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Search Results to Leslie Anne Leinwand

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Leinwand, Leslie

One or more keywords matched the following items that are connected to Leinwand, Leslie

Item Type	Name
Academic Article	Cloning and characterization of a nonmuscle myosin heavy chain cDNA.
Academic Article	Multigene family for sarcomeric myosin heavy chain in mouse and human DNA: localization on a single chromosome.
Academic Article	Cardiac alpha-myosin heavy chains differ in their induction of myocarditis. Identification of pathogenic epitopes.
Academic Article	Fast myosin heavy chains expressed in secondary mammalian muscle fibers at the time of their inception.
Academic Article	Three slow myosin heavy chains sequentially expressed in developing mammalian skeletal muscle.
Academic Article	Post-transcriptional regulation of rat alpha cardiac myosin heavy chain gene expression.
Academic Article	Rat liver fat-storing cell lines express sarcomeric myosin heavy chain mRNA and protein.
Academic Article	Sarcomeric myosin heavy chain expressed in nonmuscle cells forms thick filaments in the presence of substoichiometric amounts of light chains.
Academic Article	Distinct behavior of cardiac myosin heavy chain gene constructs in vivo. Discordance with in vitro results.
Academic Article	Prospects for gene therapy with direct injection of polynucleotides.
Academic Article	Isolation and characterization of human myosin heavy chain genes.
Academic Article	Mice expressing mutant myosin heavy chains are a model for familial hypertrophic cardiomyopathy.
Academic Article	The mammalian myosin heavy chain gene family.
Academic Article	A 29 residue region of the sarcomeric myosin rod is necessary for filament formation.
Academic Article	The vertebrate myosin heavy chain: genetics and assembly properties.
Academic Article	Direct gene transfer into the mouse heart.
Academic Article	Myosin heavy chains IIa and IId are functionally distinct in the mouse.
Academic Article	Organization of the human skeletal myosin heavy chain gene cluster.
Academic Article	Organization of human and mouse skeletal myosin heavy chain gene clusters is highly conserved.
Academic Article	Cardiac myosin heavy chains lacking the light chain binding domain cause hypertrophic cardiomyopathy in mice.
Academic Article	Myosin heavy chain isoform expression in the failing and nonfailing human heart.
Academic Article	Spatial and temporal changes in myosin heavy chain gene expression in skeletal muscle development.
Academic Article	Inactivation of myosin heavy chain genes in the mouse: diverse and unexpected phenotypes.
Academic Article	Postnatal myosin heavy chain isoform expression in normal mice and mice null for IIb or IId myosin heavy chains.
Academic Article	Mutation of the IIB myosin heavy chain gene results in muscle fiber loss and compensatory hypertrophy.
Academic Article	Animal models of hypertrophic cardiomyopathy.
Academic Article	Modulation of myosin filament organization by C-protein family members.
Academic Article	Four sarcomeric myosin heavy chain genes are expressed by human fetal skeletal muscle cells differentiating in culture.
Academic Article	Different pathways regulate expression of the skeletal myosin heavy chain genes.
Academic Article	Cardiac and skeletal muscle adaptations to voluntary wheel running in the mouse.
Academic Article	Skeletal muscle adaptations in response to voluntary wheel running in myosin heavy chain null mice.
Academic Article	Growth and muscle defects in mice lacking adult myosin heavy chain genes.
Academic Article	Myosin heavy chain gene expression in human heart failure.
Academic Article	Functional analysis of myosin mutations that cause familial hypertrophic cardiomyopathy.
Academic Article	Yin Yang 1 is increased in human heart failure and represses the activity of the human alpha-myosin heavy chain promoter.
Academic Article	Myocyte enhancer factor-2 and serum response factor binding elements regulate fast Myosin heavy chain transcription in vivo.
Academic Article	Yin Yang 1 represses alpha-myosin heavy chain gene expression in pathologic cardiac hypertrophy.
Academic Article	Soy diet worsens heart disease in mice.
Academic Article	Exercise can prevent and reverse the severity of hypertrophic cardiomyopathy.
Academic Article	Diversity in transcriptional start site selection and alternative splicing affects the 5'-UTR of mouse striated muscle myosin transcripts.
Academic Article	Mutations in the beta-myosin rod cause myosin storage myopathy via multiple mechanisms.
Academic Article	The role of MEKK1 in hypertrophic cardiomyopathy.
Academic Article	Expression of the beta (slow)-isoform of MHC in the adult mouse heart causes dominant-negative functional effects.
Academic Article	Full-length rat alpha and beta cardiac myosin heavy chain sequences. Comparisons suggest a molecular basis for functional differences.
Academic Article	Gender and aging in a transgenic mouse model of hypertrophic cardiomyopathy.
Academic Article	IIb or not IIb? Regulation of myosin heavy chain gene expression in mice and men.
Academic Article	Low sequence variation in the gene encoding the human beta-myosin heavy chain.
Academic Article	Expression and DNA sequence analysis of a human embryonic skeletal muscle myosin heavy chain gene.
Academic Article	Intracellular calcium and myosin isoform transitions. Calcineurin and calcium-calmodulin kinase pathways regulate preferential activation of the IIa myosin heavy chain promoter.
Academic Article	Complete nucleotide sequence of full length cDNA for rat alpha cardiac myosin heavy chain.
