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Search Results to Joseph Falke

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Falke, Joseph

One or more keywords matched the following items that are connected to Falke, Joseph

Item Type	Name
Academic Article	Lock on/off disulfides identify the transmembrane signaling helix of the aspartate receptor.
Academic Article	Transmembrane signaling by the aspartate receptor: engineered disulfides reveal static regions of the subunit interface.
Academic Article	Kinetic tuning of the EF-hand calcium binding motif: the gateway residue independently adjusts (i) barrier height and (ii) equilibrium.
Academic Article	Tuning the equilibrium ion affinity and selectivity of the EF-hand calcium binding motif: substitutions at the gateway position.
Academic Article	Identification of a site critical for kinase regulation on the central processing unit (CPU) helix of the aspartate receptor.
Academic Article	Structure and dynamics of Escherichia coli chemosensory receptors. Engineered sulfhydryl studies.
Academic Article	Signaling domain of the aspartate receptor is a helical hairpin with a localized kinase docking surface: cysteine and disulfide scanning studies.
Academic Article	Attractant regulation of the aspartate receptor-kinase complex: limited cooperative interactions between receptors and effects of the receptor modification state.
Academic Article	Optimizing the metal binding parameters of an EF-hand-like calcium chelation loop: coordinating side chains play a more important tuning role than chelation loop flexibility.
Academic Article	Membrane orientation and position of the C2 domain from cPLA2 by site-directed spin labeling.
Academic Article	Cysteine and disulfide scanning reveals a regulatory alpha-helix in the cytoplasmic domain of the aspartate receptor.
Academic Article	C2 domain of protein kinase C alpha: elucidation of the membrane docking surface by site-directed fluorescence and spin labeling.
Academic Article	Thermal motions of surface alpha-helices in the D-galactose chemosensory receptor. Detection by disulfide trapping.
Academic Article	Side chains at the membrane-water interface modulate the signaling state of a transmembrane receptor.
Academic Article	Conserved glycine residues in the cytoplasmic domain of the aspartate receptor play essential roles in kinase coupling and on-off switching.
Academic Article	Evidence that the adaptation region of the aspartate receptor is a dynamic four-helix bundle: cysteine and disulfide scanning studies.
Academic Article	Use of site-directed cysteine and disulfide chemistry to probe protein structure and dynamics: applications to soluble and transmembrane receptors of bacterial chemotaxis.
Academic Article	Effect of PIP2 binding on the membrane docking geometry of PKC alpha C2 domain: an EPR site-directed spin-labeling and relaxation study.
Academic Article	Thermal domain motions of CheA kinase in solution: Disulfide trapping reveals the motional constraints leading to trans-autophosphorylation.
Academic Article	OS-FRET: a new one-sample method for improved FRET measurements.
Academic Article	The GRP1 PH domain, like the AKT1 PH domain, possesses a sentry glutamate residue essential for specific targeting to plasma membrane PI(3,4,5)P(3).
Academic Article	Membrane docking geometry of GRP1 PH domain bound to a target lipid bilayer: an EPR site-directed spin-labeling and relaxation study.
Academic Article	Membrane-docking loops of the cPLA2 C2 domain: detailed structural analysis of the protein-membrane interface via site-directed spin-labeling.
Academic Article	Location of the membrane-docking face on the Ca2+-activated C2 domain of cytosolic phospholipase A2.
Academic Article	Mapping out regions on the surface of the aspartate receptor that are essential for kinase activation.
Academic Article	Engineered socket study of signaling through a four-helix bundle: evidence for a yin-yang mechanism in the kinase control module of the aspartate receptor.
Concept	Mutagenesis, Site-Directed
Concept	Mutagenesis
Academic Article	Structure, function, and on-off switching of a core unit contact between CheA kinase and CheW adaptor protein in the bacterial chemosensory array: A disulfide mapping and mutagenesis study.
Academic Article	Increasing and decreasing the ultrastability of bacterial chemotaxis core signaling complexes by modifying protein-protein contacts.

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Mutagenesis