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Christian D Young

InstitutionUniversity of Colorado Denver - Anschutz Medical Campus

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Li F, Bian L, Iriyama S, Jian Z, Fan B, Luo JJ, Wang DD, Young CD, Han G, Wang XJ. Smad7 ameliorates TGFß-mediated skin inflammation and associated wound healing defects but not the susceptibility to experimental skin carcinogenesis. J Invest Dermatol. 2018 Nov 10. PMID: 30423327.
      View in: PubMed
    2. Luo J, Bian L, Blevins MA, Wang D, Liang C, Du D, Wu F, Holwerda B, Zhao R, Raben D, Zhou H, Young CD, Wang XJ. Smad7 Promotes Healing of Radiotherapy-Induced Oral Mucositis without Compromising Oral Cancer Therapy in a Xenograft Mouse Model. Clin Cancer Res. 2019 Jan 15; 25(2):808-818. PMID: 30185419.
      View in: PubMed
    3. Schwarz LJ, Hutchinson KE, Rexer BN, Estrada MV, Gonzalez Ericsson PI, Sanders ME, Dugger TC, Formisano L, Guerrero-Zotano A, Red-Brewer M, Young CD, Lantto J, Pedersen MW, Kragh M, Horak ID, Arteaga CL. An ERBB1-3 Neutralizing Antibody Mixture With High Activity Against Drug-Resistant HER2+ Breast Cancers With ERBB Ligand Overexpression. J Natl Cancer Inst. 2017 Nov 01; 109(11). PMID: 29059433.
      View in: PubMed
    4. Morrison Joly M, Williams MM, Hicks DJ, Jones B, Sanchez V, Young CD, Sarbassov DD, Muller WJ, Brantley-Sieders D, Cook RS. Two distinct mTORC2-dependent pathways converge on Rac1 to drive breast cancer metastasis. Breast Cancer Res. 2017 Jun 30; 19(1):74. PMID: 28666462.
      View in: PubMed
    5. Young CD, Arteaga CL, Cook RS. Dual inhibition of Type I and Type III PI3 kinases increases tumor cell apoptosis in HER2+ breast cancers. Breast Cancer Res. 2015 Dec 04; 17:148. PMID: 26637440; PMCID: PMC4670529.
    6. Morrison MM, Young CD, Wang S, Sobolik T, Sanchez VM, Hicks DJ, Cook RS, Brantley-Sieders DM. mTOR Directs Breast Morphogenesis through the PKC-alpha-Rac1 Signaling Axis. PLoS Genet. 2015 Jul; 11(7):e1005291. PMID: 26132202; PMCID: PMC4488502.
    7. Young CD, Pfefferle AD, Owens P, Kuba MG, Rexer BN, Balko JM, Sánchez V, Cheng H, Perou CM, Zhao JJ, Cook RS, Arteaga CL. Conditional loss of ErbB3 delays mammary gland hyperplasia induced by mutant PIK3CA without affecting mammary tumor latency, gene expression, or signaling. Cancer Res. 2013 Jul 01; 73(13):4075-85. PMID: 23633485; PMCID: PMC3702683.
    8. Young CD, Lewis AS, Rudolph MC, Ruehle MD, Jackman MR, Yun UJ, Ilkun O, Pereira R, Abel ED, Anderson SM. Modulation of glucose transporter 1 (GLUT1) expression levels alters mouse mammary tumor cell growth in vitro and in vivo. PLoS One. 2011; 6(8):e23205. PMID: 21826239; PMCID: PMC3149640.
    9. Lambert JR, Eddy VJ, Young CD, Persons KS, Sarkar S, Kelly JA, Genova E, Lucia MS, Faller DV, Ray R. A vitamin D receptor-alkylating derivative of 1a,25-dihydroxyvitamin D3 inhibits growth of human kidney cancer cells and suppresses tumor growth. Cancer Prev Res (Phila). 2010 Dec; 3(12):1596-607. PMID: 21149334; PMCID: PMC3059596.
    10. Nelson AC, Lyons TR, Young CD, Hansen KC, Anderson SM, Holt JT. AKT regulates BRCA1 stability in response to hormone signaling. Mol Cell Endocrinol. 2010 May 05; 319(1-2):129-42. PMID: 20085797; PMCID: PMC4548798.
    11. Young CD, Anderson SM. Rah, rah, ROS: metabolic changes caused by loss of adhesion induce cell death. Breast Cancer Res. 2009; 11(6):307. PMID: 19930622; PMCID: PMC2815538.
    12. Young CD, Nolte EC, Lewis A, Serkova NJ, Anderson SM. Activated Akt1 accelerates MMTV-c-ErbB2 mammary tumourigenesis in mice without activation of ErbB3. Breast Cancer Res. 2008; 10(4):R70. PMID: 18700973; PMCID: PMC2575543.
    13. Young CD, Anderson SM. Sugar and fat - that's where it's at: metabolic changes in tumors. Breast Cancer Res. 2008; 10(1):202. PMID: 18304378; PMCID: PMC2374962.
    14. Lambert JR, Young CD, Persons KS, Ray R. Mechanistic and pharmacodynamic studies of a 25-hydroxyvitamin D3 derivative in prostate cancer cells. Biochem Biophys Res Commun. 2007 Sep 14; 361(1):189-95. PMID: 17658477.
      View in: PubMed
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