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Breck A. Duerkop

TitleAsst Professor
InstitutionUniversity of Colorado Denver - Anschutz Medical Campus
DepartmentSOM-Immunology Microbiology

    Collapse Research 
    Collapse research activities and funding
    F32DK089718     (DUERKOP, BRECK A)Jul 1, 2010 - Jun 30, 2013
    Interactions of a commensal bacterium with the intestinal mucosal surface
    Role: Principal Investigator

    K01DK102436     (DUERKOP, BRECK A)Sep 15, 2014 - Aug 31, 2019
    The contribution of bacteriophages to host-microbe interactions in the intestine
    Role: Principal Investigator

    R01AI141479     (DUERKOP, BRECK A)Sep 14, 2018 - Aug 31, 2023
    Mechanistic basis of bacteriophages for the decolonization of vancomycin resistant enterococci in the intestine.
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    List All   |   Timeline
    1. Chatterjee A, Johnson CN, Luong P, Hullahalli K, McBride SW, Schubert AM, Palmer KL, Carlson PE, Duerkop BA. Bacteriophage resistance alters antibiotic mediated intestinal expansion of enterococci. Infect Immun. 2019 Apr 01. PMID: 30936157.
      View in: PubMed
    2. Chatterjee A, Duerkop BA. Sugar and Fatty Acids Ack-celerate Prophage Induction. Cell Host Microbe. 2019 Feb 13; 25(2):175-176. PMID: 30763529.
      View in: PubMed
    3. Duerkop BA. Bacteriophages shift the focus of the mammalian microbiota. PLoS Pathog. 2018 10; 14(10):e1007310. PMID: 30359456.
      View in: PubMed
    4. Duerkop BA, Kleiner M, Paez-Espino D, Zhu W, Bushnell B, Hassell B, Winter SE, Kyrpides NC, Hooper LV. Murine colitis reveals a disease-associated bacteriophage community. Nat Microbiol. 2018 Sep; 3(9):1023-1031. PMID: 30038310.
      View in: PubMed
    5. Chatterjee A, Duerkop BA. Beyond Bacteria: Bacteriophage-Eukaryotic Host Interactions Reveal Emerging Paradigms of Health and Disease. Front Microbiol. 2018; 9:1394. PMID: 29997604.
      View in: PubMed
    6. Zhu W, Winter MG, Byndloss MX, Spiga L, Duerkop BA, Hughes ER, Büttner L, de Lima Romão E, Behrendt CL, Lopez CA, Sifuentes-Dominguez L, Huff-Hardy K, Wilson RP, Gillis CC, Tükel Ç, Koh AY, Burstein E, Hooper LV, Bäumler AJ, Winter SE. Precision editing of the gut microbiota ameliorates colitis. Nature. 2018 01 11; 553(7687):208-211. PMID: 29323293.
      View in: PubMed
    7. Hughes ER, Winter MG, Duerkop BA, Spiga L, Furtado de Carvalho T, Zhu W, Gillis CC, Büttner L, Smoot MP, Behrendt CL, Cherry S, Santos RL, Hooper LV, Winter SE. Microbial Respiration and Formate Oxidation as Metabolic Signatures of Inflammation-Associated Dysbiosis. Cell Host Microbe. 2017 Feb 08; 21(2):208-219. PMID: 28182951.
      View in: PubMed
    8. Duerkop BA, Huo W, Bhardwaj P, Palmer KL, Hooper LV. Molecular Basis for Lytic Bacteriophage Resistance in Enterococci. MBio. 2016 08 30; 7(4). PMID: 27578757; PMCID: PMC4999554.
    9. Kleiner M, Hooper LV, Duerkop BA. Evaluation of methods to purify virus-like particles for metagenomic sequencing of intestinal viromes. BMC Genomics. 2015 Jan 22; 16:7. PMID: 25608871; PMCID: PMC4308010.
    10. Duerkop BA, Hooper LV. Resident viruses and their interactions with the immune system. Nat Immunol. 2013 Jul; 14(7):654-9. PMID: 23778792; PMCID: PMC3760236.
    11. Duerkop BA, Clements CV, Rollins D, Rodrigues JL, Hooper LV. A composite bacteriophage alters colonization by an intestinal commensal bacterium. Proc Natl Acad Sci U S A. 2012 Oct 23; 109(43):17621-6. PMID: 23045666; PMCID: PMC3491505.
    12. McClean AE, Duerkop BA, Greenberg EP, Kluepfel DA. AHL signals induce rubrifacine production in a bruI mutant of Brenneria rubrifaciens. Phytopathology. 2012 Feb; 102(2):195-203. PMID: 22236075.
      View in: PubMed
    13. Seyedsayamdost MR, Chandler JR, Blodgett JA, Lima PS, Duerkop BA, Oinuma K, Greenberg EP, Clardy J. Quorum-sensing-regulated bactobolin production by Burkholderia thailandensis E264. Org Lett. 2010 Feb 19; 12(4):716-9. PMID: 20095633; PMCID: PMC2821070.
    14. Duerkop BA, Vaishnava S, Hooper LV. Immune responses to the microbiota at the intestinal mucosal surface. Immunity. 2009 Sep 18; 31(3):368-76. PMID: 19766080.
      View in: PubMed
    15. Chandler JR, Duerkop BA, Hinz A, West TE, Herman JP, Churchill ME, Skerrett SJ, Greenberg EP. Mutational analysis of Burkholderia thailandensis quorum sensing and self-aggregation. J Bacteriol. 2009 Oct; 191(19):5901-9. PMID: 19648250; PMCID: PMC2747893.
    16. Duerkop BA, Varga J, Chandler JR, Peterson SB, Herman JP, Churchill ME, Parsek MR, Nierman WC, Greenberg EP. Quorum-sensing control of antibiotic synthesis in Burkholderia thailandensis. J Bacteriol. 2009 Jun; 191(12):3909-18. PMID: 19376863; PMCID: PMC2698390.
    17. Duerkop BA, Herman JP, Ulrich RL, Churchill ME, Greenberg EP. The Burkholderia mallei BmaR3-BmaI3 quorum-sensing system produces and responds to N-3-hydroxy-octanoyl homoserine lactone. J Bacteriol. 2008 Jul; 190(14):5137-41. PMID: 18487338; PMCID: PMC2447019.
    18. Duerkop BA, Ulrich RL, Greenberg EP. Octanoyl-homoserine lactone is the cognate signal for Burkholderia mallei BmaR1-BmaI1 quorum sensing. J Bacteriol. 2007 Jul; 189(14):5034-40. PMID: 17496085; PMCID: PMC1951878.
    19. Chang HK, Thalhofer C, Duerkop BA, Mehling JS, Verma S, Gollob KJ, Almeida R, Wilson ME. Oxidant generation by single infected monocytes after short-term fluorescence labeling of a protozoan parasite. Infect Immun. 2007 Feb; 75(2):1017-24. PMID: 17118986; PMCID: PMC1828521.
    20. Müh U, Hare BJ, Duerkop BA, Schuster M, Hanzelka BL, Heim R, Olson ER, Greenberg EP. A structurally unrelated mimic of a Pseudomonas aeruginosa acyl-homoserine lactone quorum-sensing signal. Proc Natl Acad Sci U S A. 2006 Nov 07; 103(45):16948-52. PMID: 17075036; PMCID: PMC1636559.
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