Academic Article	Complete nucleotide sequence of full length cDNA for rat beta cardiac myosin heavy chain.
Academic Article	A polymorphic human myosin heavy chain locus is linked to an anonymous single copy locus (D17S1) at 17p13.
Academic Article	Coexpression and assembly of myosin heavy chain and myosin light chain in Escherichia coli.
Academic Article	Skeletal muscle adaptations to microgravity exposure in the mouse.
Academic Article	Type IIx myosin heavy chain transcripts are expressed in type IIb fibers of human skeletal muscle.
Academic Article	Skeletal myosin heavy chain function in cultured lung myofibroblasts.
Academic Article	A murine model for hypertrophic cardiomyopathy.
Academic Article	The Ku protein complex interacts with YY1, is up-regulated in human heart failure, and represses alpha myosin heavy-chain gene expression.
Academic Article	Comparative sequence analysis of the complete human sarcomeric myosin heavy chain family: implications for functional diversity.
Academic Article	MyoD, Myf5, and the calcineurin pathway activate the developmental myosin heavy chain genes.
Academic Article	Cardiac troponin T mutations result in allele-specific phenotypes in a mouse model for hypertrophic cardiomyopathy.
Academic Article	Alterations in cardiac adrenergic signaling and calcium cycling differentially affect the progression of cardiomyopathy.
Academic Article	Blocking cardiac growth in hypertrophic cardiomyopathy induces cardiac dysfunction and decreased survival only in males.
Academic Article	Morphological and functional alterations in ventricular myocytes from male transgenic mice with hypertrophic cardiomyopathy.
Academic Article	Human nonmuscle myosin heavy chain mRNA: generation of diversity through alternative polyadenylylation.
Academic Article	A beta1-adrenergic receptor CaM kinase II-dependent pathway mediates cardiac myocyte fetal gene induction.
Academic Article	Thyroid hormone regulates expression of a transfected human alpha-myosin heavy-chain fusion gene in fetal rat heart cells.
Academic Article	Generation of a full-length human perinatal myosin heavy-chain-encoding cDNA.
Academic Article	Characterization of diverse forms of myosin heavy chain expressed in adult human skeletal muscle.
Academic Article	Bioinformatics assessment of beta-myosin mutations reveals myosin's high sensitivity to mutations.
Academic Article	Uncoupling of expression of an intronic microRNA and its myosin host gene by exon skipping.
Academic Article	Molecular genetic characterization of a developmentally regulated human perinatal myosin heavy chain.
Academic Article	Interferon-? causes cardiac myocyte atrophy via selective degradation of myosin heavy chain in a model of chronic myocarditis.
Academic Article	Human cardiac myosin heavy chain genes and their linkage in the genome.
Academic Article	Myosin heavy chain is not selectively decreased in murine cancer cachexia.
Academic Article	Effects of pathogenic proline mutations on myosin assembly.
Academic Article	Myh7b/miR-499 gene expression is transcriptionally regulated by MRFs and Eos.
Academic Article	Conserved protein domains in a myosin heavy chain gene from Dictyostelium discoideum.
Concept	Myosin Heavy Chains
Academic Article	Molecular consequences of the R453C hypertrophic cardiomyopathy mutation on human ?-cardiac myosin motor function.
Academic Article	The superfast human extraocular myosin is kinetically distinct from the fast skeletal IIa, IIb, and IId isoforms.
Academic Article	The hypertrophic cardiomyopathy myosin mutation R453C alters ATP binding and hydrolysis of human cardiac ?-myosin.
Academic Article	Sex-based differences in skeletal muscle kinetics and fiber-type composition.
Academic Article	Skip residues modulate the structural properties of the myosin rod and guide thick filament assembly.
Academic Article	Prolonged Cre expression driven by the a-myosin heavy chain promoter can be cardiotoxic.
Academic Article	A small-molecule inhibitor of sarcomere contractility suppresses hypertrophic cardiomyopathy in mice.
Academic Article	Two novel MYH7 proline substitutions cause Laing Distal Myopathy-like phenotypes with variable expressivity and neck extensor contracture.
Grant	Molecular characterization of cardiomyopathy mutations in human cardiac myosin
Grant	Myosin Gene Diversity and Function
Grant	Developmental Myosin Heavy Chain Regulation and Function
Grant	IN VIVO MODELS OF CARDIAC GENE REGULATION
Grant	Mechanisms of myopathy caused by mutations in the myosin rod
Academic Article	Dilated cardiomyopathy myosin mutants have reduced force-generating capacity.
Academic Article	The ancient sarcomeric myosins found in specialized muscles.
Academic Article	Expression of Normally Repressed Myosin Heavy Chain 7b in the Mammalian Heart Induces Dilated Cardiomyopathy.
Academic Article	Associations Between Female Sex, Sarcomere Variants, and Clinical Outcomes in Hypertrophic Cardiomyopathy.
Academic Article	Myosin 7b is a regulatory long noncoding RNA (lncMYH7b) in the human heart.
Academic Article	Nonproductive Splicing Prevents Expression of MYH7b Protein in the Mammalian Heart.
Academic Article	Functional divergence of the sarcomeric myosin, MYH7b, supports species-specific biological roles.
Academic Article	Distinct effects of two hearing loss-associated mutations in?the sarcomeric myosin MYH7b.
Academic Article	Divergent Molecular Phenotypes in Point Mutations at the Same Residue in Beta-Myosin Heavy Chain Lead to Distinct Cardiomyopathies.

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Myosin Heavy Chains