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Search Results to Joseph Falke

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Falke, Joseph

One or more keywords matched the following items that are connected to Falke, Joseph

Item Type	Name
Academic Article	Specific translocation of protein kinase Calpha to the plasma membrane requires both Ca2+ and PIP2 recognition by its C2 domain.
Academic Article	Ca2+ influx is an essential component of the positive-feedback loop that maintains leading-edge structure and activity in macrophages.
Academic Article	Effect of PIP2 binding on the membrane docking geometry of PKC alpha C2 domain: an EPR site-directed spin-labeling and relaxation study.
Academic Article	Molecular mechanism of an oncogenic mutation that alters membrane targeting: Glu17Lys modifies the PIP lipid specificity of the AKT1 PH domain.
Academic Article	The GRP1 PH domain, like the AKT1 PH domain, possesses a sentry glutamate residue essential for specific targeting to plasma membrane PI(3,4,5)P(3).
Academic Article	Mechanism of specific membrane targeting by C2 domains: localized pools of target lipids enhance Ca2+ affinity.
Academic Article	Single-molecule fluorescence studies of a PH domain: new insights into the membrane docking reaction.
Academic Article	Membrane docking geometry and target lipid stoichiometry of membrane-bound PKCa C2 domain: a combined molecular dynamics and experimental study.
Concept	Phosphatidylinositols
Concept	Phosphatidylinositol 4,5-Diphosphate
Concept	Phosphatidylinositol 3-Kinases
Concept	Phosphatidylinositol Phosphates
Academic Article	Molecular mechanism of membrane binding of the GRP1 PH domain.
Academic Article	Interplay between phosphoinositide lipids and calcium signals at the leading edge of chemotaxing ameboid cells.
Academic Article	Regulation of PI3K by PKC and MARCKS: Single-Molecule Analysis of a Reconstituted Signaling Pathway.
Academic Article	Regulation of a Coupled MARCKS-PI3K Lipid Kinase Circuit by Calmodulin: Single-Molecule Analysis of a Membrane-Bound Signaling Module.
Grant	Mechanisms of Signaling on Membrane Surfaces
Academic Article	Single-Molecule Study Reveals How Receptor and Ras Synergistically Activate PI3Ka and PIP3 Signaling.
Academic Article	A PKC-MARCKS-PI3K regulatory module links Ca2+ and PIP3 signals at the leading edge of polarized macrophages.
Concept	Class III Phosphatidylinositol 3-Kinases
Concept	Phosphatidylinositol 3-Kinase
Academic Article	The G-Protein Rab5A Activates VPS34 Complex II, a Class III PI3K, by a Dual Regulatory Mechanism.
Academic Article	Binding of active Ras and its mutants to the Ras binding domain of PI-3-kinase: A quantitative approach to KD measurements.

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Phosphatidylinositols