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Search Results to Linda R Watkins

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Watkins, Linda

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Item Type	Name
Academic Article	Delta opiate receptors mediate tail-shock induced antinociception at supraspinal levels.
Academic Article	Kappa opiate receptors mediate tail-shock induced antinociception at spinal levels.
Academic Article	Neurocircuitry of conditioned inhibition of analgesia: effects of amygdala, dorsal raphe, ventral medullary, and spinal cord lesions on antianalgesia in the rat.
Academic Article	Implications of immune-to-brain communication for sickness and pain.
Academic Article	Parallel activation of multiple spinal opiate systems appears to mediate 'non-opiate' stress-induced analgesias.
Academic Article	Cholecystokinin antianalgesia: safety cues abolish morphine analgesia.
Academic Article	Spinal cord glia: new players in pain.
Academic Article	Evidence for the involvement of spinal cord glia in subcutaneous formalin induced hyperalgesia in the rat.
Academic Article	Reversal of spinal cord non-opiate analgesia by conditioned anti-analgesia in the rat.
Academic Article	Snake venom phospholipase A2s (Asp49 and Lys49) induce mechanical allodynia upon peri-sciatic administration: involvement of spinal cord glia, proinflammatory cytokines and nitric oxide.
Academic Article	Activation of the spinal cord complement cascade might contribute to mechanical allodynia induced by three animal models of spinal sensitization.
Academic Article	Snake venom components enhance pain upon subcutaneous injection: an initial examination of spinal cord mediators.
Academic Article	Fractalkine (CX3CL1) and fractalkine receptor (CX3CR1) distribution in spinal cord and dorsal root ganglia under basal and neuropathic pain conditions.
Academic Article	Minocycline attenuates mechanical allodynia and proinflammatory cytokine expression in rat models of pain facilitation.
Academic Article	Glia: novel counter-regulators of opioid analgesia.
Academic Article	Involvement of spinal cord nuclear factor kappaB activation in rat models of proinflammatory cytokine-mediated pain facilitation.
Academic Article	Repeated intrathecal injections of plasmid DNA encoding interleukin-10 produce prolonged reversal of neuropathic pain.
Academic Article	Norman Cousins Lecture. Glia as the "bad guys": implications for improving clinical pain control and the clinical utility of opioids.
Academic Article	A role for G protein-coupled receptor kinase 2 in mechanical allodynia.
Academic Article	Phenylephrine-induced antinociception: investigations of potential neural and endocrine bases.
Academic Article	Proinflammatory cytokines oppose opioid-induced acute and chronic analgesia.
Academic Article	Evidence that intrathecal morphine-3-glucuronide may cause pain enhancement via toll-like receptor 4/MD-2 and interleukin-1beta.
Academic Article	Possible involvement of toll-like receptor 4/myeloid differentiation factor-2 activity of opioid inactive isomers causes spinal proinflammation and related behavioral consequences.
Academic Article	Pain intensity and duration can be enhanced by prior challenge: initial evidence suggestive of a role of microglial priming.
Academic Article	A method for increasing the viability of the external portion of lumbar catheters placed in the spinal subarachnoid space of rats.
Academic Article	Spinal upregulation of glutamate transporter GLT-1 by ceftriaxone: therapeutic efficacy in a range of experimental nervous system disorders.
Academic Article	Below level central pain induced by discrete dorsal spinal cord injury.
Academic Article	Thermal hyperalgesia and mechanical allodynia produced by intrathecal administration of the human immunodeficiency virus-1 (HIV-1) envelope glycoprotein, gp120.
Academic Article	Glial activation: a driving force for pathological pain.
Academic Article	Unilateral T13 and L1 dorsal root avulsion: methods for a novel model of central neuropathic pain.
Academic Article	(+)-naloxone, an opioid-inactive toll-like receptor 4 signaling inhibitor, reverses multiple models of chronic neuropathic pain in rats.
Academic Article	Spinal glia and proinflammatory cytokines mediate mirror-image neuropathic pain in rats.
Academic Article	Glial proinflammatory cytokines mediate exaggerated pain states: implications for clinical pain.
Academic Article	Illness-induced hyperalgesia is mediated by spinal neuropeptides and excitatory amino acids.
Academic Article	Intrathecal HIV-1 envelope glycoprotein gp120 induces enhanced pain states mediated by spinal cord proinflammatory cytokines.
