
    22. Yang J, Huang J, Maity B, Gao Z, Lorca RA, Gudmundsson H, Li J, Stewart A, Swaminathan PD, Ibeawuchi SR, Shepherd A, Chen CK, Kutschke W, Mohler PJ, Mohapatra DP, Anderson ME, Fisher RA. RGS6, a modulator of parasympathetic activation in heart. Circ Res. 2010 Nov 26; 107(11):1345-9. PMID: 20864673.
      View in: PubMed
    23. Kalashnikova E, Lorca RA, Kaur I, Barisone GA, Li B, Ishimaru T, Trimmer JS, Mohapatra DP, Díaz E. SynDIG1: an activity-regulated, AMPA- receptor-interacting transmembrane protein that regulates excitatory synapse development. Neuron. 2010 Jan 14; 65(1):80-93. PMID: 20152115.
      View in: PubMed
    24. Arias-Cavieres A, Rozas C, Reyes-Parada M, Barrera N, Pancetti F, Loyola S, Lorca RA, Zeise ML, Morales B. MDMA ("ecstasy") impairs learning in the Morris Water Maze and reduces hippocampal LTP in young rats. Neurosci Lett. 2010 Jan 29; 469(3):375-9. PMID: 20026184.
      View in: PubMed
    25. Tsai AG, Wadden TA, Sarwer DB, Berkowitz RI, Womble LG, Hesson LA, Phelan S, Rothman R. Metabolic syndrome and health-related quality of life in obese individuals seeking weight reduction. Obesity (Silver Spring). 2008 Jan; 16(1):59-63. PMID: 12694397.
      View in: PubMed
    26. Huidobro-Toro JP, Lorca RA, Coddou C. Trace metals in the brain: allosteric modulators of ligand-gated receptor channels, the case of ATP-gated P2X receptors. Eur Biophys J. 2008 Mar; 37(3):301-14. PMID: 17972073.
      View in: PubMed
    27. Lorca RA, Coddou C, Gazitúa MC, Bull P, Arredondo C, Huidobro-Toro JP. Extracellular histidine residues identify common structural determinants in the copper/zinc P2X2 receptor modulation. J Neurochem. 2005 Oct; 95(2):499-512. PMID: 16190872.
      View in: PubMed
    28. Coddou C, Lorca RA, Acuña-Castillo C, Grauso M, Rassendren F, Huidobro-Toro JP. Heavy metals modulate the activity of the purinergic P2X4 receptor. Toxicol Appl Pharmacol. 2005 Jan 15; 202(2):121-31. PMID: 15629187.
      View in: PubMed
    29. Chacón MA, Barría MI, Lorca R, Huidobro-Toro JP, Inestrosa NC. A human prion protein peptide (PrP(59-91)) protects against copper neurotoxicity. Mol Psychiatry. 2003 Oct; 8(10):853-62, 835. PMID: 14515136.
      View in: PubMed
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