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Search Results to Joseph Falke

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One or more keywords matched the following items that are connected to Falke, Joseph

Item TypeName
Academic Article C2 domains from different Ca2+ signaling pathways display functional and mechanistic diversity.
Academic Article The C2 domain calcium-binding motif: structural and functional diversity.
Academic Article C2 domains of protein kinase C isoforms alpha, beta, and gamma: activation parameters and calcium stoichiometries of the membrane-bound state.
Academic Article C2 domain of protein kinase C alpha: elucidation of the membrane docking surface by site-directed fluorescence and spin labeling.
Academic Article Specific translocation of protein kinase Calpha to the plasma membrane requires both Ca2+ and PIP2 recognition by its C2 domain.
Academic Article Ca2+ influx is an essential component of the positive-feedback loop that maintains leading-edge structure and activity in macrophages.
Academic Article Effect of PIP2 binding on the membrane docking geometry of PKC alpha C2 domain: an EPR site-directed spin-labeling and relaxation study.
Academic Article Molecular mechanism of an oncogenic mutation that alters membrane targeting: Glu17Lys modifies the PIP lipid specificity of the AKT1 PH domain.
Academic Article The GRP1 PH domain, like the AKT1 PH domain, possesses a sentry glutamate residue essential for specific targeting to plasma membrane PI(3,4,5)P(3).
Academic Article Mechanism of specific membrane targeting by C2 domains: localized pools of target lipids enhance Ca2+ affinity.
Academic Article Membrane docking geometry and target lipid stoichiometry of membrane-bound PKCa C2 domain: a combined molecular dynamics and experimental study.
Concept Protein Kinase C
Concept Protein Kinase C-alpha
Concept Proto-Oncogene Proteins c-akt
Academic Article Lateral diffusion of peripheral membrane proteins on supported lipid bilayers is controlled by the additive frictional drags of (1) bound lipids and (2) protein domains penetrating into the bilayer hydrocarbon core.
Academic Article Single-molecule studies reveal a hidden key step in the activation mechanism of membrane-bound protein kinase C-a.
Academic Article Interactions of protein kinase C-a C1A and C1B domains with membranes: a combined computational and experimental study.
Academic Article Regulation of PI3K by PKC and MARCKS: Single-Molecule Analysis of a Reconstituted Signaling Pathway.
Grant Mechanisms of Signaling on Membrane Surfaces
Academic Article A PKC-MARCKS-PI3K regulatory module links Ca2+ and PIP3 signals at the leading edge of polarized macrophages.
Concept Protein Kinase C beta
Academic Article PDK1:PKCa heterodimer association-dissociation dynamics in single-molecule diffusion tracks on a target membrane.

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  • Proto Oncogene Proteins c akt

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