Academic Article	A novel immune-to-CNS communication pathway: cells of the meninges surrounding the spinal cord CSF space produce proinflammatory cytokines in response to an inflammatory stimulus.
Academic Article	Interleukin-6 mediates low-threshold mechanical allodynia induced by intrathecal HIV-1 envelope glycoprotein gp120.
Academic Article	Glia: a novel drug discovery target for clinical pain.
Academic Article	A role for proinflammatory cytokines and fractalkine in analgesia, tolerance, and subsequent pain facilitation induced by chronic intrathecal morphine.
Academic Article	Evidence that exogenous and endogenous fractalkine can induce spinal nociceptive facilitation in rats.
Academic Article	An initial investigation of spinal mechanisms underlying pain enhancement induced by fractalkine, a neuronally released chemokine.
Academic Article	Spinal cord glia and interleukin-1 do not appear to mediate persistent allodynia induced by intramuscular acidic saline in rats.
Academic Article	Anti-inflammatory cytokine gene therapy decreases sensory and motor dysfunction in experimental Multiple Sclerosis: MOG-EAE behavioral and anatomical symptom treatment with cytokine gene therapy.
Academic Article	Intrathecal interleukin-10 gene therapy attenuates paclitaxel-induced mechanical allodynia and proinflammatory cytokine expression in dorsal root ganglia in rats.
Academic Article	Intrathecal injection of an alpha seven nicotinic acetylcholine receptor agonist attenuates gp120-induced mechanical allodynia and spinal pro-inflammatory cytokine profiles in rats.
Academic Article	PEGylation of brain-derived neurotrophic factor for preserved biological activity and enhanced spinal cord distribution.
Academic Article	Prior exposure to glucocorticoids potentiates lipopolysaccharide induced mechanical allodynia and spinal neuroinflammation.
Academic Article	Harnessing pain heterogeneity and RNA transcriptome to identify blood-based pain biomarkers: a novel correlational study design and bioinformatics approach in a graded chronic constriction injury model.
Concept	Spinal Cord
Concept	Spinal Cord Injuries
Academic Article	Pioglitazone rapidly reduces neuropathic pain through astrocyte and nongenomic PPAR? mechanisms.
Academic Article	Adenosine 2A receptor agonism: A single intrathecal administration attenuates motor paralysis in experimental autoimmune encephalopathy in rats.
Academic Article	Morphine paradoxically prolongs neuropathic pain in rats by amplifying spinal NLRP3 inflammasome activation.
Academic Article	Morphine amplifies mechanical allodynia via TLR4 in a rat model of spinal cord injury.
Grant	PAIN FACILITATION BY GP120 AND HIV ENVELOPE PROTEIN
Grant	ALLODYNIC EFFECTS OF SCIATIC INFLAMMATORY NEURITIS
Grant	Pain facilitation via neuron-to-glia signaling
Grant	Pain control via spinal interleukin-10 gene therapy
Grant	Immune and Gilia Regulation of Pain & Analgesic Actions
Grant	Spinal adenosine modulator: enduring anti-inflammatory action in neuropathic pain
Grant	Optoid Analgesics: Modulation of Trigeminal &Spinal Glial Activation
Grant	Targeting toll like receptor 4 (TLR4) and TLR2 to resolve EAE-associated paralysis, pain and cognitive deficits: efficacy of a clinically-relevant blood brain barrier permeable TLR4/TLR2 antagonist
Grant	Spinal glia activation in human chronic pain
Grant	Methods Development for Studying Dorsal Spinal Cord Glia
Grant	Exploring the Potential of Glia for Regulating Clinically Relevant Opiod Actions
Academic Article	Exploring acute-to-chronic neuropathic pain in rats after contusion spinal cord injury.
Academic Article	DREADDed microglia in pain: Implications for spinal inflammatory signaling in male rats.
Academic Article	Sustained reversal of central neuropathic pain induced by a single intrathecal injection of adenosine A2A receptor agonists.
Academic Article	Spinal Cord Injury in Rats Disrupts the Circadian System.
Academic Article	Spinal Cord Injury in Rats Dysregulates Diurnal Rhythms of Fecal Output and Liver Metabolic Indicators.
Concept	Spinal Cord Dorsal Horn
Academic Article	Lovastatin inhibits Toll-like receptor 4 signaling in microglia by targeting its co-receptor myeloid differentiation protein 2 and attenuates neuropathic pain.
Academic Article	Toll-like receptor 2 and 4 antagonism for the treatment of experimental autoimmune encephalomyelitis (EAE)-related pain.
Academic Article	Aging and miR-155 in mice influence survival and neuropathic pain after spinal cord injury.
Academic Article	Interleukin-1beta and inflammasome expression in spinal cord following chronic constriction injury in male and female rats.

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Spinal Cord